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European Journal of Clinical Pharmacology, ISSN 0031-6970, 1987, Volume 33, Issue 3, pp. 237 - 242
Journal Article
Journal of chromatography, 11/1977, Volume 142, p. 611
A sensitive and selective method for the determination of the quaternary ammonium compound oxyphenonium bromide (Antrenyl), a drug with strong anticholinergic... 
Quaternary Ammonium Compounds - analysis | Chromatography, Gas - methods | Chromatography, Ion Exchange | Oxyphenonium - analysis | Oxyphenonium - blood | Animals | Humans | Oxyphenonium - urine
Journal Article
Journal Article
Clinical Pharmacology and Therapeutics, ISSN 0009-9236, 04/1977, Volume 21, Issue 4, pp. 457 - 463
Bioavailability after oral administration of the anticholinergic drug thiazinamium methylsulfate (Multergan), a phenothiazine derivative with a quaternary... 
Promethazine - metabolism | Administration, Oral | Humans | Promethazine - analogs & derivatives | Bis-Trimethylammonium Compounds - metabolism | Adult | Biological Availability | Male | Promethazine - administration & dosage | Injections, Intramuscular
Journal Article
Pharmaceutisch Weekblad Scientific Edition, ISSN 0167-6555, 10/1982, Volume 4, Issue 5, pp. 122 - 128
The quaternary ammonium compound thiazinamium was found to be metabolized by sulfoxidation solely. No ring hydroxylation products, nor demethylation products... 
Promethazine - metabolism | Injections, Intravenous | Time Factors | Biotransformation | Humans | Promethazine - analogs & derivatives | Bile - metabolism | Male | Promethazine - administration & dosage | Injections, Intramuscular
Journal Article
Pharmaceutisch Weekblad Scientific Edition, ISSN 0167-6555, 10/1982, Volume 4, Issue 5, pp. 129 - 134
In this study it is shown that biotransformation of thiazinamium, when given orally, does not differ qualitatively from the pattern found after parenteral... 
Suppositories | Administration, Oral | Humans | Middle Aged | Bile - metabolism | Male | Promethazine - metabolism | Time Factors | Promethazine - analogs & derivatives | Adolescent | Rectum | Adult | Female | Promethazine - administration & dosage
Journal Article
Pharmaceutisch weekblad, ISSN 0031-6911, 12/1979, Volume 1, Issue 1, pp. 940 - 944
In this study we have investigated to what extent the concept of ‘ion pair’ absorption is valid after administering the quaternary ammonium ion thiazinamium... 
Medicine & Public Health | Internal Medicine | Pharmacy
Journal Article
The Journal of pharmacy and pharmacology, ISSN 0022-3573, 11/1975, Volume 27, Issue 11, p. 849
A sensitive and selective method for the quantitative determination of the quaternary ammonium antiacetylcholine-compound thiazinamium methylsulphate... 
Quaternary Ammonium Compounds - analysis | Promethazine - blood | Quaternary Ammonium Compounds - urine | Promethazine - analogs & derivatives | Chromatography, Gas | Promethazine - urine | Methods | Quaternary Ammonium Compounds - blood | Hydrogen-Ion Concentration
Journal Article
Pharmaceutisch weekblad, ISSN 0031-6911, 12/1979, Volume 1, Issue 1, pp. 937 - 940
In order to investigate whether administration of an otherwise poorly absorbed drug as an ion pair would improve bioavailability, the disposition of the... 
Medicine & Public Health | Internal Medicine | Pharmacy
Journal Article
International Journal of Clinical Pharmacology Therapy and Toxicology, ISSN 0174-4879, 1983, Volume 21, Issue 9, pp. 454 - 459
The disposition of the quaternary ammonium compound thiazinamium methyl sulfate is described after intramuscular injection in humans. The plasma... 
