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Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 3234 - 3234
Journal Article
PLoS Genetics, ISSN 1553-7390, 04/2013, Volume 9, Issue 4
  Seminoma is a subclass of human testicular germ cell tumors (TGCT), the most frequently observed cancer in young men with a rising incidence. Here we... 
Proteins | Zebrafish | Genetics | Mutation | Tumors
Journal Article
Journal Article
Mechanisms of Development, ISSN 0925-4773, 08/2009, Volume 126, pp. S60 - S61
Journal Article
Molecular Cell, ISSN 1097-2765, 04/2016, Volume 62, Issue 1, pp. 34 - 46
Journal Article
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. 804 - 804
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 2008, Volume 19, Issue 6, pp. 1128 - 1138
Cilia perform essential motile and sensory functions central to many developmental and physiological processes. Disruption of their structure or function can... 
CHLAMYDOMONAS FLAGELLA | KUPFFERS VESICLE | EPITHELIAL-CELLS | LIGHT-CHAIN | HUMAN LATERALITY DISORDERS | MOTOR DOMAIN | UROLOGY & NEPHROLOGY | LEUCINE-RICH REPEAT | LEFT-RIGHT ASYMMETRY | INTRAFLAGELLAR TRANSPORT | PRIMARY CILIUM | Proteins - genetics | Animals | Polycystic Kidney Diseases - etiology | Humans | Zebrafish | Mice | Mutation | Cilia | Index Medicus | Basic Research
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 1987 - 1997
Patients with a germline mutation in von Hippel-Lindau (VHL) develop renal cell cancers and hypervascular tumors of the brain, adrenal glands, and pancreas as... 
INACTIVATION | MEDICINE, RESEARCH & EXPERIMENTAL | HIF-2-ALPHA | ERYTHROPOIESIS | SUNITINIB | IRON | CAUSES POLYCYTHEMIA | HYPOXIA-INDUCIBLE FACTOR-2 | EXPRESSION | CANCER | RENAL-CELL CARCINOMA | Polycythemia - genetics | Sulfones - therapeutic use | Liver - pathology | Kidney - pathology | Humans | Myocardial Contraction - drug effects | Amino Acids, Dicarboxylic - toxicity | Sulfones - pharmacology | Zebrafish - embryology | Hypoxia-Inducible Factor 1, alpha Subunit - deficiency | Retinal Vessels - pathology | Brain - blood supply | von Hippel-Lindau Disease - pathology | Tumor Suppressor Proteins - deficiency | Hydrazones - therapeutic use | Tumor Suppressor Proteins - genetics | von Hippel-Lindau Disease - drug therapy | Drug Evaluation, Preclinical | Basic Helix-Loop-Helix Transcription Factors - deficiency | Disease Models, Animal | Basic Helix-Loop-Helix Transcription Factors - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Basic Helix-Loop-Helix Transcription Factors - antagonists & inhibitors | von Hippel-Lindau Disease - genetics | von Hippel-Lindau Disease - physiopathology | Zebrafish - genetics | Hydrazones - pharmacology | Gene Expression Regulation - drug effects | Phenotype | Zebrafish Proteins - deficiency | Animals | 5' Untranslated Regions | Neovascularization, Pathologic - drug therapy | Embryo, Nonmammalian | Neovascularization, Pathologic - genetics | Zebrafish Proteins - genetics | Polycythemia - drug therapy | Index Medicus | Abridged Index Medicus | Angiogenesis | Oncology
Journal Article
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 113, Issue 25, pp. 6449 - 6460
Journal Article
The Journal of experimental medicine, ISSN 0022-1007, 03/2017, Volume 214, Issue 3, pp. 623 - 637
Journal Article
Blood, ISSN 0006-4971, 06/2009, Volume 113, Issue 25, pp. 6449 - 6460
We have generated 2 zebrafish lines carrying inactivating germline mutations in the von Hippel-Lindau (VHL) tumor suppressor gene ortholog vhl. Mutant embryos... 
Journal Article