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science & technology (21) 21
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humans (16) 16
genetics (13) 13
genetics & heredity (11) 11
genomes (11) 11
gene expression (9) 9
male (8) 8
dna methylation (7) 7
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exome (4) 4
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adolescent (3) 3
algorithms (3) 3
bias (3) 3
body-mass index (3) 3
cardiovascular-disease (3) 3
de-novo mutations (3) 3
deoxyribonucleic acid--dna (3) 3
dna sequencing (3) 3
empirical null distribution (3) 3
epigenome- and transcriptome-wide association studies (3) 3
genes (3) 3
genetic aspects (3) 3
genome-wide association (3) 3
gibbs sampler (3) 3
inflation (3) 3
methods (3) 3
models, genetic (3) 3
mutation (3) 3
nucleotide sequence (3) 3
obesity (3) 3
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research (3) 3
sequence analysis, dna - methods (3) 3
smoking (3) 3
technology (3) 3
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aged, 80 and over (2) 2
alleles (2) 2
alternative splicing (2) 2
analysis (2) 2
biobanking (2) 2
biochemistry, genetics and molecular biology (2) 2
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body mass index (2) 2
caars (2) 2
cell biology (2) 2
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chromosomes (2) 2
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dna methylation - genetics (2) 2
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ecology, evolution, behavior and systematics (2) 2
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gene-environment interaction (2) 2
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health (2) 2
heritability (2) 2
high-throughput nucleotide sequencing (2) 2
high-throughput nucleotide sequencing - methods (2) 2
high-throughput nucleotide sequencing - standards (2) 2
hne nutrition and health over the lifecourse (2) 2
hne voeding en gezondheid in de levenscyclus (2) 2
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1. Full Text Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing
by Anvar, S.Y and Allard, G and Tseng, E and Sheynkman, G.M and Klerk, E. de and Vermaat, M and Yin, R.H and Johansson, H.E and Ariyurek, Y and Dunnen, J.T. den and Turner, S.W and Hoen, P.A.C. 't
Genome biology, ISSN 1474-760X, 2018, Volume 19, Issue 1, pp. 46 - 46
Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Alternative splicing | Post-transcription | mRNA processing | Genes | Liver | Breast cancer | Genomes | Gene expression | Peptide mapping | Datasets | Proteins | Polyadenylation | Proteomics | Open reading frames | Transcription initiation | Bioinformatics | Index Medicus
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2. Full Text The Genome of the Netherlands: Design, and project goals
by Boomsma, Dorret and Wijmenga, Cisca and Slagboom, Eline and Swertz, Morris and Karssen, Lennart and Abdellaoui, Abdel and Ye, Kai and Guryev, Victor and Vermaat, Joost and Dijk, Freerk and Francioli, Laurent and Hottenga, Jouke Jan and Laros, Jeroen F and Li, Qibin and Li, Yingrui and Cao, Hongzhi and Chen, Ruoyan and Du, Yangchun and Li, Ning and Cao, Sherry and Setten, Jessica and Menelaou, Anoniki and Pulit, Sara and Hehir-Kwa, Jayne and Beekman, Marian and Elbers, Clara and Byelas, Heorhiy and Craen, Anton and Deelen, Patrick and Dijkstra, Martijn and Dunnen, Johan and Knijff, Peter and Houwing-Duistermaat, Jeanine and Koval, Vyacheslav and Estrada Gil, Karol and Hofman, Albert and Kanterakis, Alexanos and Enckevort, David and Mai, Hailiang and Kattenberg, Mathijs and Leeuwen, Elisa and Neerincx, Pieter B T and Oostra, Ben and Rivadeneira Ramirez, Fernando and Suchiman, Eka and Uitterlinden, Ané and Willemsen, Gonneke and Wolffenbuttel, Bruce and Wang, Jinxia and Bakker, Paul and Ommen, Gert and Duijn, Cornelia
