Journal of Translational Medicine, ISSN 1479-5876, 10/2012, Volume 10, Issue 1, pp. 205 - 205
Prediction of clinical outcome in cancer is usually achieved by histopathological evaluation of tissue samples obtained during surgical resection of the...
MEDICINE, RESEARCH & EXPERIMENTAL | T-CELL SUBSETS | IMMUNE CELLS | TUMOR-MARKERS | MICROENVIRONMENT | RECOMMENDATIONS | COLORECTAL-CANCER | MICROSATELLITE INSTABILITY | BIOMARKER DISCOVERY | MOLECULAR-ORIGINS | CHEMOTHERAPY | Neoplasms - therapy | Internationality | Neoplasms - immunology | Humans | Tumor Microenvironment | Classification - methods | Neoplasms - classification | Treatment Outcome | Advisory Committees | Task forces | Analysis | Tumor staging | Development and progression | B cells | Metastasis | Cancer | Life Sciences | Human health and pathology | Medical and Health Sciences | Medicin och hälsovetenskap
MEDICINE, RESEARCH & EXPERIMENTAL | T-CELL SUBSETS | IMMUNE CELLS | TUMOR-MARKERS | MICROENVIRONMENT | RECOMMENDATIONS | COLORECTAL-CANCER | MICROSATELLITE INSTABILITY | BIOMARKER DISCOVERY | MOLECULAR-ORIGINS | CHEMOTHERAPY | Neoplasms - therapy | Internationality | Neoplasms - immunology | Humans | Tumor Microenvironment | Classification - methods | Neoplasms - classification | Treatment Outcome | Advisory Committees | Task forces | Analysis | Tumor staging | Development and progression | B cells | Metastasis | Cancer | Life Sciences | Human health and pathology | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
2.
Full Text
Towards the introduction of the 'Immunoscore' in the classification of malignant tumours
Journal of Pathology, ISSN 0022-3417, 2014, Volume 232, Issue 2, pp. 199 - 209
The American Joint Committee on Cancer/Union Internationale Contre le Cancer (AJCC/UICC) TNM staging system provides the most reliable guidelines for the...
colon carcinoma | colorectal cancer | prognostic markers | immune response | Immunoscore | predictive markers | tumour microenvironment | classification | T cells | SURVIVAL | POPULATION | T-CELL SUBSETS | IMMUNE CELLS | MICROSATELLITE INSTABILITY | INFILTRATING LYMPHOCYTES | PATHOLOGY | ISLAND METHYLATOR PHENOTYPE | PROGNOSTIC-FACTOR | ONCOLOGY | CLINICAL IMPACT | COLORECTAL-CANCER | Tumor Microenvironment - immunology | Predictive Value of Tests | Biomarkers, Tumor - analysis | Neoplasms - immunology | Humans | Immunophenotyping - methods | Neoplasms - classification | Neoplasm Staging | Neoplasms - pathology | Analysis | Colorectal cancer | Tumors | Invited Reviews | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Clinical Medicine | Cancer and Oncology | Cancer och onkologi
colon carcinoma | colorectal cancer | prognostic markers | immune response | Immunoscore | predictive markers | tumour microenvironment | classification | T cells | SURVIVAL | POPULATION | T-CELL SUBSETS | IMMUNE CELLS | MICROSATELLITE INSTABILITY | INFILTRATING LYMPHOCYTES | PATHOLOGY | ISLAND METHYLATOR PHENOTYPE | PROGNOSTIC-FACTOR | ONCOLOGY | CLINICAL IMPACT | COLORECTAL-CANCER | Tumor Microenvironment - immunology | Predictive Value of Tests | Biomarkers, Tumor - analysis | Neoplasms - immunology | Humans | Immunophenotyping - methods | Neoplasms - classification | Neoplasm Staging | Neoplasms - pathology | Analysis | Colorectal cancer | Tumors | Invited Reviews | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Clinical Medicine | Cancer and Oncology | Cancer och onkologi
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2013, Volume 56, Issue 3, pp. 735 - 747
The integrin leukocyte function associated antigen 1 (LFA-1) binds the intercellular adhesion molecule 1 (ICAM-1) by its αL-chain inserted domain (I-domain)....
