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ACS Nano, ISSN 1936-0851, 03/2015, Volume 9, Issue 3, pp. 2377 - 2389
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 11/2012, Volume 303, Issue 9, pp. 814 - 823
Cigarette smoke mediates DNA damage, lipid peroxidation, and modification and misfolding of proteins, thereby inducing severe cellular damage. The ubiquitin... 
Oxidative stress | Chronic obstructive pulmonary disease | Protein quality control | Ubiquitin proteasome system | Cigarette smoke | SYSTEM | PHYSIOLOGY | UBIQUITIN | ubiquitin proteasome system | ANTIGEN PRESENTATION | cigarette smoke | 20S PROTEASOME | CARDIOMYOPATHIES | OBSTRUCTIVE PULMONARY-DISEASE | RESPIRATORY SYSTEM | protein quality control | DEGRADATION | INHIBITORS | PROTEINS | oxidative stress | chronic obstructive pulmonary disease | Smoking - adverse effects | Protein Carbonylation | Oxidative Stress | Apoptosis - drug effects | Humans | Smoke | Polyubiquitin | Lung - enzymology | Protein Processing, Post-Translational - drug effects | Plant Preparations - pharmacology | Female | Ubiquitinated Proteins - metabolism | Gene Expression | Oxidation-Reduction | Proteasome Inhibitors - pharmacology | Cell Survival | Mice, Inbred C57BL | Alveolar Epithelial Cells - metabolism | Alveolar Epithelial Cells - drug effects | Proteasome Inhibitors - toxicity | Proteasome Endopeptidase Complex - physiology | Tobacco - toxicity | Proteasome Endopeptidase Complex - genetics | Plant Preparations - toxicity | Animals | Lung - drug effects | Cell Line, Tumor | Mice | Proteasome Endopeptidase Complex - metabolism | Alveolar Epithelial Cells - physiology | Glutathione - blood | Physiological aspects | Lungs | Ubiquitin-proteasome system | Health aspects
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2010, Volume 53, Issue 22, pp. 8192 - 8196
Journal Article
Journal Article
MedChemComm, ISSN 2040-2503, 07/2011, Volume 2, Issue 7, pp. 666 - 668
This first in vivo antitumour activity for an organometallic osmium arene complex, [Os(eta(6)-p-cym)(4-(2-pyridylazo)-N,N-dimethylaniline)I]PF6, is reported.... 
PROFILES | CHEMISTRY, MEDICINAL | RUTHENIUM(II) | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTITUMOR DRUGS | IN-VIVO
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 02/2011, Volume 22, Issue 2, p. 218
Attaching peptides to metallodrugs may result in improved biological properties of the complexes. The potential use of cell penetrating peptides (CPPs) as cell... 
Peptides | Toxicity | DNA damage | Effects | Chemical synthesis | DNA repair | Cells | Ovarian cancer
Journal Article
American Journal of Physiology, ISSN 1040-0605, 11/2012, Volume 303, Issue 9, p. L814
  Cigarette smoke mediates DNA damage, lipid peroxidation, and modification and misfolding of proteins, thereby inducing severe cellular damage. The ubiquitin... 
Lungs | DNA damage | Rodents | Lipids | Oxidation | Cells | Smoking
Journal Article
2010
Drawbacks associated with anticancer chemotherapeutic cisplatin include tumour drug resistance, non-effectiveness against all tumours and lack of... 
QD Chemistry : RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Dissertation
2009, Cancer Drug Discovery and Development, ISBN 9781603274586
Our studies of half-sandwich osmium(II) arene complexes of the type [(η6-arene)Os(XY)Z] show that hydrolysis of the Os–Z (Z = Cl) bond and degree of formation... 
Biomedicine | Cancer Research | Pharmacology/Toxicology
Book Chapter
Biomedical Microdevices, ISSN 1387-2176, 12/2017, Volume 19, Issue 4, pp. 1 - 10
Journal Article
Journal Article
Chemical Communications, ISSN 1359-7345, 12/2010, Volume 46, Issue 46, pp. 8794 - 8796
Journal Article
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