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The New England Journal of Medicine, ISSN 0028-4793, 08/2010, Volume 363, Issue 8, pp. 711 - 723
Journal Article
New England Journal of Medicine, ISSN 0028-4793, 11/2011, Volume 365, Issue 20, p. 1939
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2017, Volume 23, Issue 20, pp. 6165 - 6177
Purpose: Antibodies specific for inhibitory checkpoints PD-1 and CTLA-4 have shown impressive results against solid tumors. This has fueled interest in novel... 
ONCOLOGY | THERAPEUTIC-EFFICACY | IMMUNE-RESPONSES | POOR-PROGNOSIS | CD4(+) T-CELLS | COSTIMULATORY MOLECULE | ESTABLISHED MELANOMA | OVARIAN-CANCER | HUMAN BREAST-CANCER | LYMPHOPENIC HOSTS | ANTITUMOR EFFICACY | T-Lymphocyte Subsets - immunology | Immunotherapy - methods | Humans | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Receptors, OX40 - metabolism | Time Factors | T-Lymphocyte Subsets - drug effects | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Molecular Targeted Therapy - methods | Cytokines - blood | Disease Models, Animal | Cytokines - metabolism | Receptors, Antigen, T-Cell - metabolism | Programmed Cell Death 1 Receptor - metabolism | Immunophenotyping | Mice, Transgenic | Survival Rate | Treatment Outcome | Lymphocytes, Tumor-Infiltrating - drug effects | Antineoplastic Agents, Immunological - pharmacology | Xenograft Model Antitumor Assays | Animals | Antineoplastic Agents, Immunological - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | T-Lymphocyte Subsets - metabolism | Lymphocyte Count | Mice | Lymphocytes, Tumor-Infiltrating - immunology | Receptors, OX40 - antagonists & inhibitors | Cell proliferation | Animal models | PD-1 protein | CD8 antigen | Clinical trials | Antibodies | Lymphocytes T | Contraction | Anticancer properties | Receptors | CTLA-4 protein | Cell activation | Cell growth | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Immunotherapy | Medical research | Cytokines | T cell receptors | CD4 antigen | Immune checkpoint | Experimental design | Tumor necrosis factor | Exhaustion | Antitumor activity | Solid tumors | Tumors | Cancer | Combination immunotherapy | T cells | Costimulation | Checkpoint blockade
Journal Article
Journal Article
Cell, ISSN 0092-8674, 11/2017, Volume 171, Issue 4, pp. 934 - 949.e16
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2017, Volume 377, Issue 26, pp. 2593 - 2596
Journal Article
New England Journal of Medicine, ISSN 0028-4793, 12/2010, Volume 363, Issue 23, pp. 2262 - 2263
Journal Article
Cancer Research, ISSN 0008-5472, 12/2013, Volume 73, Issue 24, pp. 7189 - 7198
Journal Article
by Jayasinghe, Reyka G and Cao, Song and Gao, Qingsong and Gao, Jianjiong and Gao, Galen F and Wendl, Michael C and Vo, Nam Sy and Reynolds, Sheila and Reynolds, Sheila M and Zhao, Fengmei and Zhao, Yanyan and Climente-González, Héctor and Chai, Shengjie and Wang, Zhining and Wang, Fang and Wang, Min and Wang, Jing and Wang, Timothy and Wang, Linghua and Wang, Jioajiao and Varghese, Rajees and Huang, Mo and Liang, Wen-Wei and Liang, Han and Wyczalkowski, Matthew A and Sengupta, Sohini and Li, Zhi and Li, Wei and Li, Jun and Payne, Samuel H and Fenyö, David and Miner, Jeffrey H and Walter, Matthew J and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Yang, Liming and Yang, Ju Dong and Yang, Ian and Yang, Hannah and Zenklusen, Jean C and Zhang, Hailei and Zhang, Wei and Zhang, Jiashan (Julia) and Zhang, Lizhi and Zhang, Jiexin and Zhang, Hongxin and Zhang, Hongzheng and Chudamani, Sudha and Liu, Wenbin and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Michael and Miller, Judy and Miller, Christopher A and Shmulevich, Ilya and Thorsson, Vesteinn and Akbani, Rehan and Broom, Bradley M and Hegde, Apurva M and Ju, Zhenlin and Kanchi, Rupa S and Korkut, Anil and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Ng, Kwok-Shing and Rao, Arvind and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 1, pp. 270 - 281.e3
Journal Article