I-LIKE DOMAIN | CHEMISTRY, MEDICINAL | INTERCELLULAR-ADHESION MOLECULE-1 | INTEGRIN ALPHA-L-BETA-2 | ALPHA | DISULFIDE BOND | ICAM-1 | CONFORMATION | ALLOSTERIC SITE | BINDING | ENDOTHELIAL GROWTH-FACTOR | Humans | Drug Design | Cell Line, Tumor | Models, Molecular | Lymphocyte Function-Associated Antigen-1 - drug effects | Structure-Activity Relationship | Neoplasms - physiopathology
I-LIKE DOMAIN | CHEMISTRY, MEDICINAL | INTERCELLULAR-ADHESION MOLECULE-1 | INTEGRIN ALPHA-L-BETA-2 | ALPHA | DISULFIDE BOND | ICAM-1 | CONFORMATION | ALLOSTERIC SITE | BINDING | ENDOTHELIAL GROWTH-FACTOR | Humans | Drug Design | Cell Line, Tumor | Models, Molecular | Lymphocyte Function-Associated Antigen-1 - drug effects | Structure-Activity Relationship | Neoplasms - physiopathology
Journal Article
EXPERIMENTAL CELL RESEARCH, ISSN 0014-4827, 02/2013, Volume 319, Issue 3, pp. 12 - 22
Colorectal cancer (CRC) frequently metastasizes to the liver, a phenomenon that involves the participation of transforming-growth-factor-beta(1) (TGF beta(1))....
SMAD4 | Metastasis | CELL BIOLOGY | TGF-beta | INVASION | Colon cancer | ONCOLOGY | HUMAN GLIOBLASTOMA | COLORECTAL-CANCER | BONE METASTASIS | INHIBITORS | Cancer stem cells | CARCINOMA | PROGRESSION | GROWTH-FACTOR BETA-1
SMAD4 | Metastasis | CELL BIOLOGY | TGF-beta | INVASION | Colon cancer | ONCOLOGY | HUMAN GLIOBLASTOMA | COLORECTAL-CANCER | BONE METASTASIS | INHIBITORS | Cancer stem cells | CARCINOMA | PROGRESSION | GROWTH-FACTOR BETA-1
Journal Article
Cell and Tissue Research, ISSN 0302-766X, 10/2017, Volume 370, Issue 1, pp. 29 - 39
Colorectal cancer (CRC) is one of the most frequent tumor types in Western countries. Approximately 20 % of patients show metastasis at the time of diagnosis,...
Human Genetics | Epithelial to mesenchymal transition | TGF-beta | Biomedicine | Colon cancer | Proteomics | Molecular Medicine | Metastasis | Cancer stem cells | CELLS | TUMOR SUPPRESSION | LIVER METASTASIS | I-RECEPTOR | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | SIGNALING PATHWAY | COLORECTAL-CANCER | MICE | INHIBITOR | GROWTH-FACTOR BETA-1 | Medical research | Mesenchyme | Liver | Transforming growth factor-b | Colorectal carcinoma | Transforming growth factor-a | Organs | Colorectal cancer | Clinical trials | Stroma | Cancer therapies | Metastases | Industrial development | Molecular modelling | Colon | Pharmaceutical industry | Cancer
Human Genetics | Epithelial to mesenchymal transition | TGF-beta | Biomedicine | Colon cancer | Proteomics | Molecular Medicine | Metastasis | Cancer stem cells | CELLS | TUMOR SUPPRESSION | LIVER METASTASIS | I-RECEPTOR | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | SIGNALING PATHWAY | COLORECTAL-CANCER | MICE | INHIBITOR | GROWTH-FACTOR BETA-1 | Medical research | Mesenchyme | Liver | Transforming growth factor-b | Colorectal carcinoma | Transforming growth factor-a | Organs | Colorectal cancer | Clinical trials | Stroma | Cancer therapies | Metastases | Industrial development | Molecular modelling | Colon | Pharmaceutical industry | Cancer
Journal Article
Archives of Medical Research, ISSN 0188-4409, 02/2019, Volume 50, Issue 2, pp. 20 - 28
Metabolic syndrome (MetS) is a heterogeneous clinical entity associated with insulin resistance, low-grade proinflammatory balance and impaired endothelial...
