Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (66) 66
humans (63) 63
male (44) 44
myasthenia gravis (44) 44
female (43) 43
adult (39) 39
neurosciences (39) 39
middle aged (38) 38
aged (35) 35
clinical neurology (30) 30
myasthenia gravis - immunology (16) 16
quality of life (16) 16
myasthenia gravis - drug therapy (15) 15
myasthenia (14) 14
neurology (13) 13
severity of illness index (12) 12
aged, 80 and over (11) 11
aging (10) 10
japan (10) 10
myasthenia gravis - complications (10) 10
myasthenia gravis - pathology (10) 10
corticosteroids (9) 9
neuromuscular junctions (9) 9
patients (9) 9
research (9) 9
autoantibodies (8) 8
autoantibodies - blood (8) 8
hypoxia (8) 8
prednisolone (8) 8
thymoma (8) 8
treatment outcome (8) 8
adolescent (7) 7
animals (7) 7
antibodies (7) 7
brain (7) 7
pc12 cells (7) 7
quality-of-life (7) 7
rats (7) 7
retrospective studies (7) 7
thymoma - complications (7) 7
thymus (7) 7
young adult (7) 7
analysis (6) 6
calcineurin inhibitors (6) 6
care and treatment (6) 6
immunology (6) 6
ischemia (6) 6
myasthenia gravis - diagnosis (6) 6
myasthenia gravis - psychology (6) 6
phosphorylation (6) 6
thymectomy (6) 6
thymus neoplasms - complications (6) 6
age (5) 5
autoimmune diseases (5) 5
dose-response relationship, drug (5) 5
immunoglobulins (5) 5
medical research (5) 5
myasthenia gravis - blood (5) 5
myasthenia gravis - physiopathology (5) 5
original paper (5) 5
prednisolone - administration & dosage (5) 5
promoter (5) 5
protein (5) 5
research article (5) 5
therapy (5) 5
acetylcholine (4) 4
acetylcholine-receptor (4) 4
activation (4) 4
activities of daily living (4) 4
akt (4) 4
autoantibodies - immunology (4) 4
binding (4) 4
cd44 (4) 4
cell cycle (4) 4
cross-sectional studies (4) 4
diagnosis (4) 4
disease (4) 4
dna methylation (4) 4
double-blind (4) 4
fk506 (4) 4
further section (4) 4
g1-arrest (4) 4
hospitals (4) 4
immunotherapy (4) 4
interleukin-2 (4) 4
lymphocytes (4) 4
magnetic resonance imaging (4) 4
medicine, experimental (4) 4
mg-qol15 (4) 4
multidisciplinary sciences (4) 4
myasthenia gravis - surgery (4) 4
myasthenia gravis - therapy (4) 4
ocular myasthenia (4) 4
polymerase chain reaction (4) 4
prednisolone - therapeutic use (4) 4
rna, messenger - biosynthesis (4) 4
striatum (4) 4
surgery (4) 4
surveys and questionnaires (4) 4
thymus gland - pathology (4) 4
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. The new clinical guidelines: basic policy against generalized MG
by Utsugisawa, Kimiaki
Nihon rinsho. Japanese journal of clinical medicine, ISSN 0047-1852, 09/2015, Volume 73, pp. 488 - 494
Journal Article
Details down arrow
2. The new clinical guidelines: basic policy against generalized MG
by Utsugisawa, Kimiaki
Nihon rinsho. Japanese journal of clinical medicine, ISSN 0047-1852, 09/2015, Volume 73 Suppl 7, p. 488
Public Policy | Humans | Age of Onset | Quality of Life | Myasthenia Gravis - drug therapy | Thymus Gland - surgery | Myasthenia Gravis - surgery | Practice Guidelines as Topic
Journal Article
Details down arrow
3. Quality of life and advice for lifestyle in myasthenia gravis
by Nagane, Yuriko and Utsugisawa, Kimiaki
Nihon rinsho. Japanese journal of clinical medicine, ISSN 0047-1852, 09/2015, Volume 73, pp. 539 - 545
Journal Article
Details down arrow
4. Quality of life and advice for lifestyle in myasthenia gravis
by Nagane, Yuriko and Utsugisawa, Kimiaki
Nihon rinsho. Japanese journal of clinical medicine, ISSN 0047-1852, 09/2015, Volume 73 Suppl 7, p. 539
Life Style | Myasthenia Gravis - psychology | Humans | Quality of Life | Depression | Sleep Wake Disorders | Disease Progression
Journal Article
Details down arrow
5. Full Text Clinical burden and healthcare resource utilization associated with myasthenia gravis: Assessments from a Japanese claims database
by Murai, Hiroyuki and Hasebe, Miki and Murata, Tatsunori and Utsugisawa, Kimiaki
Clinical and Experimental Neuroimmunology, ISSN 1759-1961, 02/2019, Volume 10, Issue 1, pp. 61 - 68
An analysis of data from a Japanese health insurance claims database showed that a greater proportion of patients with refractory myasthenia gravis than... 