European journal of human genetics : EJHG, ISSN 1018-4813, 02/2014, Volume 22, Issue 2, pp. 221 - 227
trio-design | population genetics | whole-genome sequence | Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Gene Frequency | Humans | Middle Aged | Phylogeography | Databases, Genetic | Male | Sequence Analysis, DNA | Genetic Variation | Young Adult | Netherlands | Aged, 80 and over | Adult | Female | Aged | High-Throughput Nucleotide Sequencing | Genome, Human | Haplotypes | Phenotypes | Nucleotide sequence | Principal components analysis | Genomes | Mitochondrial DNA | Genetic diversity | Birth | Epidemiology | Blood | Studies | Progeny | Population | Genetics | Diabetes | Mutation | Variation | Bioinformatics | Deoxyribonucleic acid--DNA | DNA sequencing | Index Medicus
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3. Full Text Next Generation HGVS Nomenclature Checker
by Lefter, Mihai and Vis, Jonathan K and Vermaat, Martijn and den Dunnen, Johan T and Taschner, Peter E M and Laros, Jeroen F J
Bioinformatics (Oxford, England), ISSN 1367-4803, 02/2021
Index Medicus
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4. Full Text Late Release of Circulating Endothelial Cells and Endothelial Progenitor Cells after Chemotherapy Predicts Response and Survival in Cancer Patients
by Roodhart, Jeanine M and Langenberg, Marlies H and Vermaat, Joost S and Lolkema, Martijn P and Baars, Arnold and Giles, Rachel H and Witteveen, Els O and Voest, Emile E
Neoplasia (New York, N.Y.), ISSN 1476-5586, 01/2010, Volume 12, Issue 1, pp. 87 - 94
Life Sciences & Biomedicine | Oncology | Science & Technology | Peptides - blood | Prognosis | Cell Count | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Stem Cells - cytology | Stem Cells - metabolism | Flow Cytometry | Neoplasms - blood | Time Factors | Aged, 80 and over | Adult | Female | Enzyme-Linked Immunosorbent Assay | Endothelial Cells - metabolism | Platelet Endothelial Cell Adhesion Molecule-1 - blood | Vascular Endothelial Growth Factor A - blood | Treatment Outcome | Glycoproteins - blood | AC133 Antigen | Neoplasms - drug therapy | Regression Analysis | Antigens, CD - blood | Endothelial Cells - cytology | Fibroblast Growth Factors - blood | Chemokine CXCL12 - blood | Survival Analysis | Stem Cells - drug effects | Aged | Neoplasms - pathology | Endothelial Cells - drug effects | Index Medicus
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5. Full Text WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene
by Nersisyan, Lilit and Nikoghosyan, Maria and Arakelyan, Arsen and Francioli, Laurent and Menelaou, A and Pulit, S.L and Elbers, C.C and Kloosterman, Wigard and van Setten, J and Nijman, Isaac and Renkens, Ivo and de Bakker, P.I.W and Dijk, Freerk and Neerincx, Pieter and Deelen, Patrick and Kanterakis, Alexanos and Dijkstra, Martijn and Byelas, H and van der Velde, K.J and Platteel, Mathieu and Swertz, M.A and Wijmenga, Cisca and Palamara, P.F and Pe’er, I and Ye, K and Lameijer, Eric-Wubbo and Moed, M.H and Beekman, M and Craen, Anton and Suchiman, H.E.D and Slagboom, Eline and Guryev, Victor and Abdellaoui, Abdel and Jan Hottenga, J and Kattenberg, M and Willemsen, Gonneke and Boomsma, Dorret and van Leeuwen, E.M and Karssen, Lennart