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Gastroenterology, ISSN 0016-5085, 2003, Volume 124, Issue 7, pp. 1774 - 1785
Journal Article
Current Colorectal Cancer Reports, ISSN 1556-3790, 12/2015, Volume 11, Issue 6, pp. 298 - 302
In the treatment of metastatic colorectal cancer, chemotherapy is used as a backbone to which an angiogenesis inhibitor such as bevacizumab (vascular... 
RAS | Panitumumab | Oncology | Exon 2 | Bevacizumab | FOLFIRI | Medicine & Public Health | Colorectal Surgery | KRAS | Cetuximab | FOLFOX | Metastatic colorectal cancer | Proctology | Chemotherapy | Comorbidity | Colorectal cancer | Monoclonal antibodies | Metastasis | Angiogenesis inhibitors | Drug therapy | Vascular endothelial growth factor | Cancer
Journal Article
Gut, ISSN 0017-5749, 2007, Volume 56, Issue 4, pp. 509 - 517
Journal Article
Journal of rheumatology, ISSN 0315-162X, 2005, Volume 32, Issue Suppl. 74, pp. 26 - 30
Crohn's disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract of unknown origin. Therapies include immune modulating agents, biological... 
Crohn's disease | Etanercept | Infliximab | Tumor necrosis factor | Apoptosis | CELLS | tumor necrosis factor | PATHWAY | etanercept | infliximab | RESISTANCE | apoptosis | ALPHA | MONOCLONAL-ANTIBODY CA2 | RHEUMATOLOGY
Journal Article
Gastroenterology, ISSN 0016-5085, 01/2004, Volume 126, Issue 1, pp. 111 - 121
Background & Aims: The recent findings of bone morphogenetic protein (BMP) receptor la mutations in juvenile polyposis and frequent Smad4 mutations in colon... 
I RECEPTORS | CADHERIN | APOPTOSIS | GROWTH-FACTOR-BETA | SMAD PROTEINS | CANCER CELLS | MOUSE | GERMLINE MUTATIONS | JUVENILE POLYPOSIS | INDUCTION | GASTROENTEROLOGY & HEPATOLOGY | Bone Morphogenetic Proteins - antagonists & inhibitors | Intestinal Mucosa - metabolism | Intestinal Mucosa - physiopathology | Cytoskeletal Proteins - antagonists & inhibitors | Apoptosis - drug effects | Humans | Colonic Neoplasms - metabolism | Colonic Neoplasms - physiopathology | DNA-Binding Proteins - metabolism | Bone Morphogenetic Proteins - metabolism | Bone Morphogenetic Protein Receptors, Type I | Colon - physiopathology | Bone Morphogenetic Proteins - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Transforming Growth Factor beta | Carrier Proteins | beta Catenin | Bone Morphogenetic Protein 2 | Smad4 Protein | Bone Morphogenetic Protein Receptors, Type II | Cell Division - drug effects | Colon - metabolism | Adenomatous Polyposis Coli - metabolism | Animals | Cell Differentiation - drug effects | Smad1 Protein | Smad Proteins | Bone Morphogenetic Protein Receptors | Cell Line, Tumor | Trans-Activators - metabolism | Mice | Proteins - pharmacology | Trans-Activators - antagonists & inhibitors | Receptors, Growth Factor - metabolism | Immunohistochemistry | Bone morphogenetic proteins | Cellular signal transduction | Colon cancer | Transforming growth factors | Index Medicus | Abridged Index Medicus
Journal Article
American journal of clinical nutrition, ISSN 0002-9165, 2004, Volume 80, Issue 6, pp. 1618 - 1625
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 02/2016, Volume 34, Issue 4, pp. 696 - 696
Conference Proceeding
