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1. Full Text Systematic Analysis of Splice-Site-Creating Mutations in Cancer
by Jayasinghe, Reyka G and Cao, Song and Gao, Qingsong and Gao, Jianjiong and Gao, Galen F and Wendl, Michael C and Vo, Nam Sy and Reynolds, Sheila and Reynolds, Sheila M and Zhao, Fengmei and Zhao, Yanyan and Climente-González, Héctor and Chai, Shengjie and Wang, Zhining and Wang, Fang and Wang, Min and Wang, Jing and Wang, Timothy and Wang, Linghua and Wang, Jioajiao and Varghese, Rajees and Huang, Mo and Liang, Wen-Wei and Liang, Han and Wyczalkowski, Matthew A and Sengupta, Sohini and Li, Zhi and Li, Wei and Li, Jun and Payne, Samuel H and Fenyö, David and Miner, Jeffrey H and Walter, Matthew J and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Yang, Liming and Yang, Ju Dong and Yang, Ian and Yang, Hannah and Zenklusen, Jean C and Zhang, Hailei and Zhang, Wei and Zhang, Jiashan (Julia) and Zhang, Lizhi and Zhang, Jiexin and Zhang, Hongxin and Zhang, Hongzheng and Chudamani, Sudha and Liu, Wenbin and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Michael and Miller, Judy and Miller, Christopher A and Shmulevich, Ilya and Thorsson, Vesteinn and Akbani, Rehan and Broom, Bradley M and Hegde, Apurva M and Ju, Zhenlin and Kanchi, Rupa S and Korkut, Anil and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Ng, Kwok-Shing and Rao, Arvind and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Cell Reports, ISSN 2211-1247, 04/2018, Volume 23, Issue 1, pp. 270 - 281.e3
For the past decade, cancer genomic studies have focused on mutations leading to splice-site disruption, overlooking those having splice-creating potential.... 
RNA | mutations of clinical relevance | splicing | BREAST-CANCER | INACTIVATION | RETINOBLASTOMA | REPORTER MINIGENE | MESSENGER-RNA | TRANSCRIPTOME | UNCLASSIFIED VARIANTS | GENETIC-VARIANTS | ABERRANT | SYNONYMOUS MUTATIONS | CELL BIOLOGY | Index Medicus | Splicing | Mutations of clinical relevance | BASIC BIOLOGICAL SCIENCES
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2. Full Text Abstract 3424: Genomic alterations in clonal hematopoiesis
by Huang, Kuan-Lin and Xie, Mingchao and Wu, Yige and Jayasinghe, Reyka and Varghese, Rajees and Mashl, R. Jay and Cao, Song and Wyczalkowski, Matthew and Liang, Wen-wei and Wendel, Michael C and Fields, Ryan and McLellan, Michael D and Link, Daniel C and Chen, Feng and Ding, Li
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 3424 - 3424
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3. Full Text Integrative omics analyses broaden treatment targets in human cancer
by Sengupta, Sohini and Sun, Sam Q and Huang, Kuan-lin and Oh, Clara and Bailey, Matthew H and Varghese, Rajees and Wyczalkowski, Matthew A and Ning, Jie and Tripathi, Piyush and McMichael, Joshua F and Johnson, Kimberly J and Kandoth, Cyriac and Welch, John and Ma, Cynthia and Wendl, Michael C and Payne, Samuel H and Fenyö, David and Townsend, Reid R and Dipersio, John F and Chen, Feng and Ding, Li and Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Genome Medicine, ISSN 1756-994X, 07/2018, Volume 10, Issue 1, pp. 60 - 60
Background: Although large-scale, next-generation sequencing (NGS) studies of cancers hold promise for enabling precision oncology, challenges remain in... 
Precision medicine | Proteogenomics | Cancer and druggability | Cancer genomics | Multi-omics | DRUG-SENSITIVITY | PHASE-II | ESTROGEN-RECEPTOR | SOMATIC MUTATIONS | CELL LUNG-CANCER | BREAST-CANCER | GROWTH-FACTOR RECEPTOR | COLORECTAL-CANCER | PROTEOGENOMIC CHARACTERIZATION | GENETICS & HEREDITY | GENOMIC ALTERATIONS | Humans | Male | Neoplasms - drug therapy | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Neoplasms - genetics | Proto-Oncogene Proteins B-raf - genetics | HEK293 Cells | Pharmacogenomic Variants | Female | Biomarkers, Tumor - genetics | Mutation | Genomics - methods | Molecular Targeted Therapy - methods | Precision Medicine - methods | Proto-Oncogene Proteins B-raf - metabolism | Usage | Research | Biological markers | Drug therapy | Phosphoproteins | Cancer | TOR protein | AKT protein | Breast cancer | Kinases | Drug screening | Gene expression | Cancer therapies | 1-Phosphatidylinositol 3-kinase | ESR1 protein | Next-generation sequencing | Computer applications | Biomarkers | Protein structure | Tumors | Index Medicus | cancer and druggability | cancer genomics | mult-omics | precision medicine | 60 APPLIED LIFE SCIENCES | proteogenomics
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