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American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 12/2016, Volume 311, Issue 6, pp. H1360 - H1366
Anesthesia can affect respiratory, circulatory, and endocrine systems but is necessary for certain experimental procedures such as echocardiography and blood... 
Ketamine-xylazine | Pentobarbital sodium | Isoflurane | pentobarbital sodium | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | ketamine-xylazine | MECHANISMS | BODY-TEMPERATURE | COMBINATION | BLOOD-PRESSURE | INSULIN | IMPACT | PERIPHERAL VASCULAR DISEASE | MICE | isoflurane | STRESS | HYPERTENSIVE-RATS | Renin - metabolism | Anesthetics, Dissociative - pharmacology | Isoflurane - pharmacology | Pentobarbital - pharmacology | Male | Fatty Acids, Nonesterified - metabolism | Heart Rate - drug effects | Aldosterone - metabolism | Xylazine - pharmacology | Renin - drug effects | Blood Pressure - drug effects | Dopamine - metabolism | Anesthetics, Inhalation - pharmacology | Angiotensin II - drug effects | Echocardiography | Angiotensin II - metabolism | Cholesterol, HDL - drug effects | Cholesterol, HDL - metabolism | Aorta - drug effects | Insulin Resistance | Rats | Cholesterol, LDL - drug effects | Cholesterol - metabolism | Rats, Sprague-Dawley | Triglycerides - metabolism | Blood Glucose - drug effects | Insulin - metabolism | Animals | Norepinephrine - metabolism | Lipid Metabolism - drug effects | Cholesterol, LDL - metabolism | Glucose - metabolism | Renin-Angiotensin System - drug effects | Hemodynamics - drug effects | Hypnotics and Sedatives - pharmacology | Blood Glucose - metabolism | Ketamine - pharmacology | Epinephrine - metabolism | Lipids | Anesthesia | Ultrasonic imaging | Glucose | Metabolism | Rodents | Index Medicus
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 06/2018, Volume 1421, Issue 1, pp. 73 - 87
Melatonin regulates circadian rhythms but also has antioxidative and anti‐inflammatory effects that ameliorate metabolic disorders. We investigated the effects... 
metabolic syndrome | white adipose tissue | brown adipose tissue | melatonin | cardiac remodeling | OXIDATIVE STRESS | 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1 | SPONTANEOUSLY HYPERTENSIVE-RATS | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | VISCERAL ADIPOSITY | BLOOD-PRESSURE | DIASTOLIC DYSFUNCTION | ENERGY-EXPENDITURE | INSULIN-RESISTANCE | DIABETIC FATTY RATS | Heart Injuries - pathology | Heart Injuries - physiopathology | Indenes - pharmacology | Signal Transduction | Heart Injuries - metabolism | Adipose Tissue - pathology | Insulin Resistance | Adipose Tissue, White - metabolism | Rats | Male | Metabolic Syndrome - metabolism | Dose-Response Relationship, Drug | Adipose Tissue - metabolism | Insulin - metabolism | Animals | Indenes - administration & dosage | Adipose Tissue, Brown - metabolism | Oxidative Stress - drug effects | Adipose Tissue - drug effects | Disease Models, Animal | Adipose tissues | Insulin resistance | Body weight | Oxidative stress | Melatonin | Adipose tissue | Body fat | Adipocytes | Dosage | Metabolic syndrome | Proteins | Oxidation resistance | Mitochondria | Uncoupling protein 1 | Animal tissues | Attenuation | Adipose tissue (brown) | Heart diseases | Hypertension | Circadian rhythms | Obesity | Inflammation | Insulin | Body weight gain | Pathology | Signaling | Fibrosis | Ventricle | Metabolic disorders | Hypertrophy
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 8156 - 20
The effects of heat-killed Lactobacillus plantarum L-137 (HK L-137) on chronic inflammation associated with metabolic disorders have remained unknown. We... 
Heart | Spleen | Phosphorylation | Adipose tissue | Body fat | AKT protein | Lymphocytes T | Inflammation | Gene expression | Metabolic syndrome | Insulin | Body weight gain | CD4 antigen | Interleukin 6 | Fibrosis | Sterol regulatory element-binding protein | Ventricle | Heart diseases | Metabolic disorders | Hypertrophy
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 10/2015, Volume 408, Issue 1, pp. 191 - 203
Journal Article
Journal Article
Pharmacology Research & Perspectives, ISSN 2052-1707, 08/2017, Volume 5, Issue 4, pp. e00331 - n/a
The mammalian target of rapamycin (mTOR) is a regulator of metabolism and is implicated in pathological conditions such as obesity and diabetes. We aimed to... 
metabolic syndrome | mammalian target of rapamycin | Adipose tissue | glucose metabolism | cardiac remodeling | Pathology | Obesity | Phosphorylation | Glucose | Metabolic syndrome | Rodents
Journal Article
Journal of Hypertension, ISSN 0263-6352, 10/2018, Volume 36 Suppl 3, pp. e71 - e71
OBJECTIVES:Obesity is associated with increased risk of sudden cardiac death. We previously established the DahlS.Z-Leprfa/Leprfa (DS/obese) rat as an animal... 