and Amin, N and Rivadeneira, F and Isaacs, A and Hofman, A and Uitterlinden, Ané and Duijn, Cornelia and van Oven, M and Kayser, M and Vermaat, Martijn and Laros, Jeroen and Dunnen, Johan and Enckevort, David and Mei, Hailiang and Li, M and Stoneking, M and Schaik, Barbera and Bot, Jan and Marschall, Tobias and Schönhuth, Alexander and Hehir-Kwa, Jayne and Handsaker, Robert and Polak, P and Sohail, M and Vuzman, D and Estrada, Karol and McCarroll, S.A and Sunyaev, S.R and Hormozdiari, Fereydoun and Koval, Vyacheslav and Medina-Gomez, C and Oostra, B and Veldink, Jan and van den Berg, L.H and Pitts, S.J and Potluri, S and Sundar, P and Cox, D.R and Knijff, Peter and Li, Q and Li, Y and Du, Yuanping and Chen, Ruoyan and Cao, H and Wang, J and Li, N and Cao, S and Bovenberg, Jasper and Ommen, Gert-Jan and The Genome of the Netherlands Consortium
Scientific reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1
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6. Full Text WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene
by Nersisyan, L and Nikoghosyan, M and Arakelyan, A and Francioli, Laurent and Menelaou, Anoniki and Pulit, Sara and Elbers, Clara and Kloosterman, Wigard and Setten, Jessica and Nijman, Isaac and Renkens, Ivo and de Bakker, P.I.W and Dijk, Freerk and Neerincx, Pieter B T and Deelen, Patrick and Kanterakis, Alexanos and Dijkstra, Martijn and Byelas, Heorhiy and van der Velde, K.J and Platteel, Inge and Swertz, M.A and Wijmenga, Cisca and Palamara, Pier Francesco and Peer, Itsik and Ye, K and Lameijer, Eric-Wubbo and Moed, Heleen and Beekman, M and Craen, Anton and Suchiman, H.E.D and Slagboom, Eline and Guryev, Victor and Abdellaoui, Abdel and Hottenga, Jouke Jan and Kattenberg, Mathijs and Willemsen, Gonneke and Boomsma, Dorret and van Leeuwen, E.M and Karssen, Lennart and Amin, N and Rivadeneira, F and Isaacs, Aaron and Hofman, A and Uitterlinden, Ané and Duijn, Cornelia and Oven, Mannis and Kayser, Manfred and Vermaat, Martijn and Laros, Jeroen F and Dunnen, Johan and Enckevort, David and Mei, Shan and Li, Mingkun and Stoneking, Mark and Schaik, Barbera and Bot, Jan and Marschall, Tanja and Schönhuth, A and Hehir-Kwa, Jayne and Handsaker, Robert and Polak, P and Sohail, Mashaal and Vuzman, Dana and Estrada Gil, Karol and McCarroll, Steve and Sunyaev, Shamil and Hormozdiari, Fereydoun and Koval, Vyacheslav and Medina-Gomez, Carolina and Oostra, Ben and Veldink, Jan and Berg, Leonard and Pitts, Steven J and Potluri, Shobha and Sundar, Purnima and Cox, David and Knijff, Peter and Li, Q and Li, Yingrui and Du, Yuanping and Chen, Ruoyan and Cao, H and Wang, J and Li, N and Cao, S and Bovenberg, Jasper and Ommen, Gert
Scientific reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1
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7. Full Text A framework for the detection of de novo mutations in family-based sequencing data
by Francioli, Laurent and Cretu-Stancu, Mircea and Garimella, Kiran and Fromer, Menachem and Kloosterman, Wigard and Genome of the Netherlands Consortium and Samocha, Kaitlin and Neale, Benjamin and Daly, Mark and Banks, Eric and DePristo, Mark and Bakker, Paul and Genome Netherlands Consortium and Genome of the Netherlands consortium and Genome of the Netherlands consortium44
European journal of human genetics : EJHG, ISSN 1018-4813, 02/2017, Volume 25, Issue 2, pp. 227 - 233
