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aged, 80 and over (12) 12
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1. Full Text Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial
by Valgimigli, Marco, Dr and Gagnor, Andrea, MD and Calabró, Paolo, MD and Frigoli, Enrico, MD and Leonardi, Sergio, MD and Zaro, Tiziana, MD and Rubartelli, Paolo, MD and Briguori, Carlo, MD and Andò, Giuseppe, MD and Repetto, Alessandra, MD and Limbruno, Ugo, MD and Cortese, Bernardo, MD and Sganzerla, Paolo, MD and Lupi, Alessandro, MD and Galli, Mario, MD and Colangelo, Salvatore, MD and Ierna, Salvatore, MD and Ausiello, Arturo, MD and Presbitero, Patrizia, MD and Sardella, Gennaro, Prof and Varbella, Ferdinando, MD and Esposito, Giovanni, MD and Santarelli, Andrea, MD and Tresoldi, Simone, MD and Nazzaro, Marco, MD and Zingarelli, Antonio, MD and de Cesare, Nicoletta, MD and Rigattieri, Stefano, MD and Tosi, Paolo, MD and Palmieri, Cataldo, MD and Brugaletta, Salvatore, MD and Rao, Sunil V, MD and Heg, Dik, PhD and Rothenbühler, Martina, MSc and Vranckx, Pascal, MD and Jüni, Peter, Prof and MATRIX Investigators
Lancet, The, ISSN 0140-6736, 2015, Volume 385, Issue 9986, pp. 2465 - 2476
Summary Background It is unclear whether radial compared with femoral access improves outcomes in unselected patients with acute coronary syndromes undergoing... 
Internal Medicine | LEARNING-CURVE | SITE | MEDICINE, GENERAL & INTERNAL | ANGIOGRAPHY | METAANALYSIS | ACUTE MYOCARDIAL-INFARCTION | OUTCOMES | ST-SEGMENT ELEVATION | CARDIOVASCULAR DATA REGISTRY | INTERVENTION | ASSOCIATION | Catheterization, Peripheral - methods | Blood Loss, Surgical - prevention & control | Humans | Acute Coronary Syndrome - mortality | Male | Survival Rate | Treatment Outcome | Cause of Death | Coronary Angiography | Radial Artery | Percutaneous Coronary Intervention - methods | Acute Coronary Syndrome - surgery | Female | Femoral Artery | Aged | Blood Loss, Surgical - mortality | Catheterization, Peripheral - adverse effects | Clinical trials | Care and treatment | Coronary heart disease | Cardiac patients | Heart attacks | Acute coronary syndromes | Cardiology | Mortality | Veins & arteries | Index Medicus | Abridged Index Medicus
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2. Full Text Unrestricted randomised use of two new generation drug-eluting coronary stents: 2-year patient-related versus stent-related outcomes from the RESOLUTE All Comers trial
by Silber, Sigmund, Prof and Windecker, Stephan, Prof and Vranckx, Pascal, MD and Serruys, Patrick W, Prof and RESOLUTE All Corners Investigators and RESOLUTE All Comers investigators
Lancet, The, ISSN 0140-6736, 2011, Volume 377, Issue 9773, pp. 1241 - 1247
Summary Background In the RESOLUTE All Comers trial, the Resolute zotarolimus-eluting stent was non-inferior to the Xience V everolimus-eluting stent for the... 