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 06/2018, Volume 1421, Issue 1, pp. 73 - 87
Journal Article
Journal Article
International Journal of Cardiology, ISSN 0167-5273, 2017, Volume 240, pp. 332 - 338
Abstract Background Statins are strong inhibitors of cholesterol biosynthesis and help to prevent cardiovascular disease. They also exert additional... 
Cardiovascular | Atorvastatin | Inflammation | Nuclear factor–κB | Metabolic syndrome | AMP-activated protein kinase | Nuclear factor-kappa B | COA REDUCTASE INHIBITOR | CARDIAC & CARDIOVASCULAR SYSTEMS | HEART-FAILURE | ACTIVATED-PROTEIN-KINASE | DIASTOLIC DYSFUNCTION | OBESE MICE | DAHLS.Z-LEPR(FA)/LEPR(FA) RATS | INSULIN-RESISTANCE | ANIMAL-MODEL | NF-KAPPA-B | HYPERTENSIVE-RATS | Inflammation - pathology | Obesity - drug therapy | Atorvastatin Calcium - pharmacology | Oxidative Stress - physiology | Male | Metabolic Syndrome - metabolism | Metabolic Syndrome - drug therapy | Adipose Tissue - metabolism | Inflammation - metabolism | Inflammation - drug therapy | Inflammation Mediators - metabolism | Inflammation Mediators - antagonists & inhibitors | Rats, Inbred Dahl | Atorvastatin Calcium - therapeutic use | Adipose Tissue - pathology | Cells, Cultured | Rats | Random Allocation | Obesity - metabolism | Obesity - pathology | Myocytes, Cardiac - pathology | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Myocytes, Cardiac - drug effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Myocytes, Cardiac - metabolism | Metabolic Syndrome - pathology | Oxidative Stress - drug effects | Adipose Tissue - drug effects | Prevention | Adipose tissues | Cardiovascular agents | Antilipemic agents | Insulin resistance | Protein kinases | Index Medicus
Journal Article
Journal Article
Journal of Hypertension, ISSN 0263-6352, 09/2016, Volume 34 Suppl 1 - ISH 2016 Abstract Book, pp. e205 - e205
OBJECTIVE:The pineal hormone melatonin, which regulates the bodyʼs circadian rhythm, possesses anti-oxidative and anti-inflammatory effects and thereby... 
Journal Article
The Journal of Thoracic and Cardiovascular Surgery, ISSN 0022-5223, 07/2018, Volume 156, Issue 1, pp. 217 - 226.e3
Left ventricular (LV) remodeling alters the contractile and relaxation properties and induces myocardial stiffness. As LV remodeling progresses, the amount of... 
remodeling | ischemic cardiomyopathy | collagen type III | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | INTEGRIN | PEPTIDE SVVYGLR | DILATED CARDIOMYOPATHY | MYOBLAST SHEETS | HEART | ADHESION | IN-VITRO | OSTEOPONTIN | INFARCTION | INTERSTITIUM | RESPIRATORY SYSTEM | Heart | Evaluation | Thrombin | Peptides | Analysis | Collagen | Index Medicus | Abridged Index Medicus
Journal Article
Cardiovascular Research, ISSN 0008-6363, 07/2013, Volume 99, Issue 1, pp. 102 - 110
Transplantation of myoblast sheets is a promising therapy for enhancing cardiac function after heart failure. We have previously demonstrated that a... 
Myocardial infarction | Cell therapy | Myofibroblats | Peptides | Transforming growth factor-β | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | ANGIOGENESIS | Transforming growth factor | IMPAIRED MYOCARDIUM | REGENERATION | HEPATOCYTE GROWTH-FACTOR | TISSUE | OSTEOPONTIN EXPRESSION | CONTRACTILE ACTIVITY | ISCHEMIC CARDIOMYOPATHY | MYOFIBROBLAST DIFFERENTIATION | Genetic Therapy | Ventricular Function, Left | Humans | Actins - metabolism | Heart Failure - physiopathology | Rats, Inbred Lew | Male | Myosin Heavy Chains - metabolism | Recovery of Function | Myofibroblasts - metabolism | Heart Failure - therapy | Ventricular Remodeling | Transfection | Time Factors | Myocardium - metabolism | HEK293 Cells | Smooth Muscle Myosins - metabolism | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Myoblasts, Skeletal - metabolism | Myofibroblasts - pathology | Oligopeptides - genetics | Rats | Heart Failure - genetics | Myocardium - pathology | Heart Failure - metabolism | Heart Failure - pathology | Oligopeptides - biosynthesis | Stroke Volume | Regeneration | Animals | Myoblasts, Skeletal - transplantation | Receptors, Transforming Growth Factor beta - metabolism | Fibrosis | Ventricular Pressure | Smad Proteins - metabolism | Transforming Growth Factor beta - metabolism | Neovascularization, Physiologic | Index Medicus
Journal Article
Journal Article