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1. Full Text Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study
by Howard, James F and Utsugisawa, Kimiaki and Benatar, Michael and Murai, Hiroyuki and Barohn, Richard J and Illa, Isabel and Jacob, Saiju and Vissing, John and Burns, Ted M and Kissel, John T and Muppidi, Srikanth and Nowak, Richard J and O'Brien, Fanny and Wang, Jing-Jing and Mantegazza, Renato and Mazia, Claudio Gabriel and Wilken, Miguel and Ortea, Carolina and Saba, Juliet and Rugiero, Marcelo and Bettini, Mariela and Vidal, Gonzalo and Vidal, Nuria and Garcia, Rebekah and Garcia, Sonia and Garcia, Alejandra Dalila and Lamont, Phillipa and Leong, Wai-Kuen and Boterhoven, Heidi and Fyfe, Beverly and Roberts, Leslie and Jasinarachchi, Mahi and Willlems, Natasha and Wanschitz, Julia and Löscher, Wolfgang and De Bleecker, Jan and Van den Abeele, Guy and de Koning, Kathy and De Mey, Katrien and Mercelis, Rudy and Wagemaekers, Linda and Mahieu, Delphine and Van Damme, Philip and Smetcoren, Charlotte and Stevens, Olivier and Verjans, Sarah and D'Hondt, Ann and Tilkin, Petra and Alves de Siqueira Carvalho, Alzira and Hasan, Rosa and Dias Brockhausen, Igor and Feder, David and Ambrosio, Daniel and Melo, Ana Paula and Rocha, Rosana and Rosa, Bruno and Veiga, Thabata and Augusto da Silva, Luiz and Gonçalves Geraldo, Jordana and da Penha Morita Ananias, Maria and Nogueira Coelho, Erica and Paiva, Gabriel and Pozo, Marina and Prando, Natalia and Dada Martineli Torres, Debora and Fernanda Butinhao, Cristiani and Coelho, Erica and Renata Cubas Volpe, Luciana and Duran, Gustavo and Gomes da Silva, Tamires Cristina and Otavio Maia Gonçalves, Luiz and Pazetto, Lucas Eduardo and Souza Duca, Luciana and Suriane Fialho, Tomás Augusto and Gheller Friedrich, Maurício André and Guerreiro, Alexandre and Mohr, Henrique and Pereira Martins, Maurer and da Cruz Pacheco, Daiane and Macagnan, Ana Paula and de Cassia Santos, Aline and Bulle Oliveira, Acary Souza and Amaral de Andrade, Ana Carolina and Annes, Marcelo and Cavalcante Lino, Valeria and Pinto, Wladimir and Miranda, Carolina and Carrara, Fernanda and Souza, Iandra and Genge, Angela and Massie, Rami and Campbell, Natasha and Bril, Vera and Katzberg, Hans and Soltani, Mehran and Ng, Eduardo and Siddiqi, Zaeem and Phan, Celile and Blackmore, Derrick and Vohanka, Stanislav and ... and REGAIN Study Grp and REGAIN Study Group
The Lancet Neurology, ISSN 1474-4422, 12/2017, Volume 16, Issue 12, pp. 976 - 986
Complement is likely to have a role in refractory generalised myasthenia gravis, but no approved therapies specifically target this system. Results from a... 
TRIAL | ENDPLATE | C3 | LOCALIZATION | COMPLEMENT INHIBITOR ECULIZUMAB | C9 | DAILY LIVING PROFILE | PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA | ACETYLCHOLINE-RECEPTOR | END-PLATE | CLINICAL NEUROLOGY | Severity of Illness Index | Antibodies, Monoclonal, Humanized - adverse effects | Double-Blind Method | Myasthenia Gravis - blood | Outcome Assessment (Health Care) | Autoantibodies - blood | Humans | Middle Aged | Male | Antibodies, Monoclonal, Humanized - administration & dosage | Myasthenia Gravis - physiopathology | Antibodies, Monoclonal, Humanized - pharmacology | Adult | Female | Receptors, Cholinergic - immunology | Aged | Myasthenia Gravis - drug therapy | Drug Resistance | Studies | Neurology | Immunoglobulins | Activities of daily living | Myasthenia gravis | Transplants & implants | Neuromuscular junctions | Myasthenia | Patients
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2. Full Text Detection of circovirus in foxes with meningoencephalitis, United Kingdom, 2009–2013
by Bexton, Steve and Wiersma, Lidewij and Getu, Sarah and Run, Peter and Verjans, George and Schipper, Debby and Schapendonk, Claudia and Bodewes, Rogier and Oloyd, Lucy and Haagmans, Bart and Koopmans, Marion and Smits, Saskia
Emerging Infectious Diseases (Print), ISSN 1080-6040, 01/2015, Volume 21, Issue 7, pp. 1205 - 1208
textabstractA fox circovirus was identified in serum samples from foxes with unexplained neurologic signs by using viral metagenomics. Fox circovirus nucleic... 
