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American Journal of Epidemiology, ISSN 0002-9262, 05/2015, Volume 181, Issue 9, pp. 733 - 734
Journal Article
by Brazel, David M and Jiang, Yu and Hughey, Jordan M and Turcot, Valérie and Zhan, Xiaowei and Gong, Jian and Batini, Chiara and Weissenkampen, J. Dylan and Liu, MengZhen and Liu, Dajiang J and Surendran, Praveen and Young, Robin and Barnes, Daniel R and Nielsen, Sune Fallgaard and Rasheed, Asif and Samuel, Maria and Zhao, Wei and Kontto, Jukka and Perola, Markus and Caslake, Muriel and de Craen, Anton J.M and Trompet, Stella and Uria-Nickelsen, Maria and Malarstig, Anders and Reily, Dermot F and Hoek, Maarten and Vogt, Thomas and Jukema, J. Wouter and Sattar, Naveed and Ford, Ian and Packard, Chris J and Alam, Dewan S and Majumder, Abdulla al Shafi and Di Angelantonio, Emanuele and Chowdhury, Rajiv and Amouyel, Philippe and Arveiler, Dominique and Blankenberg, Stefan and Ferrières, Jean and Kee, Frank and Kuulasmaa, Kari and Müller-Nurasyid, Martina and Veronesi, Giovanni and Virtamo, Jarmo and EPIC-CVD Consortium and Frossard, Philippe and Nordestgaard, Børge Grønne and Saleheen, Danish and Danesh, John and Butterworth, Adam S and Howson, Joanna M.M and Erzurumluoglu, A. Mesut and Jackson, Victoria E and Melbourne, Carl A and Varga, Tibor V and Warren, Helen R and Tragante, Vinicius and Tachmazidou, Ioanna and Harris, Sarah E and Evangelou, Evangelos and Marten, Jonathan and Zhang, Weihua and Altmaier, Elisabeth and Luan, Jian’an and Langenberg, Claudia and Scott, Robert A and Yaghootkar, Hanieh and Stirrups, Kathleen and Kanoni, Stavroula and Marouli, Eirini and Karpe, Fredrik and Dominiczak, Anna F and Sever, Peter and Poulter, Neil and Rolandsson, Olov and Baumbach, Clemens and Afaq, Saima and Chambers, John C and Kooner, Jaspal S and Wareham, Nicholas J and Renström, Frida and Hallmans, Göran and Marioni, Riccardo E and Corley, Janie and Starr, John M and Verweij, Niek and de Boer, Rudolf A and van der Meer, Peter and Yavas, Ersin and Vaartjes, Ilonca and Bots, Michiel L and Asselbergs, Folkert W and Grabe, Hans J and Völzke, Henry and Nauck, Matthias and Weiss, Stefan and Pharoah, Paul D.P and Dunning, Alison M and Dennis, Joe G and Thompson, Deborah J and ...
Biological Psychiatry, ISSN 0006-3223, 06/2019, Volume 85, Issue 11, pp. 946 - 955
Smoking and alcohol use have been associated with common genetic variants in multiple loci. Rare variants within these loci hold promise in the identification... 
Alcohol | Tobacco | Heritability | GWAS | Behavioral genetics | Nicotine
Journal Article
Journal Article
PLoS Genetics, ISSN 1553-7390, 10/2016, Volume 12, Issue 10
We performed an exome-wide association analysis in 1393 late-onset Alzheimer’s disease (LOAD) cases and 8141 controls from the CHARGE consortium. We found that... 
Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
American Journal of Epidemiology, ISSN 0002-9262, 12/2014, Volume 180, Issue 11, p. 1051
  Congenital deficiency of the proprotein convertase subtilisine/kexin type 1 gene (PCSK1), which encodes proprotein convertase 1/3, causes a severe... 
