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by Godoy, Patricio and Hewitt, Nicola J and Albrecht, Ute and Andersen, Melvin E and Ansari, Nariman and Bhattacharya, Sudin and Bode, Johannes Georg and Bolleyn, Jennifer and Borner, Christoph and Boettger, Jan and Braeuning, Albert and Budinsky, Robert A and Burkhardt, Britta and Cameron, Neil R and Camussi, Giovanni and Cho, Chong-Su and Choi, Yun-Jaie and Rowlands, J. Craig and Dahmen, Uta and Damm, Georg and Dirsch, Olaf and Teresa Donato, Maria and Dong, Jian and Dooley, Steven and sdo, Dirk and Eakins, Rowena and Ferreira, Karine Sa and Fonsato, Valentina and Fraczek, Joanna and Gebhardt, Rolf and Gibson, Anew and Glanemann, Matthias and Goling, Chris E. P and Jose Gomez-Lechon, Maria and Groothuis, Geny M. M and Gustavsson, Lena and Guyot, Christelle and Hallifax, David and Hammad, Seddik and Hayward, Adam and Haeussinger, Dieter and Hellerbrand, Claus and Hewitt, Philip and Hoehme, Stefan and Holzhuetter, Hermann-Georg and Houston, J. Brian and Hrach, Jens and Ito, Kiyomi and Jaeschke, Hartmut and Keitel, Verena and Kelm, Jens M and Park, B. Kevin and Kordes, Claus and Kullak-Ublick, Gerd A and LeCluyse, Edward L and Lu, Peng and Luebke-Wheeler, Jennifer and Lutz, Anna and Maltman, Daniel J and Matz-Soja, Madlen and McMullen, Patrick and Merfort, Irmgard and Messner, Simon and Meyer, Christoph and Mwinyi, Jessica and Naisbitt, Dean J and Nussler, Aneas K and Olinga, Peter and Pampaloni, Francesco and Pi, Jingbo and Pluta, Linda and Przyborski, Stefan A and Ramachanan, Anup and Rogiers, Vera and Rowe, Cliff and Schelcher, Celine and Schmich, Kathrin and Schwarz, Michael and Singh, Bijay and Stelzer, Ernst H. K and Stieger, Bruno and Stoeber, Regina and Sugiyama, Yuichi and Tetta, Ciro and Thasler, Wolfgang E and Vanhaecke, Tamara and Vinken, Mathieu and Weiss, Thomas S and Widera, Agata and Woods, Courtney G and Xu, Jinghai James and Yarborough, Kathy M and Hengstler, Jan G and Lund University and Lunds universitet and Institutionen för translationell medicin and Department of Translational Medicine
Archives of toxicology, ISSN 0340-5761, 08/2013, Volume 87, Issue 8, pp. 1315 - 1530
This review encompasses the most important advances in liver functions and hepatotoxicity and analyzes which mechanisms can be studied in vitro. In a complex... 
Mechanisms of gene regulation | 3D Models | DILI | Biomedicine | Environmental Health | Occupational Medicine/Industrial Medicine | Cryopreservation | Mathematical modeling | Clearance | Pharmacology/Toxicology | Biomedicine general | Non-parenchymal cells | DILI3D Models | SALT EXPORT PUMP | PLURIPOTENT STEM-CELLS | HEPATIC STELLATE CELLS | ARYL-HYDROCARBON RECEPTOR | ANION-TRANSPORTING POLYPEPTIDE | CONSTITUTIVE ANDROSTANE RECEPTOR | FARNESOID-X-RECEPTOR | TOXICOLOGY | NF-KAPPA-B | DRUG-DRUG INTERACTIONS | PRIMARY RAT HEPATOCYTES | Inactivation, Metabolic | Culture Techniques - methods | Signal Transduction | Coculture Techniques | Humans | Gene Expression Regulation | Receptors, Cytoplasmic and Nuclear - genetics | Hepatocytes - metabolism | Hepatocytes - cytology | Animals | High-Throughput Screening Assays | Liver - drug effects | Toxicogenetics | Liver - physiology | Toxicity Tests - methods | Liver - cytology | Hepatocytes - drug effects | Organ Culture Techniques | Receptors, Cytoplasmic and Nuclear - metabolism | Cells | Liver cancer | Signal transduction | Cellular biology | Gene expression | Toxicity | Life Sciences | Modeling and Simulation | Toxicology | Pharmacology | Pharmaceutical sciences | Computer Science | Review | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Farmakologi och toxikologi | Pharmacology and Toxicology
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