myasthenia gravis | respiratory failure | complications | claims analysis | health resources utilization | Medical research | Utilization | Myasthenia gravis | Databases | Medical care | Medicine, Experimental | Emergency medical services | Resource utilization | Parkinson's disease | Medicare | Neurodegenerative diseases | Parkinsons disease | Neuromuscular junctions | Emergency medical care | Myasthenia | Movement disorders
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Development of a novel immunoassay to select antibodies against intact membrane antigens by using the homogeneous AlphaLISA system
by Muneoka, Satoshi and Nakamura, Ryuichi and Hoshino, Masato and Utsugisawa, Kimiaki and Makino, Tomohiro
Journal of Bioscience and Bioengineering, ISSN 1389-1723, 10/2018, Volume 126, Issue 4, pp. 522 - 526
Membrane proteins, such as G-protein-coupled receptors and ion channels are attractive targets for antibody-based therapeutics as pharmaceutical and biotech... 
AlphaLISA | Myasthenia gravis | Antibody screening | Nicotinic acetylcholine receptor | Membrane proteins | TE671 | FOOD SCIENCE & TECHNOLOGY | EXTRACELLULAR DOMAIN | MUSCLE ACETYLCHOLINE-RECEPTOR | THERAPY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MAIN IMMUNOGENIC REGION | MYASTHENIA-GRAVIS | MONOCLONAL-ANTIBODIES | EXPRESSION | BINDING | Bungarotoxins - immunology | Receptors, Nicotinic - immunology | Immunoassay - instrumentation | Humans | Receptors, Nicotinic - analysis | Antibodies - analysis | Antibodies - immunology | Immunoassay - methods | Bungarotoxins - analysis | Antigens | Immunoglobulin G | Therapeutics | Homeopathy | Materia medica and therapeutics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Analysis of peripheral B cells and autoantibodies against the anti-nicotinic acetylcholine receptor derived from patients with myasthenia gravis using single-cell manipulation tools
by Makino, Tomohiro and Nakamura, Ryuichi and Terakawa, Maki and Muneoka, Satoshi and Nagahira, Kazuhiro and Nagane, Yuriko and Yamate, Jyoji and Motomura, Masakatsu and Utsugisawa, Kimiaki
PLoS ONE, ISSN 1932-6203, 10/2017, Volume 12, Issue 10, pp. e0185976 - e0185976
The majority of patients with myasthenia gravis (MG), an organ-specific autoimmune disease, harbor autoantibodies that attack the nicotinic acetylcholine... 
EXPERIMENTAL AUTOIMMUNE MYASTHENIA | SPECIFICITIES | ALPHA-SUBUNIT | LINE TE671 | MULTIDISCIPLINARY SCIENCES | EXTRACELLULAR DOMAIN | MAIN IMMUNOGENIC REGION | SERUM ANTIBODIES | MONOCLONAL-ANTIBODIES | BLOCKER THERAPY | FAB FRAGMENTS | Protein Subunits - immunology | Hybridomas - chemistry | Antibodies, Monoclonal - biosynthesis | Humans | Rats | Adoptive Transfer | Antibodies, Monoclonal - isolation & purification | Autoantibodies - biosynthesis | Receptors, Nicotinic - immunology | Animals | B-Lymphocytes - immunology | Flow Cytometry | Single-Cell Analysis - methods | Hybridomas - immunology | Autoantibodies - analysis | Myasthenia Gravis - genetics | Protein Subunits - antagonists & inhibitors | B-Lymphocytes - pathology | Primary Cell Culture | Myasthenia Gravis - immunology | Receptors, Nicotinic - genetics | Antibodies, Monoclonal - chemistry | Myasthenia Gravis - pathology | Protein Subunits - genetics | Myasthenia gravis | Research | B cells | Nicotinic receptors | Protein binding | Disease | Laboratories | Phages | Antibodies | Lymphocytes T | Cell immortalization | Immunity | Inflammatory diseases | Engineering | Phage display | Immunology | Rodents | Peripheral blood | Binding | Pathogens | Antigens | Immunoglobulins | Autoantibodies | Muscles | Adaptive immunity | Patients | Skeletal muscle | Pathogenicity | Neurology | Immunogenicity | Lymphocytes B | Immortalization | Affinity | Neuromuscular junctions | Acetylcholine receptors (nicotinic) | Genetic engineering | Myasthenia | Acetylcholine | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Health‐related quality‐of‐life and treatment targets in myasthenia gravis
by Utsugisawa, Kimiaki and Suzuki, Shigeaki and Nagane, Yuriko and Masuda, Masayuki and Murai, Hiroyuki and Imai, Tomihiro and Tsuda, Emiko and Konno, Shingo and Nakane, Shunya and Suzuki, Yasushi and Fujihara, Kazuo and Suzuki, Norihiro
Muscle & Nerve, ISSN 0148-639X, 10/2014, Volume 50, Issue 4, pp. 493 - 500
Introduction : The aim of this study was to determine factors affecting health‐related quality of life (HRQOL) and to propose appropriate treatment targets for... 