Proteins | Obesity | Body mass index | Congenital diseases | Genomics | Meta-analysis | Polymorphism
Journal Article
by Kanoni, Stavroula and Masca, Nicholas G D and Stirrups, Kathleen E and Varga, Tibor V and Warren, Helen R and Scott, Robert A and Southam, Lorraine and Zhang, Weihua and Yaghootkar, Hanieh and Müller-Nurasyid, Martina and Alves, Alexessander Couto and Strawbridge, Rona J and Lataniotis, Lazaros and Hashim, Nikman An and Besse, Céline and Boland, Anne and Braund, Peter S and Connell, John M and Dominiczak, Anna and Farmaki, Aliki-Eleni and Franks, Stephen and Grallert, Harald and Jansson, Jan-Håkan and Karaleftheri, Maria and Keinänen-Kiukaanniemi, Sirkka and Matchan, Angela and Pasko, Dorota and Peters, Annette and Poulter, Neil and Rayner, Nigel W and Renström, Frida and Rolandsson, Olov and Sabater-Lleal, Maria and Sennblad, Bengt and Sever, Peter and Shields, Denis C and Silveira, Angela and Stanton, Alice V and Strauch, Konstantin and Tomaszewski, Maciej and Tsafantakis, Emmanouil and Waldenberger, Melanie and Blakemore, Alexandra I. F and Dedoussis, George and Escher, Stefan A and Kooner, Jaspal S and McCarthy, Mark I and Palmer, Colin N. A and Hamsten, Anders and Caulfield, Mark J and Frayling, Timothy M and Tobin, Martin D and Jarvelin, Marjo Riitta and Zeggini, Eleftheria and Gieger, Christian and Chambers, John C and Wareham, Nick J and Munroe, Patricia B and Franks, Paul W and Samani, Nilesh J and Deloukas, Panos and EpiHealth: Epidemiology for Health and Lund University and Genetic and Molecular Epidemiology and Genetisk och molekylär epidemiologi and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
Human Molecular Genetics, ISSN 0964-6906, 2016, Volume 25, Issue 18, p. 4094
It has been hypothesized that low frequency (1-5% minor allele frequency (MAF)) and rare (<1% MAF) variants with large effect sizes may contribute to the... 
Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
International Journal of Epidemiology, ISSN 0300-5771, 2017, Volume 46, Issue 4, p. 1211
Journal Article
by Webb, Thomas R and Erdmann, Jeanette and Stirrups, Kathleen E and Stitziel, Nathan O and Masca, Nicholas G D and Jansen, Henning and Kanoni, Stavroula and Nelson, Christopher P and Ferrario, Paola G and König, Inke R and Eicher, John D and Johnson, Andrew D and Hamby, Stephen E and Betsholtz, Christer and Ruusalepp, Arno and Franzén, Oscar and Schadt, Eric and Björkegren, Johan L M and Weeke, Peter E and Auer, Paul L and Schick, Ursula M and Lu, Yingchang and Zhang, He and Dube, Marie Pierre and Goel, Anuj and Farrall, Martin and Peloso, Gina M and Won, Hong-Hee and Do, Ron and van Iperen, Erik Pa and Kruppa, Jochen and Mahajan, Anubha and Scott, Robert A and Willenborg, Christina and Braund, Peter S and Van Capelleveen, Julian C and Doney, Alex S F and Donnelly, Louise A and Asselta, Rosanna and Merlini, Pier Angelica and Duga, Stefano and Marziliano, Nicola and Denny, Josh C and Shaffer, Christian M and El Mokhtari, Nour Eddine and Franke, Andre and Heilmann, Stefanie and Hengstenberg, Christian and Hoffmann, Per and Holmen, Oddgeir L and Hveem, Kristian and Jansson, Jan-Håkan and Jöckel, Karl-Heinz and Kessler, Thorsten and Kriebel, Jennifer and Laugwitz, Karl L and Marouli, Eirini and Martinelli, Nicola and McCarthy, Mark I and van Zuydam, Natalie R and Meisinger, Christa and Esko, Tõnu and Mihailov, Evelin and Escher, Stefan A and Alver, Maris and Moebus, Susanne and Morris, Andrew D and Virtamo, Jarma and Nikpay, Majid and Olivieri, Oliviero and Provost, Sylvie and AlQarawi, Alaa and Robertson, Neil R and Akinsansya, Karen O and Reilly, Dermot F and Vogt, Thomas F and Yin, Wu and Asselbergs, Folkert W and Kooperberg, Charles and Jackson, Rebecca D and Stahl, Eli A and Müller-Nurasyid, Martina and Strauch, Konstantin and Varga, Tibor V and Waldenberger, Melanie and Zeng, Lingyao and Chowdhury, Rajiv and Salomaa, Veikko and Ford, Ian and Jukema, J. Wouter and Amouyel, Philippe and Kontto, Jukka and Nordestgaard, Børge G and Ferrières, Jean and Saleheen, Danish and Sattar, Naveed and Surendran, Praveen and Wagner, Aline and Young, Robin and Howson, Joanna M. M and ... and Diabetes - Cardiovascular Disease and Diabetes - kardiovaskulär sjukdom and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Lund University and EpiHealth: Epidemiology for Health and Genetic and Molecular Epidemiology and Genetisk och molekylär epidemiologi and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden
Journal of the American College of Cardiology, ISSN 0735-1097, 02/2017, Volume 69, Issue 7, p. 823
Background Genome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show pleiotropy;... 
