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Molecules, ISSN 1420-3049, 10/2016, Volume 21, Issue 10, pp. 1269 - 1269
Journal Article
Molecules, ISSN 1420-3049, 10/2017, Volume 22, Issue 10, p. 1773
The most important components of Plantago lanceolata L. leaves are catalpol, aucubin, and acteoside (=verbascoside). These bioactive compounds possess... 
Plantago lanceolata | Caco-2 cells | Cytotoxicity investigation | SNEDDS | Antioxidant and anti-inflammatory effects | DPPH test | MTT-test | CELLS | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACTEOSIDE | MODEL | FREE-RADICAL METHOD | IN-VITRO CYTOTOXICITY | CHEMISTRY, MULTIDISCIPLINARY | DAMAGE | cytotoxicity investigation | VERBASCOSIDE | ABSORPTION | antioxidant and anti-inflammatory effects | EXTRACT | Caco-2 Cells | Plant Leaves - chemistry | Xylenes - adverse effects | Cell Survival - drug effects | Plant Extracts - chemistry | Emulsions | Antioxidants - chemistry | Nanoparticles - chemistry | Anti-Inflammatory Agents - pharmacology | Plant Extracts - pharmacology | Humans | Ear Diseases - chemically induced | Edema - drug therapy | Antioxidants - pharmacology | Ear Diseases - drug therapy | Hydrolysis | Particle Size | Plant Extracts - administration & dosage | Animals | Anti-Inflammatory Agents - chemistry | Plantago - chemistry | Antioxidants - administration & dosage | Anti-Inflammatory Agents - administration & dosage | Edema - chemically induced | Edema | Drug delivery systems | Statistical analysis | Toxicity | Cytotoxicity | Plant protection | Pharmacology | Inflammation | Statistical methods | Drug delivery | Physical properties | Dissolution | Composition effects | Antioxidants | Dilution | Bioactive compounds | Biocompatibility | In vivo methods and tests | Viability | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, p. e0170537
Alpha-melanocyte-stimulating hormone (alpha-MSH) is a potent anti-inflammatory peptide with cytoprotective effect in various tissues. The present investigation... 
ACTIVATION | MSH | PERMEABILITY | MECHANISM | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | TNF-ALPHA | MODEL | NF-KAPPA-B | MODULATION | Caco-2 Cells | Intestinal Mucosa - metabolism | Permeability - drug effects | alpha-MSH - pharmacology | Humans | NF-kappa B - metabolism | Electric Impedance | Receptor, Melanocortin, Type 1 - metabolism | Intestinal Mucosa - drug effects | Interleukin-1beta - administration & dosage | Cytoprotection - drug effects | Claudin-4 - metabolism | Tumor Necrosis Factor-alpha - administration & dosage | Inflammation - prevention & control | Intestinal Mucosa - injuries | Interleukin-8 - metabolism | Zonula Occludens-1 Protein - metabolism | Interleukin-6 - metabolism | Usage | Cytokines | Tumor necrosis factor | Analysis | Inflammation | Intermedin | Health aspects | Fluorescence microscopy | Immunohistochemistry | Cell culture | Flow cytometry | Melanocyte-stimulating hormone | Disease | Epithelial cells | Interleukin | Fluorescence | Activation | Kinases | Tissues | Small intestine | Inflammatory diseases | Interleukin 6 | Proteins | Immunology | Ischemia | Intestine | Rodents | Tumor necrosis factor-TNF | a-Melanocyte-stimulating hormone | Interleukin 8 | Pharmaceutical sciences | Translocation | NF-κB protein | Melanocortin | Exposure | Biophysics | Permeability | Tumor necrosis factor-α | Zonula occludens-1 protein | Nuclear transport | Studies | Inflammatory bowel disease | Pharmacy | Fluorescein | Monolayers | Nuclei (cytology)
Journal Article
Nutrients, ISSN 2072-6643, 07/2018, Volume 10, Issue 7, p. 861
Anthocyanins have several beneficial effects, especially on inflammatory and oxidative conditions. The pro-inflammatory cytokines, tumor necrosis factor-alpha... 
Anthocyanin | NF-κB | Inflammation | Permeability | Sour cherry | Caco-2 | sour cherry | FRUITS | ACTIVATION | permeability | BARRIER | PRUNUS-CERASUS L | LESIONS | NUTRITION & DIETETICS | NF-kappa B | inflammation | ANTIOXIDANT | anthocyanin | CELL-LINE | MODULATION | Interleukin-1beta - pharmacology | Anthocyanins - isolation & purification | Plant Extracts - pharmacology | Humans | Colon - drug effects | Inflammatory Bowel Diseases - metabolism | Dose-Response Relationship, Drug | Time Factors | Anti-Inflammatory Agents - isolation & purification | Active Transport, Cell Nucleus | Interleukin-8 - metabolism | Phytotherapy | Interleukin-6 - metabolism | Caco-2 Cells | Glutathione Peroxidase - metabolism | Anthocyanins - pharmacology | Inflammatory Bowel Diseases - prevention & control | Fruit | Anti-Inflammatory Agents - pharmacology | Plant Extracts - isolation & purification | Electric Impedance | Colon - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Transcription Factor RelA - metabolism | Prunus avium - chemistry | Plants, Medicinal | Inflammatory bowel diseases | Pathogenesis | Interleukin | Nuclear engineering | Small intestine | Fruits | Interleukin 6 | Biological effects | Intestine | Bowel disease | Tumor necrosis factor-TNF | Peroxidase | Interleukin 8 | Glutathione | Formulations | Glutathione peroxidase | Translocation | NF-κB protein | Cytokines | Tumor necrosis factor-α | Biological activity | Nuclear transport | Nuclear safety | Monolayers | Anthocyanins
Journal Article
Synlett, ISSN 0936-5214, 04/2019, Volume 30, Issue 7, pp. 799 - 802
Abstract Ethyl-3-formyl-6-methoxy-(2 H )-chromene-2-carboxylate was transformed to N -substituted 1,2-dihydrochromeno[2,3-c]pyrrol-3-ones in a domino reductive... 
