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Journal Article
PLoS ONE, ISSN 1932-6203, 01/2010, Volume 5, Issue 1, p. e8575
Journal Article
STEM CELLS, ISSN 1066-5099, 01/2010, Volume 28, Issue 1, pp. 5 - 16
Cancer stem cells (CSCs) are thought to be critical for the engraftment and long‐term growth of many tumors, including glioblastoma (GBM). The cells are at... 
NOTCH | γ‐Secretase inhibitor | Cancer Stem Cell | Glioblastoma | Cancer stem cell | γ-Secretase inhibitor | CANCER-CELLS | SIDE POPULATION | GLIOMA | SELF-RENEWAL | IDENTIFICATION | INTERSTITIAL CHEMOTHERAPY | CELL & TISSUE ENGINEERING | CELL BIOLOGY | STEM-LIKE CELLS | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENES | CENTRAL-NERVOUS-SYSTEM | HEMATOLOGY | EXPRESSION | gamma-Secretase inhibitor | Neurons - pathology | Glioblastoma - enzymology | Phosphorylation | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Brain Neoplasms - pathology | Glycoproteins - metabolism | Neoplastic Stem Cells - immunology | Receptor, Notch2 - genetics | Antigens, CD - metabolism | Dose-Response Relationship, Drug | Brain Neoplasms - immunology | Peptides - metabolism | Transfection | Time Factors | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Female | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Neurons - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Spheroids, Cellular | STAT3 Transcription Factor - metabolism | Brain Neoplasms - enzymology | Enzyme Inhibitors - pharmacology | Neurons - immunology | Receptor, Notch2 - metabolism | Tumor Burden | Brain Neoplasms - drug therapy | AC133 Antigen | Xenograft Model Antitumor Assays | Amyloid Precursor Protein Secretases - metabolism | Animals | Glioblastoma - immunology | Signal Transduction - drug effects | Mice, Nude | Glioblastoma - pathology | Neurons - enzymology | Cell Proliferation - drug effects | Mice | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Glioblastoma - drug therapy | Neoplastic Stem Cells - enzymology
Journal Article
Cancer Research, ISSN 0008-5472, 09/2011, Volume 71, Issue 18, pp. 6061 - 6072
One important function of endothelial cells in glioblastoma multiforme (GBM) is to create a niche that helps promote self-renewal of cancer stem-like cells... 
INITIATING CELLS | DLL4 | ANGIOGENESIS | ONCOLOGY | VASCULAR NICHE | NEUROGENESIS | CENTRAL-NERVOUS-SYSTEM | SUBVENTRICULAR ZONE | PERIVASCULAR NICHE | INHIBITS TUMOR-GROWTH | BRAIN-TUMORS | RNA, Small Interfering - genetics | Nestin | Receptors, Notch - metabolism | Humans | Brain Neoplasms - pathology | Glycoproteins - metabolism | Cell Growth Processes - physiology | Intercellular Signaling Peptides and Proteins - biosynthesis | Receptors, Notch - genetics | Brain Neoplasms - metabolism | Antigens, CD - metabolism | Gene Knockdown Techniques | Membrane Proteins - deficiency | Peptides - metabolism | Neoplastic Stem Cells - metabolism | Receptors, Notch - biosynthesis | Serrate-Jagged Proteins | Neoplastic Stem Cells - pathology | Glioblastoma - metabolism | Intercellular Signaling Peptides and Proteins - deficiency | Receptors, Notch - deficiency | Calcium-Binding Proteins - biosynthesis | Stem Cell Niche | Endothelial Cells - metabolism | Membrane Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Calcium-Binding Proteins - deficiency | AC133 Antigen | Nerve Tissue Proteins - metabolism | Xenograft Model Antitumor Assays | Membrane Proteins - biosynthesis | Animals | Glioblastoma - pathology | Mice | Endothelial Cells - pathology | RNA, Small Interfering - administration & dosage | Intermediate Filament Proteins - metabolism | Calcium-Binding Proteins - genetics | Notch ligand | Endothelial cell | niche | glioblastoma | cancer stem cell
Journal Article
STEM CELLS, ISSN 1066-5099, 10/2007, Volume 25, Issue 10, pp. 2524 - 2533
Journal Article
Nature, ISSN 0028-0836, 04/2003, Volume 422, Issue 6933, pp. 688 - 694
Journal Article
Journal of Translational Medicine, ISSN 1479-5876, 12/2015, Volume 13, Issue 1, pp. 17 - 17
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 04/2019, Volume 116, Issue 15, pp. 7483 - 7492
Three-dimensional cell cultures are leading the way to the fabrication of tissue-like constructs useful to developmental biology and pharmaceutical screenings.... 
spinal cord injury | FUNCTIONAL RECOVERY | LOCALIZATION | neural stem cells | MULTIDISCIPLINARY SCIENCES | MICROTUBULE-ASSOCIATED PROTEIN-2 | NEURONAL DIFFERENTIATION | HIPPOCAMPAL-NEURONS | ORGANOIDS | IN-VIVO MODEL | MICROENVIRONMENT | self-assembling peptides | nervous tissue engineering | STEM-CELL TRANSPLANTATION | 3D cell cultures | Cell Proliferation | Spinal Cord Injuries - metabolism | Cholinergic Neurons - metabolism | Humans | Cells, Immobilized - metabolism | Rats | Neural Stem Cells - pathology | Rats, Sprague-Dawley | Cells, Immobilized - pathology | Spinal Cord Injuries - pathology | Regeneration | Animals | Heterografts | Neural Stem Cells - transplantation | Female | Cell Differentiation | Cells, Immobilized - transplantation | Hydrogels - pharmacology | Spinal Cord Injuries - therapy | Cholinergic Neurons - pathology | Neural Stem Cells - metabolism | Hydrogels - chemistry | Disease Models, Animal | Cell proliferation | Cell culture | Surgical implants | Spinal cord | Media (culture) | Hydrogels | Spinal cord injury | Tissues | Biomaterials | Fabrication | γ-Aminobutyric acid | Biomedical materials | Injuries | Immune system | Immune response | Maturation | Developmental biology | Cultures | Cholinergics | Progeny | Gliosis | Reproducibility | Neural networks | Stem cells | Culture media | Neural stem cells | Spinal cord injuries | Glutamatergic transmission | Biological Sciences | PNAS Plus
Journal Article