Internal Medicine | SYSTEM | LEADERS | MEDICINE, GENERAL & INTERNAL | REVASCULARIZATION | MULTICENTER | EFFICACY | THROMBOSIS | IMPLANTATION | POLYMER | NATURAL-HISTORY | ARTERY-DISEASE | Prospective Studies | Follow-Up Studies | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Death, Sudden, Cardiac - prevention & control | Male | Secondary Prevention - methods | Adult | Female | Myocardial Revascularization - statistics & numerical data | Everolimus | Drug-Eluting Stents | Sirolimus - analogs & derivatives | Sirolimus - therapeutic use | Europe | Coronary Restenosis - prevention & control | Treatment Outcome | Coronary Restenosis - diagnostic imaging | Coronary Angiography | Confounding Factors (Epidemiology) | Coronary Artery Disease - therapy | Aged | Myocardial Infarction - prevention & control | Israel | Complications and side effects | Usage | Dosage and administration | Cardiovascular diseases | Drug therapy | Health aspects | Stent (Surgery) | Cardiovascular agents | Heart attacks | Cardiovascular disease | Circulatory system | Clinical medicine | Acute coronary syndromes | Stents | Blood clots | Index Medicus | Abridged Index Medicus
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3. Full Text Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial
by Anand, Sonia S and Bosch, Jackie and Eikelboom, John W and Connolly, Stuart J and Diaz, Rafael and Widimsky, Peter and Aboyans, Victor and Alings, Marco and Kakkar, Ajay K and Keltai, Katalin and Maggioni, Aldo P and Lewis, Basil S and Störk, Stefan and Zhu, Jun and Lopez-Jaramillo, Patricio and O'Donnell, Martin and Commerford, Patrick J and Vinereanu, Dragos and Pogosova, Nana and Ryden, Lars and Fox, Keith A A and Bhatt, Deepak L and Misselwitz, Frank and Varigos, John D and Vanassche, Thomas and Avezum, Alvaro A and Chen, Edmond and Branch, Kelley and Leong, Darryl P and Bangdiwala, Shrikant I and Hart, Robert G and Yusuf, Salim and SALA, JORGELINA and CARTASEGNA, LUIS and VICO, MARISA and HOMINAL, MIGUEL ANGEL and HASBANI, EDUARDO and CACCAVO, ALBERTO and ZAIDMAN, CESAR and VOGEL, DANIEL and HRABAR, ADRIAN and SCHYGIEL, PABLO OMAR and CUNEO, CARLOS and LUQUEZ, HUGO and MACKINNON, IGNACIO J and AHUAD GUERRERO, RODOLFO ANDRES and COSTABEL, JUAN PABLO and BARTOLACCI, INES PALMIRA and MONTANA, OSCAR and BARBIERI, MARIA and GOMEZ VILAMAJO, OSCAR and GARCIA DURAN, RUBEN OMAR and SCHIAVI, LILIA BEATRIZ and GARRIDO, MARCELO and INGARAMO, ADRIAN and BORDONAVA, ANSELMO PAULINO and PELAGAGGE, MARIA JOSE and NOVARETTO, LEONARDO and ALBISU DI GENNERO, JUAN PABLO and IBANEZ SAGGIA, LUZ MARIA and ALVAREZ, MOIRA and VITA, NESTOR ALEJANDRO and MACIN, STELLA MARIS and DRAN, RICARDO DARIO and CARDONA, MARCELO and GUZMAN, RANDOLPH and GUZMAN, LUIS and SARJANOVICH, RODOLFO JUAN and CUADRADO, JESUS and NANI, SEBASTIAN and LITVAK BRUNO, MARCOS RAUL and CHACON, CAROLINA and MAFFEI, LAURA ELENA and GRINFELD, DIEGO and VENSENTINI, NATALIA and MAJUL, CLAUDIO RODOLFO and LUCIARDI, HECTOR LUCAS and GONZALEZ COLASO, PATRICIA DEL CARMEN and FERRE PACORA, FREDY ANTONI and VAN DEN HEUVEL, PAUL and VERHAMME, PETER and ECTOR, BAVO and DEBONNAIRE, PHILIPPE and VAN DE BORNE, PHILIPPE and LEROY, JEAN and SCHROE, HERMAN and VRANCKX, PASCAL and ELEGEERT, IVAN and HOFFER, ETIENNE and DUJARDIN, KARL and INDIO DO BRASIL, CLARISSE and PRECOMA, DALTON and ABRANTES, JOSE ANTONIO and MANENTI, EULER and REIS, GILMAR and SARAIVA, JOSE and MAIA, LILIA and HERNANDES, MAURO and ROSSI, PAULO and ROSSI DOS SANTOS, FABIO and ... and COMPASS Investigators
The Lancet, ISSN 0140-6736, 01/2018, Volume 391, Issue 10117, pp. 219 - 229
Patients with peripheral artery disease have an increased risk of cardiovascular morbidity and mortality. Antiplatelet agents are widely used to reduce these... 
