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1. Full Text Endothelial cell‐derived angiopoietin‐2 is a therapeutic target in treatment‐naive and bevacizumab‐resistant glioblastoma
by Scholz, Alexander and Harter, Patrick N and Cremer, Sebastian and Yalcin, Burak H and Gurnik, Stefanie and Yamaji, Maiko and Di Tacchio, Mariangela and Sommer, Kathleen and Baumgarten, Peter and Bähr, Oliver and Steinbach, Joachim P and Trojan, Jörg and Glas, Martin and Herrlinger, Ulrich and Krex, Dietmar and Meinhardt, Matthias and Weyerbrock, Astrid and Timmer, Marco and Goldbrunner, Roland and Deckert, Martina and Braun, Christian and Schittenhelm, Jens and Frueh, Jochen T and Ullrich, Evelyn and Mittelbronn, Michel and Plate, Karl H and Reiss, Yvonne
EMBO molecular medicine, ISSN 1757-4676, 01/2016, Volume 8, Issue 1, pp. 39 - 57
macrophage polarization | anti‐angiogenic therapy | glioblastoma | tumor angiogenesis | therapy resistance | Tumor angiogenesis | Anti-angiogenic therapy | Therapy resistance | Macrophage polarization | Glioblastoma | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Mannose-Binding Lectins - metabolism | Bevacizumab - therapeutic use | Receptors, Vascular Endothelial Growth Factor - therapeutic use | Recombinant Fusion Proteins - pharmacology | Humans | Receptors, Vascular Endothelial Growth Factor - pharmacology | Recombinant Fusion Proteins - therapeutic use | Brain Neoplasms - pathology | Drug Resistance, Neoplasm | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Angiopoietin-2 - metabolism | Brain - metabolism | Lectins, C-Type - metabolism | Neoplasm Grading | Female | Brain Neoplasms - mortality | Macrophages - immunology | Angiopoietin-2 - blood | Disease Models, Animal | Endothelial Cells - metabolism | Mice, Inbred C57BL | Receptors, Cell Surface - metabolism | Mice, Transgenic | Macrophages - cytology | Brain Neoplasms - drug therapy | Up-Regulation - drug effects | Macrophages - metabolism | Animals | Signal Transduction - drug effects | Endothelial Cells - cytology | Glioblastoma - pathology | Brain - pathology | Mice | Angiopoietin-2 - antagonists & inhibitors | Glioblastoma - drug therapy | Glioblastoma - mortality | Analysis | Permeability | Angiogenesis inhibitors | T cells | Vascular endothelial growth factor | Health aspects | Glioblastoma multiforme | Endothelium | Cell survival | Angiopoietin | Therapeutic applications | Brain cancer | Lymphocytes T | Macrophages | Cancer therapies | Investigations | Endothelial cells | Bevacizumab | Angiogenesis | Genotype & phenotype | Brain research | Rodents | Growth factors | Tumors | Index Medicus | Neuroscience | Pharmacology & Drug Discovery | Cancer
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2. Full Text Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease
by Koch, Philipp and Breuer, Peter and Peitz, Michael and Jungverdorben, Johannes and Kesavan, Jaideep and Poppe, Daniel and Doerr, Jonas and Ladewig, Julia and Mertens, Jerome and Tüting, Thomas and Hoffmann, Per and Klockgether, Thomas and Evert, Bernd O and Wüllner, Ullrich and Brüstle, Oliver
Nature (London), ISSN 0028-0836, 12/2011, Volume 480, Issue 7378, pp. 543 - 546
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neurology | Biological and medical sciences | Medical sciences | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Calpain - metabolism | Ataxin-3 | Glutamic Acid - pharmacology | Calcium - metabolism | Excitatory Amino Acids - pharmacology | Humans | Cells, Cultured | Nuclear Proteins - metabolism | Nerve Tissue Proteins - metabolism | Neurons - metabolism | Neurons - drug effects | Repressor Proteins - metabolism | Machado-Joseph Disease - pathology | Physiological aspects | Genetic engineering | Research | Cerebellar ataxia | Index Medicus
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3. Full Text Strategic development of business models: Implications of the web 2.0 for creating value on the internet
by Wirtz, Bernd W and Schilke, Oliver and Ullrich, Sebastian
