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1. Full Text Methylmercury, an environmental electrophile capable of activation and disruption of the Akt/CREB/Bcl-2 signal transduction pathway in SH-SY5Y cells
by Unoki, Takamitsu and Abiko, Yumi and Toyama, Takashi and Uehara, Takashi and Tsuboi, Koji and Nishida, Motohiro and Kaji, Toshiyuki and Kumagai, Yoshito
Scientific reports, ISSN 2045-2322, 06/2016, Volume 6, Issue 1, pp. 28944 - 28944
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Index Medicus
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2. Full Text SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
by Takahashi, Atsushi and Lauritzen, Torsten and Kamatani, Naoyuki and Kadowaki, Takashi and Holmkvist, Johan and Nurbaya, Siti and Sandbæk, Annelli and Tai, E Shyong and Borch-Johnsen, Knut and Unoki, Hiroyuki and Nakamura, Yusuke and Ng, Daniel P K and Kashiwagi, Atsunori and Maeda, Shiro and Horikoshi, Momoko and Kikkawa, Ryuichi and Hansen, Torben and Hirose, Hiroshi and Andersen, Gitte and Babazono, Tetsuya and Hayashi, Matsuhiko and Tsunoda, Tatsuhiko and Iwamoto, Yasuhiko and Kawaguchi, Takahisa and Kubo, Michiaki and Jørgensen, Torben and Kaku, Kohei and Kawamori, Ryuzo and Pedersen, Oluf and Hara, Kazuo
Nature genetics, ISSN 1061-4036, 09/2008, Volume 40, Issue 9, pp. 1098 - 1102
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Diabetes. Impaired glucose tolerance | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Endocrine pancreas. Apud cells (diseases) | European Continental Ancestry Group - genetics | Gene Expression | Genetic Predisposition to Disease | Genome-Wide Association Study | KCNQ1 Potassium Channel - genetics | Singapore | Diabetes Mellitus, Type 2 - genetics | Humans | Asian Continental Ancestry Group - genetics | Polymorphism, Single Nucleotide | Case-Control Studies | Type 2 diabetes | Causes of | Disease susceptibility | Genetic aspects | Single nucleotide polymorphisms | Research | Health aspects | Risk factors | Studies | Medical research | Diabetic retinopathy | Genomics | Cyclin-dependent kinases | Population | Statistical methods | Regression analysis | Genetic testing | Diabetes | Index Medicus
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3. Full Text Polysulfide Na2S4 regulates the activation of PTEN/Akt/CREB signaling and cytotoxicity mediated by 1,4-naphthoquinone through formation of sulfur adducts
by Abiko, Yumi and Shinkai, Yasuhiro and Unoki, Takamitsu and Hirose, Reiko and Uehara, Takashi and Kumagai, Yoshito
Scientific reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 1 - 11
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein kinase A | Tensin | Phosphorylation | Transcription factors | Thiols | Cytotoxicity | AKT protein | Cyclic AMP response element-binding protein | Kinases | Proteins | Signal transduction | Hepatocytes | Cell death | Sulfur | PTEN protein | Adducts | Index Medicus
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4. Full Text Characterization of genetic‐origin‐dependent monoallelic expression in mouse embryonic stem cells
by Ohishi, Hiroaki and Au Yeung, Wan Kin and Unoki, Motoko and Ichiyanagi, Kenji and Fukuda, Kei and Maenohara, Shoji and Shirane, Kenjiro and Chiba, Hatsune and Sado, Takashi and Sasaki, Hiroyuki
Genes to cells : devoted to molecular & cellular mechanisms, ISSN 1356-9597, 01/2020, Volume 25, Issue 1, pp. 54 - 64
histone methylation | transcription factor binding site | embryonic stem cell | monoallelically expressed gene | retrotransposon | single nucleotide polymorphism | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Embryo cells | Stem cell transplantation | Blastocysts | Single-nucleotide polymorphism | Regulatory sequences | Genetic diversity | Gene expression | Mammalian cells | Stem cells | DNA methylation | Epigenetics | Pluripotency | CpG islands | Index Medicus
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5. Full Text The GCN5-CITED2-PKA signalling module controls hepatic glucose metabolism through a cAMP-induced substrate switch
by Sakai, Mashito and Tujimura-Hayakawa, Tomoko and Yagi, Takashi and Yano, Hiroyuki and Mitsushima, Masaru and Unoki-Kubota, Hiroyuki and Kaburagi, Yasushi and Inoue, Hiroshi and Kido, Yoshiaki and Kasuga, Masato and Matsumoto, Michihiro
Nature communications, ISSN 2041-1723, 11/2016, Volume 7, Issue 1, pp. 13147 - 13147
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cyclic AMP-Dependent Protein Kinases - metabolism | Cell Line | Signal Transduction | Humans | Liver - metabolism | Mice, Inbred C57BL | Cells, Cultured | Diet, High-Fat - adverse effects | Repressor Proteins - genetics | Male | Gene Expression Regulation - drug effects | Gluconeogenesis - physiology | p300-CBP Transcription Factors - metabolism | Animals | Cyclic AMP-Dependent Protein Kinases - genetics | p300-CBP Transcription Factors - genetics | Trans-Activators - genetics | Glucose - metabolism | Trans-Activators - metabolism | Mice | Diabetes Mellitus, Type 2 - chemically induced | Cyclic AMP - metabolism | Hepatocytes - physiology | Repressor Proteins - metabolism | Index Medicus
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6. Full Text Serine 298 Phosphorylation in Linker 2 of UHRF1 Regulates Ligand-Binding Property of Its Tandem Tudor Domain