autoimmune diseases | cohort studies | treatment | myasthenia | quality of life | Myasthenia | Treatment | Autoimmune diseases | Cohort studies | Quality of life | CYTOSOLIC 5'-NUCLEOTIDASE 1A | INFLAMMATORY MYOPATHIES | MUSCLE | INCLUSION-BODY MYOSITIS | NEUROSCIENCES | CLINICAL NEUROLOGY | Severity of Illness Index | Cross-Sectional Studies | Myasthenia Gravis - psychology | Humans | Japan | Middle Aged | Myasthenia Gravis - therapy | Male | Statistics as Topic | Myasthenia Gravis - physiopathology | Self Concept | Adult | Female | Aged | Quality of Life - psychology | Health Status | Longitudinal Studies | Corticosteroids | Myasthenia gravis | Analysis | Prednisolone | Medical treatment | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study
by Howard, James F and Utsugisawa, Kimiaki and Benatar, Michael and Murai, Hiroyuki and Barohn, Richard J and Illa, Isabel and Jacob, Saiju and Vissing, John and Burns, Ted M and Kissel, John T and Muppidi, Srikanth and Nowak, Richard J and O'Brien, Fanny and Wang, Jing-Jing and Mantegazza, Renato and Mazia, Claudio Gabriel and Wilken, Miguel and Ortea, Carolina and Saba, Juliet and Rugiero, Marcelo and Bettini, Mariela and Vidal, Gonzalo and Vidal, Nuria and Garcia, Rebekah and Garcia, Sonia and Garcia, Alejandra Dalila and Lamont, Phillipa and Leong, Wai-Kuen and Boterhoven, Heidi and Fyfe, Beverly and Roberts, Leslie and Jasinarachchi, Mahi and Willlems, Natasha and Wanschitz, Julia and Löscher, Wolfgang and De Bleecker, Jan and Van den Abeele, Guy and de Koning, Kathy and De Mey, Katrien and Mercelis, Rudy and Wagemaekers, Linda and Mahieu, Delphine and Van Damme, Philip and Smetcoren, Charlotte and Stevens, Olivier and Verjans, Sarah and D'Hondt, Ann and Tilkin, Petra and Alves de Siqueira Carvalho, Alzira and Hasan, Rosa and Dias Brockhausen, Igor and Feder, David and Ambrosio, Daniel and Melo, Ana Paula and Rocha, Rosana and Rosa, Bruno and Veiga, Thabata and Augusto da Silva, Luiz and Gonçalves Geraldo, Jordana and da Penha Morita Ananias, Maria and Nogueira Coelho, Erica and Paiva, Gabriel and Pozo, Marina and Prando, Natalia and Dada Martineli Torres, Debora and Fernanda Butinhao, Cristiani and Coelho, Erica and Renata Cubas Volpe, Luciana and Duran, Gustavo and Gomes da Silva, Tamires Cristina and Otavio Maia Gonçalves, Luiz and Pazetto, Lucas Eduardo and Souza Duca, Luciana and Suriane Fialho, Tomás Augusto and Gheller Friedrich, Maurício André and Guerreiro, Alexandre and Mohr, Henrique and Pereira Martins, Maurer and da Cruz Pacheco, Daiane and Macagnan, Ana Paula and de Cassia Santos, Aline and Bulle Oliveira, Acary Souza and Amaral de Andrade, Ana Carolina and Annes, Marcelo and Cavalcante Lino, Valeria and Pinto, Wladimir and Miranda, Carolina and Carrara, Fernanda and Souza, Iandra and Genge, Angela and Massie, Rami and Campbell, Natasha and Bril, Vera and Katzberg, Hans and Soltani, Mehran and Ng, Eduardo and Siddiqi, Zaeem and Phan, Celile and Blackmore, Derrick and Vohanka, Stanislav and ... and REGAIN Study Grp and REGAIN Study Group
The Lancet Neurology, ISSN 1474-4422, 12/2017, Volume 16, Issue 12, pp. 976 - 986
Complement is likely to have a role in refractory generalised myasthenia gravis, but no approved therapies specifically target this system. Results from a... 
