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Journal Article
eLife, ISSN 2050-084X, 12/2018, Volume 7
Interferon (IFN) inhibits HIV replication by inducing antiviral effectors. To comprehensively identify IFN-induced HIV restriction factors, we assembled a... 
CRISPR | HIV | infectious disease | virus replication | microbiology | restriction factor | screen | interferon-stimulated genes | virus | TYPE-1 REPLICATION | HUMAN TRIM5-ALPHA | PROTEIN | GENE | CELL SPREAD | RESTRICTION FACTORS | BIOLOGY | INFECTION | HUMAN-IMMUNODEFICIENCY-VIRUS | ADAPTIVE EVOLUTION | T-CELLS | Antigens, CD - immunology | Interferon-alpha - pharmacology | Phosphotransferases (Alcohol Group Acceptor) - immunology | Epithelial Cells - drug effects | Humans | Receptors, CCR5 - genetics | Antigens, CD - genetics | Receptors, CCR5 - immunology | Lentivirus - metabolism | HIV-1 - growth & development | Nuclear Proteins - deficiency | HEK293 Cells | Lentivirus - genetics | Receptors, CXCR4 - genetics | Nuclear Proteins - genetics | Carrier Proteins - immunology | Viral Tropism - genetics | Virus Replication - drug effects | GPI-Linked Proteins - immunology | Genetic Vectors - chemistry | Genetic Vectors - immunology | Signal Transduction | HIV-1 - drug effects | Myxovirus Resistance Proteins - immunology | Phosphotransferases (Alcohol Group Acceptor) - deficiency | Gene Expression Regulation | THP-1 Cells | Phosphotransferases (Alcohol Group Acceptor) - genetics | HIV-1 - genetics | Nuclear Proteins - immunology | Host-Pathogen Interactions | Carrier Proteins - genetics | HIV-1 - immunology | Receptors, CXCR4 - immunology | Epithelial Cells - immunology | Epithelial Cells - virology | CRISPR-Cas Systems | Cell Line, Tumor | Virus Assembly - drug effects | Antigens, Differentiation - genetics | Gene Editing - methods | Myxovirus Resistance Proteins - genetics | Antigens, Differentiation - immunology | GPI-Linked Proteins - genetics | Interferon | Genetic aspects | Nucleotide sequencing | HIV (Viruses) | Health aspects | Methods | DNA sequencing | Medical research | Flow cytometry | CCR5 protein | Genomics | Genes | Viruses | Infections | Genomes | CXCR4 protein | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Packaging | Mutation | Budding | Adaptation
Journal Article
Cell Reports, ISSN 2211-1247, 10/2016, Volume 17, Issue 2, pp. 413 - 424
Several pattern-recognition receptors sense HIV-1 replication products and induce type I interferon (IFN-I) production under specific experimental conditions.... 
NF-κB | CD4 | dendritic cells | innate sensing | HIV | cGAS | Vpr | Vpu | interferon | T cells | REPLICATION | DENDRITIC CELLS | IMMUNODEFICIENCY-VIRUS TYPE-1 | INNATE IMMUNE-RESPONSE | SENSOR | INFECTION | NF-KAPPA-B | PROTEIN-R | EXPRESSION | DISEASE PROGRESSION | CELL BIOLOGY
Journal Article
Journal Article
Journal Article
Retrovirology, ISSN 1742-4690, 12/2014, Volume 11, Issue 1
Background: Down-modulation of the CD4 receptor is one of the hallmarks of HIV-1 infection and it is believed to confer a selective replicative advantage to... 
HIV-1 | CD4 | Endocytosis | shRNA | Nef | ADAPTER PROTEIN COMPLEX-2 | NEF PROTEIN | LARGE GENE LISTS | REPLICATION | VIROLOGY | IMMUNODEFICIENCY-VIRUS TYPE-1 | VPU PROTEIN | HIV NEF | INTERFERENCE | T-CELLS | MODULATION | Medical equipment and supplies industry | Clathrin | Epidermal growth factor | Viral proteins | Medical test kit industry | Heat shock proteins | T cells
Journal Article
Retrovirology, ISSN 1742-4690, 12/2011, Volume 8, Issue S2, pp. P43 - P43
Journal Article
Retrovirology, ISSN 1742-4690, 04/2012, Volume 9, Issue 1, pp. 34 - 34
Background: The Nef protein of HIV facilitates virus replication and disease progression in infected patients. This role as pathogenesis factor depends on... 