Kardiologi | expression quantitative trait loci | Clinical Medicine | Cardiac and Cardiovascular Systems | genetics | Medical and Health Sciences | single nucleotide polymorphism | Medicin och hälsovetenskap | cholesteryl ester transfer protein | genome-wide association | Klinisk medicin
Journal Article
by Scott, Robert A and Lagou, Vasiliki and Welch, Ryan P and Wheeler, Eleanor and Montasser, May E and Luan, Jian'an and Mägi, Reedik and Strawbridge, Rona J and Rehnberg, Emil and Gustafsson, Stefan and Kanoni, Stavroula and Rasmussen-Torvik, Laura J and Yengo, Loïc and Lecoeur, Cecile and Shungin, Dmitry and Sanna, Serena and Sidore, Carlo and Johnson, Paul C. D and Jukema, J. Wouter and Johnson, Toby and Mahajan, Anubha and Verweij, Niek and Thorleifsson, Gudmar and Hottenga, Jouke-Jan and Shah, Sonia and Smith, Albert V and Sennblad, Bengt and Gieger, Christian and Salo, Perttu and Perola, Markus and Timpson, Nicholas J and Evans, David M and Pourcain, Beate St and Wu, Ying and Anews, Jeanette S and Hui, Jennie and Bielak, Lawrence F and Zhao, Wei and Horikoshi, Momoko and Navarro, Pau and Isaacs, Aaron and O'Connell, Jeffrey R and Stirrups, Kathleen and Vitart, Veronique and Hayward, Caroline and Esko, Tõnu and Mihailov, Evelin and Fraser, Ross M and Fall, Tove and Voight, Benjamin F and Raychaudhuri, Soumya and Chen, Han and Lindgren, Cecilia M and Morris, Anew P and Rayner, Nigel W and Robertson, Neil and Rybin, Denis and Liu, Ching-Ti and Beckmann, Jacques S and Willems, Sara M and Chines, Peter S and Jackson, Anne U and Kang, Hyun Min and Stringham, Heather M and Song, Kijoung and Tanaka, Toshiko and Peden, John F and Goel, Anuj and Hicks, Anew A and An, Ping and Müller-Nurasyid, Martina and Franco-Cereceda, Anders and Folkersen, Lasse and Marullo, Letizia and Jansen, Hanneke and Oldehinkel, Albertine J and Bruinenberg, Marcel and Pankow, James S and North, Kari E and Forouhi, Nita G and Loos, Ruth J. F and Edkins, Sarah and Varga, Tibor V and Hallmans, Göran and Oksa, Heikki and Antonella, Mulas and Nagaraja, Ramaiah and Trompet, Stella and Ford, Ian and Bakker, Stephan J. L and Kong, Augustine and Kumari, Meena and Gigante, Bruna and Herder, Christian and Munroe, Patricia B and Caulfield, Mark and Antti, Jula and Mangino, Massimo and Small, Kerrin and Miljkovic, Iva and ... and DIAbet Genetics Replication and DIAbetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium and Medicinska fakulteten and Institutionen för odontologi and Institutionen för folkhälsa och klinisk medicin and Näringsforskning and Umeå universitet and Medicin
Nature genetics, ISSN 1061-4036, 2012, Volume 44, Issue 9, pp. 991 - +
Journal Article
American Journal of Epidemiology, ISSN 0002-9262, 07/2013, Volume 178, Issue 1, p. 31
  A genetic variant within the CHRNA5-CHRNA3-CHRNB4 region (rs1051730), previously associated with smoking quantity, was recently shown to interact with... 
