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Journal Article
Gene therapy, ISSN 0969-7128, 02/2019
The carcinoembryonic antigen (CEA) is the main tumor-associated antigen of colorectal cancers. Previously, we developed a DNA vaccine using scFv6.C4, a CEA... 
Journal Article
Orthodontics & Craniofacial Research, ISSN 1601-6335, 08/2019, Volume 22, Issue 3, pp. 222 - 223
Journal Article
Microbiology and Immunology, ISSN 0385-5600, 04/2006, Volume 50, Issue 4, pp. 253 - 263
In the present work we investigated the role of killed Propionibacterium acnes or a soluble polysaccharide extracted from bacterium cell wall in modulated... 
immunomodulation | propionibacterium acnes | trypanosoma cruzi | DNA immunization | Propionibacterium acnes | Immunomodulation | Trypanosoma cruzi | PROTEIN | ANTIBODY | MICROBIOLOGY | IMMUNOLOGY | IL-18 PRODUCTION | CUTTING EDGE | PROTECTIVE IMMUNITY | DENDRITIC CELL PRECURSORS | MICE | INFECTION | CORYNEBACTERIUM-PARVUM | TRANS-SIALIDASE | Antibody Specificity | Vaccines, DNA - genetics | Chagas Disease - immunology | Spleen - immunology | Immunoglobulin G - blood | Vaccines, DNA - immunology | Neuraminidase - genetics | Male | Th2 Cells - immunology | Th1 Cells - immunology | Chagas Disease - prevention & control | Neuraminidase - immunology | Immunoglobulin G - immunology | Polysaccharides - isolation & purification | Plasmids - genetics | Female | Propionibacterium acnes - chemistry | Trypanosoma cruzi - immunology | Propionibacterium acnes - immunology | Protozoan Vaccines - genetics | Protozoan Vaccines - immunology | Lymphocyte Activation | Parasitemia - immunology | Plasmids - immunology | Trypanosoma cruzi - genetics | Th2 Cells - cytology | Polysaccharides - immunology | Immunoglobulin Isotypes - blood | Animals | Interferon-gamma - immunology | Parasitemia - prevention & control | Parasitemia - parasitology | Immunoglobulin Isotypes - immunology | Mice | Mice, Inbred BALB C | Th1 Cells - cytology | Interferon-gamma - biosynthesis
Journal Article
Immunology and Cell Biology, ISSN 0818-9641, 04/2003, Volume 81, Issue 2, pp. 121 - 129
BALB/c or C57Bl/6 mice immunized with plasmids containing Trypanosoma cruzi genes developed specific immune responses and protective immunity against lethal... 
DNA immunization | recombinant protein | protozoan parasites | Protozoan parasites | Recombinant protein | CONFERS PROTECTION | ELICITS | CPG-DNA | VACCINATION | DEFICIENT MICE | IMMUNOLOGY | CELL BIOLOGY | IMMUNIZATION | GENE | PLASMID DNA | TRANS-SIALIDASE | ANTIGEN | Recombinant Proteins - therapeutic use | Neuraminidase - administration & dosage | Disease Susceptibility | Immunization - methods | Neuraminidase - therapeutic use | Trypanosoma cruzi - genetics | Neuraminidase - genetics | DNA, Protozoan - therapeutic use | Survival Rate | Glycoproteins | Mice, Inbred Strains | Chagas Disease - prevention & control | Vaccines, DNA - administration & dosage | Recombinant Proteins - administration & dosage | Animals | Immunity, Cellular - drug effects | Antibody Formation - drug effects | Chagas Disease - therapy | Mice | Trypanosoma cruzi - chemistry | Chagas Disease, prevention and control | Neuraminidase, genetics | Recombinant Proteins, administration and dosage | Recombinant Proteins, therapeutic use | Immunization, methods | Vaccines, DNA, administration and dosage | Trypanosoma cruzi, genetics | Neuraminidase, administration and dosage | Neuraminidase, therapeutic use | Trypanosoma cruzi, chemistry | Immunity, Cellular, drug effects | Antibody Formation, drug effects | DNA, Protozoan, therapeutic use | Chagas Disease, therapy
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 7, p. e22011
During adaptive immune response, pathogen-specific CD8(+) T cells recognize preferentially a small number of epitopes, a phenomenon known as immunodominance.... 
PROTECTIVE IMMUNITY | SUSCEPTIBLE MOUSE STRAIN | BIOLOGY | CHAGAS HEART-DISEASE | PRECURSOR FREQUENCIES | IMMUNODOMINANCE HIERARCHY | AMASTIGOTE SURFACE PROTEIN-2 | ADHESION MOLECULES | TRYPANOSOMA-CRUZI INFECTION | TRANS-SIALIDASE | DOMINANT EPITOPE | Immunodominant Epitopes - immunology | Interleukin-2 - metabolism | Tumor Necrosis Factor-alpha - metabolism | Peptides - chemistry | Immunodominant Epitopes - chemistry | Humans | Peptides - immunology | Epitopes, T-Lymphocyte - genetics | Interferon-gamma - metabolism | Epitopes, T-Lymphocyte - chemistry | Animals | CD8-Positive T-Lymphocytes - metabolism | Interleukin-10 - metabolism | Female | Mice | Epitopes, T-Lymphocyte - immunology | Immunodominant Epitopes - genetics | Trypanosoma cruzi - microbiology | CD8-Positive T-Lymphocytes - immunology | Infection | Gene mutations | Adenoviruses | Vaccination | Vaccines | T cells | Health aspects | Antigenic determinants | Peptides | CD8 antigen | Infections | Lymphocytes T | DNA vaccines | Histocompatibility antigen H-2 | trans-Sialidase | Parasites | Immunodominance | Immunity | Tropical diseases | Proteins | Lymphocytes | Plasmid DNA | Deoxyribonucleic acid--DNA | Recombinant | Immune system | Pathogens | Protozoa | Antigens | Immunization | Immune response | Malaria | T cell receptors | Epitopes | Hypotheses | Experimental infection | Parasitism | Endoplasmic reticulum | Deoxyribonucleic acid | DNA
Journal Article
Frontiers in cellular and infection microbiology, ISSN 2235-2988, 2018, Volume 8, p. 426
Toll-like receptors (TLRs) comprise the best-characterized pattern-recognition receptor (PRR) family able to activate distinct immune responses depending on... 
paracoccidioidomycosis | CD8+T cells | cytotoxic | TLR3 | Paracoccidioides brasiliensis | ASPERGILLUS-FUMIGATUS | ACTIVATION | DENDRITIC CELLS | MACROPHAGES | TOLL-LIKE RECEPTOR | MICROBIOLOGY | IMMUNOLOGY | DECTIN-1 | CD8(+) T cells | INFECTION | PATTERN-RECOGNITION RECEPTORS | T-CELLS | INNATE IMMUNITY
Journal Article