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1. Full Text Evaluation of allergen-microarray–guided dietary intervention as treatment of eosinophilic esophagitis
by van Rhijn, Bram D., MD, PhD and Vlieg-Boerstra, Berber J., PhD, RD and Versteeg, Serge A., BSc and Akkerdaas, Jaap H., PhD and van Ree, Ronald, PhD and Terreehorst, Ingrid, MD, PhD and Sprikkelman, Aline B., MD, PhD and Verheij, Joanne, MD, PhD and Smout, Andreas J.P.M., MD, PhD and Bredenoord, Albert J., MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 4, pp. 1095 - 1097.e3
  [...]we compared sensitization patterns found using CRD with results of serum-IgE CAP testing and skin prick test (SPT). [...]to validate CRD results,... 
Allergy and Immunology | ADULTS | IMMUNOLOGY | ALLERGY | CHILDREN | Prospective Studies | Eosinophilic Esophagitis - diet therapy | Humans | Middle Aged | Adolescent | Allergens - chemistry | Eosinophilic Esophagitis - blood | Adult | Female | Male | Child | Protein Array Analysis - methods | Allergy | Allergens | Care and treatment | Allergic reaction | Analysis | Food allergies | Nuts | Diet | Endoscopy | Patients | Milk | Rice
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2. Full Text Aberrant p53 protein expression is associated with an increased risk of neoplastic progression in patients with Barrett's oesophagus
by Kastelein, Florine and Biermann, Katharina and Steyerberg, Ewout W and Verheij, Joanne and Kalisvaart, Marit and Looijenga, Leendert H J and Stoop, Hans A and Walter, Laurens and Kuipers, Ernst J and Spaander, Manon C W and Bruno, Marco J and ProBar-Study Grp and ProBar-study group and on behalf of the ProBar-study group
Gut, ISSN 0017-5749, 12/2013, Volume 62, Issue 12, pp. 1676 - 1683
Objective The value of surveillance for patients with Barrett's oesophagus (BO) is under discussion given the overall low incidence of neoplastic progression... 
POPULATION | Barrett's Carcinoma | ADENOCARCINOMA | OVEREXPRESSION | LOW-GRADE DYSPLASIA | Barrett's Metaplasia | METAPLASIA | COHORT | ACCUMULATION | Barrett's Oesophagus | GASTROENTEROLOGY & HEPATOLOGY | MALIGNANT PROGRESSION | DISEASE PROGRESSION | IMMUNOHISTOCHEMISTRY | Esophageal Neoplasms - etiology | Barrett Esophagus - metabolism | Barrett Esophagus - complications | Adenocarcinoma - pathology | Prospective Studies | Adenocarcinoma - etiology | Humans | Middle Aged | Risk Factors | Tumor Suppressor Protein p53 - metabolism | Esophagus - metabolism | Male | Precancerous Conditions - metabolism | Case-Control Studies | Esophageal Neoplasms - pathology | Esophagus - pathology | Adenocarcinoma - metabolism | Barrett Esophagus - pathology | Esophageal Neoplasms - metabolism | Female | Precancerous Conditions - pathology | Aged | Immunohistochemistry | Complications and side effects | Usage | Phosphoproteins | Barrett's esophagus | Influence | Development and progression | Risk factors | Tumors | Proteins | Studies | Surveillance | Biopsy | Biomarkers | Mutation | Endoscopy
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3. Full Text Activated tumor-infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer
by Peoza-Gonzalez, Alexander and Verhoef, Cornelis and Ijzermans, Jan N. M and Peppelenbosch, Maikel P and Kwekkeboom, Jaap and Verheij, Joanne and Janssen, Harry L. A and Sprengers, Dave
Hepatology (Baltimore, Md.), ISSN 0270-9139, 2013, Volume 57, Issue 1, pp. 183 - 194
The mechanisms that enable liver cancer to escape elimination by the immune system remain unclear, but their elucidation may provide novel therapeutic... 