INFECTIOUS DISEASES | MULTIPLE | IMMUNOLOGY | Circoviridae Infections - veterinary | Foxes - virology | Meningoencephalitis - diagnosis | Meningoencephalitis - veterinary | Circoviridae Infections - diagnosis | Circoviridae Infections - virology | Brain - virology | Male | United Kingdom | Circovirus - isolation & purification | Molecular Diagnostic Techniques | Animals | Meningoencephalitis - virology | Circovirus - genetics | Brain - pathology | Female | Real-Time Polymerase Chain Reaction | viruses | cyclovirus | circovirus | Detection of Circovirus in Foxes with Meningoencephalitis, United Kingdom | Dispatch | foxes | brain | random amplification | meningoencephalitis | neurologic disease | encephalitis | cerebrospinal fluid | serum
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3. Full Text High seroprevalence of human herpesviruses in HIV-infected individuals attending primary healthcare facilities in rural South Africa
by Schaftenaar, Willem and Verjans, George and Getu, Sarah and McIntyre, James and Struthers, Helen and Osterhaus, Albert and Peters, Remco
PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, p. e99243
textabstractSeroprevalence data of human herpesviruses (HHVs) are limited for sub-Saharan Africa. These are important to provide an indication of potential... 
TRANSMISSION | SIMPLEX-VIRUS TYPE-2 | WEST-AFRICA | SUB-SAHARAN AFRICA | VARICELLA | REACTIVATION | MULTIDISCIPLINARY SCIENCES | ZOSTER | ANTIRETROVIRAL THERAPY | PREVALENCE | CYTOMEGALOVIRUS | HIV Infections - blood | Rural Population - statistics & numerical data | Demography | Simplexvirus - physiology | Immunoglobulin G - blood | Primary Health Care - statistics & numerical data | HIV Infections - epidemiology | HIV Infections - virology | Humans | Risk Factors | South Africa - epidemiology | Male | Seroepidemiologic Studies | HIV Infections - complications | Adult | Female | Virus diseases | Highly active antiretroviral therapy | Antiviral agents | Primary health care | Immunoglobulin G | Cross infection | Herpesviruses | Nosocomial infections | HIV (Viruses) | Health aspects | HIV infection | Health care | Drinking water | Cytomegalovirus | Laboratories | Chicken pox | Herpes simplex | Viruses | Infections | Multivariate analysis | Minority & ethnic groups | Antiretroviral therapy | CD4 antigen | Studies | Disease transmission | Antiretroviral agents | Human immunodeficiency virus--HIV | Herpes viruses | Varicella | Population | Standard deviation | Children | Age | HIV | Human immunodeficiency virus
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4. Full Text T-Cell Infiltration Correlates with CXCL10 Expression in Ganglia of Cynomolgus Macaques with Reactivated Simian Varicella Virus
by Werner J. D. Ouwendijk and Allison Abendroth and Vicki Traina-Dorge and Sarah Getu and Megan Steain and Mary Wellish and Arno C. Andeweg and Albert D. M. E. Osterhaus and Don Gilden and Georges M. G. M. Verjans and Ravi Mahalingam
Journal of Virology, ISSN 0022-538X, 03/2013, Volume 87, Issue 5, pp. 2979 - 2982
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
IMMUNE-RESPONSE | HERPES-SIMPLEX-VIRUS | VIROLOGY | ZOSTER | HUMAN TRIGEMINAL GANGLIA | INFECTION | MONKEYS | Ganglia - metabolism | Ganglia - virology | Open Reading Frames | Macaca fascicularis | RNA, Messenger - metabolism | Viral Load | CD4-Positive T-Lymphocytes - immunology | Varicellovirus - immunology | CD8-Positive T-Lymphocytes - metabolism | Varicellovirus - physiology | Herpesviridae Infections - genetics | Virus Activation | Neurons - virology | Varicellovirus - genetics | RNA, Messenger - genetics | Neurons - immunology | RNA, Antisense - biosynthesis | Herpesviridae Infections - virology | Varicellovirus - metabolism | Animals | CD8-Positive T-Lymphocytes - immunology | DNA, Viral - genetics | Chemokine CXCL10 - metabolism | Ganglia - immunology | Herpesviridae Infections - immunology | Virus Latency - genetics | Cellular Response to Infection
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5. Full Text Eculizumab improves fatigue in refractory generalized myasthenia gravis
by Andersen, Henning and Mantegazza, Renato and Wang, Jing Jing and O’Brien, Fanny and Patra, Kaushik and Howard Jr, James F and REGAIN Study Grp and REGAIN Study Group and The REGAIN Study Group
Quality of Life Research, ISSN 0962-9343, 8/2019, Volume 28, Issue 8, pp. 2247 - 2254
To evaluate the effect of eculizumab on perceived fatigue in patients with anti-acetylcholine receptor antibody-positive, refractory, generalized myasthenia... 
