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Revista Bioética, ISSN 1983-8034, 12/2015, Volume 23, Issue 3, pp. 456 - 467
Resumo O uso de placebo em pesquisa clínica tem sido motivo de debate nos últimos anos, sobretudo após a Associação Médica Mundial publicar, em 2002, nota de... 
MEDICAL ETHICS | ETHICS
Journal Article
Revista Bioética, ISSN 1983-8034, Volume 23, Issue 3, pp. 456 - 467
Resumo O uso de placebo em pesquisa clínica tem sido motivo de debate nos últimos anos, sobretudo após a Associação Médica Mundial publicar, em 2002, nota de... 
Control groups | Decision support techniques | Biomedical research | Placebos | Bioethics | Helsinki Declaration | Methods
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 5, pp. 583 - 594
Journal Article
Pesquisa Agropecuaria Brasileira, ISSN 0100-204X, 08/2007, Volume 42, Issue 8, pp. 1101 - 1110
O objetivo deste trabalho foi avaliar a variabilidade espacial e temporal da produtividade de soja, milho e trigo, em uma lavoura comercial de 57 ha, não... 
Precision agriculture | Zea mays | Oxisol | Glycine max | Yield mapping | Triticum aestivum | AGRICULTURE, DAIRY & ANIMAL SCIENCE | AGRICULTURE, MULTIDISCIPLINARY | precision agriculture | mapeamento da produtividade | yield mapping | agricultura de precisão | Latossolo
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, pp. e0144333 - e0144333
Objective To evaluate the relationship between the expression profiles of 84 extracellular matrix (ECM) genes and the prognosis of patients with colorectal... 
MIGRATION | OVEREXPRESSION | OSTEOPONTIN | ACTIVATION | TUMOR PROGRESSION | MULTIDISCIPLINARY SCIENCES | METASTASES | FIBRONECTIN | EXTRACELLULAR-MATRIX | COLON-CARCINOMA CELLS | PREDICTION | Prognosis | Colorectal Neoplasms - genetics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Gene Expression Profiling | Biomarkers, Tumor | Neoplasm Metastasis | Neoplasm Grading | Adult | Female | Integrin alphaV - genetics | Colorectal Neoplasms - metabolism | Extracellular Matrix Proteins - metabolism | Integrin alphaV - metabolism | Colorectal Neoplasms - mortality | Integrin alpha3 - genetics | Extracellular Matrix Proteins - genetics | Kaplan-Meier Estimate | Proportional Hazards Models | Integrin alpha6 - genetics | Integrin alpha6 - metabolism | Aged | Colorectal Neoplasms - pathology | Neoplasm Staging | Immunohistochemistry | Genetic markers | Care and treatment | Analysis | Colorectal cancer | Research | Diagnosis | Risk factors | Integrins | Colorectal carcinoma | Science | Scoring | Metastasis | Matrix methods | Cell adhesion & migration | Confidence intervals | Regression models | Cell growth | Mathematical analysis | Surgery | Osteonectin | Extracellular matrix | Mathematical models | Statistical analysis | Markers | Regression analysis | Interdisciplinary aspects | Risk analysis | Gene expression | Survival | Patients | Gelatinase B | Medical prognosis | Tumors | Cancer | Index Medicus
Journal Article
Oncology, ISSN 0030-2414, 12/2012, Volume 84, Issue 2, pp. 81 - 91
Objective: To evaluate the relationship between the expression of the extracellular matrix (ECM) genes SPARC, SPP1, FN1, ITGA5 and ITGAV and the... 
