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1. Full Text Identification of seven loci affecting mean telomere length and their association with disease
by Codd, Veryan and Nelson, Christopher P and Albrecht, Eva and Mangino, Massimo and Deelen, Joris and Buxton, Jessica L and Hottenga, Jouke Jan and Fischer, Krista and Esko, Tonu and Surakka, Ida and Broer, Linda and Nyholt, Dale R and Mateo Leach, Irene and Salo, Perttu and Hagg, Sara and Matthews, Mary K and Palmen, Jutta and Norata, Giuseppe D and O'Reilly, Paul F and Saleheen, Danish and Amin, Najaf and Balmforth, Anthony J and Beekman, Marian and de Boer, Rudolf A and Bohringer, Stefan and Braund, Peter S and Burton, Paul R and de Craen, Anton J. M and Denniff, Matthew and Dong, Yanbin and Douroudis, Konstantinos and Dubinina, Elena and Eriksson, Johan G and Garlaschelli, Katia and Guo, Dehuang and Hartikainen, Anna-Liisa and Henders, Anjali K and Houwing-Duistermaat, Jeanine J and Kananen, Laura and Karssen, Lennart C and Kettunen, Johannes and Klopp, Norman and Lagou, Vasiliki and van Leeuwen, Elisabeth M and Madden, Pamela A and Maegi, Reedik and Verweij, Niek and van Veldhuisen, Dirk J and van Gilst, Wiek H and van der Harst, Pim and CARDIoGRAM Consortium and CARDIoGRAM consortium
Nature genetics, ISSN 1061-4036, 04/2013, Volume 45, Issue 4, pp. 422 - 427
VARIANTS | SUSCEPTIBILITY | CARDIOVASCULAR-DISEASE | ATHEROSCLEROSIS | RISK | DYSFUNCTION | STRESS | CANCER | CORONARY-ARTERY-DISEASE | FIBROBLASTS | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | Disease - genetics | Humans | Risk Factors | Genetic Loci - genetics | Male | Case-Control Studies | Telomerase - genetics | Female | Biomarkers, Tumor - genetics | Leukocytes - metabolism | Telomere - genetics | DNA polymerases | Physiological aspects | Telomeres | Genetic aspects | Research | Aging | Genetics | Gene therapy | Chromosomes | Deoxyribonucleic acid--DNA | Index Medicus | Medicin och hälsovetenskap
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2. Full Text Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues
by Brown, Andrew Anand and Viñuela, Ana and Delaneau, Olivier and Spector, Tim D and Small, Kerrin S and Dermitzakis, Emmanouil T
Nature genetics, ISSN 1061-4036, 12/2017, Volume 49, Issue 12, pp. 1747 - 1751
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Variation | Genetic Predisposition to Disease - genetics | Reproducibility of Results | Humans | Gene Expression Profiling - methods | Genotype | Chromosome Mapping | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | High-Throughput Nucleotide Sequencing - methods | Genome, Human - genetics | Quantitative Trait Loci - genetics | Genetic research | Research | Gene expression | Genetic variation | Identification and classification | Chromatin | Multiple sclerosis | Cardiovascular disease | Mapping | Genomes | Single-nucleotide polymorphism | Tissues | Ribonucleic acid--RNA | Human tissues | Gene sequencing | Datasets | Quantitative trait loci | Consortia | Genetic variance | Body mass index | Genotype & phenotype | Confidence | Genetics | Gene mapping | Arrays | Bioinformatics | Methods | Index Medicus
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3. Full Text Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins
by Buil, Alfonso and Brown, Andrew Anand and Lappalainen, Tuuli and Viñuela, Ana and Davies, Matthew N and Zheng, Hou-Feng and Richards, J Brent and Glass, Daniel and Small, Kerrin S and Durbin, Richard and Spector, Timothy D and Dermitzakis, Emmanouil T
Nature genetics, ISSN 1061-4036, 01/2015, Volume 47, Issue 1, pp. 88 - 91
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Twins, Monozygotic - genetics | Gene Expression Regulation - genetics | Gene Frequency | Humans | Transcriptome | Molecular Sequence Data | Epistasis, Genetic - genetics | Gene Expression Profiling | Gene-Environment Interaction | Twins, Dizygotic - genetics | Genetic Variation | Haplotypes - genetics | RNA, Messenger - biosynthesis | Sequence Analysis, RNA | Base Sequence | Alleles | Female | Models, Genetic | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Quantitative trait loci | Physiological aspects | Genetic aspects | Research | Gene expression | Twins | Studies | Medical research | Genotype & phenotype | Biomedical research | Genomes | Index Medicus
