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Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 10/2019, Volume 29, Issue 19, p. 126633
The enzyme geranylgeranyl diphosphate synthase (GGDPS) is a potential therapeutic target for multiple myeloma. Malignant plasma cells produce and secrete large... 
Triazole | Bisphosphonate | Inhibition | GGDP synthase | Isoprenoid biosynthesis
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. LB-45 - LB-45
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 2157 - 2157
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 2632 - 2632
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 4968 - 4968
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 2738 - 2738
Journal Article
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. 3484 - 3484
Journal Article
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. 2328 - 2328
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 3486 - 3486
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 733 - 733
Journal Article
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. 305 - 305
Journal Article
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. 1180 - 1180
Journal Article
The Journal of pharmacology and experimental therapeutics, 08/2019
The enzyme geranylgeranyl diphosphate synthase (GGDPS) synthesizes the 20-carbon isoprenoid geranylgeranyl diphosphate (GGPP) which is used in... 
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 1507 - 1507
Journal Article
American Journal of Clinical Pathology, ISSN 0002-9173, 2006, Volume 125, Issue 2, pp. 209 - 216
Journal Article
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. 2281 - 2281
Journal Article
Cancer Letters, ISSN 0304-3835, 2015, Volume 372, Issue 2, pp. 192 - 200
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 693 - 693
Journal Article
The Journal of Immunology, ISSN 0022-1767, 03/2003, Volume 170, Issue 6, pp. 3369 - 3376
IL-8, a member of the chemokine family, has been shown to play an important role in tumor growth, angiogenesis, and metastasis. The objective of this study was... 
CARCINOMA-CELLS | C-X-C | BCL-X | HUMAN-MELANOMA CELLS | NON-HODGKINS-LYMPHOMA | MALIGNANT-MELANOMA | IMMUNOLOGY | TUMOR-GROWTH | HUMAN INTERLEUKIN-8 | EXPRESSION | CANCER | Endothelium, Vascular - cytology | Matrix Metalloproteinases - genetics | Receptors, Interleukin-8A - biosynthesis | Humans | Receptors, Interleukin-8A - genetics | Cell Survival - genetics | Apoptosis - genetics | Interleukin-8 - physiology | Endothelium, Vascular - enzymology | Cell Movement - genetics | Capillaries - physiology | Cell Movement - immunology | RNA, Messenger - biosynthesis | Cell Division - immunology | Matrix Metalloproteinase 9 - genetics | Interleukin-8 - metabolism | Matrix Metalloproteinase 2 - biosynthesis | Endothelium, Vascular - immunology | Matrix Metalloproteinases - biosynthesis | Cell Division - genetics | Receptors, Interleukin-8B - physiology | Recombinant Proteins - metabolism | Cell Line | Matrix Metalloproteinase 9 - biosynthesis | Neovascularization, Physiologic - genetics | Up-Regulation - genetics | Recombinant Proteins - pharmacology | Cell Survival - immunology | Neovascularization, Physiologic - immunology | Down-Regulation - genetics | Matrix Metalloproteinase 2 - genetics | Apoptosis - immunology | Receptors, Interleukin-8B - biosynthesis | Up-Regulation - immunology | Down-Regulation - immunology | Endothelium, Vascular - metabolism | Receptors, Interleukin-8B - genetics | Receptors, Interleukin-8A - physiology
Journal Article
BMC Cancer, ISSN 1471-2407, 12/2018, Volume 18, Issue 1, pp. 1283 - 15
BackgroundPancreatic cancer (PC) is a highly aggressive disease, and the lethality of this disease stems from early metastatic dissemination where surgical... 
Semaphorin-5A | Epithelial-to-mesenchymal transition (EMT) | Pancreatic cancer | Tumor growth and metastasis | SYSTEM | METASTASIS | GLYCOGEN-SYNTHASE KINASE-3 | INHIBITION | ONCOLOGY | GROWTH | TRANSITIONS | RAC1 | EXPRESSION | MOTILITY | Treatment outcome | Cancer patients | Care and treatment | Semaphorins | Analysis | Development and progression | Genetic aspects | Research | Gene expression | Health aspects
Journal Article
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