by Kori, Satomi and Jimenji, Tomohiro and Ekimoto, Toru and Sato, Miwa and Kusano, Fumie and Oda, Takashi and Unoki, Motoko and Ikeguchi, Mitsunori and Arita, Kyohei
Journal of molecular biology, ISSN 0022-2836, 06/2020, Volume 432, Issue 14, pp. 4061 - 4075
DNA methylation | molecular dynamics | small-angle X-ray scattering (SAXS) | phosphorylation | isothermal titration calorimetry (ITC) | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Binding - genetics | Humans | Tudor Domain - genetics | Scattering, Small Angle | Serine - genetics | DNA Methylation - genetics | DNA, Intergenic - genetics | Molecular Dynamics Simulation | Phosphorylation - genetics | Histones - genetics | Epigenesis, Genetic - genetics | DNA Replication - genetics | Ligands | CCAAT-Enhancer-Binding Proteins - genetics | Ubiquitin-Protein Ligases - genetics | Molecular dynamics | DNA replication | Methylation | Ligases | Protein binding | Index Medicus
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7. Full Text Incidence and predictors of ischemic stroke during hospitalization for congestive heart failure
by Hamatani, Yasuhiro and Hamatani, Yasuhiro and Iguchi, Moritake and Iguchi, Moritake and Nakamura, Michikazu and Nakamura, Michikazu and Ohtani, Ryo and Ohtani, Ryo and Yamashita, Yugo and Yamashita, Yugo and Takagi, Daisuke and Takagi, Daisuke and Unoki, Takashi and Unoki, Takashi and Ishii, Mitsuru and Ishii, Mitsuru and Masunaga, Nobutoyo and Masunaga, Nobutoyo and Ogawa, Hisashi and Ogawa, Hisashi and Hamatani, Mio and Hamatani, Mio and Abe, Mitsuru and Abe, Mitsuru and Akao, Masaharu and Akao, Masaharu
Heart and vessels, ISSN 0910-8327, 7/2016, Volume 31, Issue 7, pp. 1154 - 1161
Biomedical Engineering | Heart failure | Medicine & Public Health | Cardiac Surgery | Vascular Surgery | Hospitalization | Ischemic stroke | Cardiology | Predictors | Cardiac & Cardiovascular Systems | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Japan - epidemiology | Anticoagulants - administration & dosage | Blood Urea Nitrogen | Humans | Middle Aged | Stroke - diagnosis | Male | Heart Failure - blood | Incidence | Heart Failure - therapy | Brain Ischemia - blood | Time Factors | Aged, 80 and over | Female | Stroke - epidemiology | Heart Failure - diagnosis | Retrospective Studies | Atrial Fibrillation - diagnosis | Odds Ratio | Heart Failure - epidemiology | Brain Ischemia - epidemiology | Administration, Oral | Atrial Fibrillation - drug therapy | Risk Factors | Kaplan-Meier Estimate | Biomarkers - blood | Chi-Square Distribution | Stroke - blood | Atrial Fibrillation - epidemiology | Brain Ischemia - diagnosis | Aged | Stroke (Disease) | Urea | Ischemia | Atrial fibrillation | Cardiac patients | Endocarditis | Anticoagulants (Medicine) | Congestive heart failure | Heart attack | Stroke | Epidemiology | Risk factors | Index Medicus
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8. Full Text Incidence and Risk Factors of Stroke or Systemic Embolism in Patients With Atrial Fibrillation and Heart Failure　― The Fushimi AF Registry
by Iguchi, Moritake and Tezuka, Yuji and Ogawa, Hisashi and Hamatani, Yasuhiro and Takagi, Daisuke and An, Yoshimori and Unoki, Takashi and Ishii, Mitsuru and Masunaga, Nobutoyo and Esato, Masahiro and Tsuji, Hikari and Wada, Hiromichi and Hasegawa, Koji and Abe, Mitsuru and Lip, Gregory Y.H and Akao, Masaharu
Circulation journal : official journal of the Japanese Circulation Society, ISSN 1346-9843, 2018, Volume 82, Issue 5, pp. 1327 - 1335
Heart failure | Stroke | Decompensated heart failure | Atrial fibrillation | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology
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9. Full Text PHD3 regulates glucose metabolism by suppressing stress-induced signalling and optimising gluconeogenesis and insulin signalling in hepatocytes
by Yano, Hiroyuki and Sakai, Mashito and Matsukawa, Toshiya and Yagi, Takashi and Naganuma, Takao and Mitsushima, Masaru and Iida, Satoshi and Inaba, Yuka and Inoue, Hiroshi and Unoki-Kubota, Hiroyuki and Kaburagi, Yasushi and Asahara, Shun-ichiro and Kido, Yoshiaki and Minami, Shiro and Kasuga, Masato and Matsumoto, Michihiro
Scientific reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 14290 - 16
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Protein kinase A | Transcription | Glucagon | Diabetes mellitus | Liver | Homeostasis | Proline | Event-related potentials | Glucose | Metabolism | Cyclic AMP response element-binding protein | Kinases | Insulin | Proteins | Glucose metabolism | Signal transduction | Hepatocytes | Prolyl hydroxylase | Diabetes mellitus (non-insulin dependent) | Procollagen-proline dioxygenase | Gluconeogenesis | Index Medicus
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10. Full Text How Successful Is Parenteral Oxycodone for Relieving Terminal Cancer Dyspnea Compared With Morphine? A Multicenter Prospective Observational Study
by Mori, Masanori and Kawaguchi, Takashi and Imai, Kengo and Yokomichi, Naosuke and Yamaguchi, Takashi and Suzuki, Kozue and Matsunuma, Ryo and Watanabe, Hiroaki and Maeda, Isseki and Uehara, Yuko and Morita, Tatsuya and EASED Investigators
Journal of pain and symptom management, 12/2020
Index Medicus
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