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1. Full Text Cytotoxic CD4.sup.+ T-cells during HIV infection: Targets or weapons?
by Sanchez-Martinez, Alexandra and Perdomo-Celis, Federico and Acevedo-Saenz, Liliana and Rugeles, Maria T and Velilla, Paula A
Journal of Clinical Virology, ISSN 1386-6532, 10/2019, Volume 119, p. 17
Classically, CD4.sup.+ T-cells have been referred as cytokine-producing cells and important players in immune responses by providing soluble factors that... 
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2. Full Text An altered cytotoxic program of CD8.sup.+ T-cells in HIV-infected patients despite HAART-induced viral suppression.(Research Article)
by Perdomo-Celis, Federico and Velilla, Paula A and Taborda, Natalia A and Rugeles, Maria Teresa
PLoS ONE, ISSN 1932-6203, 01/2019, Volume 14, Issue 1, p. e0210540
Antiviral agents | Care and treatment | Immune response | Analysis | HIV patients | Dosage and administration | Research | T cells
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3. Full Text Male Ebola Survivors: Do Not Forget to Use a Condom
by Cardona-Maya, Walter D and Hernandez, Paula A. Velilla and Henao, Daniel E
Reproductive Sciences, ISSN 1933-7191, 10/2019, Volume 26, Issue 10, pp. 1326 - 1326
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4. Chikungunya Virus and Zika Virus, Two Different Viruses Examined with a Common Aim: Role of Pattern Recognition Receptors on the Inflammatory Response
by Lopez, JFV and Velilla, PA and Urcuqui-Inchima, S
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, ISSN 1079-9907, 09/2019, Volume 39, Issue 9, pp. 507 - 521
Chikungunya virus (CHIKV) and Zika virus (ZIKV) are 2 reemerging arboviruses that have been the focus of public health institutions worldwide, since the last... 
ACTIVATION | PROTEIN | RNA | PRRs | BIOCHEMISTRY & MOLECULAR BIOLOGY | INNATE IMMUNE-RESPONSE | RIG-I | IMMUNOLOGY | CELL BIOLOGY | ZIKV | ANTIVIRAL RESPONSES | REPLICATION | NOD-LIKE RECEPTORS | DISEASE | INFECTION | inflammation and arbovirus | CHIKV | Vector-borne diseases | Secretion | Outbreaks | Viruses | Inflammatory response | Zika virus | Arthritis | Inflammation | Pattern recognition | Neurological diseases | Receptors | Microencephaly | Interferon | Public health
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5. Full Text Role of Monocytes in the Pathogenesis of Dengue
by Castillo, Jorge Andrés and Castillo, Jorge Andrés and Naranjo, Juan Sebastián and Naranjo, Juan Sebastián and Rojas, Mauricio and Rojas, Mauricio and Castaño, Diana and Castaño, Diana and Velilla, Paula Andrea and Velilla, Paula Andrea
Archivum Immunologiae et Therapiae Experimentalis, ISSN 0004-069X, 2/2019, Volume 67, Issue 1, pp. 27 - 40
Diseases caused by dengue virus (DENV) are a major public health problem worldwide, considered one of the infections with more prevalence in tropical and... 
Dengue virus pathogenesis | Monocytes | Biomedicine | Immunology | Monocyte subpopulations | Endothelial permeability | Pharmacology/Toxicology | Dengue virus | HUMAN MONOCYTES/MACROPHAGES | VIRUS-INFECTION | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | ANTIBODY-DEPENDENT ENHANCEMENT | CIRCULATING LEVELS | IN-VITRO | HEMORRHAGIC-FEVER | ENDOTHELIAL-CELL PERMEABILITY | PERIPHERAL-BLOOD MONOCYTES | MONONUCLEAR PHAGOCYTES | Subpopulations | Cytokines | Viremia | Pathogenesis | Dengue | Infections | Inflammation | Permeability | Endothelium | Phagocytes | Subtropical zones | Peripheral blood | Microvasculature | Public health | Chemokines
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6. Full Text An altered cytotoxic program of CD8+ T-cells in HIV-infected patients despite HAART-induced viral suppression
by Perdomo-Celis, Federico and Velilla, Paula A and Taborda, Natalia A and Rugeles, María Teresa
PLoS ONE, ISSN 1932-6203, 01/2019, Volume 14, Issue 1, p. e0210540
Despite the suppression of viral replication induced by the highly active anti-retroviral therapy (HAART), an increased immune activation and inflammatory... 