Clinical Translational Research | Integrin | Colorectal carcinoma | Osteonectin | Biomarkers | Osteopontin | Extracellular matrix | Carcinogenesis | Fibronectin | PROMOTER HYPERMETHYLATION | METASTASIS | MICROARRAY | MARKER | COLON-CANCER | GROWTH-FACTOR RECEPTOR | ADHESION | INVASION | ONCOLOGY | INTEGRINS | Adenocarcinoma - pathology | Follow-Up Studies | Colorectal Neoplasms - genetics | Humans | Lung Neoplasms - metabolism | Middle Aged | Male | Immunoenzyme Techniques | Ovarian Neoplasms - genetics | Young Adult | Ovarian Neoplasms - secondary | Adenocarcinoma - metabolism | Aged, 80 and over | Biomarkers, Tumor - metabolism | Ovarian Neoplasms - metabolism | Liver Neoplasms - secondary | Real-Time Polymerase Chain Reaction | Integrin alphaV - metabolism | Tumor Suppressor Proteins - metabolism | Liver Neoplasms - genetics | Lymphatic Metastasis | Reverse Transcriptase Polymerase Chain Reaction | Peritoneal Neoplasms - metabolism | Liver Neoplasms - metabolism | Biomarkers, Tumor - genetics | Integrin alpha5 - genetics | Osteopontin - genetics | Prognosis | Tissue Array Analysis | Osteopontin - metabolism | Lung Neoplasms - secondary | Tumor Suppressor Proteins - genetics | Adult | Female | Adenocarcinoma - genetics | Integrin alphaV - genetics | Colorectal Neoplasms - metabolism | Peritoneal Neoplasms - secondary | Lung Neoplasms - genetics | Neoplasm Invasiveness | RNA, Messenger - genetics | Fibronectins - metabolism | Peritoneal Neoplasms - genetics | Integrin alpha5 - metabolism | Aged | Fibronectins - genetics | Colorectal Neoplasms - pathology | Neoplasm Staging | Oncology | Cellular biology | Gene expression | Colorectal cancer | Tumors | Index Medicus
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 01/2019, Volume 20, Issue 1, pp. 91 - 96
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 4091 - 4091
Journal Article
ONCOTARGET, ISSN 1949-2553, 08/2017, Volume 8, Issue 32, pp. 53288 - 53301
Epidermal growth factor receptor (EGFR) is overexpressed in up to 90% of head and neck squamous cell carcinoma (HNSCC) tumors. Cetuximab is the first targeted... 
HEAD | PLUS CETUXIMAB | MECHANISMS | resistance | NECK-CANCER | CELL BIOLOGY | anti-EGFR | anti-AKT | GROWTH-FACTOR RECEPTOR | THERAPY | HNSCC | COLORECTAL-CANCER | COPY NUMBER | AKT1 | MUTATIONS | CARCINOMA
Journal Article
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 3209 - 10
Lung cancer is the deadliest cancer worldwide. The mutational frequency of EGFR and KRAS genes in lung adenocarcinoma varies worldwide per ethnicity and... 
TYROSINE KINASE INHIBITORS | RECEPTOR GENE-MUTATIONS | SURVIVAL | GEFITINIB | MANAGEMENT | COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | RESISTANCE | CLASSIFICATION | INFERENCE | SOCIETY | Adenocarcinoma | Tobacco | Epidermal growth factor receptors | Lung | Lung cancer | Mutation | Minority & ethnic groups | Smoking
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 6, pp. 9911 - 9921
Despite progress in the treatment of head and neck squamous cell carcinoma (HNSCC) in recent decades, including new surgical techniques, radiotherapy advances... 
Chemoradiation | HNSCC | MicroRNA | BLADDER-CANCER | RNA FRAGMENTS | PROLIFERATION | DIAGNOSTIC BIOMARKERS | MICRORNAS | CELL BIOLOGY | BREAST-CANCER | IN-VITRO | MIR-494 | COLORECTAL-CANCER | microRNA | chemoradiation | EXPRESSION | Multivariate Analysis | Predictive Value of Tests | Chemoradiotherapy - adverse effects | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Chemoradiotherapy - mortality | Male | Gene Expression Profiling | Laryngeal Neoplasms - pathology | Patient Selection | Organ Sparing Treatments - methods | Laryngeal Neoplasms - therapy | Squamous Cell Carcinoma of Head and Neck | Carcinoma, Squamous Cell - mortality | Time Factors | Organ Sparing Treatments - adverse effects | Female | Odds Ratio | Precision Medicine | Laryngeal Neoplasms - genetics | Reproducibility of Results | Risk Factors | Head and Neck Neoplasms - therapy | Proportional Hazards Models | Carcinoma, Squamous Cell - therapy | Pharyngeal Neoplasms - therapy | Treatment Outcome | Chi-Square Distribution | Disease Progression | Pharyngeal Neoplasms - mortality | Head and Neck Neoplasms - pathology | Disease-Free Survival | Pharyngeal Neoplasms - genetics | Laryngeal Neoplasms - mortality | Head and Neck Neoplasms - genetics | Pharyngeal Neoplasms - pathology | Biomarkers, Tumor - genetics | MicroRNAs - genetics | Head and Neck Neoplasms - mortality | Organ Sparing Treatments - mortality | Index Medicus
Journal Article
Journal Article