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Circulation Research, ISSN 0009-7330, 04/2019, Volume 124, Issue 9, pp. e81 - e81
Journal Article
Heart, ISSN 1355-6037, 05/2019, Volume 105, Issue Suppl 6, p. A167
IntroductionPulmonary arterial hypertension (PAH) is a life-threatening disease characterized by progressive vasoconstriction, vascular remodelling, and... 
Proteins | Cytokines | Pulmonary arteries | Nitric oxide | Gene expression | Veins & arteries | Apoptosis
Journal Article
EXPERIMENTAL PHYSIOLOGY, ISSN 0958-0670, 08/2013, Volume 98, Issue 8, pp. 1262 - 1266
Germ-line mutations in the bone morphogenetic protein type II receptor (BMPR2; BMPR-II) gene, a transforming growth factor- (TGF) receptor superfamily member,... 
PHYSIOLOGY | TGF-BETA | ARTERIAL-HYPERTENSION | SUSCEPTIBILITY | RECEPTOR | MONOCROTALINE | SMOOTH-MUSCLE-CELLS | MICE | PROLIFERATION | EXPRESSION | PROGRESSION | Bone morphogenetic proteins | Endothelin | Transforming growth factors | Analysis | Pulmonary hypertension
Journal Article
Nature Medicine, ISSN 1078-8956, 07/2015, Volume 21, Issue 7, pp. 777 - 785
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1416 - 16
Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious variation within components of the transforming growth factor-beta... 
SOX17 | GENE | ANGIOGENESIS | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | BMP9 | ASSOCIATION | EXPRESSION | NONSENSE MUTATION | BETA-RECEPTOR | CAVEOLIN-1 | Prognosis | Humans | Male | Familial Primary Pulmonary Hypertension - diagnosis | SOXF Transcription Factors - metabolism | Aquaporin 1 - metabolism | Case-Control Studies | Familial Primary Pulmonary Hypertension - metabolism | Membrane Transport Proteins - genetics | Base Sequence | HEK293 Cells | Adult | Female | Growth Differentiation Factors - genetics | Membrane Transport Proteins - metabolism | Familial Primary Pulmonary Hypertension - pathology | Genetic Predisposition to Disease | Bone Morphogenetic Protein Receptors, Type II - genetics | Signal Transduction | Gene Expression Regulation | Adenosine Triphosphatases - metabolism | Models, Molecular | Familial Primary Pulmonary Hypertension - genetics | Bone Morphogenetic Protein Receptors, Type II - metabolism | Membrane Transport Proteins - chemistry | Whole Genome Sequencing | Aquaporin 1 - chemistry | Aquaporin 1 - genetics | Growth Differentiation Factors - metabolism | Transforming Growth Factor beta - genetics | Adenosine Triphosphatases - chemistry | Adenosine Triphosphatases - genetics | Mutation | SOXF Transcription Factors - genetics | Transforming Growth Factor beta - metabolism | SOXF Transcription Factors - chemistry | Growth Differentiation Factors - chemistry | Hypertension | Bone morphogenetic protein receptor type II | Secretion | Transforming growth factor | Genes | Genomes | Heritability | Aquaporin 1 | Gene sequencing
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2
Fig 1B: thumbnail Download: * PPT PowerPoint slide * PNG larger image * TIFF original image Fig 8A: thumbnail Download: * PPT PowerPoint slide * PNG larger... 
Bone morphogenetic proteins | Endothelin 1 | Endothelin | Leukocyte migration | Cell migration | Endothelial cells
Journal Article
Experimental Physiology, ISSN 0958-0670, 08/2013, Volume 98, Issue 8, pp. 1262 - 1266
Journal Article
Journal Article
CIRCULATION RESEARCH, ISSN 0009-7330, 04/2019, Volume 124, Issue 9, pp. E81 - E81
Journal Article
Journal Article
American Journal of Human Genetics, ISSN 0002-9297, 09/2013, Volume 93, Issue 3, p. 530
  Hereditary hemorrhagic telangiectasia (HHT), the most common inherited vascular disorder, is caused by mutations in genes involved in the transforming growth... 
Proteins | Angiogenesis | Genotype & phenotype | Zebrafish | Mutation | Hemorrhage
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 12/2013, Volume 49, Issue 6, pp. 1135 - 1145
Previous studies of pulmonary arterial hypertension (PAH) have implicated excessive transforming growth factor (TGF)-β 1 signaling and reduced bone... 
Pulmonary arterial hypertension | Bone morphogenetic protein | Transforming growth factor beta | Inhibitor of differentiation | transforming growth factor beta | pulmonary arterial hypertension | bone morphogenetic protein | inhibitor of differentiation
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 02/2009, Volume 119, Issue 4, pp. 566 - 576
Background-Recent genetic studies have highlighted the role of the bone morphogenetic protein (BMP)/transforming growth factor (TGF)-beta signaling pathways in... 
Pathology | Hypoxia | Hemodynamics | Vessels | Hypertension, pulmonary | FIBROSIS | hypoxia | CARDIAC & CARDIOVASCULAR SYSTEMS | pathology | BMPR2 | hypertension, pulmonary | SMOOTH | PROLIFERATION | MUSCLE-CELLS | hemodynamics | FEATURES | ARTERIAL-HYPERTENSION | II RECEPTOR | PERIPHERAL VASCULAR DISEASE | MUTATIONS | vessels | Monocrotaline | Male | RNA, Messenger - metabolism | Hypertension, Pulmonary - chemically induced | Cell Movement - physiology | Quinolines - pharmacology | Hypoxia - metabolism | Bone Morphogenetic Proteins - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Benzamides - pharmacology | Hypertension, Pulmonary - drug therapy | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Bone Morphogenetic Protein Receptors, Type II - genetics | Rats | Hypertension, Pulmonary - metabolism | Rats, Sprague-Dawley | Bone Morphogenetic Protein Receptors, Type II - metabolism | Disease Progression | Cell Movement - drug effects | Muscle, Smooth, Vascular - pathology | Animals | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Hypoxia - pathology | Signal Transduction - physiology | Chronic Disease | Muscle, Smooth, Vascular - enzymology | Transforming Growth Factor beta - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 03/2012, Volume 302, Issue 6, pp. L604 - L615
Journal Article