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by Thorsson, Vesteinn and Thorsson, Vésteinn and Gibbs, Richard A and Gibbs, David L and Brown, Scott D and Wolf, Gregory and Wolf, Denise and Bortone, Dante S and Ou Yang, Tai-Hsien and Porta-Pardo, Eduard and Gao, Galen F and Gao, Jianjiong and Plaisier, Christopher L and Eddy, James A and Ziv, Elad and Culhane, Aedin C and Paull, Evan O and Sivakumar, I.K. Ashok and Gentles, Andrew J and Malhotra, Raunaq and Farshidfar, Farshad and Colaprico, Antonio and Parker, Joel S and Mose, Lisle E and Vo, Nam Sy and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Rader, Janet and Dhankani, Varsha and Reynolds, Sheila and Reynolds, Sheila M and Bowlby, Reanne and Califano, Andrea and Cherniack, Andrew D and Anastassiou, Dimitris and Bedognetti, Davide and Mokrab, Younes and Newman, Aaron M and Rao, Arvind and Chen, Amy and Chen, Chu and Chen, Ken and Krasnitz, Alexander and Hu, Jianhong and Hu, Hai and Malta, Tathiane M and Noushmehr, Houtan and Pedamallu, Chandra Sekhar and Bullman, Susan and Ojesina, Akinyemi I and Lamb, Andrew and Zhou, Wanding and Shen, Hui and Choueiri, Toni K and Weinstein, John N and Guinney, Justin and Saltz, Joel and Holt, Robert and Holt, Robert A and Rabkin, Charles S and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jioajiao and Wang, Min and Wang, Linghua and Wang, Zhining and Wang, Timothy and Wang, Jing and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Yang, Ian and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Jiexin and Zhang, Lizhi and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 812 - 830.e14
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across... 
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory | GENOMIC ANALYSES | INFORMATION | T-CELL-RECEPTOR | REGULATORY NETWORK | CLASSIFICATION | IMMUNOLOGY | SEQUENCING DATA | SOMATIC MUTATIONS | COMPREHENSIVE ANALYSIS | PREDICTION | REVEALS | Transforming Growth Factor beta - immunology | Prognosis | Humans | Middle Aged | Th1-Th2 Balance - physiology | Male | Neoplasms - classification | Wound Healing - immunology | Young Adult | Transforming Growth Factor beta - genetics | Neoplasms - genetics | Neoplasms - immunology | Interferon-gamma - immunology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Interferon-gamma - genetics | Wound Healing - genetics | Genomics - methods | Child | Macrophages - immunology | Cell proliferation | Cluster analysis | Transcription | Copy number | p53 Protein | Lung cancer | Genomics | Aneuploidy | Lymphocytes T | Genomes | Cell interactions | Macrophages | Immunotherapy | DNA methylation | Deoxyribonucleic acid--DNA | Immune system | Medical research | Wound healing | Immunomodulation | MiRNA | Stockholders | Inflammation | T cell receptors | Communications networks | Gene expression | White blood cells | Inventors | Medical prognosis | γ-Interferon | Mutation | Cancer | Tumors | Immune Subtypes | Integrative Network Analysis | Cancer Genomics | Immuno-oncology | Tumor immunology
Journal Article
by Chin, L and Meyerson, M and Aldape, K and Bigner, D and Mikkelsen, T and VandenBerg, S and Kahn, A and Penny, R and Gerhard, D. S and Getz, G and Brennan, C and Taylor, B. S and Winckler, W and Park, P and Ladanyi, M and Hoadley, K. A and Verhaak, R. G. W and Hayes, D. N and Spellman, Paul T and Absher, D and Weir, B. A and Ding, L and Wheeler, D and Lawrence, M. S and Cibulskis, K and Mardis, E and Zhang, Jinghui and Wilson, R. K and Donehower, L and Wheeler, D. A and Purdom, E and Wallis, J and Laird, P. W and Herman, J. G and Schuebel, K. E and Weisenberger, D. J and Baylin, S. B and Schultz, N and Yao, Jun and Wiedemeyer, R and Weinstein, J and Sander, C and Gibbs, R. A and Gray, J and Kucherlapati, R and Lander, E. S and Myers, R. M and Perou, C. M and McLendon, Roger and Friedman, Allan and Van Meir, Erwin G and Brat, Daniel J and Mastrogianakis, Gena Marie and Olson, Jeffrey J and Lehman, Norman and Yung, W. K. Alfred and Bogler, Oliver and Berger, Mitchel and Prados, Michael and Muzny, Donna and Morgan, Margaret and Scherer, Steve and Sabo, Aniko and Nazareth, Lynn and Lewis, Lora and Hall, Otis and Zhu, Yiming and Ren, Yanru and Alvi, Omar and Yao, Jiqiang and Hawes, Alicia and Jhangiani, Shalini and Fowler, Gerald and San Lucas, Anthony and Kovar, Christie and Cree, Anew and Dinh, Huyen and Santibanez, Jireh and Joshi, Vandita and Gonzalez-Garay, Manuel L and Miller, Christopher A and Milosavljevic, Aleksandar and Sougnez, Carrie and Fennell, Tim and Mahan, Scott and Wilkinson, Jane and Ziaugra, Liuda and Onofrio, Robert and Bloom, Toby and Nicol, Rob and Ardlie, Kristin and Baldwin, Jennifer and Gabriel, Stacey and Fulton, Robert S and McLellan, Michael D and Larson, David E and Shi, Xiaoqi and Abbott, Rachel and Fulton, Lucinda and Chen, Ken and ... and Tissue Source Sites and Canc Genome Atlas Res Network and Canc Genome Characterization Ctr and Genome Sequencing Ctr and Project Teams and Cancer Genome Atlas Research Network and The Cancer Genome Atlas Research Network