TRIAL | ENDPLATE | LOCALIZATION | COMPLEMENT INHIBITOR ECULIZUMAB | DAILY LIVING PROFILE | PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA | ACETYLCHOLINE-RECEPTOR | END-PLATE | CLINICAL NEUROLOGY | Severity of Illness Index | Antibodies, Monoclonal, Humanized - adverse effects | Double-Blind Method | Myasthenia Gravis - blood | Outcome Assessment (Health Care) | Autoantibodies - blood | Humans | Middle Aged | Male | Antibodies, Monoclonal, Humanized - administration & dosage | Myasthenia Gravis - physiopathology | Antibodies, Monoclonal, Humanized - pharmacology | Adult | Female | Receptors, Cholinergic - immunology | Aged | Myasthenia Gravis - drug therapy | Drug Resistance | Studies | Neurology | Immunoglobulins | Activities of daily living | Myasthenia gravis | Transplants & implants | Neuromuscular junctions | Acetylcholine | Myasthenia | Patients | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Three types of striational antibodies in myasthenia gravis
by Suzuki, Shigeaki and Utsugisawa, Kimiaki and Nagane, Yuriko and Suzuki, Norihiro
Autoimmune Diseases, ISSN 2090-0430, 2011, Volume 1, Issue 1, pp. 740583 - 7
Myasthenia gravis (MG) is caused by antibodies that react mainly with the acetylcholine receptor on the postsynaptic site of the neuromuscular junction. A wide... 
Viral antibodies | Care and treatment | Myasthenia gravis | Antibodies | Diagnosis | Research | Health aspects
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Rationale for the clinical guidelines for myasthenia gravis in Japan
: Rationale for Japanese MG guidelines
by Murai, Hiroyuki and Utsugisawa, Kimiaki and Nagane, Yuriko and Suzuki, Shigeaki and Imai, Tomihiro and Motomura, Masakatsu
Annals of the New York Academy of Sciences, ISSN 0077-8923, 02/2018, Volume 1413, Issue 1, pp. 35 - 40
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Antibodies against the main immunogenic region of the acetylcholine receptor correlate with disease severity in myasthenia gravis
by Masuda, Tomoko and Motomura, Masakatsu and Utsugisawa, Kimiaki and Nagane, Yuriko and Nakata, Ruka and Tokuda, Masahiro and Fukuda, Taku and Yoshimura, Toshiro and Tsujihata, Mitsuhiro and Kawakami, Atsushi
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 09/2012, Volume 83, Issue 9, pp. 935 - 940
ObjectiveWe developed an assay that detects autoantibodies against the main immunogenic region (MIR) located at the extracellular end of the nicotinic... 
AUTOANTIBODIES | SURGERY | PROTEIN 4 | MUSK | ANTIGENIC STRUCTURE | PSYCHIATRY | CLINICAL NEUROLOGY | OCULAR MYASTHENIA | EXTRAOCULAR-MUSCLE | MONOCLONAL-ANTIBODIES | NEUROMUSCULAR-JUNCTION | CLINICAL CORRELATIONS | BINDING | Severity of Illness Index | Receptors, Nicotinic - drug effects | Myasthenia Gravis - blood | Antibodies, Monoclonal - pharmacology | Autoantibodies - blood | Humans | Middle Aged | Rats, Inbred Lew | Rats | Male | Biomarkers - blood | Myasthenia Gravis - diagnosis | Receptors, Nicotinic - immunology | Animals | Antibodies, Monoclonal - administration & dosage | Female | Retrospective Studies | Myasthenia Gravis - immunology | Viral antibodies | Receptors | Myasthenia gravis | Physiological aspects | Antibodies | Development and progression | Acetylcholine | Research | Health aspects | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Oral corticosteroid dosing regimen and long-term prognosis in generalised myasthenia gravis: a multicentre cross-sectional study in Japan
by Imai, Tomihiro and Utsugisawa, Kimiaki and Murai, Hiroyuki and Tsuda, Emiko and Nagane, Yuriko and Suzuki, Yasushi and Minami, Naoya and Uzawa, Akiyuki and Kawaguchi, Naoki and Masuda, Masayuki and Konno, Shingo and Suzuki, Hidekazu and Akaishi, Tetsuya and Aoki, Masashi
Journal of Neurology, Neurosurgery & Psychiatry, ISSN 0022-3050, 05/2018, Volume 89, Issue 5, pp. 513 - 517
ObjectiveWe examined the correlation between the dosing regimen of oral prednisolone (PSL) and the achievement of minimal manifestation status or better on PSL... 
