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Clinical Cancer Research, ISSN 1078-0432, 02/2007, Volume 13, Issue 4, pp. 1076 - 1082
Nuclear factor-κB (NF-κB) is a signal transcription factor that has emerged as an important modulator of altered gene programs and malignant phenotype in... 
proteasome | NF-kappaB | cancer | Inhibitor-kappaB Kinase | NSAID
Journal Article
Oral diseases, ISSN 1354-523X, 10/2017, Volume 23, Issue 7, pp. 820 - 821
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 1448 - 1448
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2015, Volume 1280, pp. 459 - 468
Immunohistochemistry is a valuable molecular technique based upon the principle of antibody specificity for target antigens in tissues with subsequent... 
Immunohistochemistry | NF-κB | Frozen tissue | Isotype control | Tissue fi xation | Histoscore | Peroxidase | Immunohistochemistry - methods | Neoplasms - metabolism | NF-kappa B - metabolism | Neoplasms - pathology | Humans | Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 03/2015, Volume 21, Issue 5, pp. 942 - 943
Journal Article
Cancer Discovery, ISSN 2159-8274, 08/2011, Volume 1, Issue 3, pp. 200 - 202
Xue et al. demonstrate response and increased survival but development of acquired resistance to proteasome and inhibitor-kappa B kinase inhibitors targeting... 
HEAD | ACTIVATOR | BORTEZOMIB | ONCOLOGY | NECK-CANCER | Lung Neoplasms - drug therapy | NF-kappa B - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Animals | Adenocarcinoma of Lung | Adenocarcinoma - drug therapy | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2016, Volume 113, Issue 7, pp. 1883 - 1888
Journal Article
Oncogene, ISSN 0950-9232, 07/2012, Volume 31, Issue 28, pp. 3322 - 3332
The molecular mechanisms that contribute to the initiation and progression of head and neck squamous cell carcinoma (HNSCC) have not been completely... 
cancer mouse model | TGF-β | conditional knockout | head and neck squamous cell carcinoma | PI3K/Akt | PATHWAYS | APOPTOSIS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MAMMARY-CARCINOMA | FACTOR-KAPPA-B | MODEL | CELL BIOLOGY | COLON-CANCER | TGF-beta | GROWTH-FACTOR-BETA | ONCOLOGY | GENETICS & HEREDITY | TUMOR-SUPPRESSOR | TUMORIGENESIS | Cell Proliferation | Epithelial Cells - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Cell Count | Humans | Transforming Growth Factor beta1 - metabolism | Apoptosis - genetics | Phosphatidylinositol 3-Kinases - metabolism | Inflammation - complications | Neoplastic Stem Cells - metabolism | Neoplastic Stem Cells - pathology | Proto-Oncogene Proteins c-akt - metabolism | Cellular Senescence - genetics | PTEN Phosphohydrolase - genetics | PTEN Phosphohydrolase - deficiency | PTEN Phosphohydrolase - metabolism | Epithelial Cells - pathology | Penetrance | Signal Transduction - genetics | Transforming Growth Factor beta1 - genetics | Gene Knockout Techniques | Head and Neck Neoplasms - pathology | Animals | Carcinoma, Squamous Cell - complications | Cell Line, Tumor | Head and Neck Neoplasms - complications | Head and Neck Neoplasms - genetics | Mice | Myeloid Cells - pathology | Index Medicus | Cell proliferation | Animal models | Senescence | Transformation | biomarkers | AKT protein | Inflammation | Transforming growth factor- beta | Suppressor cells | Carcinogenesis | 1-Phosphatidylinositol 3-kinase | Metastases | Angiogenesis | Signal transduction | Cell activation | Molecular modelling | Stem cells | Head and neck | Head and neck cancer | Microenvironments | PTEN protein | Apoptosis | Tumors | squamous cell carcinoma | Head and Neck Squamous Cell Carcinoma (HNSCC) | Akt | PI3K | Conditional Knockout | Cancer Mouse Model
Journal Article
Cancer, ISSN 0008-543X, 05/2017, Volume 123, Issue 10, pp. 1695 - 1698
Recent genomic studies of head and neck squamous cell carcinoma by The Cancer Genome Atlas as well as other groups identified deletions or mutations in tumor... 
NF-kappa B | Deubiquitinating Enzyme CYLD | Interferons | Humans | Papillomaviridae | Head and Neck Neoplasms | TNF Receptor-Associated Factor 3 | Index Medicus | Abridged Index Medicus
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 05/2017, Volume 77, Issue 10, pp. 2607 - 2619
Checkpoint inhibitors are relatively inefficacious in head and neck cancers, despite an abundance of genetic alterations and a T-cell-inflamed phenotype. One... 
HEAD | RESPONSES | ONCOLOGY | IMMUNE SUPPRESSION | REGULATORY T-CELLS | PI3K-GAMMA | BLOCKADE | EXPRESSION | CARCINOMA | NECK-CANCER | TUMOR MICROENVIRONMENT | Neoplasms - metabolism | Immunomodulation - drug effects | Myeloid-Derived Suppressor Cells - drug effects | Lymphocyte Activation - immunology | Isoquinolines - pharmacology | Lymphocytes, Tumor-Infiltrating - metabolism | Antineoplastic Agents - pharmacology | Epitopes, T-Lymphocyte - immunology | Myeloid-Derived Suppressor Cells - metabolism | Disease Models, Animal | Myeloid-Derived Suppressor Cells - immunology | Purines - pharmacology | Antibodies, Monoclonal - pharmacology | Lymphocytes, Tumor-Infiltrating - drug effects | Class I Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Neoplasms - drug therapy | Tumor Microenvironment - immunology | Animals | B7-H1 Antigen - antagonists & inhibitors | Lymphocyte Activation - drug effects | Neoplasms - immunology | Survival Analysis | Cell Line, Tumor | Mice | Protein Kinase Inhibitors - pharmacology | Neoplasms - pathology | Lymphocytes, Tumor-Infiltrating - immunology | Cell culture | Myeloid cells | Effectiveness | Cell survival | CD8 antigen | Effector cells | Lymphocytes T | Inflammation | Suppressor cells | Recruitment | Immune systems | Immunosuppression | Inhibitors | Immune checkpoint | Lymphocytes | PD-L1 protein | Isoforms | Head and neck | Neck | Head & neck cancer | Inhibition | Cancer | Index Medicus | immunosuppression | MDSC | IPI-145 | PI3K | head and neck cancer
Journal Article
Oral Oncology, ISSN 1368-8375, 10/2014, Volume 50, Issue 10, p. 930
Nuclear factor-kappa B (NF-[kappa]B) transcription factors regulate cellular processes such as inflammation and cell survival. The NF-[kappa]B pathway is often... 
Prevention | Squamous cell carcinoma | Hypoglycemic agents | Cancer
Journal Article
Cancer, ISSN 0008-543X, 5/2017, Volume 123, Issue 10, pp. 1695 - 1698
Intriguingly, recent genomic studies of HNSCC by The Cancer Genome Atlas (TCGA) as well as other groups identified deletions or mutations in TNF-receptor... 
CYLD | Squamous Cell Carcinoma | Nuclear Factor-kappaB | Human Papilloma Virus | TRAF3
Journal Article
Case reports in otolaryngology, ISSN 2090-6765, 2016, Volume 2016, pp. 2313714 - 5
Journal Article
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