Obesity | Body mass index | Genetics | Adults | Smoking | Polymorphism
Journal Article
by Stitziel, Nathan O and Stirrups, Kathleen E and Masca, Nicholas G D and Erdmann, Jeanette and Ferrario, Paola G and König, Inke R and Weeke, Peter E and Webb, Thomas R and Auer, Paul L and Schick, Ursula M and Lu, Yingchang and Zhang, He and Dube, Marie-Pierre and Goel, Anuj and Farrall, Martin and Peloso, Gina M and Won, Hong-Hee and Do, Ron and van Iperen, Erik and Kanoni, Stavroula and Kruppa, Jochen and Mahajan, Anubha and Scott, Robert A and Willenberg, Christina and Braund, Peter S and van Capelleveen, Julian C and Doney, Alex S F and Donnelly, Louise A and Asselta, Rosanna and Merlini, Piera A and Duga, Stefano and Marziliano, Nicola and Denny, Josh C and Shaffer, Christian M and El-Mokhtari, Nour Eddine and Franke, Ane and Gottesman, Omri and Heilmann, Stefanie and Hengstenberg, Christian and Hoffman, Per and Holmen, Oddgeir L and Hveem, Kristian and Jansson, Jan-Håkan and Jöckel, Karl-Heinz and Kessler, Thorsten and Kriebel, Jennifer and Laugwitz, Karl L and Marouli, Eirini and Martinelli, Nicola and McCarthy, Mark I and Van Zuydam, Natalie R and Meisinger, Christa and Esko, Tõnu and Mihailov, Evelin and Escher, Stefan A and Alvar, Maris and Moebus, Susanne and Morris, Anew D and Müller-Nurasyid, Martina and Nikpay, Majid and Olivieri, Oliviero and Lemieux Perreault, Louis-Philippe and AlQarawi, Alaa and Robertson, Neil R and Akinsanya, Karen O and Reilly, Dermot F and Vogt, Thomas F and Yin, Wu and Asselbergs, Folkert W and Kooperberg, Charles and Jackson, Rebecca D and Stahl, Eli and Strauch, Konstantin and Varga, Tibor V and Waldenberger, Melanie and Zeng, Lingyao and Kraja, Aldi T and Liu, Chunyu and Ehret, George B and Newton-Cheh, Christopher and Chasman, Daniel I and Chowdhury, Rajiv and Ferrario, Marco and Ford, Ian and Jukema, J Wouter and Kee, Frank and Kuulasmaa, Kari and Nordestgaard, Børge G and Perola, Markus and Saleheen, Danish and Sattar, Naveed and Surenan, Praveen and Tregouet, David and Young, Robin and Howson, Joanna M M and Butterworth, Adam S and Danesh, John and Ardissino, Diego and Bottinger, Erwin P and Erbel, Raimund and ... and Diabetes - kardiovaskulär sjukdom and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Kansli för kliniska vetenskaper, Lund and EpiHealth: Epidemiology for Health and Institutionen för kliniska vetenskaper, Malmö and Genetisk och molekylär epidemiologi and Lunds universitet and Diabetes - Cardiovascular Disease and Lund University and Department Office of Clinical Sciences, Lund and Genetic and Molecular Epidemiology and EXODIAB: Excellence in Diabetes Research in Sweden and Department of Clinical Sciences, Malmö
New England Journal of Medicine, ISSN 0028-4793, 02/2016, Volume 374, Issue 12, p. 1134
BACKGROUND: The discovery of low-frequency coding variants affecting the risk of coronary artery disease has facilitated the identification of therapeutic... 
Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Circulation: Cardiovascular Genetics, ISSN 1942-325X, 04/2016, Volume 9, Issue 2, pp. 162 - 171
Journal Article