HEPATOCELLULAR-CARCINOMA | CONTRIBUTE | VIRUS-INFECTION | DENDRITIC CELLS | MICROENVIRONMENT | COLORECTAL-CANCER | TOLERANCE | RECEPTOR | LIGAND | SUPPRESSION | GASTROENTEROLOGY & HEPATOLOGY | Cell Proliferation | Lymphocyte Activation | Humans | Middle Aged | Glucocorticoid-Induced TNFR-Related Protein - metabolism | Liver Neoplasms - drug therapy | Liver Neoplasms - immunology | Male | Tumor Necrosis Factors - therapeutic use | Carcinoma, Hepatocellular - drug therapy | Immunotherapy | Female | Aged | Carcinoma, Hepatocellular - immunology | Inducible T-Cell Co-Stimulator Protein - metabolism | Colorectal Neoplasms - pathology | Liver Neoplasms - secondary | T-Lymphocytes, Regulatory - physiology | Liver cancer | Medical research | Liver | Cancer | Tumors
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4. Full Text Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: a randomized, double-blind, placebo-controlled trial
by Visser, Maartje E and Wagener, Gilbert and Baker, Brenda F and Geary, Richard S and Donovan, Joanne M and Beuers, Ulrich H. W and Nederveen, Aart J and Verheij, Joanne and Trip, Mieke D and Basart, Dick C. G and Kastelein, John J. P and Stroes, Erik S. G
European heart journal, ISSN 0195-668X, 2012, Volume 33, Issue 9, pp. 1142 - 1149
A randomized, double-blind, placebo-controlled study was conducted to investigate the safety and efficacy of mipomersen, an apolipoprotein B-100 (apoB)... 
Antisense oligonucleotides | Lipoproteins | Hepatic steatosis | Hypercholesterolaemia | Statin intolerance | FAMILIAL HYPERCHOLESTEROLEMIA | CARDIAC & CARDIOVASCULAR SYSTEMS | FATTY LIVER-DISEASE | 20 MG | LDL CHOLESTEROL | HEART-DISEASE | MAGNETIC-RESONANCE-SPECTROSCOPY | ANTISENSE INHIBITOR | CORONARY ATHEROSCLEROSIS | INSULIN-RESISTANCE | Double-Blind Method | Oligonucleotides - therapeutic use | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Risk Factors | Male | Treatment Outcome | Cardiovascular Diseases - enzymology | Hypercholesterolemia - drug therapy | Anticholesteremic Agents - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Apolipoprotein B-100 - antagonists & inhibitors | Hypercholesterolemia - enzymology | Cholesterol, LDL - metabolism | Adult | Female | Aged | Alanine Transaminase - metabolism | Clinical Research
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5. Full Text Immunoglobulin G4(+) B-cell receptor clones distinguish immunoglobulin G 4-related disease from primary sclerosing cholangitis and biliary/pancreatic malignancies
by Doorenspleet, Marieke E and Hubers, Lowiek M and Culver, Emma L and Maillette de Buy Wenniger, Lucas J and Klarenbeek, Paul L and Chapman, Roger W and Baas, Frank and van de Graaf, Stan F and Verheij, Joanne and van Gulik, Thomas M and Barnes, Eleanor and Beuers, Ulrich and de Vries, Niek
Hepatology (Baltimore, Md.), ISSN 0270-9139, 2016, Volume 64, Issue 2, pp. 501 - 507
Immunoglobulin G4 (IgG4)-related disease (IgG4-RD) of the biliary tree and pancreas is difficult to distinguish from sclerosing cholangitis and... 
Diagnosis, Differential | Prospective Studies | Immunoglobulin G - blood | Humans | Middle Aged | Aged, 80 and over | Bile Duct Diseases - diagnosis | Female | Male | Aged | Bile Duct Diseases - immunology | Case-Control Studies | Immunoglobulins | Liver | Autoimmune, Cholestatic and Biliary Disease
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6. Full Text Immunoglobulin G4+ clones identified by next-generation sequencing dominate the B cell receptor repertoire in immunoglobulin G4 associated cholangitis
by Maillette de Buy Wenniger, Lucas J and Doorenspleet, Marieke E and Klarenbeek, Paul L and Verheij, Joanne and Baas, Frank and Elferink, Ronald P. Oude and Tak, Paul P and de Vries, Niek and Beuers, Ulrich
Hepatology (Baltimore, Md.), ISSN 0270-9139, 2013, Volume 57, Issue 6, pp. 2390 - 2398
Immunoglobulin G4 (IgG4)-associated cholangitis (IAC) is a manifestation of the recently discovered idiopathic IgG4-related disease. The majority of patients... 