Nature, ISSN 0028-0836, 10/2008, Volume 455, Issue 7216, pp. 1061 - 1068
Journal Article
by Brennan, Cameron W and Verhaak, Roel G.W and McKenna, Aaron and Campos, Benito and Noushmehr, Houtan and Salama, Sofie R and Zheng, Siyuan and Chakravarty, Debyani and Sanborn, J. Zachary and Berman, Samuel H and Beroukhim, Rameen and Bernard, Brady and Wu, Junyuan and Wu, Chang-Jiun and Genovese, Giannicola and Shmulevich, Ilya and Barnholtz-Sloan, Jill and Zou, Lihua and Vegesna, Rahulsimham and Shukla, Sachet A and Ciriello, Giovanni and Yung, W.K and Yung, W.K. Alfred and Zhang, Zhaobin and Zhang, Wei and Zhang, Jianhua and Zhang, Hailei and Sougnez, Carrie and Mikkelsen, Tom and Aldape, Kenneth and Bigner, Darell D and Bigner, Darell and Van Meir, Erwin G and Prados, Michael and Sloan, Andrew and Sloan, Andrew E and Black, Keith L and Eschbacher, Jennifer and Finocchiaro, Gaetano and Friedman, William and Andrews, David W and Guha, Abhijit and Iacocca, Mary and O’Neill, Brian P and Foltz, Greg and Myers, Jerome and Weisenberger, Daniel J and Penny, Robert and Kucherlapati, Raju and Perou, Charles M and Hayes, D. Neil and Gibbs, Richard and Marra, Marco and Mills, Gordon and Mills, Gordon B and Lander, Eric S and Lander, Eric and Spellman, Paul and Wilson, Richard K and Wilson, Richard and Sander, Chris and Weinstein, John N and Weinstein, John and Meyerson, Matthew and Gabriel, Stacey B and Gabriel, Stacey and Laird, Peter W and Haussler, David and Getz, Gad and Chin, Lynda and Benz, Christopher and Barrett, Wendi and Ostrom, Quinn and Wolinsky, Yingli and Bose, Bikash and Boulos, Madgy and Boulos, Paul T and Brown, Jenn and Czerinski, Christine and Eppley, Matthew and Kempista, Thelma and Kitko, Teresa and Koyfman, Yakov and Rabeno, Brenda and Rastogi, Pawan and Sugarman, Michael and Swanson, Patricia and Yalamanchii, Kennedy and Otey, Ilana P and Liu, Yuexin and Liu, Yingchun Spring and Liu, Wenbin and Xiao, Yonghong and Auman, J.Todd and Chen, Qing-Rong and Chen, Peng-Chieh and Chen, Ken and Hadjipanayis, Angela and Lee, Eunjung and Lee, Semin and ... and TCGA Res Network
Cell, ISSN 0092-8674, 10/2013, Volume 155, Issue 2, pp. 462 - 477
We describe the landscape of somatic genomic alterations based on multidimensional and comprehensive characterization of more than 500 glioblastoma tumors... 
PATHWAYS | SURVIVAL | GRADE GLIOMA | MELANOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMAN CANCERS | COPY-NUMBER ALTERATION | TUMORS | EXPRESSION | DRIVER MUTATIONS | EGFR | CELL BIOLOGY | Platelet-derived growth factor | RNA | Gene mutations | Analysis | Methylation | Glioblastoma multiforme | Telomerase
Journal Article
by Ricketts, Christopher J and De Cubas, Aguirre A and Fan, Cheng and Fan, Huihui and Smith, Christof C and Smith, Jennifer and Lang, James and Lang, Martin and Reznik, Ed and Bowlby, Reanne and Gibb, Ewan A and Akbani, Rehan and Beroukhim, Rameen and Bottaro, Donald P and Choueiri, Toni K and Gibbs, Richard A and Godwin, Andrew K and Godwin, Eryn M and Haake, Scott and Hakimi, A. Ari and Henske, Elizabeth P and Hsieh, James J and Ho, Thai and Ho, Thai H and Kanchi, Rupa S and Krishnan, Bhavani and Kwiatkowski, David J and Lui, Wembin and Merino, Maria J and Mills, Gordon B and Myers, Jerome and Nickerson, Michael L and Reuter, Victor E and Reuter, Victor and Schmidt, Laura S and Schmidt, Heather K and Shelley, C. Simon and Shelley, Carl Simon and Shen, Hui and Shuch, Brian and Signoretti, Sabina and Srinivasan, Ramaprasad and Tamboli, Pheroze and Thomas, George and Vincent, Benjamin G and Vocke, Cathy D and Wheeler, David A and Yang, Lixing and Yang, Ian and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Kim, Jaegil and Kim, William Y and Robertson, A. Gordon and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Timothy and Wang, Linghua and Wang, Jioajiao and Wang, Min and Wang, Zhining and Wang, Jing and Zenklusen, Jean C and Zhang, Hailei and Zhang, Jiashan (Julia) and Zhang, Wei and Zhang, Hongxin and Zhang, Lizhi and Zhang, Jiexin and Zhang, Hongzheng and Chudamani, Sudha and Liu, Wenbin and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 1, pp. 313 - 326.e5
Journal Article