letter | 1 | 2-dihydrochromeno | RHODODAURICHROMANIC ACID-A | isomerization | HPLC-ECD | CHROMANE DERIVATIVES | CHEMISTRY, ORGANIC | 3-c]pyrrol-3-one | antiproliferative | DOMINO | TDDFT-ECD
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 02/2019, Volume 128, pp. 202 - 208
A new renaissance started in the research and application of cyclodextrins a few years ago. 2-Hydroxypropyl-beta-cyclodextrin (HPBCD) is used in the... 
Hydroxypropyl-beta-cyclodextrin | Pharmacokinetics | 68Ga | Positron emission tomography
Journal Article
Molecules, 11/2015, Volume 20, Issue 11, p. 20269
  Cyclodextrins, even the 6-membered α-cyclodextrin, are approved in the various pharmacopoeias as pharmaceutical excipients for solubilizing and stabilizing... 
Journal Article
by Małecki, Andrzej and Skipor-Lahuta, Janina and Toborek, Michal and Abbott, N. Joan and Antonetti, David A and Su, Enming Joe and Lawrence, Daniel A and Atış, Müge and Akcan, Uğur and Yılmaz, Canan Uğur and Orhan, Nurcan and Düzgün, Poyraz and Ceylan, Umut Deniz and Arıcan, Nadir and Karahüseyinoğlu, Serçin and Şahin, Gizem Nur and Ahıshalı, Bülent and Kaya, Mehmet and Aydin, Sidar and Klopstein, Armelle and Engelhardt, Britta and Baumann, Julia and Tsao, Chih-Chieh and Huang, Sheng-Fu and Ogunshola, Omolara and Boytsova, Elizaveta B and Morgun, Andrey V and Khilazheva, Elena D and Pozhilenkova, Elena A and Gorina, Yana V and Martynova, Galina P and Salmina, Alla B and Bueno, David and Garcia-Fernàndez, Jordi and Castro, Victor and Skowronska, Marta and Chupel, Matheus Uba and Minuzzi, Luciele Guerra and Filaire, Edith and Teixeira, Ana Maria and Corsi, Mariangela and Versele, Romain and Fuso, Andrea and Sevin, Emmanuel and Di Lorenzo, Cherubino and Businaro, Rita and Fenart, Laurence and Gosselet, Fabien and Candela, Pietra and Deli, Mária A and Delaney, Conor and O’Keefe, Eoin and Farrell, Michael and Doyle, Sarah and Campbell, Matthew and Drewes, Lester R and Appelt-Menzel, A and Cubukova, A and Metzger, M and Fischer, R and Francisco, David M. F and Bruggmann, Rémy and Fries, Alexa and Blecharz, Kinga G and Wagner, Josephin and Winkler, Lars and Schneider, Ulf and Vajkoczy, Peter and Furuse, Mikio and Gabbert, Lydia and Dilling, Christina and Sisario, Dmitri and Soukhoroukov, Vladimir and Burek, Malgorzata and Guérit, S and Fidan, E and Devraj, K and Czupalla, C. J and Macas, J and Thom, S and Plate, K. H and Gerhardt, H and Liebner, S and Harazin, András and Bocsik, Alexandra and Váradi, Judit and Fenyvesi, Ferenc and Tubak, Vilmos and Vecsernyés, Miklós and Helms, Hans Christian and Waagepetersen, Helle Sønderby and Nielsen, Carsten Uhd and Brodin, Birger and Hoyk, Zsófia and Tóth, Melinda E and Lénárt, Nikolett and Dukay, Brigitta and Kittel, Ágnes and Vígh, Judit and Veszelka, Szilvia and ...
Fluids and Barriers of the CNS, ISSN 2045-8118, 10/2017, Volume 14, Issue Suppl 2, pp. 1 - 23
Journal Article
AAPS PharmSciTech, ISSN 1530-9932, 10/2019, Volume 20, Issue 7, pp. 1 - 11
Dosage forms with increased gastric residence time are promising tools to increase bioavailability of drugs with narrow absorption window. Low-density floating... 
Biochemistry, general | Biotechnology | Biomedicine | solid foam | PEG 4000 | solid dispersion | Pharmacy | Pharmacology/Toxicology | gastric retention | lipid matrix | SUPERPOROUS HYDROGEL COMPOSITE | FORMULATION | BIOAVAILABILITY | TABLETS | IN-VITRO | DISSOLUTION | STEARIC-ACID | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | ABSORPTION | DRUG-DELIVERY SYSTEMS
Journal Article