EFFECTOR | PERFORIN EXPRESSION | CD8+T LYMPHOCYTES | MULTIDISCIPLINARY SCIENCES | ANTIRETROVIRAL THERAPY | HIV-1-INFECTED PATIENTS | CD38 EXPRESSION | MEMORY SUBSETS | GASTROINTESTINAL MUCOSA | HUMAN-IMMUNODEFICIENCY-VIRUS | GRANZYME-B | CD57 antigen | CD8 antigen | Effector cells | Cytotoxicity | Infections | Activation | Lymphocytes T | Highly active antiretroviral therapy | Cell activation | Granzyme B | Acquired immune deficiency syndrome--AIDS | Lymphocytes | Human immunodeficiency virus--HIV | Perforin | Antiretroviral drugs | Memory cells | Markers | Immune reconstitution | Inflammation | Patients | Computer memory | Exhaustion | Degranulation | Replication | Histocompatibility antigen HLA | Differentiation | Viral infections | Acquired immune deficiency syndrome | AIDS | HIV | Human immunodeficiency virus
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7. Full Text Dengue immunopathology: Importance and participation of monocytes and their subsets
by Naranjo Gómez, Juan Sebastián and Castillo Ramírez, Jorge Andrés and Velilla Hernández, Paula Andrea and Castaño Monsalve, Diana María
Iatreia, ISSN 0121-0793, 07/2019, Volume 32, Issue 3, pp. 204 - 216
Dengue is an acute viral infection transmitted by the bite of the mosquito belonging to the genus Aedes, which produce until 100 millions of infections... 
Monocytes | Dengue | Severe Dengue
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8. Full Text Inmunogenicidad potencial de epítopes mutados derivados de la proteína Gag de cepas de VIH-1 circulantes en Medellín: Evaluación funcional de células T CD8
by David Arcia and Liliana Acevedo-Sáenz and Paula Andrea Velilla
Iatreia, ISSN 0121-0793, 01/2019, Volume 32, p. S20
La infección por el virus de la inmunodeficiencia humana (VIH) representa uno de los principales problemas de salud pública. A la fecha, algunas estrategias... 
Histopathology | Lymphocytes | Human immunodeficiency virus--HIV
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9. Full Text Functional Regulatory T Cells Accumulate in Aged Hosts and Promote Chronic Infectious Disease Reactivation
by Lages, Celine S and Suffia, Isabelle and Velilla, Paula A and Huang, Bin and Warshaw, Gregg and Hildeman, David A and Belkaid, Yasmin and Chougnet, Claire
The Journal of Immunology, ISSN 0022-1767, 08/2008, Volume 181, Issue 3, pp. 1835 - 1848
Declines in immune function are well described in the elderly and are considered to contribute significantly to the disease burden in this population.... 
SUPPRESSIVE ACTIVITY | CYTOKINE PRODUCTION | TGF-BETA | LEISHMANIA-MAJOR INFECTION | DENDRITIC CELLS | LYMPHOCYTE SUBSETS | RETINOIC-ACID | REG-CELLS | IMMUNOLOGICAL SELF-TOLERANCE | PERIPHERAL-BLOOD | IMMUNOLOGY | Leishmania major - immunology | Cell Proliferation | Health | Humans | Mice, Inbred C57BL | Leishmaniasis, Cutaneous - immunology | T-Lymphocytes, Regulatory - immunology | Cell Movement - immunology | Aging - immunology | Phenotype | Animals | CD3 Complex - immunology | T-Lymphocytes, Regulatory - cytology | Antibodies - immunology | Biomarkers | Adult | Aged | Mice | Chronic Disease | Cytokines - biosynthesis | Cytokines - immunology
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10. Full Text Inmunopatología del dengue: importancia y participación de los monocitos y sus subpoblaciones
by Naranjo-Gómez, Juan Sebastián and Castillo-Ramírez, Jorge Andrés and Velilla-Hernández, Paula Andrea and Castaño-Monsalve, Diana Maria
Iatreia, ISSN 0121-0793, 02/2019, Volume 1, Issue 1
El dengue es una infección viral aguda transmitida por la picadura de mosquitos del género Aedes, la cual produce hasta 100 millones de infecciones anuales en... 