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4. Full Text Circulating proteomic signatures of chronological age
by Menni, Cristina and Kiddle, Steven J and Mangino, Massimo and Viñuela, Ana and Psatha, Maria and Steves, Claire and Sattlecker, Martina and Buil, Alfonso and Newhouse, Stephen and Nelson, Sally and Williams, Stephen and Voyle, Nicola and Soininen, Hilkka and Kloszewska, Iwona and Mecocci, Patrizia and Tsolaki, Magda and Vellas, Bruno and Lovestone, Simon and Spector, Tim D and Dobson, Richard and Valdes, Ana M
The journals of gerontology. Series A, Biological sciences and medical sciences, ISSN 1079-5006, 01/2014, Volume 70, Issue 7, pp. 809 - 816
Aging | Nucleotide | Early development | Aptamers | Proteomics | Blood biomarkers | Gerontology | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Nerve Tissue Proteins - blood | Carrier Proteins - blood | Eye Proteins - blood | Humans | Middle Aged | Male | United Kingdom | Biomarkers - blood | Aging - blood | Phenotype | Matrix Metalloproteinase 12 - blood | Insulin-Like Growth Factor Binding Protein 6 - blood | Aged, 80 and over | Adult | Female | Registries | Aged | Twins | Cohort Studies | Cytokines - blood | Proteins | Osteoporosis | Chronologies | Gene expression | Analysis | Dementia | Research | Structure | Blood plasma | Plasma | Genotype & phenotype | RNA-protein interactions | Biological assays | Index Medicus | Abridged Index Medicus | Original
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5. Full Text Gene expression changes with age in skin, adipose tissue, blood and brain
by Glass, Daniel and Glass, Daniel and Viñuela, Ana and Vinuela, Ana and Davies, Matthew N and Davies, Mathew N and Ramasamy, Adaikalavan and Ramasamy, Adaikalavan and Parts, Leopold and Parts, Leopold and Knowles, David and Knowles, David and Brown, Andrew A and Brown, Andrew A and Hedman, Åsa K and Hedman, Asa K and Small, Kerrin S and Small, Kerrin S and Buil, Alfonso and Buil, Alfonso and Grundberg, Elin and Grundberg, Elin and Nica, Alexandra C and Nica, Alexandra C and Meglio, Paola Di and Di Meglio, Paola and Nestle, Frank O and Nestle, Frank O and Ryten, Mina and Ryten, Mina and Durbin, Richard and Durbin, Richard and McCarthy, Mark I and McCarthy, Mark I and Deloukas, Panagiotis and Deloukas, Panagiotis and Dermitzakis, Emmanouil T and Dermitzakis, Emmanouil T and Weale, Michael E and Weale, Mike E and Bataille, Veronique and Bataille, Veronique and Spector, Tim D and Spector, Tim D and UK Brain Expression Consortium and MuTHER Consortium and MuTHER consortium and UK Brain Expression consortium and the UK Brain Expression consortium and the MuTHER consortium
Genome Biology, ISSN 1474-7596, 2013, Volume 14, Issue 7, pp. R75 - R75
Aging | Brain | Adipose | Skin | Gene expression | Microarrays | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Cell Line | Genome-Wide Association Study | Age Distribution | Skin - metabolism | Humans | Middle Aged | Databases, Genetic | Genotype | Aging - blood | Brain - metabolism | Adipose Tissue - metabolism | Aging - genetics | Gene Expression Regulation, Developmental | Aged, 80 and over | Polymorphism, Single Nucleotide - genetics | Adult | Female | Transcription, Genetic | Aged | Quantitative Trait Loci - genetics | Index Medicus | skin | adipose | Research | brain | gene expression | microarrays
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6. Full Text Time-dependent genetic effects on gene expression implicate aging processes
by Bryois, Julien and Buil, Alfonso and Ferreira, Pedro G and Panousis, Nikolaos I and Brown, Andrew A and Viñuela, Ana and Planchon, Alexandra and Bielser, Deborah and Small, Kerrin and Spector, Tim and Dermitzakis, Emmanouil T
Genome research, ISSN 1088-9051, 04/2017, Volume 27, Issue 4, pp. 545 - 552