G4-ASSOCIATED CHOLANGITIS | SCLEROSING CHOLANGITIS | GASTROENTEROLOGY & HEPATOLOGY | AUTOIMMUNE PANCREATITIS | SERUM IGG4 | Duodenum - immunology | Prospective Studies | Humans | Immunoglobulin G - chemistry | Middle Aged | Immunoglobulin Heavy Chains - chemistry | Male | Cholangitis - immunology | Cholangitis - blood | Case-Control Studies | Receptors, Antigen, B-Cell - chemistry | Adult | Female | Aged | Hepatology | Immunology | Immune system
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7. Full Text Comparing 3 guidelines on the management of surgically removed pancreatic cysts with regard to pathological outcome
by Lekkerkerker, Selma J., MD and Besselink, Marc G., MD, PhD and Busch, Olivier R., MD, PhD and Verheij, Joanne, MD, PhD and Engelbrecht, Marc R., MD, PhD and Rauws, Erik A., MD, PhD and Fockens, Paul, MD, PhD and van Hooft, Jeanin E., MD, PhD, MBA
Gastrointestinal Endoscopy, ISSN 0016-5107, 2017, Volume 85, Issue 5, pp. 1025 - 1031
Background and Aims Currently, 3 guidelines are available for the management of pancreatic cysts. These guidelines vary in their indication for resection of... 
Gastroenterology and Hepatology | PAPILLARY MUCINOUS NEOPLASMS | DIAGNOSIS | MALIGNANCY | PREVALENCE | GASTROENTEROLOGY & HEPATOLOGY | LESIONS | INTERNATIONAL CONSENSUS GUIDELINES | Neuroendocrine Tumors - pathology | Neoplasms, Cystic, Mucinous, and Serous - surgery | Neoplasms, Cystic, Mucinous, and Serous - pathology | Risk Assessment | Humans | Middle Aged | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - surgery | Male | Tumor Burden | Carcinoma, Pancreatic Ductal - pathology | Carcinoma, Pancreatic Ductal - surgery | Pancreaticoduodenectomy - methods | Pancreatic Cyst - pathology | Pancreatic Cyst - surgery | Adult | Female | Neuroendocrine Tumors - surgery | Aged | Retrospective Studies | Pancreatectomy - methods | Practice Guidelines as Topic | Cysts | Medical colleges
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8. Histological Response to Fluticasone Propionate in Patients with Eosinophilic Esophagitis is Associated with Improved Functional Esophageal Mucosal Integrity
by Van Rhijn, Bram D and Verheij, Joanne and Van Den Bergh Weerman, Marius A and Verseijden, Caroline and Van Den Wijngaard, René M. J. G. J and De Jonge, Wouter J and Smout, Andreas J. P. M and Bredenoord, Albert J
American Journal of Gastroenterology, ISSN 0002-9270, 09/2015, Volume 110, Issue 9, pp. 1289 - 1297
OBJECTIVES: The esophageal mucosal integrity is impaired in patients with eosinophilic esophagitis (EoE). We aimed to evaluate the effect of fluticasone... 
DESMOGLEIN | MULTIPLE ALLERGIES | GASTROESOPHAGEAL-REFLUX DISEASE | DERMATITIS | FILAGGRIN | ADULTS | VALIDATION | BUDESONIDE | SKIN | GASTROENTEROLOGY & HEPATOLOGY | CHILDREN | Intestinal Mucosa - metabolism | Intestinal Mucosa - physiopathology | Prospective Studies | Eosinophils - drug effects | Follow-Up Studies | Humans | Middle Aged | Eosinophilic Esophagitis - pathology | Male | Recovery of Function | Esophagoscopy | RNA - genetics | Dose-Response Relationship, Drug | Eosinophilic Esophagitis - physiopathology | Adult | Anti-Inflammatory Agents - administration & dosage | Female | Eosinophils - pathology | Leukocyte Count | Cytokines - genetics | Real-Time Polymerase Chain Reaction | Intestinal Mucosa - ultrastructure | Gene Expression Regulation | Treatment Outcome | Electric Impedance | Deglutition - physiology | Microscopy, Electron | Biopsy | Fluticasone - administration & dosage | Eosinophilic Esophagitis - drug therapy | Cytokines - biosynthesis
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9. Full Text Anatomical, histomorphological and molecular classification of cholangiocarcinoma
by Kendall, Timothy and Verheij, Joanne and Gaudio, Eugenio and Evert, Matthias and Guido, Maria and Goeppert, Benjamin and Carpino, Guido
Liver International, ISSN 1478-3223, 05/2019, Volume 39, Issue S1, pp. 7 - 18
Cholangiocarcinoma constitutes a heterogeneous group of malignancies that can emerge at any point of the biliary tree. Cholangiocarcinoma is classified into... 