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11. Full Text Identification of mutations associated with resistance to integrase strand transfer inhibitors (INSTI) in ART-naïve HIV-1 patients in Medellin, Colombia
by Vanegas-Otálvaro, Daniela and Velilla, Paula A and Velasquez, Claudia P and Rugeles, Maria T and Diaz, Francisco J and Acevedo-Sáenz, Liliana
Infectio, ISSN 0123-9392, 2019, Volume 23, pp. 97 - 128
HIV-1 | HIV integrase | Mutation | Drug resistance
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12. Full Text Immunological Characterization of Compensatory Anti-Inflammatory Response Syndrome in Patients With Severe Sepsis: A Longitudinal Study
by Gomez, Henry G and Gonzalez, Sandra M and Londoño, Jessica M and Hoyos, Natalia A and Niño, Cesar D and Leon, Alba L and Velilla, Paula A and Rugeles, Maria T and Jaimes, Fabián A
Critical Care Medicine, ISSN 0090-3493, 04/2014, Volume 42, Issue 4, pp. 771 - 780
OBJECTIVES:To perform a complete immunological characterization of compensatory anti-inflammatory response syndrome in patients with sepsis and to explore the... 
immunosuppression | physio pathology | secondary infection | sepsis | survival | longitudinal studies | MORTALITY | ANTIINFLAMMATORY CYTOKINE PROFILE | IMMUNE DYSFUNCTIONS | PROGRAMMED DEATH-1 | MULTIPLE ORGAN FAILURE | HLA-DR EXPRESSION | CELL-DEATH | physiopathology | SEPTIC SHOCK PATIENTS | UP-REGULATION | T-LYMPHOCYTES | CRITICAL CARE MEDICINE | Inflammation Mediators - immunology | Intensive Care Units | Sepsis - immunology | Cell Proliferation | Prospective Studies | Comorbidity | Humans | Middle Aged | Inflammation Mediators - blood | Male | Leukocytes, Mononuclear - immunology | Female | Organ Dysfunction Scores | Aged | Sepsis - blood | HLA-DR Antigens - biosynthesis | Continental Population Groups | Longitudinal Studies | APACHE | Apoptosis
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13. Full Text Frequency and phenotype alterations in monocyte subsets from dengue patients
by Juan, Naranjo-Gomez and Jorge, Castillo and Paula, Velilla and Mauricio, Rojas and Diana, Castano
Frontiers in Immunology, ISSN 1664-3224, 2015, Volume 6
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14. Full Text Incomplete Normalization of Regulatory T-Cell Frequency in the Gut Mucosa of Colombian HIV-Infected Patients Receiving Long-Term Antiretroviral Treatment
by Rueda, Cesar M and Velilla, Paula A and Chougnet, Claire A and Rugeles, Maria T
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e71062
Introduction: To evaluate the effect of late initiation of HAART and poor immune reconstitution on the frequency of regulatory T-cells (Treg) in the peripheral... 
RESPONSES | SUPPRESS | THERAPY | LYMPHOID-TISSUE | MULTIDISCIPLINARY SCIENCES | IMMUNE ACTIVATION | COLLAGEN DEPOSITION | RESTORATION | HUMAN-IMMUNODEFICIENCY-VIRUS | MICROBIAL TRANSLOCATION | RECONSTITUTION | T-Lymphocytes, Regulatory - metabolism | Humans | Middle Aged | CTLA-4 Antigen - metabolism | Programmed Cell Death 1 Receptor - metabolism | Immunophenotyping | Male | Treatment Outcome | CD4 Lymphocyte Count | Case-Control Studies | Viral Load | T-Lymphocytes, Regulatory - immunology | Antiretroviral Therapy, Highly Active | HIV Infections - immunology | HIV-1 - immunology | Phenotype | Intestinal Mucosa - immunology | Adult | Female | HIV Infections - drug therapy | Cytokines - biosynthesis | Virus diseases | Highly active antiretroviral therapy | Antiviral agents | Medical research | Care and treatment | Analysis | Medicine, Experimental | HIV patients | T cells | HIV (Viruses) | HIV infection | Antiretroviral drugs | Immune response | PD-1 protein | Viremia | Mucosa | Immune reconstitution | T cell receptors | Lymphocytes T | Patients | Blood | Lipopolysaccharides | CD4 antigen | CTLA-4 protein | Immunology | Acquired immune deficiency syndrome--AIDS | Antiretroviral agents | Human immunodeficiency virus--HIV | CD38 antigen | Peripheral blood mononuclear cells | Histocompatibility antigen HLA | AIDS | HIV | Acquired immune deficiency syndrome | Human immunodeficiency virus
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15. Full Text Erratum to: Atorvastatin Modulates Regulatory T Cells and Attenuates Cerebral Damage in a Model of Transient Middle Cerebral Artery Occlusion in Rats (Journal of Neuroimmune Pharmacology, (2017), 12, 1, (152-162), 10.1007/s11481-016-9706-5)
by Rodríguez-Perea, Ana Lucía and Gutierrez-Vargas, Johanna and Cardona-Gómez, Gloria Patricia and Guarin, Carlos Julio Montoya and Rojas, Mauricio and Hernández, Paula Andrea Velilla
Journal of Neuroimmune Pharmacology, ISSN 1557-1890, 03/2017, Volume 12, Issue 1, p. 210
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16. Full Text Cytotoxic CD4+ T-cells during HIV infection: Targets or weapons?