MORTALITY | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | MANAGEMENT | THERAPY | OUTPATIENTS | CARDIOVASCULAR EVENT RATES | PREVENTION | RISK | Myocardial Infarction - epidemiology | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Carotid Artery Diseases - complications | Male | Peripheral Arterial Disease - complications | Rivaroxaban - administration & dosage | Aspirin - administration & dosage | Factor Xa Inhibitors - administration & dosage | Incidence | Dose-Response Relationship, Drug | Rivaroxaban - adverse effects | Aspirin - adverse effects | Platelet Aggregation Inhibitors - administration & dosage | Cardiovascular Diseases - mortality | Female | Stroke - epidemiology | Aspirin - therapeutic use | Lower Extremity - surgery | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Myocardial Infarction - etiology | Rivaroxaban - therapeutic use | Carotid Artery Diseases - drug therapy | Platelet Aggregation Inhibitors - adverse effects | Stroke - prevention & control | Double-Blind Method | Drug Administration Schedule | Peripheral Arterial Disease - drug therapy | Carotid Artery Diseases - epidemiology | Morbidity | Factor Xa Inhibitors - therapeutic use | Stroke - etiology | Peripheral Arterial Disease - epidemiology | Factor Xa Inhibitors - adverse effects | Aged | Myocardial Infarction - prevention & control | Amputation - statistics & numerical data | Hemorrhage - chemically induced | Lower Extremity - blood supply | Cardiac arrhythmia | Anticoagulants | Aspirin | Stroke | Heart attacks | Medical imaging | Mortality | Clinical trials | Cardiovascular disease | Patients | Disease control | Carotid arteries | Disease prevention | Coronary vessels | Blood pressure | Carotid artery | Acute coronary syndromes | Thromboembolism | Health risk assessment | Index Medicus | Abridged Index Medicus
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4. Full Text Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial
by Vranckx, Pascal and Valgimigli, Marco and Jüni, Peter and Hamm, Christian and Steg, Philippe Gabriel and Steg, Gabriel and Heg, Dik and van Es, Gerrit Anne and McFadden, Eugene P and McFadden, Eugene and Onuma, Yoshinobu and van Meijeren, Cokky and Chichareon, Ply and Benit, Edouard and Möllmann, Helge and Janssens, Luc and Ferrario, Maurizio and Moschovitis, Aris and Zurakowski, Aleksander and Dominici, Marcello and Van Geuns, Robert Jan and Huber, Kurt and Slagboom, Ton and Serruys, Patrick and Serruys, Patrick W and Windecker, Stephan and Abdellaoui, Mohamed and Adlam, David and Akin, Ibrahim and Albarran Gonzalez-Trevilla, Agustin and Almeida, Manuel and Alves Lemos Neto, Pedro and Aminian, Adel and Anderson, Richard and Andreae, Rick and Angioi, Michael and Asano, Taku and Barbato, Emanuele and Barlis, Peter and Barraud, Pascal and Bertrand, Olivier and Beygui, Farzin and Bolognese, Leonardo and Botelho, Roberto and Bouwman, Coby and Bressers, Marco and Brunel, Philippe and Buszman, Pawel and Buysschaert, Ian and Canas da Silva, Pedro and Carrie, Didier and Cequier, Angel and Chin Chang, Chun and Chowdhary, Saqib and Collet, Carlos and Colombo, Antonio and Cotton, James and Cruz Ferreira, Rui and Curello, Salvatore and Curzen, Nick and de Bot, Judith and de Vreede, Tone and Delle Karth, Georg and Dijksma, Lynn and Édes, István and Eeckhout, Eric and Eitel, Ingo and Faluközy, József and Fath-Ordoubadi, Farzin and Fontos, Geza and Francisco Diaz, Jose and Freitas Quintella, Edgard and Frey, Bernhard and Friedrich, Guy and Galasko, Gavin and Galuszka, Grzegorz and Gama Ribeiro, Vasco and Garg, Scot and Gargiulo, Giuseppe and Geisler, Tobias and Gelev, Valeri and Ghandilyan, Art and Goicolea, Javier and Gori, Tommaso and Gragnano, Felice and Guimarães, Ana and Haude, Michael and Heijke, Pieter and Hernández Antolin, Rosa Ana and Hildick-Smith, David and Hillen, Dorien and Hoekman, Ina and Hofma, Sjoerd and Holmvang, Lene and Hoole, Stephen and Horváth, Iván and Hugense, Annemarie and Ibrahim, Karim and Iñiguez, Andres and Isaaz, Karl and ... and GLOBAL LEADERS Investigators
The Lancet, ISSN 0140-6736, 09/2018, Volume 392, Issue 10151, pp. 940 - 949
We hypothesised that ticagrelor, in combination with aspirin for 1 month, followed by ticagrelor alone, improves outcomes after percutaneous coronary... 