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Aging - genetics | Twins, Monozygotic - genetics | Gene Expression Regulation, Developmental | Humans | Middle Aged | Transcriptome | Female | Aged | Twins, Dizygotic - genetics | Aging | Gene expression | Research | Index Medicus
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7. Full Text Tensor decomposition for multiple-tissue gene expression experiments
by Hore, Victoria and Viñuela, Ana and Buil, Alfonso and Knight, Julian and McCarthy, Mark I and Small, Kerrin and Marchini, Jonathan
Nature genetics, ISSN 1061-4036, 09/2016, Volume 48, Issue 9, pp. 1094 - 1100
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Lymphocytes - metabolism | Genome-Wide Association Study | Skin - metabolism | Humans | Gene Expression Regulation | United Kingdom | Gene Expression Profiling | Gene Regulatory Networks | Adipose Tissue - metabolism | Phenotype | Genetic Markers - genetics | Bayes Theorem | Polymorphism, Single Nucleotide - genetics | Quantitative Trait Loci | Cohort Studies | Bayesian statistical decision theory | Genome-wide association studies | Genetic variation | Gene expression | Observations | Identification and classification | Methods | Datasets | Studies | Consortia | Sparsity | Decomposition | Biology | Software | Genomes | Experiments | Cancer | Index Medicus
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8. Full Text Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation
by Tsaprouni, Loukia G and Yang, Tsun-Po and Bell, Jordana and Dick, Katherine J and Kanoni, Stavroula and Nisbet, James and Viñuela, Ana and Grundberg, Elin and Nelson, Christopher P and Meduri, Eshwar and Buil, Alfonso and Cambien, Francois and Hengstenberg, Christian and Erdmann, Jeanette and Schunkert, Heribert and Goodall, Alison H and Ouwehand, Willem H and Dermitzakis, Emmanouil and Spector, Tim D and Samani, Nilesh J and Deloukas, Panos
Epigenetics, ISSN 1559-2294, 10/2014, Volume 9, Issue 10, pp. 1382 - 1396
CHRND | epigenome-wide screen | smoking | DNA methylation | CPOX | gene network | rs2697768 | metQTLs | Gene network | Epigenome-wide screen | Smoking | Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Smoking - adverse effects | Genome-Wide Association Study | Epigenesis, Genetic | Humans | Middle Aged | Linear Models | Male | DNA Methylation | Sequence Analysis, RNA | Aged, 80 and over | CpG Islands | Adult | Female | Aged | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Index Medicus
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9. Full Text An integrated epigenomic analysis for type 2 diabetes susceptibility loci in monozygotic twins
by Yuan, Wei and Xia, Yudong and Bell, Christopher G and Yet, Idil and Ferreira, Teresa and Ward, Kirsten J and Gao, Fei and Loomis, A. Katrina and Hyde, Craig L and Wu, Honglong and Lu, Hanlin and Liu, Yuan and Small, Kerrin S and Viñuela, Ana and Morris, Andrew P and Berdasco, María and Esteller, Manel and Brosnan, M. Julia and Deloukas, Panos and McCarthy, Mark I and John, Sally L and Bell, Jordana T and Wang, Jun and Spector, Tim D
Nature communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5719 - 5719
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Nerve Tissue Proteins - blood | Diabetes Mellitus, Type 2 - genetics | Epigenesis, Genetic | Humans | Protein Kinase C beta - genetics | Taurocholic Acid - blood | Genetic Loci | Insulin - blood | Case-Control Studies | DNA Methylation | Insulin - genetics | Neoplasm Proteins - genetics | Protein Kinase C beta - blood | Promoter Regions, Genetic | Genetic Predisposition to Disease | Genome-Wide Association Study | Epigenomics | Receptors, G-Protein-Coupled - blood | Caspases - genetics | Biomarkers - blood | Twins, Monozygotic | Nerve Tissue Proteins - genetics | Diabetes Mellitus, Type 2 - blood | CpG Islands | Neoplasm Proteins - blood | Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein | Receptors, G-Protein-Coupled - genetics | Caspases - blood | Genome, Human | Index Medicus | Epigenetics | Diabetes | Twins | Bessons | Diabetis | Epigenètica
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