diagnosis | preneoplastic lesion | molecular profile | cholangiocarcinoma | INTRAHEPATIC CHOLANGIOCARCINOMA | BILE-DUCT | CHOLANGIOLOCELLULAR CARCINOMA | PAPILLARY MUCINOUS NEOPLASM | IN-SITU HYBRIDIZATION | BILIARY-TRACT | GROWTH-FACTOR RECEPTOR | HEPATOCELLULAR-CARCINOMA | GASTROENTEROLOGY & HEPATOLOGY | INTRADUCTAL TUBULOPAPILLARY NEOPLASMS | PRIMARY SCLEROSING CHOLANGITIS | Fibroblast growth factors | Tumor proteins | Health aspects | Analysis | Fibroblast growth factor | p53 Protein | Carcinogenesis | Neoplasms | Subgroups | Bile duct | Carcinogens | Mucin | Surgery | Tumor suppressor genes | Mutation | Diagnosis | Lesions | Isocitrate dehydrogenase | Growth factors | Cholangiocarcinoma | Fibroblast growth factor receptor 2 | Tumors | Bile
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10. Full Text Non-invasive evaluation of liver fibrosis: a comparison of ultrasound-based transient elastography and MR elastography in patients with viral hepatitis B and C
by Bohte, Anneloes E and de Niet, Annikki and Jansen, Louis and Bipat, Shana and Nederveen, Aart J and Verheij, Joanne and Terpstra, Valeska and Sinkus, Ralph and van Nieuwkerk, Karin M. J and de Knegt, Rob J and Baak, Bert C and Jansen, Peter L. M and Reesink, Henk W and Stoker, Jaap
European radiology, ISSN 0938-7994, 2014, Volume 24, Issue 3, pp. 638 - 648
To compare the diagnostic accuracy of TE and MRE and establish cutoff levels and diagnostic strategies for both techniques, enabling selection of patients for... 
Medicine & Public Health | Diagnostic Radiology | Elasticity imaging techniques | Sensitivity and specificity | Internal Medicine | Interventional Radiology | Imaging / Radiology | Hepatitis C | Ultrasound | Neuroradiology | Hepatitis B | PERFORMANCE | STIFFNESS MEASUREMENT | MAGNETIC-RESONANCE ELASTOGRAPHY | BIOPSIES | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | REPRODUCIBILITY | ACCURACY | Liver Cirrhosis - etiology | Hepatitis C, Chronic - pathology | Prospective Studies | Area Under Curve | Hepatitis C, Chronic - diagnostic imaging | Humans | Middle Aged | Magnetic Resonance Imaging - methods | Male | Hepatitis C, Chronic - complications | Hepatitis B, Chronic - diagnostic imaging | Elasticity Imaging Techniques - methods | Young Adult | Hepatitis B, Chronic - complications | Liver Cirrhosis - diagnostic imaging | Biopsy | Sensitivity and Specificity | Liver Cirrhosis - pathology | Adult | Female | ROC Curve | Hepatitis B, Chronic - pathology | Care and treatment | Comparative analysis | Liver | Fibrosis
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11. Full Text A casein hydrolysate based formulation attenuates obesity and associated non-alcoholic fatty liver disease and atherosclerosis in LDLr-/-.Leiden mice
by Schoemaker, Marieke H and Kleemann, Robert and Morrison, Martine C and Verheij, Joanne and Salic, Kanita and van Tol, Eric A. F and Kooistra, Teake and Wielinga, Peter Y
PLoS ONE, ISSN 1932-6203, 2017, Volume 12, Issue 7, p. e0180648
Obesity frequently associates with the development of non-alcoholic fatty liver disease (NAFLD) and atherosclerosis. Chronic inflammation in white adipose... 