DEFINITIONS | MEDICINE, GENERAL & INTERNAL | BIODEGRADABLE POLYMER | METAANALYSIS | DUAL-ANTIPLATELET THERAPY | MYOCARDIAL-INFARCTION | ACADEMIC RESEARCH CONSORTIUM | CLINICAL-TRIALS | ACUTE CORONARY SYNDROMES | DURABLE POLYMER | INTERVENTION | Myocardial Infarction - mortality | Purinergic P2Y Receptor Antagonists - administration & dosage | Humans | Middle Aged | Male | Coronary Artery Disease - drug therapy | Coronary Artery Disease - mortality | Adenosine - administration & dosage | Ticlopidine - analogs & derivatives | Aspirin - administration & dosage | Drug-Eluting Stents - adverse effects | Coronary Angiography | Adenosine - analogs & derivatives | Platelet Aggregation Inhibitors - administration & dosage | Intention to Treat Analysis | Ticlopidine - administration & dosage | Clopidogrel | Female | Aged | Myocardial Infarction - prevention & control | Drug Therapy, Combination | Ticagrelor | Percutaneous Coronary Intervention | Aggregation | Blood platelets | Analysis | Myocardial infarction | Intervention | Therapy | Surgical implants | Heart attacks | Disorders | Cardiovascular disease | Drug delivery | Bleeding | Subgroups | Consortia | Randomization | Motivation | Implants | Heart diseases | Stents | Drug dosages | Aspirin | Stroke | Mortality | Coronary artery | Implantation | Coronary artery disease | Patients | Coronary vessels | Fatalities | Infarction | Acute coronary syndromes | Biosensors | Index Medicus | Abridged Index Medicus
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5. Full Text Rivaroxaban with or without aspirin in patients with stable coronary artery disease: an international, randomised, double-blind, placebo-controlled trial
by Connolly, Stuart J and Eikelboom, John W and Bosch, Jackie and Dagenais, Gilles and Dyal, Leanne and Lanas, Fernando and Metsarinne, Kaj and O'Donnell, Martin and Dans, Anthony L and Ha, Jong-Won and Parkhomenko, Alexandr N and Avezum, Alvaro A and Lonn, Eva and Lisheng, Liu and Torp-Pedersen, Christian and Widimsky, Petr and Maggioni, Aldo P and Felix, Camilo and Keltai, Katalin and Hori, Masatsugu and Yusoff, Khalid and Guzik, Tomasz J and Bhatt, Deepak L and Branch, Kelley R H and Cook Bruns, Nancy and Berkowitz, Scott D and Anand, Sonia S and Varigos, John D and Fox, Keith A A and Yusuf, Salim and SALA, JORGELINA and CARTASEGNA, LUIS and VICO, MARISA and HOMINAL, MIGUEL ANGEL and HASBANI, EDUARDO and CACCAVO, ALBERTO and ZAIDMAN, CESAR and VOGEL, DANIEL and HRABAR, ADRIAN and SCHYGIEL, PABLO OMAR and CUNEO, CARLOS and LUQUEZ, HUGO and MACKINNON, IGNACIO J and AHUAD GUERRERO, RODOLFO ANDRES and COSTABEL, JUAN PABLO and BARTOLACCI, INES PALMIRA and MONTANA, OSCAR and BARBIERI, MARIA and GOMEZ VILAMAJO, OSCAR and GARCIA DURAN, RUBEN OMAR and SCHIAVI, LILIA BEATRIZ and GARRIDO, MARCELO and INGARAMO, ADRIAN and BORDONAVA, ANSELMO PAULINO and PELAGAGGE, MARIA JOSE and NOVARETTO, LEONARDO and ALBISU DI GENNERO, JUAN PABLO and IBANEZ SAGGIA, LUZ MARIA and ALVAREZ, MOIRA and VITA, NESTOR ALEJANDRO and MACIN, STELLA MARIS and DRAN, RICARDO DARIO and CARDONA, MARCELO and GUZMAN, RANDOLPH and GUZMAN, LUIS and SARJANOVICH, RODOLFO JUAN and CUADRADO, JESUS and NANI, SEBASTIAN and LITVAK BRUNO, MARCOS RAUL and CHACON, CAROLINA and MAFFEI, LAURA ELENA and GRINFELD, DIEGO and VENSENTINI, NATALIA and MAJUL, CLAUDIO RODOLFO and LUCIARDI, HECTOR LUCAS and GONZALEZ COLASO, PATRICIA DEL CARMEN and FERRE