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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 10, p. 2383
More than two decades ago, the activation mechanism for the membrane-bound photoreceptor and prototypical G protein-coupled receptor (GPCR) rhodopsin was... 
Spectroscopy | Rhodopsin | G protein-coupled receptors | Computer simulation | Molecular dynamics | Retina | Helices | Activation | Selectivity | Electron spin | Guanine | Proteins | Coupling (molecular) | Spin dynamics | Simulation | Dynamic stability | Pigments | Electron paramagnetic resonance | Binding sites
Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 533, pp. 265 - 268
Journal Article
Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7562, pp. 561 - 567
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 10, pp. 2383 - 2388
More than two decades ago, the activation mechanism for the membrane-bound photoreceptor and prototypical G protein-coupled receptor (GPCR) rhodopsin was... 
Pulsed dipolar spectroscopy | GPCR | Rhodopsin | G protein | Index Medicus | rhodopsin | Biological Sciences | pulsed dipolar spectroscopy
Journal Article
Journal Article
Nature, ISSN 0028-0836, 06/2018, Volume 558, Issue 7711, pp. 553 - 558
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 23, pp. 9420 - 9424
In G-protein signaling, an activated receptor catalyzes GDP/GTP exchange on the G α subunit of a heterotrimeric G protein. In an initial step, receptor... 
Proteins | Exchange rates | Receptors | Biochemical mechanisms | Software packages | Drug interactions | Biochemistry | Nucleotides | Color semiotics | Crystal structure | Signal transduction | Structural polymorphism | BETA-GAMMA | HETEROTRIMERIC G-PROTEIN | MECHANISM | signal transduction | structural polymorphism | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | HELIX | DISTANCE MEASUREMENTS | G(I-ALPHA-1) | PEPTIDE ANALOGS | GAMMA-SUBUNIT | BINDING | Receptors, G-Protein-Coupled - metabolism | GTP-Binding Protein alpha Subunits - chemistry | Molecular Sequence Data | Guanosine Triphosphate - metabolism | Spin Labels | Rhodopsin - metabolism | GTP-Binding Proteins - genetics | Cell Membrane - metabolism | Guanosine Triphosphate - chemistry | Guanosine Diphosphate - chemistry | Guanosine Diphosphate - metabolism | Rhodopsin - chemistry | Protein Structure, Tertiary | Amino Acid Sequence | Cross-Linking Reagents - chemistry | GTP-Binding Protein alpha Subunits - metabolism | GTP-Binding Proteins - chemistry | Protein Structure, Secondary | Models, Molecular | Rats | Electron Spin Resonance Spectroscopy - methods | Animals | Protein Binding | Mutation | Receptors, G-Protein-Coupled - chemistry | GTP-Binding Proteins - metabolism | Studies | Catalysis | Spectrum analysis | Binding sites | Index Medicus | Biological Sciences
Journal Article
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2019, Volume 9, Issue 1, pp. 11283 - 14
Journal Article
Biophysical Journal, ISSN 0006-3495, 02/2017, Volume 112, Issue 3, pp. 357a - 357a
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 09/2006, Volume 13, Issue 9, pp. 772 - 777
Heptahelical receptors activate intracellular signaling pathways by catalyzing GTP for GDP exchange on the heterotrimeric G protein alpha subunit (G alpha).... 
GTPASE ACTIVITY | CONTACT SITES | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | PROTEOLYTIC DIGESTION | COMPLEX-FORMATION | GUANINE-NUCLEOTIDE-BINDING | CONFORMATIONAL-CHANGES |