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The New England Journal of Medicine, ISSN 0028-4793, 09/2014, Volume 371, Issue 11, pp. 1005 - 1015
About 25% of young adults with ALL have Ph-like genotypes, which are associated with poor outcomes with conventional treatment. In this gene-expression study,... 
MEDICINE, GENERAL & INTERNAL | MODELS | B-CELL PRECURSOR | INHIBITOR THERAPY | IMATINIB | PEDIATRIC ACUTE LEUKEMIAS | GENE FUSION | EXPRESSION | ETV6-NTRK3 FUSION TRANSCRIPTS | CRLF2 | DELETION | Oligonucleotide Array Sequence Analysis | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Humans | Child, Preschool | Infant | Male | Young Adult | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Heterografts | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - mortality | Adult | Female | DNA, Neoplasm - analysis | Receptors, Cytokine - metabolism | Child | Philadelphia Chromosome | Receptors, Cytokine - genetics | Signal Transduction - genetics | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Protein Kinase Inhibitors - therapeutic use | Adolescent | Survival Analysis | Mice | Polymorphism, Single Nucleotide | Genome, Human | Protein-Tyrosine Kinases - antagonists & inhibitors | Development and progression | Care and treatment | Genetic aspects | Research | Lymphocytic leukemia | Tyrosine metabolism | Cell proliferation | Adolescence | Tyk2 protein | Leukemia | Genes | Clinical trials | Oncology | Genomes | Kinases | Cell activation | Janus kinase 2 | Xenografts | Teenagers | Children | Protein-tyrosine kinase | Age | Tyrosine | Young adults | Genomic analysis | Acute lymphatic leukemia | Stat5 protein | Lymphatic leukemia | Gene expression | Philadelphia chromosome | Interleukin 7 receptors | Thymic stromal lymphopoietin | Lymphocytes B | Cell lines | Index Medicus | Abridged Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 12/2013, Volume 24, Issue 6, pp. 710 - 724
Journal Article
by Ménard, Sandie and Ménard, Didier and Khim, Nimol and Beghain, Johann and Adegnika, Ayola A and Shafiul-Alam, Mohammad and Amodu, Olukemi and Rahim-Awab, Ghulam and Barnadas, Céline and Berry, Antoine and Boum, Yap and Bustos, Maria D and Cao, Jun and Chen, Jun-Hu and Collet, Louis and Cui, Liwang and Thakur, Garib-Das and Dieye, Alioune and Djallé, Djibrine and Dorkenoo, Monique A and Eboumbou-Moukoko, Carole E and Espino, Fe-Esperanza-Caridad J and Fandeur, Thierry and Ferreira-da-Cruz, Maria-Fatima and Fola, Abebe A and Fuehrer, Hans-Peter and Hassan, Abdillahi M and Herrera, Socrates and Hongvanthong, Bouasy and Houzé, Sandrine and Ibrahim, Maman L and Jahirul-Karim, Mohammad and Jiang, Lubin and Kano, Shigeyuki and Ali-Khan, Wasif and Khanthavong, Maniphone and Kremsner, Peter G and Lacerda, Marcus and Leang, Rithea and Leelawong, Mindy and Li, Mei and Lin, Khin and Mazarati, Jean-Baptiste and Morlais, Isabelle and Muhindo-Mavoko, Hypolite and Musset, Lise and Na-Bangchang, Kesara and Nambozi, Michael and Niaré, Karamoko and Noedl, Harald and Ouédraogo, Jean-Bosco and Pillai, Dylan R and Pradines, Bruno and Quang-Phuc, Bui and Ramharter, Michael and Randrianarivelojosia, Milijaona and Sattabongkot, Jetsumon and Sheikh-Omar, Abdiqani and Silué, Kigbafori D and Sirima, Sodiomon B and Sutherland, Colin and Syafruddin, Din and Tahar, Rachida and Tang, Lin-Hua and Touré, Offianan A and Tshibangu-wa-Tshibangu, Patrick and Vigan-Womas, Inès and Warsame, Marian and Wini, Lyndes and Zakeri, Sedigheh and Kim, Saorin and Eam, Rotha and Berne, Laura and Khean, Chanra and Chy, Sophy and Ken, Malen and Loch, Kaknika and Canier, Lydie and Duru, Valentine and Legrand, Eric and Barale, Jean-Christophe and Stokes, Barbara and Straimer, Judith and Witkowski, Benoit and Fidock, David A and Rogier, Christophe and Ringwald, Pascal and Ariey, Frederic and Mercereau-Puijalon, Odile and KARMA Consortium
The New England Journal of Medicine, ISSN 0028-4793, 06/2016, Volume 374, Issue 25, pp. 2453 - 2464
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, pp. e82513 - e82513
Neuroblastoma is an embryonal tumor of childhood with a heterogenous clinical presentation that reflects differences in activation of complex biological... 
VANDETANIB ZD6474 | MAMMALIAN TARGET | PHOSPHATIDYLINOSITOL 3-KINASE/AKT | RETINOIC ACID | 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE-1 | MULTIDISCIPLINARY SCIENCES | THERAPEUTIC TARGET | PEDIATRIC-PATIENTS | MASS-SPECTROMETRY | GROWTH-FACTOR-I | SMALL-MOLECULE INHIBITOR | Cell Survival - drug effects | Receptor, IGF Type 1 - metabolism | Receptor, IGF Type 1 - antagonists & inhibitors | Signal Transduction | Humans | Molecular Sequence Annotation | Neuroblastoma - genetics | Proteome | Phosphoproteins - genetics | Phosphoproteins - metabolism | Receptor, Insulin - antagonists & inhibitors | raf Kinases - metabolism | Phosphatidylinositol 3-Kinases | MAP Kinase Signaling System | Protein Interaction Maps | Cell Line, Tumor | Receptor, Insulin - metabolism | Neuroblastoma - metabolism | Protein Kinase Inhibitors - pharmacology | Proteomics - methods | Proto-Oncogene Proteins c-akt - metabolism | Neural Stem Cells - metabolism | Proto-Oncogene Proteins c-ret - antagonists & inhibitors | Proto-Oncogene Proteins c-ret - genetics | Tyrosine | Cellular signal transduction | Fibroblast growth factors | Neuroblastoma | Protein kinases | TOR protein | Pediatrics | Fibroblast growth factor | Phosphorylation | Peptides | AKT protein | Oncology | Biology | Insulin-like growth factors | Kinases | Proteins | Signal transduction | Cell growth | Ret protein | Pathways | Cell cycle | Infrared radiation | Protein-tyrosine kinase receptors | Modelling | Children | Fibroblast growth factor receptor 1 | Protein-tyrosine kinase | Medical research | Cell survival | Hematology | Gene expression | Insulin | Neural crest | 1-Phosphatidylinositol 3-kinase | Medicine | Studies | Signaling | Hypotheses | Gene amplification | Medical prognosis | Signal processing | Transduction | Mutation | Tumors | Cancer | Index Medicus
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 03/2015, Volume 135, Issue 3, pp. 816 - 823
Journal Article
Nature Genetics, ISSN 1061-4036, 2016, Volume 48, Issue 12, pp. 1481 - 1489
Journal Article