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PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, p. e115778
Aims: Despite the wide use of metformin in metabolically challenged pregnancies, the long-term effects on the metabolism of the offspring are not known. We... 
OBESE MICE | INSULIN | WHITE ADIPOSE-TISSUE | RESPIRATORY-CHAIN | ACTIVATED PROTEIN-KINASE | MECHANISM | MULTIDISCIPLINARY SCIENCES | BROWN ADIPOCYTES | GESTATIONAL DIABETES-MELLITUS | EXPRESSION | GLUCOSE-TOLERANCE | Fetus - metabolism | Body Weight - drug effects | Diet, High-Fat - adverse effects | Adipocytes - cytology | Male | Adipocytes - drug effects | Adipokines - blood | Adipose Tissue, White - cytology | Liver - drug effects | Lipids - blood | Female | Glucose Tolerance Test | Cell Size - drug effects | Liver - metabolism | Metformin - pharmacology | Mice, Inbred C57BL | Transcriptome - drug effects | Prenatal Exposure Delayed Effects - metabolism | Fetus - cytology | Fetus - drug effects | Pregnancy | Prenatal Exposure Delayed Effects - genetics | Animals | Mice | Blood Glucose - metabolism | Diet | Pregnant women | Analysis | Liver | Body weight | Physiological aspects | Metformin | Glucose | Dextrose | Neonates | Adipose tissue | Disease | Body fat | Weaning | Adipocytes | Gestation | Kinases | Body composition | High fat diet | Proteins | Electron transport chain | Mitochondria | Annotations | Body composition (biology) | Rodents | Prenatal experience | Age | Carbohydrates | Obesity | Exposure | Pharmacology | Metabolism | Gene expression | Insulin | Glucose tolerance | Progeny | Offspring | Weight control | DNA microarrays | Metabolic pathways | Diabetes | Electron transport | Long-term effects
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e56594
Aims: The antidiabetic drug metformin is currently used prior and during pregnancy for polycystic ovary syndrome, as well as during gestational diabetes... 
POLYCYSTIC-OVARY-SYNDROME | EPIGENETIC MECHANISMS | WOMEN | ACTIVATED PROTEIN-KINASE | NEONATAL LEPTIN TREATMENT | MULTIDISCIPLINARY SCIENCES | INSULIN-SENSITIZING DRUGS | GENE-EXPRESSION | AMPK | INDUCED OBESITY | PREGNANCY | Prenatal Exposure Delayed Effects | Fetus - metabolism | Body Weight - drug effects | Diet, High-Fat - adverse effects | Male | Liver - growth & development | Maternal Exposure | Hypoglycemic Agents - blood | Liver - drug effects | Female | Metformin - blood | Glucose Tolerance Test | Glucose Transporter Type 4 - genetics | Membrane Proteins - genetics | Metformin - pharmacology | Mice, Inbred C57BL | Hypoglycemic Agents - pharmacology | Fetus - drug effects | Gene Expression Regulation - drug effects | Pregnancy | Eating - drug effects | Organ Size - drug effects | Phenotype | Animals | Fetus - embryology | Mice | Type 2 diabetes | Medical research | Dams | RNA | Liver | Body weight | Gene expression | Diet | Stein-Leventhal syndrome | Pregnant women | Medicine, Experimental | Genetic aspects | Metformin | Diabetes therapy | Neonates | Brain | Fuel consumption | Tissue analysis | Glucose | Kinases | High fat diet | Rodents | Prenatal experience | Polycystic ovary syndrome | Fetuses | Diabetes mellitus | Pharmacology | Exposure | Chemical compounds | Embryos | Studies | Glucose tolerance | Progeny | Offspring | DNA microarrays | Food intake
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 04/2018, Volume 9
Neuropeptide Y (NPY) plays an important role in the regulation of energy homeostasis in the level of central and sympathetic nervous systems (SNSs). Genetic... 
Neuropeptide Y | Obesity | receptor | The metabolic syndrome | BIIE0246 | Energy metabolism | Care and treatment | Bioenergetics | Development and progression | Genetic aspects | Health aspects | Y2-receptor | the metabolic syndrome | obesity | neuropeptide Y
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 10/2011, Volume 7, Issue 10, p. e1002257
Journal Article
International Journal of Peptides, ISSN 1687-9767, 2012, Volume 2012, pp. 452524 - 10
Neuropeptide Y (NPY) is a neurotransmitter associated with feeding and obesity. We have constructed an NPY transgenic mouse model (OE-NPY(DBH) mouse), where... 
Obesity | Metabolic diseases | Genetic aspects | Diet therapy | Observations | Health aspects
Journal Article
Neurochemical Research, ISSN 0364-3190, 07/2014, Volume 39, Issue 7, p. 1192
Journal Article
The Journal of endocrinology, ISSN 0022-0795, 07/2017, Volume 234, Issue 1, pp. 57 - 72
A gain-of-function polymorphism in human neuropeptide Y (NPY) gene (rs16139) associates with metabolic disorders and earlier onset of type 2 diabetes (T2D).... 