Long range planning, ISSN 0024-6301, 04/2010, Volume 43, Issue 2-3, pp. 272 - 290
Development Studies | Business & Economics | Social Sciences | Management | Business | Technology adoption | Studies | Strategic management | Internet | Business models
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4. Full Text The discovery of receptor tyrosine kinases: targets for cancer therapy
by Gschwind, Andreas and Fischer, Oliver M and Ullrich, Axel
Nature reviews. Cancer, ISSN 1474-175X, 05/2004, Volume 4, Issue 5, pp. 361 - 370
Antineoplastic Agents - history | Animals | Receptor Protein-Tyrosine Kinases - history | History, 20th Century | Humans | Care and treatment | Physiological aspects | Protein tyrosine kinase | Cellular signal transduction | Genetic aspects | Research | Health aspects | Methods | Cancer | Index Medicus
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5. Full Text Resolution dependence of precipitation statistical fidelity in hindcast simulations
by O'Brien, Travis A and Collins, William D and Kashinath, Karthik and Rübel, Oliver and Byna, Suren and Gu, Junmin and Krishnan, Hari and Ullrich, Paul A and Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Journal of advances in modeling earth systems, ISSN 1942-2466, 06/2016, Volume 8, Issue 2, pp. 976 - 990
updraft | precipitation | hindcast | resolution | extremes | CAM | Meteorology & Atmospheric Sciences | Physical Sciences | Science & Technology | Precipitation | Dependence | Statistical analysis | General circulation models | Atmospheric models | Ocean circulation | Duration | Climate models | Weather extremes | Physics | Earth | Simulation | Archives & records | Experimental design | Rainfall intensity | Scaling | Resolution | ENVIRONMENTAL SCIENCES
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6. Full Text Drug repositioning of antiretroviral ritonavir for combinatorial therapy in glioblastoma
by Rauschenbach, Laurèl and Wieland, Anja and Reinartz, Roman and Kebir, Sied and Till, Andreas and Darkwah Oppong, Marvin and Dobersalske, Celia and Ullrich, Vivien and Ahmad, Ashar and Jabbarli, Ramazan and Pierscianek, Daniela and Fröhlich, Holger and Simon, Matthias and Brüstle, Oliver and Sure, Ulrich and Glas, Martin and Scheffler, Björn
European journal of cancer (1990), ISSN 0959-8049, 11/2020, Volume 140, pp. 130 - 139
Temozolomide | Repositioning | Ritonavir | Autophagy | Glioblastoma | Life Sciences & Biomedicine | Oncology | Science & Technology | Protease inhibitors | Proteases | Health aspects | Glioblastoma multiforme | Analysis | Brain tumors | Xenotransplantation | Radiation | Viruses | Proteinase inhibitors | Tumor cell lines | Anticancer properties | Antiretroviral agents | Human immunodeficiency virus--HIV | Xenografts | Irradiation | In vivo methods and tests | Endoplasmic reticulum | Combinatorial analysis | Phagocytosis | Index Medicus
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7. Full Text DNA methylation in Parkinson's disease
by Wüllner, Ullrich and Kaut, Oliver and deBoni, Laura and Piston, Dominik and Schmitt, Ina
Journal of neurochemistry, ISSN 0022-3042, 10/2016, Volume 139, Issue S1, pp. 108 - 120
DNA methylation | alpha‐synuclein | aging | neurons | expression regulation | epigenetics | Aging | Epigenetics | Neurons | Alpha-synuclein | Expression regulation | Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Humans | Ubiquitin-Protein Ligases - metabolism | Parkinson Disease - genetics | Epigenesis, Genetic - physiology | Animals | Aging - genetics | Parkinson Disease - diagnosis | Parkinson Disease - metabolism | alpha-Synuclein - genetics | DNA Methylation - physiology | Ubiquitin-Protein Ligases - genetics | alpha-Synuclein - metabolism | Aging - metabolism | Epigenetic inheritance | Embryonic development | Parkinson's disease | Prader-Willi syndrome | Genes | DNA | Genetic research | Nucleotide sequencing | Genetic transcription | Methylation | Mental illness | DNA sequencing | Deoxyribonucleic acid--DNA | Parkinsons disease | Index Medicus
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