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Nature Immunology, ISSN 1529-2908, 09/2011, Volume 12, Issue 9, pp. 870 - 878
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7508, pp. 184 - 190
Journal Article
Nature, ISSN 0028-0836, 2008, Volume 451, Issue 7175, pp. 211 - 215
Half a century ago, chronic granulomatous disease ( CGD) was first described as a disease fatally affecting the ability of children to survive infections.... 
GAMMA | DENDRITIC CELLS | IDO | TOLERANCE | MULTIDISCIPLINARY SCIENCES | INDOLEAMINE 2,3-DIOXYGENASE | HOST-DEFENSE | INFECTION | DELTA-T-CELLS | NF-KAPPA-B | IL-17 PRODUCTION | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Inflammation - pathology | Reactive Oxygen Species - metabolism | Kynurenine - therapeutic use | T-Lymphocytes - enzymology | Granulomatous Disease, Chronic - metabolism | NADPH Oxidases - metabolism | Granulomatous Disease, Chronic - complications | Tryptophan - metabolism | Lung Diseases, Fungal - microbiology | Inflammation - complications | NADPH Oxidases - deficiency | Inflammation - metabolism | Aspergillosis - pathology | Lung Diseases, Fungal - pathology | Inflammation - drug therapy | Superoxides - metabolism | Aspergillus fumigatus - physiology | NADPH Oxidases - genetics | Kynurenine - metabolism | T-Lymphocytes - pathology | Granulomatous Disease, Chronic - pathology | Aspergillosis - complications | Disease Models, Animal | Lung - pathology | Lung Diseases, Fungal - immunology | Interferon-gamma - therapeutic use | Mice, Inbred C57BL | Lung Diseases, Fungal - complications | Receptors, Antigen, T-Cell, gamma-delta - immunology | Interleukin-17 - deficiency | Mice, Knockout | Interleukin-17 - metabolism | Animals | Interferon-gamma - immunology | Aspergillosis - microbiology | T-Lymphocytes - immunology | Mice | Granulomatous Disease, Chronic - drug therapy | Chronic Disease | Lung - immunology | Aspergillosis - immunology | Complications and side effects | Chronic granulomatous disease | Care and treatment | Metabolic diseases | Inflammation | Research | Risk factors | Biomedical research | Genetic disorders | Immunology | Rodents | Infections | Metabolism | Inflammatory diseases
Journal Article
Immunity, ISSN 1074-7613, 02/2017, Volume 46, Issue 2, pp. 233 - 244
Journal Article
Nature Immunology, ISSN 1529-2908, 11/2002, Volume 3, Issue 11, pp. 1097 - 1101
Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) plays a critical role in peripheral tolerance. However, regulatory pathways initiated by the interactions... 
ALLOGRAFT-REJECTION | DENDRITIC CELLS | INTERFERON-GAMMA | INDOLEAMINE 2,3-DIOXYGENASE | IN-VIVO | T-CELL ACTIVATION | MICE | IMMUNOLOGY | NF-KAPPA-B | CARDIAC ALLOGRAFTS | EXPRESSION | Recombinant Fusion Proteins - pharmacology | Male | NF-kappa B - metabolism | Tryptophan - metabolism | Trans-Activators - physiology | Immunoconjugates - pharmacology | Isoantigens - immunology | p38 Mitogen-Activated Protein Kinases | DNA-Binding Proteins - physiology | NF-kappa B - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | Antigens, Differentiation - physiology | Mice, Knockout | CTLA-4 Antigen | Dendritic Cells - classification | STAT1 Transcription Factor | Cells, Cultured - metabolism | Mice | Mice, Inbred BALB C | Antigens, CD | Immunoconjugates - toxicity | Diabetes Mellitus, Experimental - surgery | Kynurenine - biosynthesis | Recombinant Fusion Proteins - therapeutic use | Abatacept | Immune Tolerance - immunology | Immunoglobulin G - pharmacology | Islets of Langerhans Transplantation | Dendritic Cells - drug effects | Dendritic Cells - metabolism | Immune Tolerance - drug effects | B7-1 Antigen - immunology | Mice, Inbred C57BL | Interferon-gamma - physiology | B7-1 Antigen - metabolism | Enzyme Activation - drug effects | Transplantation, Homologous - immunology | Graft Enhancement, Immunologic | Peptides - pharmacology | Gene Expression Regulation - drug effects | Tryptophan Oxygenase - metabolism | Animals | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Antigen Presentation - drug effects | Pyridines - pharmacology | Graft Survival - drug effects | Interferon-gamma - biosynthesis
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2007, Volume 13, Issue 5, pp. 579 - 586
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, p. 1852
CpG-rich oligodeoxynucleotides activate the immune system, leading to innate and acquired immune responses. The immune-stimulatory effects of CpG-rich... 