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Chromosomes, Human, X - genetics | Humans | Genotype | Male | Exome | Pedigree | Germ-Line Mutation | Adult | Female | Models, Genetic | Polymorphism, Single Nucleotide | Software | Genome-Wide Association Study - methods | Child | Sequence Analysis, DNA - methods | Parameter estimation | Nucleotide sequence | Families & family life | Licenses | Genomes | Consortia | Autism | Progeny | Parents & parenting | X Chromosomes | Population | Genetics | Mutation | Bioinformatics | Chromosomes | Deoxyribonucleic acid--DNA | Genotypes | DNA sequencing | Index Medicus
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8. Full Text Controlling bias and inflation in epigenome- and transcriptome-wide association studies using the empirical null distribution
by Iterson, Maarten and Zwet, Erik and Heijmans, Bastiaan and t Hoen, P.A.C and Meurs, Joyce and Jansen, R and Franke, Lude and Boomsma, Dorret and Pool, Reńe and Dongen, Jenny and Hottenga, Jouke Jan and Greevenbroek, M.M and Stehouwer, Coen and Kallen, C.J and Schalkwijk, Casper and Wijmenga, Cisca and Zhernakova, S and Tigchelaar, Ettje F and Slagboom, Eline and Beekman, Marian and Deelen, Joris and Heemst, Diana and Veldink, Jan and Berg, Leonard and Duijn, Cornelia and Hofman, B and Isaacs, Aaron and Uitterlinden, Ané and Jhamai, Mila and Verbiest, Michael and Suchiman, Eka and Verkerk, Marijn and Breggen, Ruud and Van Rooij, Jeroen and Lakenberg, Nico and Mei, Shan and Van Galen, Michiel and Bot, Jan and Zhernakova, Alexana and van 't Hof, Peter and Deelen, Patrick and Nooren, I and Moed, Heleen and Vermaat, Martijn and Luijk, René and Bonder, Marc and Dijk, Freerk and Arinarto, Wibowo and Kielbasa, Szymon M and Swertz, M.A and t Hoen, P.-B and BIOS Consortium and the BIOS Consortium
Genome Biology, ISSN 1474-7596, 01/2017, Volume 18, Issue 1, pp. 19 - 19
Gibbs sampler | Empirical null distribution | Inflation | Bias | Epigenome- and transcriptome-wide association studies | Meta-analysis | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Meta-Analysis as Topic | Age Factors | Epigenomics - methods | Epigenesis, Genetic | Humans | Bayes Theorem | Transcriptome | Epigenomics - standards | Genome-Wide Association Study - methods | Smoking | Studies | Quality control | DNA methylation | Genomes | Gene expression | Statistics | Bayesian analysis | Bioinformatics | Deoxyribonucleic acid--DNA | Methods | Index Medicus
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9. Full Text A linear mixed-model approach to study multivariate gene-environment interactions
by Moore, Rachel and Casale, Francesco Paolo and Jan Bonder, Marc and Horta, Danilo and Heijmans, Bastiaan T and C.’t Hoen, Peter A and van Meurs, Joyce and Isaacs, Aaron and Jansen, Rick and Franke, Lude and Boomsma, Dorret I and Pool, René and van Dongen, Jenny and Hottenga, Jouke J and van Greevenbroek, Marleen M. J and Stehouwer, Coen D. A and van der Kallen, Carla J. H and Schalkwijk, Casper G and Wijmenga, Cisca and Zhernakova, Alexandra and Tigchelaar, Ettje F and Slagboom, P. Eline and Beekman, Marian and Deelen, Joris and van Heemst, Diana and Veldink, Jan H and van den Berg, Leonard H and van Duijn, Cornelia M and Hofman, Bert A and Uitterlinden, André G and Jhamai, P. Mila and Verbiest, Michael and Suchiman, H. Eka D and Verkerk, Marijn and van der Breggen, Ruud and van Rooij, Jeroen and Lakenberg, Nico and Mei, Hailiang and van Iterson, Maarten and van Galen, Michiel and Bot, Jan and van’t Hof, Peter and Deelen, Patrick and Nooren, Irene and Moed, Matthijs and Vermaat, Martijn and Zhernakova, Dasha V and Luijk, René and Jan Bonder, Marc and van Dijk, Freerk and Arindrarto, Wibowo and Kielbasa, Szymon M and Swertz, Morris A and van Zwet, Erik W and Franke, Lude and Barroso, Inês and Stegle, Oliver and BIOS Consortium