TRIAL | SURGERY | TREATMENT STRATEGY | PSYCHIATRY | DOUBLE-BLIND | IMMUNOGLOBULIN | CLINICAL NEUROLOGY | Neurology | Immunoglobulins | Patient satisfaction | Variance analysis | postintervention status | prednisolone | logistic regression analysis | Neuromuscular | calcineurin inhibitor | myasthenia gravis | 1506
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Oral corticosteroid therapy and present disease status in myasthenia gravis
by Imai, Tomihiro and Suzuki, Shigeaki and Tsuda, Emiko and Nagane, Yuriko and Murai, Hiroyuki and Masuda, Masayuki and Konno, Shingo and Suzuki, Yasushi and Nakane, Shunya and Fujihara, Kazuo and Suzuki, Norihiro and Utsugisawa, Kimiaki
Muscle & Nerve, ISSN 0148-639X, 05/2015, Volume 51, Issue 5, pp. 692 - 696
Introduction : The aim of this study was to elucidate the effectiveness of oral prednisolone (PSL) according to dosing regimen in 472 patients with myasthenia... 
myasthenia gravis | immunomodulation therapy | postintervention status | cross‐sectional study | prednisolone | Immunomodulation therapy | Myasthenia gravis | Cross-sectional study | Postintervention status | Prednisolone | CONTROLLED-TRIAL | CLINICAL-TRIAL | IMMUNOGLOBULIN | AZATHIOPRINE | FK506 | NEUROSCIENCES | CLINICAL NEUROLOGY | PLASMA-EXCHANGE | PREDNISONE | DOUBLE-BLIND | cross-sectional study | MICROEMULSION | CYCLOSPORINE | Prednisolone - administration & dosage | Humans | Middle Aged | Male | Plasma Exchange | Adrenal Cortex Hormones - therapeutic use | Myasthenia Gravis - diagnosis | Dose-Response Relationship, Drug | Young Adult | Aged, 80 and over | Adult | Female | Prednisolone - therapeutic use | Severity of Illness Index | Cross-Sectional Studies | Administration, Oral | Japan | Treatment Outcome | Combined Modality Therapy | Regression Analysis | Immunoglobulins, Intravenous - therapeutic use | Adolescent | Aged | Longitudinal Studies | Myasthenia Gravis - drug therapy | Adrenal Cortex Hormones - administration & dosage | Corticosteroids | Autoimmune diseases | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text Association between glucocorticoid-induced osteoporosis and myasthenia gravis: A cross-sectional study
by Konno, Shingo and Suzuki, Shigeaki and Masuda, Masayuki and Nagane, Yuriko and Tsuda, Emiko and Murai, Hiroyuki and Imai, Tomihiro and Fujioka, Toshiki and Suzuki, Norihiro and Utsugisawa, Kimiaki
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, pp. e0126579 - e0126579
Purpose To investigate the association between glucocorticoid-induced osteoporosis and myasthenia gravis (MG) using a cross-sectional survey in Japan. Methods... 
DENSITY | MULTIDISCIPLINARY SCIENCES | Bone Density | Myasthenia Gravis - epidemiology | Osteoporosis - chemically induced | Humans | Middle Aged | Fractures, Bone - epidemiology | Male | Myasthenia Gravis - chemically induced | Myasthenia Gravis - physiopathology | Fractures, Bone - physiopathology | Quality of Life | Adult | Female | Aged | Fractures, Bone - chemically induced | Osteoporosis - physiopathology | Glucocorticoids - adverse effects | Osteoporosis - epidemiology | Complications and side effects | Osteoporosis | Myasthenia gravis | Corticosteroids | Dosage and administration | Research | Risk factors | Lupus | Activities of daily living | Glucocorticoids | Laboratories | Patients | Quality of life | Studies | Ethics | Neurology | Hospitals | Fractures | Rheumatoid arthritis | Neuromuscular junctions | Biocompatibility | Bone mineral density | Bone density | Myasthenia | Bone | Quality assessment | Drug dosages | Cross sections | Prednisolone | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Full Text Insights into the classification of myasthenia gravis
by Akaishi, Tetsuya and Yamaguchi, Takuhiro and Suzuki, Yasushi and