PACORA, FREDY ANTONI and VAN DEN HEUVEL, PAUL and VERHAMME, PETER and ECTOR, BAVO and DEBONNAIRE, PHILIPPE and VAN DE BORNE, PHILIPPE and LEROY, JEAN and SCHROE, HERMAN and VRANCKX, PASCAL and ELEGEERT, IVAN and HOFFER, ETIENNE and DUJARDIN, KARL and INDIO DO BRASIL, CLARISSE and PRECOMA, DALTON and ABRANTES, JOSE ANTONIO and MANENTI, EULER and REIS, GILMAR and SARAIVA, JOSE and MAIA, LILIA and HERNANDES, MAURO and ROSSI, PAULO and ROSSI DOS SANTOS, FABIO and ZIMMERMANN, SERGIO LUIZ and RECH, RAFAEL and ... and COMPASS Investigators and COMPASS investigators
The Lancet, ISSN 0140-6736, 01/2018, Volume 391, Issue 10117, pp. 205 - 218
Coronary artery disease is a major cause of morbidity and mortality worldwide, and is a consequence of acute thrombotic events involving activation of... 
PREVENTION | MEDICINE, GENERAL & INTERNAL | ORAL RIVAROXABAN | Myocardial Infarction - epidemiology | Cardiovascular Diseases - prevention & control | Humans | Male | Rivaroxaban - administration & dosage | Aspirin - administration & dosage | Factor Xa Inhibitors - administration & dosage | Dose-Response Relationship, Drug | Rivaroxaban - adverse effects | Aspirin - adverse effects | Platelet Aggregation Inhibitors - administration & dosage | Cardiovascular Diseases - mortality | Female | Stroke - epidemiology | Aspirin - therapeutic use | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Rivaroxaban - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Stroke - prevention & control | Double-Blind Method | Drug Administration Schedule | Coronary Artery Disease - drug therapy | Morbidity | Factor Xa Inhibitors - therapeutic use | Factor Xa Inhibitors - adverse effects | Aged | Coronary Artery Disease - epidemiology | Myocardial Infarction - prevention & control | Hemorrhage - chemically induced | Anticoagulants | Aspirin | Stroke | Heart attacks | Mortality | Coronary artery | Clinical trials | Cardiovascular disease | Coronary artery disease | Disease control | Disease prevention | Coronary vessels | Acute coronary syndromes | Thromboembolism | Health risk assessment | Drug therapy | Heart diseases | Index Medicus | Abridged Index Medicus
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6. Full Text 4-Year Clinical Outcomes and Predictors of Repeat Revascularization in Patients Treated With New-Generation Drug-Eluting Stents
by Taniwaki, Masanori, MD and Stefanini, Giulio G., MD and Silber, Sigmund, MD, PhD and Richardt, Gert, MD and Vranckx, Pascal, MD and Serruys, Patrick W., MD, PhD and Buszman, Pawel E., MD and Kelbaek, Henning, MD and Windecker, Stephan, MD and RESOLUTE All-Comers Investigators
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2014, Volume 63, Issue 16, pp. 1617 - 1625
Objectives The aim of the study was to investigate 4-year outcomes and predictors of repeat revascularization in patients treated with the Resolute... 
Cardiovascular | Internal Medicine | everolimus-eluting stent(s) | all-comers population | long-term outcomes | Resolute zotarolimus-eluting stent(s) | drug-eluting stent(s) | DEFINITIONS | CARDIAC & CARDIOVASCULAR SYSTEMS | RANDOMIZED-TRIALS | RESOLUTE | IMPLANTATION | THROMBOSIS | RESTENOSIS | FOLLOW-UP | CORONARY STENTS | Sects | Medical colleges | Angiogenesis inhibitors | Stent (Surgery) | Heart attacks | Cardiology | Stents | Coronary vessels | Clinical outcomes
Journal Article
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