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NATURE GENETICS, ISSN 1061-4036, 05/2019, Volume 51, Issue 5, pp. 777 - 777
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2019, Volume 294, Issue 11, pp. 3974 - 3986
Hypoxia-inducible factor 2 (HIF2) directly regulates a battery of genes essential for intestinal iron absorption. Interestingly, iron deficiency and overload... 
hypoxia | HYPOXIA-INDUCIBLE FACTOR | DOMAIN | TGF-BETA | HIF | PHOSPHORYLATION | DMT1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | FACTOR-I | DNA-BINDING ACTIVITY | iron metabolism | GROWTH-FACTOR-BETA | METABOLISM | STRUCTURAL BASIS | iron | SMAD transcription factor | SMAD | CANCER PROGRESSION | gene expression
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 05/2014, Volume 111, Issue 21, p. 7695
The intestinal stem cell fuels the highest rate of tissue turnover in the body and has been implicated in intestinal disease and cancer; understanding the... 
Cell proliferation | Stem cell research | Stem cells | Physiological aspects | Research
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2014, Volume 111, Issue 21, p. 7695
  The intestinal stem cell fuels the highest rate of tissue turnover in the body and has been implicated in intestinal disease and cancer; understanding the... 
Digestive system | Stem cells | Homeostasis | Physiology | Metabolism | Apoptosis
Journal Article
Nature, ISSN 0028-0836, 10/2010, Volume 467, Issue 7319, pp. 1055 - 1056
In mice, two cell populations manifest the capacity for both prolonged self-renewal and multi-lineage differentiation: rare cells in the fourth tier of the... 
Competition | Binomial distribution | Labeling | Cancer therapies | Stem cells
Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 2016, Volume 151, Issue 2, pp. 228 - 231
Journal Article
Cell Stem Cell, ISSN 1934-5909, 07/2018, Volume 23, Issue 1, pp. 46 - 59.e5
Paneth cells are post-mitotic intestinal epithelial cells supporting the stem cell niche and mucosal immunity. Paneth cell pathologies are observed in various... 
Paneth cell | Lyz1 | intestinal stem cell | lysozyme | RNA-seq | Notch | plasticity | Wnt | PROGENITOR CELLS | FUNCTIONALLY DISTINCT | SECRETORY PRECURSORS | LABEL-RETAINING CELLS | EXPRESSION ANALYSIS | EPITHELIAL-CELLS | INTESTINAL STEM-CELLS | SIGNALING PATHWAY | INTEGRATIVE GENOMICS VIEWER | LATERAL INHIBITION | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2017, Volume 12, Issue 9, p. e0184709
Moringa (Moringa oleifera Lam.) seed extract (MSE) has anti-inflammatory and antioxidant activities. We investigated the effects of MSE enriched in moringa... 
DEXTRAN SULFATE SODIUM | PHENETHYL ISOTHIOCYANATE | OXIDATIVE STRESS | INFLAMMATORY-BOWEL-DISEASE | SULFORAPHANE | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | GENE-EXPRESSION | OLEIFERA LEAVES | CLINICAL-ASPECTS | Plant Extracts - chemistry | Plant Extracts - pharmacology | Male | Claudin-1 - metabolism | Isothiocyanates - chemistry | Seeds - chemistry | Colitis, Ulcerative - drug therapy | Zonula Occludens-1 Protein - metabolism | Spleen - pathology | Isothiocyanates - pharmacology | Tight Junctions - metabolism | Cytokines - metabolism | Colon - pathology | Colitis, Ulcerative - metabolism | Colitis, Ulcerative - pathology | Colon - metabolism | Dextran Sulfate - toxicity | Animals | Lipocalin-2 - metabolism | Spleen - metabolism | Colitis, Ulcerative - chemically induced | NF-E2-Related Factor 2 - metabolism | Mice | Nitric Oxide - metabolism | Chronic Disease | Moringa - chemistry | Tight Junctions - pathology | Nitric Oxide Synthase Type II - metabolism | Peroxidase - metabolism | Care and treatment | Brassica | Usage | Physiological aspects | Research | Ulcerative colitis | Materia medica, Vegetable | Plant extracts | Enrichment | Animal models | Inflammatory bowel diseases | Seeds | Interleukin | Fuel consumption | Interleukin 6 | Antioxidants | Proteins | Signal transduction | Histopathology | Glutathione transferase | Rodents | Interleukin 1 | Dextran sulfate | Biocompatibility | Peroxidase | Bioindicators | Colon | Spleen | Enzymes | Lipocalin | Oral administration | Isothiocyanate | Secretions | Gene expression | Disease control | Nitric-oxide synthase | Inflammatory bowel disease | Dextran | Sodium | Nitric oxide | Minimum inhibitory concentration | Weight reduction | Phase (cyclic) | Biomarkers | Sulfate
Journal Article
Journal Article
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 03/2019, Volume 294, Issue 11, pp. 3974 - 3986
Hypoxia-inducible factor 2α (HIF2α) directly regulates a battery of genes essential for intestinal iron absorption. Interestingly, iron deficiency and overload... 
Smad3 Protein - deficiency | Animals | Basic Helix-Loop-Helix Transcription Factors - metabolism | Humans | Cells, Cultured | Iron-Regulatory Proteins - metabolism | Mice | Smad3 Protein - metabolism | Smad4 Protein - deficiency | Smad4 Protein - metabolism | Iron-Regulatory Proteins - genetics | Mice, Knockout
Journal Article
Development (Cambridge, England), ISSN 0950-1991, 08/2019, Volume 146, Issue 19, p. dev179432
As embryos mature, cells undergo remarkable transitions that are accompanied by shifts in transcription factor regulatory networks. Mechanisms driving... 
Journal Article