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Chemical science (Cambridge), ISSN 2041-6520, 2/2018, Volume 9, Issue 7, pp. 174 - 1752
Misfolding of proteins is the basis of several proteinopathies. Chemical and pharmacological chaperones are small molecules capable of inducing the correct... 
Proteins | Pharmacology
Journal Article
08/2017, 1st, ISBN 3527342052, 350
The past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products cover... 
Enzymes | Bioactive compounds | Enzymes--Effect of drugs on | Natural products--Therapeutic use | Natural products
eBook
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e72203
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 03/2018, Volume 19, Issue 3, p. 644
...International Journal of Molecular Sciences Editorial Insights into Natural Products in Inflammation Paula B. Andrade ID and Patrícia Valentão * ID REQUIMTE... 
RESVERATROL | RESPONSES | OXIDATIVE STRESS | IN-VITRO | ACTIVATION | LACTOFERRIN | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISEASE | EXTRACTS | EXPRESSION | CHEMISTRY, MULTIDISCIPLINARY | Natural products | n/a
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 07/2015, Volume 16, Issue 8, pp. 17696 - 17718
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, p. e88341
..., Porto, Portugal, IBMC –Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal Patrícia Valentão Affiliation: REQUIMTE/Laboratório de... 
CELLS | PATHWAY | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | CAROTENOIDS | TARGETS | ENDOPLASMIC-RETICULUM STRESS | EXPRESSION | CANCER | OXIDE-INDUCED APOPTOSIS | INNATE IMMUNITY | Transcription Factor CHOP - genetics | Ergosterol - isolation & purification | Fatty Acids, Monounsaturated - pharmacology | Fatty Acids, Monounsaturated - isolation & purification | NF-kappa B - metabolism | Lipopolysaccharides - antagonists & inhibitors | Endoplasmic Reticulum Stress - genetics | Ergosterol - analogs & derivatives | Cyclooxygenase 2 - genetics | Ergosterol - pharmacology | Anti-Inflammatory Agents - isolation & purification | Interleukin-6 - metabolism | Cell Line | NF-kappa B - antagonists & inhibitors | Endoplasmic Reticulum Stress - drug effects | Interleukin-6 - genetics | Signal Transduction | Anti-Inflammatory Agents - pharmacology | Gene Expression Regulation | Macrophages - cytology | Drug Synergism | Macrophages - metabolism | Animals | NF-kappa B - genetics | Nitric Oxide Synthase Type II - genetics | Cyclooxygenase 2 - metabolism | Lipopolysaccharides - pharmacology | Starfish - chemistry | Macrophages - drug effects | Inflammation - prevention & control | Mice | Transcription Factor CHOP - metabolism | Nitric Oxide Synthase Type II - metabolism | NF-κB protein | Inflammation | Gene expression | Fatty acids | Anti-inflammatory agents | Nitric-oxide synthase | Lipopolysaccharides | Interleukin 6 | Proteins | Sterols | Metabolites | Natural products | Rodents | Nitric oxide | Cyclooxygenase-2 | Endoplasmic reticulum | Apoptosis
Journal Article
Plant Physiology, ISSN 0032-0889, 8/2016, Volume 171, Issue 4, pp. 2371 - 2378
Idioblasts from Catharanthus roseus leaves specifically accumulate alkaloids and show autofluorescence that enabled the fluorescence-activated cell sorting of... 
Research Report
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 01/2018, Volume 19, Issue 1, p. 186
Journal Article
Arabian Journal of Chemistry, ISSN 1878-5352, 01/2020, Volume 13, Issue 1, pp. 45 - 58
Kelps play a key role in coastal ecosystems and exhibit great potential as feedstock of valuable compounds with potential biotechnological applications. This... 
Marine environment | Gas chromatography/ion trap-mass spectrometry | Gas chromatography-flame ionization detector | Kelps | Fatty acids | Integrated multi-trophic aquaculture | DEFENSE | COAST | MARINE MACROALGAE | SEASONAL-VARIATION | CHEMISTRY, MULTIDISCIPLINARY | TEMPERATURE | CHEMICAL-COMPOSITION | ALGAE | DERIVATIVES | BROWN | LIPIDS
Journal Article
Molecules, ISSN 1420-3049, 01/2017, Volume 22, Issue 1, p. 56
...molecules Review Phlorotannins: Towards New Pharmacological Interventions for Diabetes Mellitus Type 2 Graciliana Lopes, Paula B. Andrade and Patrícia Valentão... 
Pancreatic β-Cells | Hyperglycaemia | α-Glucosidase | Advanced Glycation End-Products | Glucotoxicity | Diabetes Mellitus | Postprandial Glucose | Phlorotannins | REDUCING OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | POTENT ALPHA-GLUCOSIDASE | pancreatic beta-cells | ALDOSE REDUCTASE INHIBITOR | diabetes mellitus | glucotoxicity | advanced glycation end-products | AMYLASE-INHIBITORY-ACTIVITIES | CHEMISTRY, MULTIDISCIPLINARY | phlorotannins | postprandial glucose | ISHIGE-OKAMURAE | alpha-glucosidase | ECKLONIA-CAVA PROTECTS | hyperglycaemia | ALLEVIATES POSTPRANDIAL HYPERGLYCEMIA | BROWN ALGA | GLYCATION END-PRODUCTS | Hypoglycemic Agents - therapeutic use | alpha-Amylases - antagonists & inhibitors | Polyphenols - isolation & purification | Humans | Tannins - therapeutic use | Glycation End Products, Advanced - antagonists & inhibitors | alpha-Amylases - metabolism | Diabetes Mellitus, Type 2 - metabolism | Hyperglycemia - drug therapy | Phaeophyta - chemistry | Hyperglycemia - metabolism | Hypoglycemic Agents - isolation & purification | Insulin-Secreting Cells - metabolism | Insulin-Secreting Cells - drug effects | Glycation End Products, Advanced - metabolism | Tannins - isolation & purification | Hyperglycemia - pathology | Diabetes Mellitus, Type 2 - pathology | Insulin-Secreting Cells - pathology | Polyphenols - therapeutic use | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Seaweed - chemistry | alpha-Glucosidases - metabolism | Deregulation | Toxicity | Diabetes mellitus | Homeostasis | Pharmacology | Glucose | Seaweeds | Side effects | Hyperglycemia | Polyphenols | Biocompatibility | Product development | Diabetes | Drug discovery | Metabolic disorders | pancreatic β-cells | α-glucosidase
Journal Article