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PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. e51992
The polyglutamic acid/peptoid 1 (QM56) nanoconjugate inhibits apoptosis by interfering with Apaf-1 binding to procaspase-9. We now describe anti-inflammatory... 
CYTOCHROME-C | ACUTE KIDNEY INJURY | APOPTOSIS | RECRUITMENT | COMPLEX | MULTIDISCIPLINARY SCIENCES | ALPHA | ACTIVATING FACTOR-1 APAF-1 | INHIBITORS | NF-KAPPA-B | EXPRESSION | Cell Line | Inflammation - pathology | Peptoids - pharmacology | Kidney - pathology | Nanoparticles - chemistry | Anti-Inflammatory Agents - pharmacology | Mice, Inbred C57BL | NF-kappa B - metabolism | Nanoconjugates | Polyglutamic Acid - analogs & derivatives | Polyglutamic Acid - chemistry | Kidney - metabolism | Animals | Polyglutamic Acid - pharmacology | Janus Kinase 2 - metabolism | Nanomedicine - methods | Chemokine CCL2 - metabolism | Chemokine CCL5 - metabolism | Mice | Active Transport, Cell Nucleus | Kidney Tubules - pathology | Peptoids - chemistry | Apoptosis | Disease Models, Animal | Usage | Kidney diseases | Health aspects | Nanomedicine | Cytochrome | Cell culture | Phosphorylation | Animal models | Nephrology | Transcription | Syngeneic grafts | RANTES | Inflammatory response | Activation | Proteins | Cell activation | Janus kinase 2 | Tumor necrosis factor-TNF | Inhibition | Pharmaceutical sciences | Deoxyribonucleic acid--DNA | Binding | Translocation | NF-κB protein | Antiinflammatory agents | Cytokines | Inflammation | Gene expression | Nuclear transport | Pathology | Chemistry | Apaf-1 protein | Infiltration | Laboratory animals | Chemokines | Monocyte chemoattractant protein 1 | Nanotechnology | Clear cell-type renal cell carcinoma | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e72387
Journal Article
International Urology and Nephrology, ISSN 0301-1623, 4/2014, Volume 46, Issue 4, pp. 765 - 776
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2019, Volume 129, Issue 8, pp. 3293 - 3309
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 09/2018, Volume 10, Issue 9, p. n/a
Senescent cells accumulate in multiple aging‐associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here,... 
senescence | nanomedicine | fibrosis | chemotherapy | palbociclib | CANCER-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | STRESS-INDUCED SENESCENCE | SECRETORY PHENOTYPE | DOXORUBICIN | MESOPOROUS SILICA NANOPARTICLES | CELLULAR SENESCENCE | INHIBITION | IN-VIVO | BETA-GALACTOSIDASE | Piperazines - administration & dosage | Cell Survival - drug effects | Neoplasm Transplantation | Galactose - metabolism | Pyridines - administration & dosage | Cellular Senescence - drug effects | Fluorescent Dyes - metabolism | Lysosomes - enzymology | Cytotoxins - administration & dosage | Oligosaccharides - metabolism | Piperazines - pharmacology | Drug Delivery Systems | Neoplasms - drug therapy | Animals | Cytotoxins - pharmacology | Heterografts | Staining and Labeling | beta-Galactosidase - metabolism | Drug Compounding | Mice | Pyridines - pharmacology | Disease Models, Animal | Drugs | Drug delivery systems | Chemotherapy | Collagen | Analysis | Respiratory tract diseases | Vehicles | Cancer | Encapsulation | Tropism | Thrombocytopenia | Senescence | Respiratory function | Intravenous administration | Therapeutic applications | Tumor cells | Lung diseases | Lysosomes | Cytotoxicity | Drug delivery | Oligosaccharides | Drug development | Doxorubicin | Fluorophores | Fibrosis | Xenografts | Aging | Tumors | Ageing | Pharmacology & Drug Discovery
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2009, Volume 4, Issue 8, p. e6634
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 10/2013, Volume 1832, Issue 10, pp. 1744 - 1755
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) regulates apoptosis, proliferation and inflammation in renal epithelial cells and plays a role in... 
Fn14 | Kidney fibrosis | Proliferation | TWEAK | NFκB | Ras | ACTIVATION | TUBULAR CELL APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROGRESSIVE FIBROSIS | H-RAS | BIOPHYSICS | HORMONE-RELATED PROTEIN | LUPUS NEPHRITIS | INTERSTITIAL FIBROSIS | NF-KAPPA-B | EXPRESSION | NF kappa B | MULTIFUNCTIONAL CYTOKINE | Tumor necrosis factor | Analysis | Fibrosis | Apoptosis
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 05/2008, Volume 19, Issue 5, pp. 904 - 914
Journal Article