PLASMACYTOID DENDRITIC CELLS | IMMUNOSUPPRESSIVE PATHWAY | ACTIVATION | INDOLEAMINE 2,3-DIOXYGENASE IDO | INDUCE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | NF-KAPPA-B | TRYPTOPHAN CATABOLISM | CUTTING EDGE | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Immunomodulation - drug effects | Membrane Glycoproteins - metabolism | Humans | Interferon Regulatory Factors - metabolism | Pneumonia - pathology | NF-kappa B - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Antigens, CD - metabolism | Interleukin-23 - genetics | Signal Transduction - immunology | Interleukin-23 - metabolism | Interferon Type I - metabolism | Pneumonia - immunology | Dendritic Cells - drug effects | Dendritic Cells - metabolism | Immune Tolerance - drug effects | Skin Tests | Toll-Like Receptor 3 - metabolism | Aspergillosis, Allergic Bronchopulmonary - pathology | Toll-Like Receptor 4 - metabolism | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - metabolism | Gene Expression Regulation - drug effects | Animals | Transforming Growth Factor beta - genetics | Signal Transduction - drug effects | Aspergillosis, Allergic Bronchopulmonary - immunology | Mice | Oligodeoxyribonucleotides - pharmacology | Toll-Like Receptor 9 - metabolism | Myeloid Differentiation Factor 88 - metabolism | Transforming Growth Factor beta - metabolism
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 52, pp. 20828 - 20833
Despite their common ability to activate intracellular signaling through CD80/CD86 molecules, cytotoxic T lymphocyte antigen 4 (CTLA-4)-Ig and CD28-Ig bias the... 
T lymphocytes | Messenger RNA | Reactivity | Dendritic cells | Cytokines | Antibodies | Catabolism | Physiological regulation | Immunity | Skin tests | CD28-Ig | Tryptophan catabolism | IL-6 | CD80/86 signaling | SOCS proteins | ACTIVATION | MULTIDISCIPLINARY SCIENCES | COMPETENT DENDRITIC CELLS | CUTTING EDGE | RESPONSES | REJECTION | IN-VIVO | REGULATORY T-CELLS | IMMUNE REGULATION | tryptophan catabolism | NF-KAPPA-B | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Antigens, CD - immunology | B7-2 Antigen - genetics | B7-1 Antigen - genetics | Immune Tolerance - physiology | Dendritic Cells - immunology | Indoleamine-Pyrrole 2,3,-Dioxygenase - immunology | Antigens, CD - genetics | Antigens, CD - metabolism | CD28 Antigens - metabolism | CD28 Antigens - genetics | Mice, Inbred DBA | B7-2 Antigen - immunology | Proteasome Endopeptidase Complex - immunology | Interleukin-6 - genetics | B7-1 Antigen - immunology | Suppressor of Cytokine Signaling Proteins - immunology | Suppressor of Cytokine Signaling Proteins - genetics | Mice, Transgenic | B7-1 Antigen - metabolism | CD28 Antigens - immunology | Ubiquitination - immunology | CTLA-4 Antigen | Proteasome Endopeptidase Complex - genetics | B7-2 Antigen - metabolism | Suppressor of Cytokine Signaling 3 Protein | Animals | Amino Acid Motifs - immunology | Dendritic Cells - enzymology | Interleukin-6 - immunology | Interleukin-6 - biosynthesis | Dendritic Cells - cytology | Mice | Proteasome Endopeptidase Complex - metabolism | Amino Acid Motifs - genetics | Suppressor of Cytokine Signaling Proteins - biosynthesis | Ubiquitination - genetics | Cellular signal transduction | Research | T cells | Properties | Biological Sciences | CD80 | 86 signaling
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2010, Volume 16, Issue 8, pp. 897 - 902
High amounts of glutamate are found in the brains of people with multiple sclerosis, an inflammatory disease marked by progressive demyelination. Glutamate... 
MEDICINE, RESEARCH & EXPERIMENTAL | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | MULTIPLE-SCLEROSIS LESIONS | ACTIVATION | DENDRITIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | T-CELL | TRYPTOPHAN CATABOLISM | CELL BIOLOGY | INFLAMMATION | DIFFERENTIATION | EXPRESSION | TH17 CELLS | Dendritic Cells - immunology | Dendritic Cells - physiology | Encephalomyelitis, Autoimmune, Experimental - immunology | Nerve Degeneration - genetics | Receptors, Metabotropic Glutamate - physiology | Neuroimmunomodulation - physiology | Adaptive Immunity - genetics | Cell Differentiation - genetics | Neuroimmunomodulation - genetics | Receptors, Metabotropic Glutamate - genetics | Encephalitis - metabolism | Encephalomyelitis, Autoimmune, Experimental - genetics | Adaptive Immunity - immunology | Dendritic Cells - metabolism | Encephalitis - genetics | Encephalomyelitis, Autoimmune, Experimental - pathology | Cytokines - metabolism | Glutamic Acid - physiology | Encephalitis - immunology | Multiple Sclerosis - genetics | Nerve Degeneration - immunology | Nerve Degeneration - pathology | Mice, Knockout | Cell Differentiation - immunology | T-Lymphocytes, Helper-Inducer - physiology | Animals | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Signal Transduction - physiology | Glutamic Acid - metabolism | Mice | Multiple sclerosis | Care and treatment | Physiological aspects | Research | T cells | Risk factors | Neurotransmitter receptors | Neurology | Immunology | Cellular biology | Inflammatory diseases
Journal Article