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Molecular Neurobiology, ISSN 0893-7648, 08/2019, pp. 1 - 15
A local renin-angiotensin system (RAS) exists in the retina and plays a critical role in retinal neurovascular function. The protective axis of RAS comprising... 
NF-κB protein | Reactive oxygen species | Hydrogen peroxide | Peptides | Retina | Inflammation | Gene expression | Neuronal-glial interactions | Lipopolysaccharides | Renin | Peptidyl-dipeptidase A | Angiotensin | Mice | Angiotensin II | Localization | Structure-function relationships | Index Medicus
Journal Article
by Li, QH and Xu, K and Du, T and Zhu, P and Verma, A
DIABETES, ISSN 0012-1797, 07/2018, Volume 67, Issue Supplement 1, p. 33
Purpose: Multitude of animal studies substantiate the beneficial effects of Ang-(1-7) in diabetes and associated complications. However, the biggest impediment... 
ENDOCRINOLOGY & METABOLISM | Diabetic retinopathy | Animal models | Kidneys | Diabetes mellitus | Oral administration | Retina | Glucose | Bioavailability | Insulin | Glucose tolerance | Probiotics | Glucose metabolism | Gliosis | Cell death | Collagen | Angiotensin | Kidney diseases | Capillaries | Fusion protein | ACE inhibitors | Apoptosis
Conference Proceeding
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 05/2014, Volume 55, Issue 6, pp. 3809 - 3818
Journal Article
Experimental Eye Research, ISSN 0014-4835, 10/2019, Volume 187, pp. 107770 - 107770
The renin-angiotensin system (RAS) plays a vital role in cardiovascular physiology and body homeostasis. In addition to circulating RAS, a local RAS exists in... 
Retina | Renin angiotensin system | C21 | Angiotensin II | AT2R | Index Medicus
Journal Article
Molecular Therapy, ISSN 1525-0016, 01/2012, Volume 20, Issue 1, pp. 28 - 36
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 08/2017, Volume 21, Issue 8, pp. 1555 - 1571
Elevated vascular endothelial growth factor ( VEGF ) and complement activation are implicated in the pathogenesis of different ocular diseases. The objective... 
autoimmune uveitis | age‐related macular degeneration | choroidal neovascularization | angiogenesis | AAV | vascular endothelial growth factor | gene therapy | ocular inflammation | complement | uveitis | age-related macular degeneration | MEDICINE, RESEARCH & EXPERIMENTAL | MODEL | CELL BIOLOGY | MEMBRANE ATTACK COMPLEX | INHIBITION | EPITHELIAL-CELLS | AFLIBERCEPT | VEGF TRAP-EYE | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Recombinant Fusion Proteins - immunology | Dependovirus - genetics | Retinitis - therapy | Immunoglobulin Fc Fragments - metabolism | Endotoxins | Choroidal Neovascularization - therapy | Green Fluorescent Proteins - genetics | Retina - immunology | Vascular Endothelial Growth Factor Receptor-2 - immunology | Vascular Endothelial Growth Factor A - genetics | Vascular Endothelial Growth Factor Receptor-2 - genetics | Retinitis - genetics | Retinitis - immunology | Choroidal Neovascularization - pathology | Vascular Endothelial Growth Factor Receptor-1 - immunology | Protein Domains | Choroid - pathology | Genes, Reporter | Vascular Endothelial Growth Factor Receptor-1 - genetics | Green Fluorescent Proteins - metabolism | Retinitis - pathology | Uveitis - therapy | Gene Expression | Dependovirus - metabolism | Genetic Vectors - chemistry | Choroidal Neovascularization - immunology | Mice, Inbred C57BL | Genetic Vectors - metabolism | Vascular Endothelial Growth Factor A - immunology | Animals | Uveitis - immunology | Autoimmune Diseases | Recombinant Fusion Proteins - genetics | Choroid - immunology | Mice | Uveitis - genetics | Choroidal Neovascularization - genetics | Immunoglobulin Fc Fragments - genetics | Retina - pathology | Uveitis - chemically induced | Genetic Therapy - methods | Macular degeneration | Proteins | Analysis | Eye diseases | Inflammation | Neovascularization | Vascular endothelial growth factor | Endothelium | Animal models | Pathogenesis | Secretion | Retina | Activation | Complement | Vascularization | Complement activation | Inhibitors | Rodents | Structural damage | Uveitis | Eye (anatomy) | Infiltration | Gene therapy | Experimental autoimmune uveoretinitis | Recombinant | Index Medicus | Original
Journal Article
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 5/2011, Volume 203, Issue 10, pp. 1369 - 1377
Journal Article
Diabetes, ISSN 0012-1797, 12/2012, Volume 61, Issue 12, pp. 3270 - 3279
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, pp. e100954 - e100954
textabstractDysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabetic retinopathy (DR). Prorenin, the precursor of renin is... 
PLASMA PRORENIN | IN-VITRO | NONPROTEOLYTIC ACTIVATION | BINDING-KINETICS | HUMAN (PRO)RENIN RECEPTOR | MULTIDISCIPLINARY SCIENCES | SMOOTH-MUSCLE-CELLS | ANGIOTENSIN-II | HANDLE-REGION PEPTIDE | (MREN-2)27 RAT | MULLER CELLS | Blood Pressure | Diabetic Retinopathy - drug therapy | Apoptosis - genetics | Fumarates - administration & dosage | Diabetic Retinopathy - pathology | Receptors, Cell Surface - antagonists & inhibitors | Retinal Ganglion Cells - metabolism | Gliosis - pathology | Renin - genetics | Inflammation Mediators - metabolism | Disease Models, Animal | Amides - pharmacology | Cytokines - metabolism | Gliosis - metabolism | Rats | Receptors, Cell Surface - metabolism | Mice, Transgenic | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Animals | Renin - antagonists & inhibitors | Fumarates - pharmacology | Oligopeptides - administration & dosage | Oligopeptides - pharmacology | Amides - administration & dosage | Diabetic retinopathy | Genetic engineering | Cytokines | Angiotensin | Drugs | Retinopathy | Peptides | Pathogenesis | Streptozocin | Transgenic | Retina | Smooth muscle | Kinases | Renin | Rodents | Inhibition | Capillaries | Angiotensin II | Hypertension | Internal medicine | Diabetes mellitus | Pharmacology | Inflammation | siRNA | Tumor necrosis factor-α | Medicine | Gliosis | Cell death | Photoreceptors | Diabetes | Metabolic disorders | Apoptosis | Index Medicus
Journal Article