hepatic cholesterol synthesis oxidative stress | glucose metabolism | Y1-receptor | neuropeptide Y | type 2 diabetes NAFLD | NERVOUS-SYSTEM | PREPRONEUROPEPTIDE-Y | FATTY LIVER-DISEASE | IMPAIRED GLUCOSE-TOLERANCE | INSULIN SENSITIVITY | VLDL-TRIGLYCERIDE SECRETION | DIABETIC-PATIENTS | LEU7PRO POLYMORPHISM | ENDOCRINOLOGY & METABOLISM | CHOLESTEROL-SYNTHESIS | INDUCED OBESITY | Metabolic Syndrome - etiology | Gene Expression | Adrenergic Neurons - metabolism | Liver - metabolism | Mice, Inbred C57BL | Metabolic Syndrome - metabolism | Mice, Transgenic | Neuropeptide Y - genetics | Neuropeptide Y - adverse effects | Sympathetic Nervous System - physiopathology | Cholesterol - metabolism | Energy Intake | Obesity - metabolism | Animals | Energy Metabolism | Hypercholesterolemia - etiology | Glucose - metabolism | Diabetes Mellitus, Type 2 - etiology | Receptors, Neuropeptide Y - antagonists & inhibitors | Mice | Fatty Acids - metabolism | Receptors, Neuropeptide Y - physiology | Neuropeptide Y - physiology | Fatty Liver - etiology | Oxidative stress | Hyperinsulinemia | Energy metabolism | Streptozocin | Pyruvic acid | Nervous system | Neuropeptides | Glucose | Metabolic syndrome | Gene polymorphism | Glucose metabolism | Hyperglycemia | Fatty liver | Rodents | Aging | Lipid metabolism | Neuropeptide Y | Obesity | Diabetes mellitus | Inflammation | Sympathetic nervous system | Fatty acids | Insulin | Cholesterol | Hypercholesterolemia | Interleukin 10 | Norepinephrine | Metabolic disorders | Energy storage
Journal Article
Neurochemical Research, ISSN 0364-3190, 07/2014, Volume 39, Issue 7, pp. 1183 - 1191
  Gamma-aminobutyric acid type A receptors (GABA^sub A^R) are allosterically modulated by the nonsteroidal anti-inflammatory drugs diflunisal and fenamates.... 
Journal Article
Marine Ecology Progress Series, ISSN 0171-8630, 2011, Volume 423, pp. 1 - 14
We assessed the responses of a nitrogen (N)-limited < 10 mu m plankton community from the Baltic Sea to the 12 d photochemical transformation of dissolved... 
Phytoplankton | Bacterioplankton | Trophic transfer | Dissolved organic nitrogen | Apparent quantum yield | Photochemistry | CARBON | FOOD-WEB | SIZE | HUMIC LAKE | BACTERIAL-GROWTH | EUTROPHICATION | NORTHERN BALTIC SEA | PLANKTON COMMUNITIES | QUANTUM YIELD | MARINE & FRESHWATER BIOLOGY | OCEANOGRAPHY | NITROGEN | ECOLOGY
Journal Article
by Knip, Mikael and Åkerblom, Hans K and Altaji, Eva and Becker, Dorothy and Bruining, Jan and Castano, Luis and Danne, Thomas and De Beaufort, Carine and Dosch, Hans-Michael and Dupre, John and Fraser, William D and Howard, Neville and Ilonen, Jorma and Konrad, Daniel and Kordonouri, Olga and Krischer, Jeffrey P and Lawson, Margaret L and Ludvigsson, Johnny and Madacsy, Laszlo and Mahon, Jeffrey L and Ormisson, Anne and Palmer, Jerry P and Pozzilli, Paolo and Savilahti, Erkki and Serrano-Rios, Manuel and Songini, Marco and Taback, Shayne and Vaarala, Outi and White, Neil H and Virtanen, Suvi M and Wasikowa, Renata and Mandrup-Poulsen, Thomas and Arjas, Elja and Lernmark, Åke and Läärä, Esa and Schmidt, Barbara and Hyytinen, Mila and Koski, Katriina and Koski, Matti and Merentie, Kristiina and Pajakkala, Eeva and Reunanen, Antti and Salonen, Marja and Terhonen, Tuija and Virkkunen, Seija and Cuthbertson, David and Gainer, Bruce and Hadley, David and Malloy, Jamie and Nallamshetty, Lavanya and Shanker, Linda and Bradley, Brenda and Lough, Gigi and Fraser, William and Sermer, Mathew and Taback, Shayne and Franciscus, Margaret and Nucci, Anita and Palmer, Jerry and Alahuhta, Kirsi and Bärlund, Sonja and Korhonen, Tuuli and Kovanen, Lea and Lehtonen, Eveliina and Niinistö, Sari and Pekkala, Minna and Sorkio, Susa and Toivanen, Liisa and Vähätalo, Liisa and Uusitalo, Ulla and Öhman, Taina and Bongiorno, Ros and Catteau, Jacki and Fraser, Glenda and Lloyd, Margaret and Crock, Patricia and Giles, Michelle and Siech, Krystyna and See, Denise Wong and Brown, Christina and Craig, Maria and Johnston, Amanda and Bere, Lynda J and Clarson, Cheril L and Jenner, Morris and McManus, Ruth and Renato, Natale and Lovell, Marge and Higo, Debbie and Kent, Nancy and Kwan, Jennifer and Marshall, Colleen and Metzger, Daniel and Chanoine, Jean-Pierre and Stewart, Laura and Thompson, David and Edwards, Alun and Lange, Ian and Mercer, Julia and Pacaud, Daniele and ... and TRIGR Study Group and Writing Group for the TRIGR Study Group and Medicinska fakulteten and Region Östergötland and Linköpings universitet and Institutionen för klinisk och experimentell medicin and H.K.H. Kronprinsessan Victorias barn- och ungdomssjukhus and Barn- och kvinnocentrum and Avdelningen för barns och kvinnors hälsa
JAMA - Journal of the American Medical Association, ISSN 0098-7484, 01/2018, Volume 319, Issue 1, pp. 38 - 48
Journal Article