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by Dennis, Martin and Cranswick, G and Fraser, A and Graham, C and Grant, S and Gunkel, A and Hunter, J and MacRae, A and Perry, D and Williamson, A and Dennis, M and Sandercock, P.A.G and Graham, C and Murray, G and Venables, G and Bowler, G and Cranswick, G and Dennis, M and Graham, C and Lewis, S and Murray, G and Reid, J and Rudd, A and Sandercock, P.A.G and Venables, G and Celani, M.G and Ricci, S and Lindley, R and Hautvast, M and Paterson, M and Reid, J and Bamford, J and Lindley, R and Romerosa, M and Royan, A and Russell, M and Boers, P and Claxton, A and Hankey, G and Gubitz, G and Jarrett, J and Legg, K and MacKay, M and Nearing, S and Phillips, S and Ehler, E and Geier, P and Mrklovský, M and Anandan, A.M and Rosario, J and Roy, A.K and Duff, C and Masterson, L and Morris, J and Crowe, M and Noone, I and Fancello, M.A and Parish, L.D and Pileri, P and Pinna, M and Scodino, C and Zedde, M.L and Bondo, V and Capecchi, D and Celani, M.G and Cupella, S and Macchitella, A and Ottaviani, C and Righetti, E and Rossi, C and Tufi, A and Barilaro, A and Dioguardi, S and Gallinella, E and Greco, L and Mattioni, A and Mazzoli, T and Ricci, S and Procaccianti, G and Beccu, P and Musselli, M.A and Traccis, S and Grasselli, G.S and Rasura, M and Chiarandini, S and Chiodo Grandi, F and Zugna, L and Stefanucci, S and Canhão, P and Melo, T.P and Eadie, E and Keir, S and Smith, L and Taylor, P and Thomas, A and Wardlaw, J and Anthony, J and Boynes, A and Clough, R and Colabella, C and ... and unav and The CLOTS Trials Collaboration and CLOTS Trials Collaboration
The Lancet (British edition), ISSN 0140-6736, 2009, Volume 373, Issue 9679, pp. 1958 - 1965
Journal Article
Advances in therapy, ISSN 1865-8652, 2015, Volume 32, Issue 8, pp. 742 - 756
...) have a considerable impact on patients' quality of life and healthcare budgets. Biosimilar infliximab (Remsima(A (R... 
Remicade | Psoriasis | Rheumatology | Internal Medicine | Oncology | Remsima | Biosimilar | Psoriatic arthritis | Medicine & Public Health | Infliximab | Rheumatoid arthritis | Cardiology | Pharmacology/Toxicology | Endocrinology | Ankylosing spondylitis | Crohn’s disease | Ulcerative colitis | MEDICINE, RESEARCH & EXPERIMENTAL | Remicade (R) | COST-EFFECTIVENESS | INNOVATOR INFLIXIMAB | CROHNS-DISEASE | ACTIVE RHEUMATOID-ARTHRITIS | Crohn's disease | ANKYLOSING-SPONDYLITIS | PSORIATIC-ARTHRITIS | PARALLEL-GROUP | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | Remsima (R) | QUALITY-OF-LIFE | NECROSIS-FACTOR INHIBITORS | Arthritis, Psoriatic - economics | Models, Econometric | Biosimilar Pharmaceuticals - therapeutic use | Europe | Humans | Spondylitis, Ankylosing - drug therapy | Infliximab - economics | Antibodies, Monoclonal - therapeutic use | Male | Biosimilar Pharmaceuticals - economics | Infliximab - therapeutic use | Spondylitis, Ankylosing - economics | Drug Costs - statistics & numerical data | Arthritis, Rheumatoid - drug therapy | Arthritis, Psoriatic - drug therapy | Antirheumatic Agents - economics | Female | Aged | Antibodies, Monoclonal - economics | Arthritis, Rheumatoid - economics | Cost Savings - statistics & numerical data | Prescription Fees - statistics & numerical data | Cost Savings - methods | Antirheumatic Agents - therapeutic use | Rheumatoid factor | Care and treatment | Analysis | Resveratrol | Budget | Autoimmune diseases | Original Research
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CPT: Pharmacometrics & Systems Pharmacology, ISSN 2163-8306, 03/2015, Volume 4, Issue 3, pp. 146 - 159
Interactive applications, developed using Shiny for the R programming language, have the potential to revolutionize the sharing and communication of pharmacometric model simulations... 
Data analysis | Language | Audiences | Population | Software | Nonsteroidal anti-inflammatory drugs | Internet | Tutorial
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 2015, Volume 522, Issue 7556, pp. 315 - 320
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 1416 - 16
Pulmonary arterial hypertension (PAH) is a rare disorder with a poor prognosis. Deleterious variation within components of the transforming growth factor-beta... 
a_open_article_in_open_journal | SOX17 | GENE | ANGIOGENESIS | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | BMP9 | ASSOCIATION | EXPRESSION | NONSENSE MUTATION | BETA-RECEPTOR | CAVEOLIN-1 | Prognosis | Humans | Male | Familial Primary Pulmonary Hypertension - diagnosis | SOXF Transcription Factors - metabolism | Aquaporin 1 - metabolism | Case-Control Studies | Familial Primary Pulmonary Hypertension - metabolism | Membrane Transport Proteins - genetics | Base Sequence | HEK293 Cells | Adult | Female | Growth Differentiation Factors - genetics | Membrane Transport Proteins - metabolism | Familial Primary Pulmonary Hypertension - pathology | Genetic Predisposition to Disease | Bone Morphogenetic Protein Receptors, Type II - genetics | Signal Transduction | Gene Expression Regulation | Adenosine Triphosphatases - metabolism | Models, Molecular | Familial Primary Pulmonary Hypertension - genetics | Bone Morphogenetic Protein Receptors, Type II - metabolism | Membrane Transport Proteins - chemistry | Whole Genome Sequencing | Aquaporin 1 - chemistry | Aquaporin 1 - genetics | Growth Differentiation Factors - metabolism | Transforming Growth Factor beta - genetics | Adenosine Triphosphatases - chemistry | Adenosine Triphosphatases - genetics | Mutation | SOXF Transcription Factors - genetics | Transforming Growth Factor beta - metabolism | SOXF Transcription Factors - chemistry | Growth Differentiation Factors - chemistry | Hypertension | Bone morphogenetic protein receptor type II | Secretion | Transforming growth factor | Genes | Genomes | Heritability | Aquaporin 1 | Pulmonary hypertension | Gene sequencing
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CPT: pharmacometrics and systems pharmacology, ISSN 2163-8306, 2013, Volume 2, Issue 4, pp. e38 - 14
Population pharmacokinetic models are used to describe the time course of drug exposure in patients and to investigate sources of variability in patient... 
Datasets | Plasma | Economic models | Pediatrics | Parameter estimation | Databases | Software | Drug dosages | Methods | Tutorial
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