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Journal Article
Cancer Cell, ISSN 1535-6108, 07/2018, Volume 34, Issue 1, pp. 148 - 162.e7
Targeting HER2 is effective in 24% of amplified metastatic colorectal cancer; however, secondary resistance occurs in most of the cases. We studied the... 
trastuzumab | targeted therapy | rapid autopsy | colorectal cancer | clonal evolution | HER2 amplification | lapatinib | liquid biopsy | ctDNA | resistance | BREAST-CANCER | HETEROGENEITY | PIK3CA MUTATIONS | THERAPY | AMPLIFICATION | SOLID TUMORS | GENE | ONCOLOGY | ACQUIRED-RESISTANCE | EGFR BLOCKADE | PATHOLOGICAL COMPLETE RESPONSE | CELL BIOLOGY | Predictive Value of Tests | ras Proteins - genetics | Liquid Biopsy | Class I Phosphatidylinositol 3-Kinases - genetics | Receptor, ErbB-2 - genetics | Colorectal Neoplasms - genetics | Humans | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Tomography, X-Ray Computed | Protein Kinase Inhibitors - adverse effects | Time Factors | DNA Mutational Analysis | Clinical Decision-Making | Colorectal Neoplasms - drug therapy | Female | Adenocarcinoma - genetics | Receptor, ErbB-2 - antagonists & inhibitors | Tumor Cells, Cultured | Liver Neoplasms - secondary | Lapatinib - adverse effects | Liver Neoplasms - genetics | Risk Factors | Liver Neoplasms - drug therapy | Trastuzumab - adverse effects | Mice, Transgenic | Treatment Outcome | Colorectal Neoplasms - diagnostic imaging | Trastuzumab - administration & dosage | Mice, SCID | Adenocarcinoma - drug therapy | Liver Neoplasms - diagnostic imaging | Adenocarcinoma - secondary | Disease Progression | Magnetic Resonance Imaging | Protein Kinase Inhibitors - administration & dosage | Drug Resistance, Neoplasm - genetics | Animals | Gene Amplification | Signal Transduction - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Progression-Free Survival | Italy | Mice, Inbred NOD | Adenocarcinoma - diagnostic imaging | Colorectal Neoplasms - pathology | Lapatinib - administration & dosage | Genetic research | Genetic aspects | Metastasis | Analysis | Colorectal cancer | Cancer
Journal Article
Archives of Pathology & Laboratory Medicine, ISSN 0003-9985, 12/2013, Volume 137, Issue 12, pp. 1707 - 1709
Journal Article
Histopathology, ISSN 0309-0167, 12/2013, Volume 63, Issue 6, pp. 869 - 876
Journal Article
International Journal of Surgical Pathology, ISSN 1066-8969, 8/2012, Volume 20, Issue 4, pp. 373 - 374
Journal Article
International Journal of Surgical Pathology, ISSN 1066-8969, 12/2012, Volume 20, Issue 6, pp. 596 - 597
Journal Article
Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia, 03/2013, Volume 30, Issue 2
Journal Article
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