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Nature Chemistry, ISSN 1755-4330, 07/2015, Volume 7, Issue 7, pp. 538 - 539
Journal Article
Nature Chemistry, ISSN 1755-4330, 06/2015, Volume 7, Issue 7, pp. 538 - 539
Journal Article
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 11/2018, Volume 24, Issue 63, p. n/a
Systemic side effects limit the efficacy of chemotherapy regimens. To reduce toxicity, a metabolically stable prodrug of SN‐38 (irinotecan's active metabolite)... 
combination therapy | palladium | bioorthogonal catalysis | irinotecan | anticancer drugs | Metabolites | Palladium | Irinotecan | Side effects | Chemotherapy | Vitamin D | Toxicity | Tumors
Journal Article
Nature Chemistry, ISSN 1755-4330, 03/2011, Volume 3, Issue 3, pp. 239 - 243
Many important intracellular biochemical reactions are modulated by transition metals, typically in the form of metalloproteins. The ability to carry out... 
Humans | Metal Nanoparticles - chemistry | Catalysis | HeLa Cells | Palladium - chemistry | Carbamates - chemistry | Polystyrenes - chemistry | Index Medicus
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 10/2017, Volume 56, Issue 41, pp. 12789 - 12789
Thiols are ubiquitous in living systems where they bind strongly to gold surfaces and render interactions with other functional groups basically non‐existent.... 
gold | bioorthogonal | heterogeneous catalysis | prodrugs | fluorescent probes | Drugs | Gold | Cell culture | Thiols | Antitumor agents | Catalysts | Zebrafish | Functional groups | Cancer
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 04/2016, Volume 59, Issue 8, pp. 3593 - 3608
Journal Article
Nature protocols, ISSN 1754-2189, 2012, Volume 7, Issue 6, pp. 1207 - 1218
We have developed miniaturized heterogeneous Pd(0)-catalysts (Pd(0)-microspheres) with the ability to enter cells, stay harmlessly within the cytosol and... 
Microspheres | Polystyrenes - chemical synthesis | Biochemistry - methods | Humans | Metal Nanoparticles - chemistry | HeLa Cells | Microscopy, Electron | Palladium - chemistry | Polystyrenes - chemistry | Cytosol - chemistry | Index Medicus
Journal Article
Magnetic Resonance in Chemistry, ISSN 0749-1581, 09/2018, Volume 56, Issue 9, pp. 852 - 859
Journal Article
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 09/2018, Volume 29, Issue 9, pp. 3154 - 3160
Chemical proteomics approaches are widely used to identify molecular targets of existing or novel drugs. This manuscript describes the development of a... 
Drugs | Target recognition | Fluorescence | Kinases | Src protein | Drug development | Nanoparticles | Proteins | Organic chemistry | Cycloaddition | Proteomics | Conjugation | Copper | Chemical synthesis | Alkynes | Cancer
Journal Article
Journal Article
Future Medicinal Chemistry, ISSN 1756-8919, 01/2019, Volume 11, Issue 2, pp. 83 - 95
Aim: Identification of new antiproliferative compounds. Methodology: Four series of compounds were synthesized by the Mitsunobu reaction. Their... 
apoptosis | benzoxazine | quinoline | Mitsunobu | antiproliferative activity | pyridoxazine | PATHWAYS | ANTICANCER ACTIVITY | CHEMISTRY, MEDICINAL | EFFICIENT | MUTAGENICITY
Journal Article
ISSN 2041-6520, 9/2018, Volume 9, Issue 37, pp. 7354 - 7361
The incorporation of transition metal catalysts to the bioorthogonal toolbox has opened the possibility of producing supra-stoichiometric amounts of... 
Journal Article
MedChemComm, ISSN 2040-2503, 3/2016, Volume 7, Issue 3, pp. 562 - 562
Correction for ' eCF309 : a potent, selective and cell-permeable mTOR inhibitor' by Craig Fraser et al. , MedChemComm , 2016, DOI: 10.1039/c5md00493d. 
Journal Article
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