by Palles, Claire and Chegwidden, Laura and Li, Xinzhong and Findlay, John M and Farnham, Garry and Castro Giner, Francesc and Peppelenbosch, Maikel P and Kovac, Michal and Adams, Claire L and Prenen, Hans and Briggs, Sarah and Harrison, Rebecca and Sanders, Scott and MacDonald, David and Haigh, Chris and Tucker, Art and Love, Sharon and Nanji, Manoj and Decaestecker, John and Ferry, David and Rathbone, Barrie and Hapeshi, Julie and Barr, Hugh and Moayyedi, Paul and Watson, Peter and Zietek, Barbara and Maroo, Neera and Gay, Laura and Underwood, Tim and Boulter, Lisa and McMurtry, Hugh and Monk, David and Patel, Praful and Ragunath, Krish and Al Dulaimi, David and Murray, Iain and Koss, Konrad and Veitch, Anew and Trudgill, Nigel and Nwokolo, Chuka and Rembacken, Bjorn and Atherfold, Paul and Green, Elaine and Ang, Yeng and Kuipers, Ernst J and Chow, Wu and Paterson, Stuart and Kai, Sudarshan and Beales, Ian and Grimley, Charles and Mullins, Paul and Beckett, Conrad and Farrant, Mark and Dixon, Anew and Kelly, Sean and Johnson, Matthew and Wajed, Shahjehan and Dhar, Anjan and Sawyer, Elinor and Roylance, Rebecca and Onstad, Lynn and Gammon, Marilie D and Corley, Douglas A and Shaheen, Nicholas J and Bird, Nigel C and Hardie, Laura J and Reid, Brian J and Ye, Weimin and Liu, Geoffrey and Romero, Yvonne and Bernstein, Leslie and Wu, Anna H and Casson, Alan G and Fitzgerald, Rebecca and Whiteman, David C and Risch, Harvey A and Levine, David M and Vaughan, Tom L and Verhaar, Auke P and van den Brande, Jan and Toxopeus, Eelke L and Spaander, Manon C and Wijnhoven, Bas P. L and van der Laan, Luc J. W and Krishnadath, Kausilia and Wijmenga, Cisca and Trynka, Gosia and McManus, Ross and Reynolds, John V and O'Sullivan, Jacintha and MacMathuna, Paaic and McGarrigle, Sarah A and Kelleher, Dermot and Vermeire, Severine and Cleynen, Isabelle and Bisschops, Raf and Tomlinson, Ian and Jankowski, Janusz
Gastroenterology, ISSN 0016-5085, 2015, Volume 148, Issue 2, pp. 367 - 378
Journal Article
Gastroenterology, ISSN 0016-5085, 2011, Volume 140, Issue 7, pp. 1887 - 1894
Journal Article
European journal of gastroenterology & hepatology, ISSN 0954-691X, 2016, Volume 28, Issue 9, pp. 1065 - 1072
Journal Article
Journal Article
Investigational New Drugs, ISSN 0167-6997, 10/2014, Volume 32, Issue 5, pp. 995 - 1004
Background: ASP9521 is a first-in-class orally available inhibitor of the enzyme 17 β-hydroxysteroid dehydrogenase type 5 (17 βHSD5; AKR1C3), catalysing the... 
Castration-resistant prostate cancer | Testosterone | Androgen deprivation therapy | Medicine & Public Health | Androgen synthesis | AKR1C3 | Oncology | Pharmacology/Toxicology | 17beta-hydroxysteroid dehydrogenase type 5 | ONCOLOGY | DEPRIVATION | GUIDELINES | RECEPTOR | PHARMACOLOGY & PHARMACY | DIHYDROTESTOSTERONE | Cell Count | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Prostatic Neoplasms, Castration-Resistant - pathology | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Piperidines - pharmacology | Antineoplastic Agents - adverse effects | Dihydrotestosterone - blood | Indoles - pharmacology | Piperidines - pharmacokinetics | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Kallikreins - blood | Testosterone - blood | Androgen Antagonists - pharmacokinetics | Prostatic Neoplasms, Castration-Resistant - blood | Androgen Antagonists - pharmacology | Treatment Outcome | Prostatic Neoplasms, Castration-Resistant - drug therapy | Prostate-Specific Antigen - blood | Hydroxyprostaglandin Dehydrogenases - antagonists & inhibitors | Indoles - adverse effects | Aldo-Keto Reductase Family 1 Member C3 | Piperidines - therapeutic use | Piperidines - adverse effects | Androgen Antagonists - therapeutic use | Indoles - pharmacokinetics | Indoles - therapeutic use | Aged | Androgen Antagonists - adverse effects | Complications and side effects | Care and treatment | Patient outcomes | Androgen suppression therapy | Research | Prostate cancer | Health aspects | Studies | Androgens | Analysis | Pharmacology | Metastasis | Cancer therapies | Index Medicus
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 05/2017, Volume 35, Issue 15_suppl, pp. e18208 - e18208
Conference Proceeding
Journal Article