Public Health | Terminal complement inhibition | Myasthenia gravis | Medicine & Public Health | Quality of Life Research | Eculizumab | Fatigue | Complement | Sociology, general | Neuro-QOL Fatigue | Quality of life | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | HEALTH CARE SCIENCES & SERVICES | HEALTH POLICY & SERVICES | QUALITY-OF-LIFE | Analysis | Brief Communication
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6. Full Text T-Cell Tropism of Simian Varicella Virus during Primary Infection
by Ouwendijk, Werner and Mahalingam, Ravi and Swart, Rik and Haagmans, Bart and Amerongen, Geert and Getu, Sarah and Gilden, Don and Osterhaus, Albert and Verjans, George
PL o S Pathogens (Online), ISSN 1553-7366, 05/2013, Volume 9, Issue 5, p. e1003368
textabstractVaricella-zoster virus (VZV) causes varicella, establishes a life-long latent infection of ganglia and reactivates to cause herpes zoster. The cell... 
DENDRITIC CELLS | AFRICAN-GREEN MONKEYS | DORSAL-ROOT GANGLIA | MICROBIOLOGY | VIRAL REPLICATION | SATELLITE GLIAL-CELLS | ZOSTER-VIRUS | VIROLOGY | IN-VIVO | HERPES-SIMPLEX | HUMAN TRIGEMINAL GANGLIA | SENSORY GANGLIA | PARASITOLOGY | Immunohistochemistry | Cercopithecus aethiops | Male | Chickenpox - pathology | Herpesvirus 3, Human | Chickenpox - immunology | T-Lymphocytes - virology | Animals | Flow Cytometry | Chickenpox - virology | Female | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Tropisms | Physiological aspects | Host-parasite relationships | Research | Varicella-zoster virus | T cells | Health aspects | Proteins | Pathology | Infections | Lymphocytes | Rodents
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7. Full Text Norovirus infection in harbor porpoises
by de Graaf, Miranda and Bodewes, Rogier and van Elk, Cornelis E and van de Bildt, Marco and Getu, Sarah and Aron, Georgina I and Verjans, Georges M. G. M and Osterhaus, Albert D. M. E and van den Brand, Judith M. A and Kuiken, Thijs and Koopmans, Marion P. G
Emerging Infectious Diseases, ISSN 1080-6040, 01/2017, Volume 23, Issue 1, pp. 87 - 91
A norovirus was detected in harbor porpoises, a previously unknown host for norovirus. This norovirus had low similarity to any known norovirus. Viral RNA was... 
INFECTIOUS DISEASES | IMMUNOLOGY | Genome, Viral | Caliciviridae Infections - virology | Intestines - pathology | RNA Replicase - genetics | Viral Proteins - genetics | Caliciviridae Infections - veterinary | Phylogeny | Animals | Phocoena - virology | North Sea - epidemiology | Norovirus - classification | Intestines - virology | Caliciviridae Infections - epidemiology | Norovirus - genetics | RNA | Gastroenteritis | Genomics | Sea lions | B cells | Harbors | Health aspects | Porpoises | viruses | Norovirus | intestine | genotype GI | porpoise | marine mammals | Phocoena phocoena | Dispatch | zoonoses | Norovirus Infection in Harbor Porpoises
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8. Full Text Asymptomatic middle east respiratory syndrome coronavirus infection in rabbits
by Haagmans, Bart and Brand, Judith and Provacia, Lisette and Stalin Raj, V and Stittelaar, Koert and Getu, Sarah and Waal, Leon and Bestebroer, Theo and Amerongen, Geert and Verjans, George and Fouchier, Ron and Smits, Saskia and Kuiken, Thijs and Osterhaus, Albert
Journal of Virology, ISSN 0022-538X, 01/2015, Volume 89, Issue 11, pp. 6131 - 6135
textabstractThe ability of Middle East respiratory syndrome coronavirus (MERS-CoV) to infect small animal species may be restricted given the fact that mice,... 
