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Human Mutation, ISSN 1059-7794, 07/2017, Volume 38, Issue 7, pp. 749 - 749
Journal Article
by Francioli, Laurent C and Menelaou, Anoniki and Pulit, Sara L and van Dijk, Freerk and Palamara, Pier Francesco and Elbers, Clara C and Neerincx, Pieter B. T and Ye, Kai and Guryev, Victor and Kloosterman, Wigard P and Deelen, Patrick and Abdellaoui, Abdel and van Leeuwen, Elisabeth M and van Oven, Mannis and Vermaat, Martijn and Li, Mingkun and Laros, Jeroen F. J and Karssen, Lennart C and Kanterakis, Alexanos and Amin, Najaf and Hottenga, Jouke Jan and Lameijer, Eric-Wubbo and Kattenberg, Mathijs and Dijkstra, Martijn and Byelas, Heorhiy and van Setten, Jessica and van Schaik, Barbera D. C and Bot, Jan and Nijman, Isaäc J and Renkens, Ivo and Marschall, Tobias and Schönhuth, Alexander and Hehir-Kwa, Jayne Y and Handsaker, Robert E and Polak, Paz and Sohail, Mashaal and Vuzman, Dana and Hormozdiari, Fereydoun and van Enckevort, David and Mei, Hailiang and Koval, Vyacheslav and Moed, Matthijs H and van der Velde, K. Joeri and Rivadeneira, Fernando and Estrada, Karol and Medina-Gomez, Carolina and Isaacs, Aaron and McCarroll, Steven A and Beekman, Marian and de Craen, Anton J. M and Suchiman, H. Eka D and Hofman, Albert and Oostra, Ben and Uitterlinden, Ané G and Willemsen, Gonneke and Platteel, Mathieu and Veldink, Jan H and van den Berg, Leonard H and Pitts, Steven J and Potluri, Shobha and Sundar, Purnima and Cox, David R and Sunyaev, Shamil R and den Dunnen, Johan T and Stoneking, Mark and de Knijff, Peter and Kayser, Manfred and Li, Qibin and Li, Yingrui and Du, Yuanping and Chen, Ruoyan and Cao, Hongzhi and Li, Ning and Cao, Sujie and Wang, Jun and Bovenberg, Jasper A and Pe'er, Itsik and Slagboom, P. Eline and van Duijn, Cornelia M and Boomsma, Dorret I and van Ommen, Gert-Jan B and de Bakker, Paul I. W and Swertz, Morris A and Wijmenga, Cisca and LifeLines Cohort Study and Genome Netherlands Consortium and Genome of the Netherlands Consortium and The Genome of the Netherlands Consortium
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 8, pp. 818 - 825
Journal Article
Briefings in Bioinformatics, ISSN 1467-5463, 10/2016
Many disciplines, from human genetics and oncology to plant breeding, microbiology and virology, commonly face the challenge of analyzing rapidly increasing... 
Journal Article
Current Biology, ISSN 0960-9822, 09/2017, Volume 27, Issue 17, pp. 2652 - 2660.e4
Cellular senescence is a state of irreversibly arrested proliferation, often induced by genotoxic stress [ ]. Senescent cells participate in a variety of... 
tumor suppression | whole-transcriptome sequencing | cell-cycle arrest | cellular senescence | RNA-seq | DNA damage | primary cells | qPCR | transcriptional signatures | SASP | ROLES | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION PROFILES | MECHANISMS | CELLULAR SENESCENCE | P53 | CELL BIOLOGY | Embryonic development | Genetic aspects | Genetic transcription | RNA | DNA repair | Genes | Index Medicus
Journal Article
PHYSIOLOGICAL GENOMICS, ISSN 1094-8341, 05/2019, Volume 51, Issue 5, pp. 145 - 158
Transcriptome sequencing is a powerful technique to study molecular changes that underlie the differences in physiological conditions and disease progression.... 
METHYLATION | PHYSIOLOGY | MESSENGER-RNA SYNTHESIS | DETERMINANTS | BEHAVIOR | gene expression variability | NOISE | gene noise | CELL BIOLOGY | SPEED | MODELS | RNA-Seq | GENETICS & HEREDITY | STOCHASTICITY | GAMLSS | VARIANCE | gene expression | REVEALS | Aging | Phenotypes | Physiology | Gene expression
Journal Article
Aging Cell, ISSN 1474-9718, 06/2018, Volume 17, Issue 3, pp. e12739 - n/a
Animals show a large variability of lifespan, ranging from short‐lived as Caenorhabditis elegans to immortal as Hydra . A fascinating case is flatworms, in... 
stem cells | aging | rejuvenation | flatworms | regeneration | gene expression | LIFE-SPAN | CAPACITY | OXYGEN-CONSUMPTION | STEM-CELLS | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | MAINTENANCE | METABOLISM | STARVATION | AGE | Gene expression | Analysis | Genes | Stem cells | Hypotheses | Life span | Aging | Stem cell transplantation | Exploration | Original
Journal Article