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International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 02/2015, Volume 91, Issue 2, pp. 351 - 359
Purpose Several individual clinical and preclinical studies have shown the possibility of evaluating tumor hypoxia by using noninvasive positron emission... 
Radiology | Hematology, Oncology and Palliative Medicine | LUNG-CANCER | HEAD | ONCOLOGY | SQUAMOUS-CELL CARCINOMA | CHEMORADIOTHERAPY | BIODISTRIBUTION | F-18-FLUOROMISONIDAZOLE | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | NECK-CANCER | REPRODUCIBILITY | RADIATION-THERAPY | Reproducibility of Results | Radiopharmaceuticals - pharmacokinetics | Rhabdomyosarcoma - metabolism | Rats | Rhabdomyosarcoma - pathology | Misonidazole - pharmacokinetics | Imidazoles - pharmacokinetics | Misonidazole - analogs & derivatives | Positron-Emission Tomography - methods | Rhabdomyosarcoma - diagnostic imaging | Oxygen - metabolism | Cell Hypoxia | Animals | Models, Biological | Computer Simulation | Sensitivity and Specificity | Cell Line, Tumor | Triazoles - pharmacokinetics | Nitroimidazoles - pharmacokinetics | PET imaging | Tracers (Biology) | Comparative analysis | Developmental biology | Tumors | Index Medicus | NEOPLASMS | BIOMEDICAL RADIOGRAPHY | NICOTINAMIDE | SENSITIVITY | CORRELATIONS | COMPARATIVE EVALUATIONS | CAT SCANNING | OXYGEN | MODIFICATIONS | ANOXIA | INJECTION | POSITRON COMPUTED TOMOGRAPHY | RESPIRATION | UPTAKE | RADIOLOGY AND NUCLEAR MEDICINE | FLUORINE 18 | BLOOD | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, pp. e82331 - e82331
Brain cancer is a devastating disease affecting many people worldwide. Effective treatment with chemotherapeutics is limited due to the presence of the... 
MALIGNANT GLIOMA | CELLS | TRANSPORT | MULTIDISCIPLINARY SCIENCES | BARRIER | METASTASES | ADRIAMYCIN | BIODISTRIBUTION | MODEL | CHEMOTHERAPY | PACLITAXEL | Doxorubicin - blood | Glutathione - pharmacokinetics | Doxorubicin - therapeutic use | Capillaries - pathology | Humans | Brain Neoplasms - pathology | Body Weight - drug effects | Polyethylene Glycols - therapeutic use | Drug Delivery Systems | Brain - blood supply | Glutathione - pharmacology | Time Factors | Doxorubicin - analogs & derivatives | Female | Polyethylene Glycols - pharmacology | Glutathione - therapeutic use | Tissue Distribution - drug effects | Glutathione - analogs & derivatives | Endothelial Cells - metabolism | Polyethylene Glycols - pharmacokinetics | Treatment Outcome | Brain Neoplasms - drug therapy | Doxorubicin - pharmacokinetics | Brain - drug effects | Animals | Mice, Nude | Glioblastoma - pathology | Survival Analysis | Brain - pathology | Cell Proliferation - drug effects | Mice | Brain Neoplasms - ultrastructure | Endothelial Cells - pathology | Glioblastoma - drug therapy | Doxorubicin - pharmacology | Glutathione - blood | Drugs | Plasma physics | Drug delivery systems | Anthracyclines | Thiols | Gliomas | Brain tumors | Drug therapy | Cancer | Vehicles | Nuclear medicine | Bioluminescence | Neurosciences | Brain cancer | Glioblastoma | Drug delivery | Metastasis | Cancer therapies | Doxorubicin | Antioxidants | Blood-brain barrier | Inhibition | Xenobiotics | Glutathione | Medical treatment | Pharmacology | Breast cancer | Disease control | Endothelial cells | Studies | Chemotherapy | Brain research | Diffusion barriers | Medical prognosis | Pharmacokinetics | Tumors | Index Medicus
Journal Article
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 2010, Volume 37, Issue 2, pp. 250 - 259
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2011, Volume 108, Issue 35, pp. 14620 - 14625
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2013, Volume 288, Issue 41, pp. 29562 - 29572
Journal Article
Biomedical Optics Express, ISSN 2156-7085, 12/2018, Volume 9, Issue 12, pp. 6186 - 6204
With the emergence of immunotherapies for cancer treatment, there is a rising clinical need to visualize the tumor microenvironment (TME) non-invasively in... 
SYSTEM | SURGERY | BIOCHEMICAL RESEARCH METHODS | TUMOR | COHERENCE TOMOGRAPHY | DOUBLE-CLAD FIBER | PLATFORM | FLUORESCENCE | OPTICS | MONOCLONAL-ANTIBODIES | CATHETER | CARCINOMA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2006, Volume 103, Issue 35, pp. 13068 - 13073
Journal Article
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 07/2018, Volume 59, Issue 7, p. 1146
Linker instability and impaired tumor targeting can affect the tolerability and efficacy of antibody-drug conjugates (ADCs). To improve these ADC... 
Tissue Distribution | Isotopes - chemistry | Animals | Zirconium - chemistry | Immunoconjugates - pharmacokinetics | Isotope Labeling | Deferoxamine - chemistry | Mice | Immunoconjugates - chemistry | Platinum - chemistry
Journal Article
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 2013, Volume 13, Issue 4, pp. 446 - 457
Positron emission tomography with 89Zr can be used to follow the behaviour of therapeutic monoclonal antibodies (mAbs) and other biologicals in vivo. The... 
Proteins | Zirconium-89 | Monoclonal antibodies | Immuno-PET | Positron emission tomography | Radiometal | PET | Biologicals
Journal Article