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PLoS Genetics, ISSN 1553-7390, 04/2019, Volume 15, Issue 4, pp. e1008079 - e1008079
Characterizing the fitness landscape, a representation of fitness for a large set of genotypes, is key to understanding how genetic information is interpreted... 
RECOMBINATION | IN-VITRO | EVOLUTION | PREDICTABILITY | EPISTATIC INTERACTIONS | PROTEIN-STRUCTURE | SIGN EPISTASIS | SPECIATION | GENETICS & HEREDITY | SELECTION | MUTATIONAL PATHWAYS | Fungal Proteins - chemistry | Saccharomyces cerevisiae - genetics | Phylogeny | Amino Acids - genetics | Saccharomyces cerevisiae - metabolism | Amino Acids - metabolism | Genes, Fungal | Hydro-Lyases - metabolism | Hydro-Lyases - genetics | Yeasts - metabolism | Amino Acid Sequence | Models, Molecular | Genotype | Fungal Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Yeasts - genetics | Genetic Fitness | Epistasis, Genetic | Saccharomyces cerevisiae Proteins - metabolism | Models, Genetic | Hydro-Lyases - chemistry | Amino Acid Substitution | Evolution, Molecular | Fungal Proteins - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Enzymes | Physiological aspects | Genetic research | Amino acids | Fitness (Genetics) | Genetic aspects | Research | Biological assay | Methods | Visualization | Laboratories | Funding | Genomics | Epistasis | Genomes | Biology | Proteins | Genotype & phenotype | Histidine | Evolution | Genetics | Software | Mutation | Bioinformatics | Supervision | Genotypes | Fitness | Index Medicus | Variant genotypes | Protein sequencing | Evolutionary genetics | Sign epistasis | Fitness epistasis | Saccharomyces cerevisiae | Amino acid substitution
Journal Article
Bioinformatics, ISSN 1367-4803, 11/2018, Volume 34, Issue 21, pp. 3653 - 3658
Abstract Motivation Computational prediction of the effect of mutations on protein stability is used by researchers in many fields. The utility of the... 
MODIFIED FOLDX PROTOCOL | PROTEIN STABILITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SERVER | SEQUENCE | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Original Papers
Journal Article
BBA - Biomembranes, ISSN 0005-2736, 01/2014, Volume 1838, Issue 1, pp. 164 - 172
Knowledge of the energetic parameters of transmembrane helix–helix interactions is necessary for the establishment of a structure–energy relationship for... 
Detergent micelle | NMR spectroscopy | Dimerization | Transmembrane helix | Free energy | PROTEIN | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENERGETICS | MIXED MICELLES | PHOSPHOLIPASE-A2 ACTIVITY | SPATIAL STRUCTURE | BIOPHYSICS | DETERGENTS | DIMER | DOMAIN DIMERIZATION | ASSOCIATION | Receptor, Fibroblast Growth Factor, Type 3 - chemistry | Models, Chemical | Detergents - chemistry | Humans | Protein Multimerization | Molecular Sequence Data | Receptor, Fibroblast Growth Factor, Type 3 - metabolism | Vascular Endothelial Growth Factor Receptor-2 - genetics | Thermodynamics | Solutions | Micelles | Escherichia coli - metabolism | Binding Sites | Oligopeptides - chemistry | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amino Acid Sequence | Receptor, Fibroblast Growth Factor, Type 3 - genetics | Protein Structure, Secondary | Oligopeptides - genetics | Recombinant Proteins - chemistry | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Recombinant Proteins - genetics | Oligopeptides - metabolism | Vascular Endothelial Growth Factor Receptor-2 - chemistry | Escherichia coli - genetics | Nuclear Magnetic Resonance, Biomolecular - methods | Protein Binding | Kinetics | Measurement | Oligomers | Nuclear magnetic resonance spectroscopy | Detergents, Synthetic | Nuclear magnetic resonance | Analysis
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2014, Volume 289, Issue 20, pp. 14331 - 14340
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e93011 - e93011
Aims: Genome-wide association studies highlighted single nucleotide polymorphisms (SNPs) within the IFNL3/IL28B locus predict the treatment outcome for... 
CLEARANCE | THERAPY | MULTIDISCIPLINARY SCIENCES | TREATMENT RESPONSE | RIBAVIRIN | IFNL4 | PEGYLATED INTERFERON-ALPHA | Uzbekistan - epidemiology | Hepatitis C - drug therapy | Humans | Middle Aged | European Continental Ancestry Group | Hepatitis C - genetics | Male | Antiviral Agents - administration & dosage | Interferon-alpha - administration & dosage | Interleukins - genetics | Asian Continental Ancestry Group | Hepatitis C - epidemiology | Adult | Female | Polymorphism, Single Nucleotide | Hepacivirus | Virus diseases | Medical research | Care and treatment | Prognosis | Medicine, Experimental | Genetic aspects | Single nucleotide polymorphisms | Hepatitis C virus | Health aspects | Chromosomes | Prevalence studies (Epidemiology) | Haplotypes | Liver | Chronic infection | African Americans | Viruses | Leukocytes (mononuclear) | Infections | Genomes | Single-nucleotide polymorphism | Clinical outcomes | Hepatitis | Genotype & phenotype | Immunology | Acquired immune deficiency syndrome--AIDS | Polyethylene glycol | Human immunodeficiency virus--HIV | Peripheral blood mononuclear cells | Drug dosages | Public health | Deoxyribonucleic acid--DNA | Global health | Immunoglobulins | Cytokines | Patients | Ethnic factors | Virology | Medicine | Ethnicity | Gene frequency | Interferon | Hepatitis C | Index Medicus | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS | HIV | DNA | Human immunodeficiency virus
Journal Article
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