Nature genetics, ISSN 1061-4036, 01/2019, Volume 51, Issue 1, pp. 180 - 186
TESTS | OBESITY | SET | VARIANTS | BODY-MASS INDEX | LOCI | TRAITS | MULTIPLE | GENOME-WIDE ASSOCIATION | BMI | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Algorithms | Computer Simulation | Humans | Environment | Genotype | Linear Models | Models, Genetic | Gene-Environment Interaction | Quantitative Trait Loci - genetics | Linear models (Statistics) | Usage | Research | Genetic variation | Linear regression models | Environmental impact analysis | Obesity | Physical activity | Disease | Computer simulation | Data processing | Principal components analysis | Genomes | Exposure | Gene expression | Loci | Body mass index | Body mass | Body size | Genotype-environment interactions | Population | Power | Genotypes | Index Medicus
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10. Full Text A high-quality human reference panel reveals the complexity and distribution of genomic structural variants
by Hehir-Kwa, Jayne Y and Marschall, Tobias and Kloosterman, Wigard P and Francioli, Laurent C and Baaijens, Jasmijn A and Dijkstra, Louis J and Abdellaoui, Abdel and Koval, Vyacheslav and Thung, Djie Tjwan and Wardenaar, René and Renkens, Ivo and Coe, Bradley P and Deelen, Patrick and De Ligt, Joep and Lameijer, Eric Wubbo and Van Dijk, Freerk and Hormozdiari, Fereydoun and Uitterlinden, Ané G and Van Duijn, Cornelia M and Eichler, Evan E and De Bakker, Paul I.W and Swertz, Morris A and Wijmenga, Cisca and Van Ommen, Gert Jan B and Slagboom, P. Eline and Boomsma, Dorret I and Schönhuth, Alexander and Ye, Kai and Guryev, Victor and Bovenberg, Jasper A and De Craen, Anton J M and Beekman, Marian and Hofman, Albert and Willemsen, Gonneke and Wolffenbuttel, Bruce and Platteel, Mathieu and Du, Yuanping and Chen, Ruoyan and Cao, Hongzhi and Cao, Rui and Sun, Yushen and Cao, Jeremy Sujie and Neerincx, Pieter B T and Dijkstra, Martijn and Byelas, George and Kanterakis, Alexanos and Bot, Jan and Vermaat, Martijn and Laros, Jeroen F and den Dunnen, Johan T and De Knijff, Peter and Karssen, Lennart C and Van Leeuwen, Elisa M and Amin, Najaf and Rivadeneira, Fernando and Estrada, Karol and Hottenga, Jouke-Jan and Kattenberg, V. Mathijs and Van Enckevort, David and Mei, Hailiang and Santcroos, Mark and Van Schaik, Barbera D C and Handsaker, Robert E and McCarroll, Steven A and Ko, Arthur and Sudmant, Peter and Nijman, Isaac J
Nature communications, ISSN 2041-1723, 10/2016, Volume 7
Haplotypes | Genome informatics | Next-generation sequencing | Structural variation | Physics and Astronomy(all) | Chemistry(all) | Biochemistry, Genetics and Molecular Biology(all) | Journal Article
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11. Full Text Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations
by Shah, Sonia and Bonder, Marc J and Marioni, Riccardo E and Zhu, Zhihong and McRae, Allan F and Zhernakova, Alexandra and Harris, Sarah E and Liewald, Dave and Henders, Anjali K and Mendelson, Michael M and Liu, Chunyu and Joehanes, Roby and Liang, Liming and Heijmans, Bastiaan T and ’t Hoen, Peter A.C and van Meurs, Joyce and Isaacs, Aaron and Jansen, Rick and Franke, Lude and Boomsma, Dorret I and Pool, René and van Dongen, Jenny and Hottenga, Jouke J and van Greevenbroek, Marleen M.J and Stehouwer, Coen D.A and van der Kallen, Carla J.H and Schalkwijk, Casper G and Wijmenga, Cisca and