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Cancer Research, ISSN 0008-5472, 02/2013, Volume 73, Issue 3, pp. 1128 - 1141
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 14, pp. 3834 - 3845
Triple-negative breast cancer (TNBC) patients commonly exhibit poor prognosis and high relapse after treatment, but there remains a lack of biomarkers and... 
BCL-2 | ACTIVATING KINASE | ONCOLOGY | DISEASE | N-MYC | CHRONIC LYMPHOCYTIC-LEUKEMIA | TRANSCRIPTION FACTOR TFIIH | ANTITUMOR-ACTIVITY | INHIBITOR | DNA-BINDING ACTIVITY | P53 | Prognosis | Humans | Middle Aged | RNA, Messenger - metabolism | Triple Negative Breast Neoplasms - drug therapy | Proto-Oncogene Proteins c-bcl-2 - metabolism | bcl-X Protein - antagonists & inhibitors | Aged, 80 and over | Adult | Female | Cyclin-Dependent Kinases - antagonists & inhibitors | Cyclin-Dependent Kinases - genetics | Triple Negative Breast Neoplasms - enzymology | Pyrazoles - pharmacology | Signal Transduction | RNA, Messenger - genetics | Cyclin-Dependent Kinases - biosynthesis | Pyrimidines - pharmacology | Triple Negative Breast Neoplasms - genetics | Cell Line, Tumor | Phenylenediamines - pharmacology | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Aged | Protein Kinase Inhibitors - pharmacology | bcl-X Protein - metabolism | Phosphorylation | Cell survival | Bcl-2 protein | Transcription | Breast cancer | Cyclin-dependent kinase 7 | Gene expression | Ribonucleic acid--RNA | Patients | DNA-directed RNA polymerase | Polymerase | Signaling | Inhibitors | Bcl-x protein | Medical prognosis | Biomarkers | Breast | Bioindicators | Inhibition | RNA polymerase II | Cancer | Apoptosis | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Cancer and Oncology | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article
BMC Medicine, ISSN 1741-7015, 06/2017, Volume 15, Issue 1, pp. 101 - 16
Background: Cutaneous melanoma is the deadliest skin cancer, with an increasing incidence and mortality rate. Currently, staging of patients with primary... 
Molecular markers of metastasis and progression | Correlation of clinical and molecular markers | Molecular diagnosis and prognosis | Melanoma/skin cancers | Tumor staging | CELLS | ACTIVATION | TUMOR PROGRESSION | PROMOTER METHYLATION | TRANSCRIPTION | CANCER | HYPOMETHYLATION | MEDICINE, GENERAL & INTERNAL | GENES | UP-REGULATION | EXPRESSION | Prognosis | DNA, Neoplasm - metabolism | Humans | Middle Aged | Male | Disease Progression | Skin Neoplasms - physiopathology | DNA Methylation | Melanoma - genetics | Skin Neoplasms - genetics | Aged, 80 and over | Adult | Female | Aged | Biomarkers, Tumor - genetics | Melanoma - physiopathology | Melanoma | Development and progression | Diagnosis | Metastasis | Research | Biological markers | Skin cancer | Immunohistochemistry | Genomes | Inactivation | Information dissemination | Incidence | Metastases | Pathways | DNA methylation | Bioindicators | Deoxyribonucleic acid--DNA | Immune system | Defense programs | Deactivation | Feature recognition | Mortality | Markers | Benign | Inflammation | Gene expression | Patients | Adhesion | Studies | Stem cells | Biomarkers | Skin | Genetic testing | Methylation | Differentiation | Chemokines | Tumors | Cancer | Metilació | Càncer de pell | Marcadors tumorals | Tumor markers | DNA | Epigenetics | ADN | Epigenètica | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Cancer and Oncology | Cancer och onkologi
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, pp. e0169964 - e0169964
Sunitinib is a tyrosine kinase inhibitor approved for the treatment of multiple solid tumors. However, cardiotoxicity is of increasing concern, with a need to... 
HEART | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MITOCHONDRIA | TYROSINE KINASE INHIBITOR | CARDIOTOXICITY | CARDIOMYOCYTES | CANCER | MYOCARDIAL-METABOLISM | BLOOD-PRESSURE | ENDOTHELIAL GROWTH-FACTOR | Humans | Ventricular Function, Left - drug effects | Rats | Male | Myocardium - pathology | Positron-Emission Tomography | Rats, Sprague-Dawley | Indoles - administration & dosage | Heart - diagnostic imaging | Animals | Indoles - adverse effects | Pyrroles - administration & dosage | Myocardium - metabolism | Proteomics | Heart - drug effects | Pyrroles - adverse effects | Metabolic Networks and Pathways - drug effects | Fluorodeoxyglucose F18 - therapeutic use | Cell metabolism | Glucose metabolism | Usage | Research | PET imaging | Energy metabolism | Oxidative metabolism | Emission analysis | Glucose | Health physics | Kinases | Remodeling | Signal transduction | Mitochondria | Energy resources | Tomography | Physiology | Oxidation | Blood pressure | Growth factors | Protein-tyrosine kinase | Heart diseases | Adenosine triphosphate | Heart failure | Tyrosine | Medical imaging | Positron emission | Cardiomyocytes | Metabolism | Electron microscopy | Fatty acids | Physics | Substrates | Emissions | Medicine | Signaling | Hospitals | Malate | Perfusion | Glycolysis | Myocardium | Solid tumors | Ventricle | Acetic acid | Positron emission tomography | Tumors | Ejection | Cancer | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 3010 - 3010
Background: Sunitinib is a multi-targeted agent approved for treatment of a number of cancers. However, since approval, data has continually emerged relating... 
Journal Article
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