HIV | Lck | Infectivity | Sequence motifs | Cytoskeleton | Replication | SH3 domain binding | Nef | Receptor downregulation | AIDS-LIKE DISEASE | MAJOR CORECEPTOR | HUMAN-IMMUNODEFICIENCY-VIRUS | TYPE-1 NEF | VIROLOGY | I DOWN-REGULATION | MHC-I | T-CELL DEVELOPMENT | IMMUNOLOGICAL SYNAPSE | PRIMATE LENTIVIRUSES | TRANSGENIC MICE | Sequence Deletion | Glycine - metabolism | HIV-1 - pathogenicity | Humans | Structure-Activity Relationship | trans-Golgi Network - metabolism | Lymphocytes - virology | Conserved Sequence | nef Gene Products, Human Immunodeficiency Virus - metabolism | Receptors, CXCR4 - genetics | Glycine - genetics | Lymphocytes - metabolism | Amino Acid Sequence | HIV-1 - metabolism | Actin Cytoskeleton - metabolism | Phenylalanine - metabolism | p21-Activated Kinases - genetics | Signal Transduction | Jurkat Cells | HIV Infections - virology | Proto-Oncogene Proteins c-hck - metabolism | HIV-1 - genetics | p21-Activated Kinases - metabolism | Amino Acid Motifs | Receptors, CXCR4 - metabolism | Host-Pathogen Interactions | Valine - metabolism | Virus Replication | nef Gene Products, Human Immunodeficiency Virus - genetics | Phenylalanine - genetics | Alleles | Proto-Oncogene Proteins c-hck - genetics | Valine - genetics | Genes, MHC Class I | HeLa Cells | HIV Infections - metabolism | Viral proteins | Development and progression | Amino acids | Cellular signal transduction | HIV (Viruses) | Muscle proteins | Protein-protein interactions
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1
Figure 1 is missing Panel C. The correct version of Figure 1 can be found here: thumbnail Download: * PPT PowerPoint slide * PNG larger image * TIFF original... 
Chronic lymphatic leukemia | Cell activation | Lymphocytes B | Ribonucleic acids | MicroRNAs | Cell cycle | MiRNA | T cell receptors | mRNA | Myc protein | B-cell receptor
Journal Article
Journal of Clinical Microbiology, ISSN 0095-1137, 02/2015, Volume 53, Issue 2, pp. 699 - 701
Episomal HIV-1 two-long terminal repeat (2-LTR) circles are considered markers for ongoing viral replication. Two sample processing procedures were compared to... 
MICROBIOLOGY | Humans | DNA, Viral - isolation & purification | DNA, Viral - analysis | HIV-1 - genetics | Plasmids - analysis | Terminal Repeat Sequences | Plasmids - isolation & purification | Polymerase Chain Reaction - methods | Virology
Journal Article
British Journal of Haematology, ISSN 0007-1048, 12/2013, Volume 163, Issue 5, pp. 621 - 630
Summary Chronic lymphocytic leukaemia (CLL) is a disease with a highly variable prognosis. The clinical course can however be predicted thanks to prognostic... 
chronic lymphocytic leukaemia | zeta‐associated protein of 70 | B‐cell receptor | nuclear factor‐κB | Chronic lymphocytic leukaemia | Zeta-associated protein of 70 | B-cell receptor | Nuclear factor-κB | zeta-associated protein of 70 | nuclear factor-B | MESSENGER-RNA EXPRESSION | MUTATION STATUS | ANTIGEN-RECEPTOR | THERAPEUTIC TARGET | GENE-EXPRESSION | CD38 EXPRESSION | ZAP-70 EXPRESSION | PROGNOSTIC MARKERS | CELL-RECEPTOR | HEMATOLOGY | DISEASE PROGRESSION | Interleukin-8 - genetics | Transcription Factor RelA - physiology | Prognosis | Humans | Middle Aged | Neoplasm Proteins - physiology | Transcriptome | ZAP-70 Protein-Tyrosine Kinase - biosynthesis | Male | NF-kappa B - metabolism | Interleukin-1beta - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Immunoglobulin M - immunology | Recombinant Fusion Proteins - metabolism | I-kappa B Kinase - physiology | Quinoxalines - pharmacology | Interleukins - genetics | I-kappa B Kinase - antagonists & inhibitors | Adult | Female | Interleukin-1beta - biosynthesis | Interleukins - biosynthesis | Tumor Cells, Cultured | Neoplasm Proteins - genetics | Calcium Signaling | Interleukin-6 - genetics | Interleukin-8 - biosynthesis | Jurkat Cells | Neoplasm Proteins - biosynthesis | RNA, Messenger - genetics | ZAP-70 Protein-Tyrosine Kinase - physiology | ZAP-70 Protein-Tyrosine Kinase - genetics | Electroporation | Imidazoles - pharmacology | Gene Expression Regulation, Leukemic | Receptors, Antigen, B-Cell - immunology | Interleukin-6 - biosynthesis | Immunoglobulin Variable Region - genetics | Aged | Immunoglobulin Heavy Chains - genetics
Journal Article