GENERATION | VIROLOGY | MOUSE MODEL | Rabbits | Cricetinae | Lung - pathology | Virus Shedding | Asymptomatic Diseases | Respiratory System - virology | Lung - virology | Animals | Coronavirus Infections - virology | Coronavirus Infections - pathology | Middle East Respiratory Syndrome Coronavirus - isolation & purification | Female | Mice | Middle East Respiratory Syndrome Coronavirus - growth & development | Disease Models, Animal
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9. Full Text Central nervous system disease and genital disease in harbor porpoises (Phocoena phocoena) are associated with different herpesviruses
by Elk, C.E and Bildt, Marco and Run, Peter and De Jong, A and Getu, Sarah and Verjans, George and Osterhaus, Albert and Kuiken, Thijs
Veterinary Research, ISSN 0928-4249, 02/2016, Volume 47, Issue 1, p. 28
textabstractHerpesvirus infection causes disease of variable severity in many species, including cetaceans. However, little is known about herpesvirus... 
BOTTLE-NOSED DOLPHINS | INFECTIONS | CETACEANS | CANARY-ISLANDS | ALPHAHERPESVIRUSES | VETERINARY SCIENCES | TURSIOPS-TRUNCATUS | POSTMORTEM FINDINGS | IDENTIFICATION | TYPE-1 | LESIONS | Phocoena | Netherlands - epidemiology | Herpesviridae Infections - veterinary | Molecular Sequence Data | Male | Genital Diseases, Male - epidemiology | Phylogeny | Viral Proteins - metabolism | Central Nervous System Diseases - virology | Genital Diseases, Male - veterinary | Herpesviridae - genetics | Female | Herpesviridae - classification | Central Nervous System Diseases - veterinary | Genital Diseases, Female - virology | Genital Diseases, Male - virology | Belgium - epidemiology | Central Nervous System Diseases - epidemiology | Viral Proteins - genetics | Herpesviridae Infections - virology | Genital Diseases, Female - epidemiology | Genital Diseases, Female - veterinary | Germany - epidemiology | Animals | Herpesviridae - physiology | Sequence Analysis, DNA - veterinary | Herpesviridae Infections - epidemiology | Veterinary medicine | Medical research | Life Sciences
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10. Full Text Neurosyphilis mimicking young-onset Alzheimer’s disease: a case report explaining the pitfalls of FDG-PET
by Verjans, Sarah and Van Laere, Koen and Vandenberghe, Rik
Acta Neurologica Belgica, ISSN 0300-9009, 6/2016, Volume 116, Issue 2, pp. 207 - 210
Neurology | Neurosciences | Biomedicine | Medicine/Public Health, general | Neuroradiology
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11. Full Text Clinical and corneal microbial profile of infectious keratitis in a high HIV prevalence setting in rural South Africa
by Schaftenaar, Willem and Peters, Remco and Baarsma, Seerp and Meenken, Christina and Khosa, N.S and Getu, Sarah and McIntyre, James and Osterhaus, Albert and Verjans, George
European Journal of Clinical Microbiology & Infectious Diseases: an international journal on pathogenesis, diagnosis, epidemiology, therapy, and prevention of infectious diseases, ISSN 0934-9723, 09/2016, Volume 35, Issue 9, pp. 1403 - 1409
textabstractThe purpose of this investigation was to determine the clinical and corneal microbial profile of infectious keratitis in a high human... 
Medical Microbiology | Internal Medicine | Biomedicine | ETIOLOGY | INFECTIOUS DISEASES | VIRUS | DISEASE | ANTERIOR SEGMENT | MICROBIOLOGY | TANZANIA | Prevalence | Fungi - classification | HIV Infections - epidemiology | Humans | Middle Aged | DNA, Viral - isolation & purification | Fungi - isolation & purification | Keratoconjunctivitis, Infectious - epidemiology | Male | Young Adult | Rural Population | Aged, 80 and over | Bacteria - classification | Adult | Bacteriological Techniques | Female | Keratoconjunctivitis, Infectious - virology | Keratoconjunctivitis, Infectious - microbiology | Cornea - microbiology | Cornea - virology | Viruses - isolation & purification | Cross-Sectional Studies | South Africa - epidemiology | Viruses - classification | Bacteria - isolation & purification | Animals | Adolescent | HIV Infections - complications | Aged | DNA, Viral - genetics | Hospitals | Keratitis | Microbiology | Adenoviruses | Bacteria | Ophthalmology | HIV (Viruses) | Health aspects | HIV infection | Original
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