by Sanchez-Martinez, Alexandra and Perdomo-Celis, Federico and Acevedo-Saenz, Liliana and Rugeles, Maria T and Velilla, Paula A
Journal of Clinical Virology, ISSN 1386-6532, 10/2019, Volume 119, pp. 17 - 23
Classically, CD4 T-cells have been referred as cytokine-producing cells and important players in immune responses by providing soluble factors that potentiate... 
CD4 | CD107a | Granzyme B | HIV | Cytotoxic | Perforin | EFFECTOR FUNCTIONS | INDUCTION | IDENTIFICATION | RESPONSES | REPLICATION | VIROLOGY | COMBINATION ANTIRETROVIRAL THERAPY | EXPRESSION | RECONSTITUTION | ANTIGEN
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17. Full Text Defective antigen-presenting cell function in human neonates
by Velilla, Paula A and Rugeles, Maria T and Chougnet, Claire A
Clinical Immunology, ISSN 1521-6616, 2006, Volume 121, Issue 3, pp. 251 - 259
Immaturity of the immune system has been suggested as an underlying factor for the high rate of morbidity and mortality from infections in newborns. Functional... 
Monocytes | Neonate | Dendritic cells | Costimulatory molecules | Cytokines | Antigen-presenting cells | Childhood | Regulatory T cells | Macrophages | Immune system | monocytes | antigen-presenting cells | childhood | EARLY-LIFE | INDOLEAMINE 2,3-DIOXYGENASE | MONONUCLEAR-CELLS | neonate | PERIPHERAL-BLOOD | HUMAN NEWBORNS | IMMUNOLOGY | TRYPTOPHAN CATABOLISM | regulatory T cells | macrophages | dendritic cells | IMMUNE-RESPONSES | costimulatory molecules | immune system | REGULATORY T-CELLS | cytokines | HUMAN CORD-BLOOD | Fetal Blood - immunology | Infant, Newborn - immunology | Antigen-Presenting Cells - cytology | Monocytes - cytology | Dendritic Cells - immunology | Humans | Dendritic Cells - pathology | Monocytes - immunology | Fetal Blood - cytology | Antigen-Presenting Cells - immunology | Antigen-Presenting Cells - pathology | Animals | Monocytes - pathology | T-Lymphocytes - immunology | Cell Differentiation | Dendritic Cells - cytology | Infants (Newborn) | Armored personnel carriers | Cell research | T cells | Immune System
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18. Full Text Different phenotypes of non‐classical monocytes associated with systemic inflammation, endothelial alteration and hepatic compromise in patients with dengue
by Naranjo‐Gómez, Juan S and Castillo, Jorge Andrés and Rojas, Mauricio and Restrepo, Berta N and Diaz, Francisco J and Velilla, Paula A and Castaño, Diana
Immunology, ISSN 0019-2805, 02/2019, Volume 156, Issue 2, pp. 147 - 163
Summary Although dengue can progress to severe stages, the exact causes of this phenomenon are unknown; however, the possibility of monocyte participation is... 
monocytes | monocyte subsets | severe dengue | non‐classical monocytes | dengue | non-classical monocytes | CELLS | POPULATION | ACTIVATION | VIRUS | SHOCK SYNDROME | IMMUNOLOGY | CD16(+) MONOCYTES | IN-VITRO | SOLUBLE CD14 | INFECTION | EXPRESSION | CC chemokine receptors | CD86 antigen | Leukocyte migration | Interleukin | Liver | CX3CR1 protein | Microparticles | Cell activation | CCR2 protein | Tumor necrosis factor-TNF | Phosphatidylserine | Vector-borne diseases | Phenotypes | CCR5 protein | CD11b antigen | Cytokines | Dengue | Patients | Endothelium | Monocytes | Tumor necrosis factor | Differentiation | Monocyte chemoattractant protein 1 | Cell migration | Tumors
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