SUPPLEMENTATION | WHITE ADIPOSE-TISSUE | BODY-WEIGHT | ACIDS | INSULIN-RESISTANCE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | STEATOHEPATITIS | DIET-INDUCED OBESITY | DEVELOPMENTAL ORIGINS | INFANT FORMULAS | Receptors, LDL - genetics | Adiposity - drug effects | Male | Caseins - administration & dosage | Animals | Diet, High-Fat | Obesity - prevention & control | Non-alcoholic Fatty Liver Disease - prevention & control | Mice | Receptors, LDL - physiology | Weight Gain | Caseins - pharmacology | Atherosclerosis - prevention & control | Medicine, Experimental | Obesity | Medical research | Models | Casein | Health aspects | Adipose tissue | Peptides | Liver | Body weight | Colony-forming cells | Arachidonic acid | Metabolic syndrome | Docosahexaenoic acid | Tissues | Low fat | Risk factors | High fat diet | Proteins | Fatty liver | Rodents | Risk assessment | Atherosclerosis | Attenuation | Lipoprotein (low density) receptors | Amyloid | Lactobacillus rhamnosus | Carbohydrates | Liver diseases | Nutrient deficiency | Ingredients | Triglycerides | Inflammation | Risk analysis | Insulin | Fatty acids | Cholesterol | Steatosis | Studies | Nutrition research | Probiotics | Diet | Food intake | Arteriosclerosis | Leptin | Collagen | Low fat diet | Weight reduction | Endocrinology
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12. IgG4-Associated Cholangitis in Patients Resected for Presumed Perihilar Cholangiocarcinoma: A 30-Year Tertiary Care Experience
by Roos, Eva and Hubers, Lowiek M and Coelen, Robert J. S and Doorenspleet, Marieke E and De Vries, Niek and Verheij, Joanne and Beuers, Ulrich and Van Gulik, Thomas M
American Journal of Gastroenterology, ISSN 0002-9270, 05/2018, Volume 113, Issue 5, pp. 765 - 772
Background: Distinguishing perihilar cholangiocarcinoma (PHC) from benign forms of sclerosing cholangitis affecting the hilar bile ducts is challenging, since... 
SURGICAL COMPLICATIONS | DIAGNOSIS | SCLEROSING CHOLANGITIS | PERORAL CHOLANGIOSCOPY | IMMUNOGLOBULIN G4-ASSOCIATED CHOLANGITIS | BILIARY STRICTURES | BIOPSY | G4-RELATED DISEASE | CLASSIFICATION | GASTROENTEROLOGY & HEPATOLOGY | UTILITY | Recurrence | Liver - pathology | Follow-Up Studies | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Netherlands - epidemiology | Klatskin Tumor - diagnosis | Male | Incidence | Tertiary Healthcare - statistics & numerical data | Immunoglobulin G - immunology | Klatskin Tumor - pathology | Adult | Female | Retrospective Studies | Liver - surgery | Diagnostic Errors - statistics & numerical data | Bile Duct Neoplasms - surgery | Diagnosis, Differential | Klatskin Tumor - mortality | Survival Rate | Bile Ducts - surgery | Bile Duct Neoplasms - diagnosis | Cholangitis, Sclerosing - epidemiology | Cholangitis, Sclerosing - therapy | Cholangitis, Sclerosing - immunology | Bile Duct Neoplasms - mortality | Aged | Cholangitis, Sclerosing - diagnosis | Bile Duct Neoplasms - pathology | Klatskin Tumor - surgery | Bile Ducts - pathology
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13. Full Text International Validation of the Eighth Edition of the American Joint Committee on Cancer (AJCC) TNM Staging System in Patients with Resected Pancreatic Cancer
by van Roessel, Stijn and Kasumova, Gyulnara G and Verheij, Joanne and Najarian, Robert M and Maggino, Laura and de Pastena, Matteo and Malleo, Giuseppe and Marchegiani, Giovanni and Salvia, Roberto and Ng, Sing Chau and de Geus, Susanna W and Lof, Sanne and Giovinazzo, Francesco and van Dam, Jacob L and Kent, Tara S and Busch, Olivier R and van Eijck, Casper H and Koerkamp, Bas Groot and Abu Hilal, Mohammed and Bassi, Claudio and Tseng, Jennifer F and Besselink, Marc G
JAMA surgery, ISSN 2168-6254, 2018, Volume 153, Issue 12, p. e183617
Importance: The recently released eighth edition of the American Joint Committee on Cancer TNM staging system for pancreatic cancer seeks to improve prognostic... 
PANCREATICODUODENECTOMY | SURGERY | CLASSIFICATION | LYMPH-NODE RATIO | Online First | Online Only | Research | Original Investigation
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