Promethazine - metabolism | Humans | Middle Aged | Promethazine - analogs & derivatives | Adolescent | Half-Life | Adult | Male | Promethazine - administration & dosage | Injections, Intramuscular | Kinetics
Journal Article
by Fuchsberger, Christian and Flannick, Jason and Teslovich, Tanya M and Mahajan, Anubha and Agarwala, Vineeta and Gaulton, Kyle J and Ma, Clement and Fontanillas, Pierre and Moutsianas, Loukas and McCarthy, Davis J and Rivas, Manuel A and Perry, John R. B and Sim, Xueling and Blackwell, Thomas W and Robertson, Neil R and Rayner, N. William and Cingolani, Pablo and Locke, Adam E and Fernandez Tajes, Juan and Highland, Heather M and Dupuis, Josee and Chines, Peter S and Lindgren, Cecilia M and Hartl, Christopher and Jackson, Anne U and Chen, Han and Huyghe, Jeroen R and van de Bunt, Martijn and Pearson, Richard D and Kumar, Ashish and Müller-Nurasyid, Martina and Grarup, Niels and Stringham, Heather M and Gamazon, Eric R and Lee, Jaehoon and Chen, Yuhui and Scott, Robert A and Below, Jennifer E and Chen, Peng and Huang, Jinyan and Go, Min Jin and Stitzel, Michael L and Pasko, Dorota and Parker, Stephen C. J and Varga, Tibor V and Green, Todd and Beer, Nicola L and Day-Williams, Aaron G and Ferreira, Teresa and Fingerlin, Tasha and Horikoshi, Momoko and Hu, Cheng and Huh, Iksoo and Ikram, Mohammad Kamran and Kim, Bong-Jo and Kim, Yongkang and Kim, Young Jin and Kwon, Min-Seok and Lee, Juyoung and Lee, Selyeong and Lin, Keng-Han and Maxwell, Taylor J and Nagai, Yoshihiko and Wang, Xu and Welch, Ryan P and Yoon, Joon and Zhang, Weihua and Barzilai, Nir and Voight, Benjamin F and Han, Bok-Ghee and Jenkinson, Christopher P and Kuulasmaa, Teemu and Kuusisto, Johanna and Manning, Alisa and Ng, Maggie C. Y and Palmer, Nicholette D and Balkau, Beverley and Stancáková, Alena and Abboud, Hanna E and Boeing, Heiner and Gieaitis, Vilmantas and Prabhakaran, Dorairaj and Gottesman, Omri and Scott, James and Carey, Jason and Kwan, Phoenix and Grant, George and Smith, Joshua D and Neale, Benjamin M and Purcell, Shaun and Butterworth, Adam S and Howson, Joanna M. M and Lee, Heung Man and Lu, Yingchang and Kwak, Soo-Heon and Zhao, Wei and Danesh, John and Lam, Vincent K. L and Park, Kyong Soo and Saleheen, Danish and ... and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2016, Volume 536, Issue 7614, pp. 41 - +
Journal Article
Nature, ISSN 0028-0836, 2004, Volume 432, Issue 7018, pp. 695 - 716
We present here a draft genome sequence of the red jungle fowl, Gallus gallus. Because the chicken is a modern descendant of the dinosaurs and the first... 
