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Molecular Cancer, ISSN 1476-4598, 09/2010, Volume 9, Issue 1, pp. 240 - 240
Journal Article
Cancer Research, ISSN 0008-5472, 09/2015, Volume 75, Issue 18, pp. 3865 - 3878
Journal Article
Molecular Cancer, ISSN 1476-4598, 03/2011, Volume 10, Issue 1, pp. 32 - 32
Background: Truncated dopamine and cyclic-AMP-regulated phosphoprotein (t-DARPP) is frequently overexpressed in gastrointestinal malignancies. In this study,... 
WNT SIGNALING PATHWAY | ONCOLOGY | GASTRIC-CANCER | CYCLIN D1 | WINGLESS SIGNAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLYCOGEN-SYNTHASE KINASE-3 | TRANSCRIPTION FACTOR LEF-1 | ESOPHAGOGASTRIC JUNCTION | BARRETTS-ESOPHAGUS | MULTIDRUG-RESISTANCE | COLON-CARCINOMA | Phosphorylation | Cell Proliferation | Gastrointestinal Neoplasms - genetics | Luciferases - metabolism | Humans | Dopamine and cAMP-Regulated Phosphoprotein 32 - genetics | Gene Expression Regulation, Neoplastic | Glycogen Synthase Kinase 3 beta | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Luciferases - genetics | TCF Transcription Factors - metabolism | Gastrointestinal Neoplasms - pathology | Cell Nucleus - metabolism | Protein Isoforms - metabolism | RNA Interference | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Gastrointestinal Neoplasms - metabolism | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Binding Sites - genetics | Glycogen Synthase Kinase 3 - metabolism | Dopamine and cAMP-Regulated Phosphoprotein 32 - metabolism | beta Catenin - metabolism | Blotting, Western | beta Catenin - genetics | Signal Transduction - drug effects | Upper Gastrointestinal Tract - pathology | Cell Line, Tumor | Mutation | TCF Transcription Factors - genetics | Upper Gastrointestinal Tract - metabolism | Microscopy, Fluorescence | Protein Isoforms - genetics | Index Medicus
Journal Article
Molecular Cancer, ISSN 1476-4598, 03/2011, Volume 10, p. 32
Truncated dopamine and cyclic-AMP-regulated phosphoprotein (t-DARPP) is frequently overexpressed in gastrointestinal malignancies. In this study, we examined... 
Gastrointestinal cancer | Cancer cells | Physiological aspects | Development and progression | Cadherins | Genetic aspects | Research | Proteins | Design | Medical research | Regulation | Kinases | Experiments | Manuscripts | Binding sites | Cancer
Journal Article
Biochemistry, ISSN 0006-2960, 9/2013, Volume 52, Issue 37, pp. 6515 - 6524
Replication Protein A (RPA) is the primary single stranded DNA (ssDNA) binding protein in eukaryotes. The N-terminal domain of the RPA70 subunit (RPA70N)... 
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 3340 - 3340
Journal Article
Gastroenterology, ISSN 0016-5085, 2010, Volume 138, Issue 5, pp. S-732 - S-733
Journal Article
Journal Article
CHEMMEDCHEM, ISSN 1860-7179, 04/2016, Volume 11, Issue 8, pp. 893 - 899
Replication proteinA (RPA) is an essential single-stranded DNA (ssDNA)-binding protein that initiates the DNA damage response pathway through protein-protein... 
CHEMISTRY, MEDICINAL | hit optimization | ASSAY | high-throughput screening | 70N DOMAIN | MODEL | DISCOVERY | protein-protein interactions | P53 TRANSACTIVATION DOMAIN | replication proteinA | PHARMACOLOGY & PHARMACY | BINDING | medicinal chemistry | ATR | Proteins | Optimization
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 02/2015, Volume 6, Issue 2, pp. 140 - 145
Replication Protein A is the primary eukaryotic ssDNA binding protein that has a central role in initiating the cellular response to DNA damage. RPA recruits... 
fragment-based discovery | Replication protein A | medicinal chemistry | BINDS | CHEMISTRY, MEDICINAL | FRAGMENT-LINKING | DNA | 70N DOMAIN | DISCOVERY | ATR | INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY | 60 APPLIED LIFE SCIENCES
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 07/2013, Volume 4, Issue 7, pp. 601 - 605
Replication protein A (RPA) is a ssDNA binding protein that is essential for DNA replication and repair. The initiation of the DNA damage response by RPA is... 
DNA damage | fragment-based discovery | Replication protein A | P53 TRANSACTIVATION DOMAIN | REPAIR | RPA | CHEMISTRY, MEDICINAL | DNA | BINDING
Journal Article
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