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Clinical Infectious Diseases, ISSN 1058-4838, 07/2019, Volume 69, Issue 3, pp. 559 - 560
Journal Article
Annual review of pharmacology and toxicology, ISSN 0362-1642, 1/2020, Volume 60, Issue 1, pp. 311 - 331
Pharmacogenetics is a key component of precision medicine. Genetic variation in drug metabolism enzymes can lead to variable exposure to drugs and metabolites,... 
pharmacogenomics | psychiatry | infectious disease | immunology | oncology | pediatrics
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 07/2019, Volume 106, Issue 1, pp. 84 - 86
Journal Article
Circulation Research, ISSN 0009-7330, 04/2018, Volume 122, Issue 9, pp. 1176 - 1190
This review will provide an overview of the principles of pharmacogenomics from basic discovery to implementation, encompassing application of tools of... 
Clopidogrel | Warfarin | Drug development | Genomics
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 04/2014, Volume 95, Issue 4, pp. 423 - 431
Journal Article
by Jarvik, Gail P and Amendola, Laura M and Berg, Jonathan S and Brothers, Kyle and Clayton, Ellen W and Chung, Wendy and Evans, Barbara J and Evans, James P and Fullerton, Stephanie M and Gallego, Carlos J and Garrison, Nanibaa’ A and Gray, Stacy W and Holm, Ingrid A and Kullo, Iftikhar J and Lehmann, Lisa Soleymani and McCarty, Cathy and Prows, Cynthia A and Rehm, Heidi L and Sharp, Richard R and Salama, Joseph and Sanderson, Saskia and Van Driest, Sara L and Williams, Marc S and Williams, Janet and Wolf, Wendy A and Wolf, Susan M and Harley, John and Myers, Melanie and Namjou, Bahram and Vinks, Sander and Connolly, John and Keating, Brendan and Gerhard, Glenn and Sundaresan, Agnes and Tromp, Gerard and Crosslin, David and Leppig, Kathy and Wicklund, Cathy and Chute, Christopher and Lynch, John and De Andrade, Mariza and Heit, John and McCormick, Jen and Brilliant, Murray and Kitchner, Terrie and Ritchie, Marylyn and Böttinger, Erwin and Peter, Inga and Persell, Stephen and Rasmussen-Torvik, Laura and McGregor, Tracy and Roden, Dan and Antommaria, Armand and Chiavacci, Rosetta and Faucett, Andy and Ledbetter, David and Hartzler, Andrea and Vitek, Carolyn R. Rohrer and Frost, Norm and Ferryman, Kadija and Horowitz, Carol and Rhodes, Rosamond and Zinberg, Randi and Aufox, Sharon and Pan, Vivian and Long, Rochelle and Ramos, Erin and Odgis, Jackie and Wise, Anastasia and Hull, Sara and Gitlin, Jonathan and Green, Robert and Metterville, Danielle and McGuire, Amy and Kong, Sek Won and Trinidad, Sue and Veenstra, David and Roche, Myra and Skinner, Debra and Raspberry, Kelly and O’Daniel, Julianne and Parsons, Will and Eng, Christine and Hilsenbeck, Susan and Karavite, Dean and Conlin, Laura and Spinner, Nancy and Krantz, Ian and Falk, Marni and Santani, Avni and Dechene, Elizabeth and Dulik, Matthew and Bernhardt, Barbara and Schuetze, Scott and Everett, Jessica and Gornick, Michele Caroline and Wilfond, Ben and Tabor, Holly and Lemke, Amy A and Richards, Sue and ... and CERC Comm and CSER Act-ROR Working Grp and eMERGE Act-ROR Comm and eMERGE Act-ROR Committee and CERC Committee and CSER Act-ROR Working Group
The American Journal of Human Genetics, ISSN 0002-9297, 06/2014, Volume 94, Issue 6, pp. 818 - 826
Journal Article
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 12/2018
Journal Article
JAMA Pediatrics, ISSN 2168-6203, 07/2018, Volume 172, Issue 7, p. 655
Importance Acute kidney injury (AKI) is a common and serious complication for pediatric cardiac surgery patients associated with increased morbidity,... 
Heart | Heart surgery | Erythrocytes | Risk | Red blood cells | Analgesics | Surgery | Hemoglobin | Oxidation | Children | Age | Creatinine | Postoperative period | Kidneys | Risk reduction | Pharmacology | Exposure | Regression analysis | Chemical compounds | Patients | Morbidity | Hypotension | Injury prevention | Valence | Acetaminophen | Kidney diseases | Oxygenation
Journal Article
Clinical pharmacology and therapeutics, ISSN 0009-9236, 5/2018, Volume 103, Issue 5, pp. 787 - 794
The development of new knowledge around the genetic determinants of variable drug action has naturally raised the question of how this new knowledge can be... 
Journal Article
Pediatric research, ISSN 0031-3998, 08/2019
Pediatric acute kidney injury (AKI) is common and associated with increased morbidity, mortality, and length of stay. We performed a pragmatic randomized trial... 
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 10/2018, Volume 67, Issue 9, pp. 1356 - 1363
Daptomycin-associated myopathy is a known adverse effect, so creatine phosphokinase (CPK) monitoring is advised. Statin coadministration with daptomycin was... 
daptomycin | rhabdomyolysis | statin | myopathy | drug-drug interaction | INFECTIOUS DISEASES | MULTICENTER | COA REDUCTASE INHIBITORS | SAFETY | MICROBIOLOGY | PATIENTS RECEIVING DAPTOMYCIN | SINGLE-DOSE PHARMACOKINETICS | IMMUNOLOGY | RENAL IMPAIRMENT | COMPLICATED SKIN | SKIN-STRUCTURE INFECTIONS | STAPHYLOCOCCUS-AUREUS | CLINICAL-OUTCOMES | and Commentaries
Journal Article
JAMA, ISSN 0098-7484, 01/2016, Volume 315, Issue 1, pp. 47 - 57
Journal Article
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 03/2018, Volume 103, Issue 3, pp. 409 - 418
Drug development continues to be costly and slow, with medications failing due to lack of efficacy or presence of toxicity. The promise of pharmacogenomic... 
RECORDS | BIOBANK | VARIANTS | GENOTYPE | PHENOME-WIDE ASSOCIATION | IMPLEMENTATION | RISK | CLASSIFICATION | PHARMACOLOGY & PHARMACY | HEALTH | CANCER | Phenotype | Research | Genetic variation | Genomics | Analysis | Index Medicus | Abridged Index Medicus
Journal Article
PEDIATRICS, ISSN 0031-4005, 12/2019, Volume 144, Issue 6, p. e20190857
OBJECTIVES: Proton pump inhibitors (PPIs) are often used in pediatrics to treat common gastrointestinal disorders, and there are growing concerns for... 
OPT-OUT | PANTOPRAZOLE | LANSOPRAZOLE | METABOLISM | GENOTYPE | OMEPRAZOLE | PEDIATRICS | SINGLE-DOSE PHARMACOKINETICS | PHARMACOGENETICS | POLYMORPHISM | CHILDREN
Journal Article