phylogenetic analysis | mammalian evolution | tissue-specific genes | brown-norway rat | non-ltr retrotransposons | major histocompatibility complex | olfactory receptor | mouse genome | recent segmental duplications | alcohol-dehydrogenase | MOUSE GENOME | NON-LTR RETROTRANSPOSONS | ALCOHOL-DEHYDROGENASE | PHYLOGENETIC ANALYSIS | MULTIDISCIPLINARY SCIENCES | BROWN-NORWAY RAT | RECENT SEGMENTAL DUPLICATIONS | MAJOR HISTOCOMPATIBILITY COMPLEX | TISSUE-SPECIFIC GENES | OLFACTORY RECEPTOR | MAMMALIAN EVOLUTION | Gene Duplication | Multigene Family - genetics | Conserved Sequence - genetics | Vertebrates - genetics | Physical Chromosome Mapping | Genomics | Humans | Long Interspersed Nucleotide Elements - genetics | Mutagenesis - genetics | Synteny | Genes - genetics | Short Interspersed Nucleotide Elements - genetics | RNA, Untranslated - genetics | Sequence Analysis, DNA | Pseudogenes - genetics | Animals | Retroviridae - genetics | DNA Transposable Elements - genetics | Chickens - genetics | Genome | Avian Proteins - genetics | Evolution, Molecular | Birds | Evolution | Genetic diversity | Gene expression | Mammals | Chromosomes | Research Support; U.S. Gov't; P.H.S | Research Support; U.S. Gov't; Non-P.H.S | Comparative Study | Long Interspersed Nucleotide Elements/genetics | Biology | Avian Proteins/genetics | Vertebrates/genetics | Short Interspersed Nucleotide Elements/genetics | Pseudogenes/genetics | Genetics | Research Support; Non-U.S. Gov't | Biologi | Natural Sciences | Biological Sciences | RNA; Untranslated/genetics | Mutagenesis/genetics | DNA Transposable Elements/genetics | Multigene Family/genetics | Retroviridae/genetics | Sequence Analysis; DNA | Genetik | Genes/genetics | Naturvetenskap | Conserved Sequence/genetics | Evolution; Molecular | Biologiska vetenskaper | Cell and molecular biology | Chickens/genetics | Cell- och molekylärbiologi
Journal Article
by Marouli, Eirini and Graff, Mariaelisa and Medina-Gomez, Carolina and Lo, Ken Sin and Wood, Anew R and Kjaer, Troels R and Fine, Rebecca S and Lu, Yingchang and Schurmann, Claudia and Highland, Heather M and Rüeger, Sina and Thorleifsson, Gudmar and Justice, Anne E and Lamparter, David and Stirrups, Kathleen E and Turcot, Valérie and Young, Kristin L and Winkler, Thomas W and Esko, Tõnu and Karaderi, Tugce and Locke, Adam E and Masca, Nicholas G. D and Ng, Maggie C. Y and Mudgal, Poorva and Rivas, Manuel A and Vedantam, Sailaja and Mahajan, Anubha and Guo, Xiuqing and Abecasis, Goncalo and Aben, Katja K and Adair, Linda S and Alam, Dewan S and Albrecht, Eva and Allin, Kristine H and Allison, Matthew and Amouyel, Philippe and Appel, Emil V and Arveiler, Dominique and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Banas, Bernhard and Bang, Lia E and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bonnycastle, Lori L and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Burt, Amber A and Butterworth, Adam S and Carey, David J and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Auey Y and Cocca, Massimiliano and Collins, Francis S and Cook, James P and Corley, Janie and Galbany, Jordi Corominas and Cox, Amanda J and Cuellar-Partida, Gabriel and Danesh, John and Davies, Gail and de Bakker, Paul I. W and de Borst, Gert J and de Denus, Simon and de Groot, Mark C. H and de Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and den Hollander, Anneke I and Dennis, Joe G and Di Angelantonio, Emanuele and nos, Fotios and Du, Mengmeng and Dunning, Alison M and Easton, Douglas F and Ebeling, Tapani and Edwards, Todd L and Ellinor, Patrick T and Elliott, Paul and Evangelou, Evangelos and Farmaki, Aliki-Eleni and Faul, Jessica D and ... and EPIC-CVD Consortium and GoT2D Genes Consortium and MAGIC Investigators and Global Lipids Genetics Consortium and EPIC-InterAct Consortium and ReproGen Consortium and ExomeBP Consortium and CHD Exome Consortium and T2D-Genes Consortium and The EPIC-InterAct Consortium and CHD Exome+ Consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Allmänmedicin and Umeå universitet and Medicin
Nature, ISSN 0028-0836, 2017, Volume 542, Issue 7640, pp. 186 - 190
Journal Article