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PLoS ONE, ISSN 1932-6203, 05/2009, Volume 4, Issue 5, pp. e5622 - e5622
Background: The INK4/ARF locus encodes three tumor suppressor genes (p15(Ink4b), Arf and p16(Ink4a)) and is frequently inactivated in a large number of human... 
BIOLOGY | NIH 3T3 Cells | Myeloid-Lymphoid Leukemia Protein - metabolism | Cellular Senescence | Repressor Proteins - metabolism | Fibroblasts - metabolism | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Cell Cycle Proteins - metabolism | Gene Silencing | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Nuclear Proteins - metabolism | Polycomb-Group Proteins | Enhancer of Zeste Homolog 2 Protein | Polycomb Repressive Complex 2 | Animals | Cyclin-Dependent Kinase Inhibitor p16 - chemistry | Polycomb Repressive Complex 1 | Histone-Lysine N-Methyltransferase - metabolism | Embryo, Mammalian - cytology | Models, Biological | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Protein Binding | DNA Replication Timing | Fibroblasts - cytology | Mice | Histones - metabolism | Methylation | Proteins | Epigenetic inheritance | DNA replication | Senescence | Chromatin | Genes | INK4a protein | Genomes | Recruitment | Cell growth | Transcription activation | Cell cycle | Fibroblasts | Cyclin-dependent kinase inhibitors | Deoxyribonucleic acid--DNA | p16 Protein | INK4 protein | Embryo fibroblasts | Gene expression | Embryos | Loci | DNA biosynthesis | Polycomb group proteins | Replication origins | Pilot projects | Insects | Stem cells | Epigenetics | Tumor suppressor genes | Replication | Embryo, Mammalian | Histone-Lysine N-Methyltransferase | Repressor Proteins | Cell Aging | Nuclear Proteins | Cyclin-Dependent Kinase Inhibitor p16 | Life Sciences | Immunology | Histones | Myeloid-Lymphoid Leukemia Protein | Proto-Oncogene Proteins | Cell Cycle Proteins | Deoxyribonucleic acid | DNA
Journal Article
Cell Reports, ISSN 2211-1247, 11/2017, Volume 21, Issue 9, pp. 2515 - 2527
The spleen plays an important role in protective immunity to bloodborne pathogens. Macrophages and dendritic cells (DCs) in the spleen marginal zone capture... 
NF-κB | macrophages | dendritic cells | innate immunity | inflammation | marginal zone | CD169 | adaptive immunity | LISTERIA-MONOCYTOGENES | FAMILY-MEMBER | HOMEOSTASIS | DENDRITIC CELLS | IN-VIVO | INFECTION | MICE | CD169(+) MACROPHAGES | SECONDARY LYMPHOID ORGANS | SUBCAPSULAR SINUS MACROPHAGES | CELL BIOLOGY
Journal Article
Journal Article
Cell Metabolism, ISSN 1550-4131, 06/2019, Volume 29, Issue 6, pp. 1376 - 1389.e4
Macrophages possess intrinsic tumoricidal activity, yet tumor-associated macrophages (TAMs) rapidly adopt an alternative phenotype within the tumor... 
lipid rafts | cholesterol efflux | ovarian cancer | IL-4 signaling | tumor-associated macrophages | Medical research | Analysis | Medicine, Experimental | Development and progression | Research institutes | Metastasis | Macrophages | Gene expression | Cholesterol | Cancer | Ovarian cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2008, Volume 3, Issue 10, p. e3467
Actin polymerization plays a critical role in activated T lymphocytes both in regulating T cell receptor (TCR)-induced immunological synapse (IS) formation and... 
Phosphorylation | Homeostasis | Activation | Immunological synapses | Lymphocytes T | Kinases | Machinery | Calcium influx | Cell adhesion & migration | Proteins | T-cell receptor | Cell activation | Immunology | Gene targeting | Lymphocytes | Actin | Rodents | Cell adhesion | NF-κB protein | Antigens | Cell survival | Cytokines | Polymerization | JNK protein | T cell receptors | Hemopoiesis | Cytoskeleton | Ligands | Mice
Journal Article
PLOS ONE, ISSN 1932-6203, 10/2008, Volume 3, Issue 10, p. e3467
Journal Article
Immunity, ISSN 1074-7613, 04/2015, Volume 42, Issue 4, p. 627
Migratory non-lymphoid tissue dendritic cells (NLT-DCs) transport antigens to lymph nodes (LNs) and are required for protective immune responses in the context... 
Autoimmunity | Homeostasis | Dendritic cells | T cells | Flow cytometry | Microorganisms | Lymphocytes | Rodents | Migration | Morphology | Colleges & universities | Autoimmune diseases | Gene expression | Experiments | Binding sites
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/1996, Volume 93, Issue 15, pp. 7877 - 7881
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 02/2005, Volume 25, Issue 4, pp. 1437 - 1445
Journal Article
The Journal of Immunology, ISSN 0022-1767, 12/2009, Volume 183, Issue 12, p. 7939
The TCRbeta gene enhancer (Ebeta) commands TCRbeta gene expression through the lifespan of T lymphocytes. Genetic and molecular studies have implied that in... 
Life Sciences | Immunology
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/1996, Volume 93, Issue 15, pp. 7877 - 7881
Intrathymic T-cell development requires temporally regulated rearrangement and expression of T-cell receptor (TCR) genes. To assess the role of the TCR β gene... 
T lymphocytes | Polymerase chain reaction | Germ cells | Thymocytes | Epithelial cells | B lymphocytes | Genes | Genetic loci | Lymph nodes | T cell antigen receptors | REARRANGEMENT | transcription | cis-regulatory element | MULTIDISCIPLINARY SCIENCES | V(D)J recombination | gene targeting | MICE | CHAIN INTRON ENHANCER | LINEAGE | LYMPHOCYTES | Receptors | Genetic transcription | Research | T cells
Journal Article
International Immunology, ISSN 0953-8178, 02/2004, Volume 16, Issue 2, pp. 231 - 240
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2000, Volume 165, Issue 3, pp. 1364 - 1373
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/1997, Volume 94, Issue 15, pp. 8088 - 8092
Natural killer (NK) cells express killer cell inhibitory receptors (KIRs) for major histocompatibility complex class I molecules. Engagement of these surface... 
T lymphocytes | Molecules | Receptors | Transgenic animals | Bone marrow | Ligands | Natural killer cells | Transgenes | Graft rejection | Tissue grafting
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 02/2005, Volume 25, Issue 4, pp. 1437 - 1445
The Notch signaling pathway controls several cell fate decisions during lymphocyte development, from T-cell lineage commitment to the peripheral... 
Journal Article
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