Zhernakova, Sasha and Tigchelaar, Ettje F and Slagboom, P. Eline and Beekman, Marian and Deelen, Joris and van Heemst, Diana and Veldink, Jan H and van den Berg, Leonard H and van Duijn, Cornelia M and Hofman, Bert A and Uitterlinden, André G and Jhamai, P. Mila and Verbiest, Michael and Suchiman, H. Eka D and Verkerk, Marijn and van der Breggen, Ruud and van Rooij, Jeroen and Lakenberg, Nico and Mei, Hailiang and van Iterson, Maarten and van Galen, Michiel and Bot, Jan and van ’t Hof, Peter and Deelen, Patrick and Nooren, Irene and Moed, Matthijs and Vermaat, Martijn and Zhernakova, Dasha V and Luijk, René and Bonder, Marc Jan and van Dijk, Freerk and Arindrarto, Wibowo and Kielbasa, Szymon M and Swertz, Morris A and van Zwet, Erik W and Levy, Daniel and Martin, Nicholas G and Starr, John M and Wijmenga, Cisca and Wray, Naomi R and Yang, Jian and Montgomery, Grant W and Franke, Lude and Deary, Ian J and Visscher, Peter M and BIOS Consortium
American journal of human genetics, ISSN 0002-9297, 07/2015, Volume 97, Issue 1, pp. 75 - 85
POPULATION | OBESITY | DNA METHYLATION | GENOTYPE IMPUTATION | WEIGHT-LOSS | CARDIOVASCULAR-DISEASE | BODY-MASS INDEX | WIDE ASSOCIATION | HEIGHT | GENOME | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Body Mass Index | Humans | Middle Aged | Genotype | Scotland | DNA Methylation - genetics | Obesity - genetics | Body Height - genetics | Netherlands | Phenotype | Analysis of Variance | Adolescent | Adult | Models, Genetic | Genome-Wide Association Study - methods | Cohort Studies | Epigenetic inheritance | Body mass index | Genetic aspects | Nucleotide sequencing | Identification and classification | Methods | DNA sequencing | DNA methylation | Epigenetics | Genotype & phenotype | Genomes | Index Medicus
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12. Full Text Transmission of human mtDNA heteroplasmy in the genome of the Netherlands families : Support for a variable-size bottleneck
by Li, Mingkun and Rothwell, Rebecca and Vermaat, Martijn and Wachsmuth, Manja and Schröder, Roland and Laros, Jeroen F J and Van Oven, Mannis and De Bakker, Paul I W and Bovenberg, Jasper A and Van Duijn, Cornelia M and Van Ommen, Gert Jan B and Slagboom, P. Eline and Swertz, Morris A and Wijmenga, Cisca and Kayser, Manfred and Boomsma, Dorret I and Zöllner, Sebastian and De Knijff, Peter and Stoneking, Mark and De Craen, Anton J M and Beekman, Marian and Hofman, Albert and Willemsen, Gonneke and Wolffenbuttel, Bruce and Platteel, Mathieu and Du, Yuanping and Chen, Ruoyan and Cao, Hongzhi and Cao, Rui and Sun, Yushen and Cao, Jeremy Sujie and Van Dijk, Freerk and Neerincx, Pieter B T and Deelen, Patrick and Dijkstra, Martijn and Byelas, George and Kanterakis, Alexanos and Bot, Jan and Ye, Kai and Lameijer, Eric Wubbo and Den Dunnen, Johan T and Karssen, Lennart C and Van Leeuwen, Elisa M and Amin, Najaf and Koval, Vyacheslav and Rivadeneira, Fernando and Estrada, Karol and Hehir-Kwa, Jayne Y and De Ligt, Joep and Abdellaoui, Abdel and Hottenga, Jouke Jan and Kattenberg, V. Mathijs and Van Enckevort, David and Mei, Hailiang and Santcroos, Mark and Van Schaik, Barbera D C and Handsaker, Robert E and McCarroll, Steven A and Eichler, Evan E and Ko, Arthur and Sudmant, Peter and Francioli, Laurent C and Kloosterman, Wigard P and Nijman, Isaac J and Guryev, Victor
Genome research, ISSN 1088-9051, 04/2016, Volume 26, Issue 4, p. 417
Genetics(clinical) | Research Support, Non-U.S. Gov't | Twin Study | Genetics | Journal Article
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