PAI-1 | Omentin-1 | Metabolic syndrome | Soluble ICAM-1 | Soluble VCAM-1 | Atherosclerosis | HIGH-RISK PLAQUE | MEDICINE, RESEARCH & EXPERIMENTAL | INTERCELLULAR-ADHESION MOLECULE-1 | CAROTID ATHEROSCLEROSIS | CORONARY | ADULTS | PREVALENCE | ULTRASOUND | INSULIN-RESISTANCE | CARDIOVASCULAR-DISEASE | AMERICAN SOCIETY | Medicine, Experimental | Medical research | Insulin resistance | Smokers | Endothelium
PAI-1 | Omentin-1 | Metabolic syndrome | Soluble ICAM-1 | Soluble VCAM-1 | Atherosclerosis | HIGH-RISK PLAQUE | MEDICINE, RESEARCH & EXPERIMENTAL | INTERCELLULAR-ADHESION MOLECULE-1 | CAROTID ATHEROSCLEROSIS | CORONARY | ADULTS | PREVALENCE | ULTRASOUND | INSULIN-RESISTANCE | CARDIOVASCULAR-DISEASE | AMERICAN SOCIETY | Medicine, Experimental | Medical research | Insulin resistance | Smokers | Endothelium
Journal Article
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Towards the introduction of the 'Immunoscore' in the classification of malignant tumours
The Journal of pathology, ISSN 1096-9896, 2014, Volume 232, Issue 2, p. 199
Journal Article
Gut, ISSN 0017-5749, 10/2012, Volume 61, Issue 10, pp. 1465 - 1472
Background The transdifferentiation of hepatic stellate cells (HSCs) into myofibroblasts is a major mechanism for stroma development in hepatic metastasis, but...
CELL-ADHESION MOLECULE-1 | HEPATOCELLULAR-CARCINOMA | TGF-BETA | SINUSOIDAL ENDOTHELIUM | MANNOSE RECEPTOR | LIVER | EXPERIMENTAL MELANOMA METASTASIS | STELLATE CELLS | FACTOR-I | GASTROENTEROLOGY & HEPATOLOGY | ENDOTHELIAL GROWTH-FACTOR | Liver Neoplasms, Experimental - secondary | Myofibroblasts - pathology | Receptor Protein-Tyrosine Kinases - deficiency | Oligonucleotide Array Sequence Analysis | Biomarkers, Tumor - deficiency | Male | Reverse Transcriptase Polymerase Chain Reaction | Cell Transformation, Neoplastic - metabolism | Mice, Knockout | Liver Neoplasms, Experimental - metabolism | Discoidin Domain Receptors | Animals | Colonic Neoplasms - pathology | Cell Line, Tumor | Mice | Hepatic Stellate Cells - pathology | Receptors, Mitogen - deficiency | Protein tyrosine kinase | Physiological aspects | Development and progression | Colon cancer | Research | Metastasis
CELL-ADHESION MOLECULE-1 | HEPATOCELLULAR-CARCINOMA | TGF-BETA | SINUSOIDAL ENDOTHELIUM | MANNOSE RECEPTOR | LIVER | EXPERIMENTAL MELANOMA METASTASIS | STELLATE CELLS | FACTOR-I | GASTROENTEROLOGY & HEPATOLOGY | ENDOTHELIAL GROWTH-FACTOR | Liver Neoplasms, Experimental - secondary | Myofibroblasts - pathology | Receptor Protein-Tyrosine Kinases - deficiency | Oligonucleotide Array Sequence Analysis | Biomarkers, Tumor - deficiency | Male | Reverse Transcriptase Polymerase Chain Reaction | Cell Transformation, Neoplastic - metabolism | Mice, Knockout | Liver Neoplasms, Experimental - metabolism | Discoidin Domain Receptors | Animals | Colonic Neoplasms - pathology | Cell Line, Tumor | Mice | Hepatic Stellate Cells - pathology | Receptors, Mitogen - deficiency | Protein tyrosine kinase | Physiological aspects | Development and progression | Colon cancer | Research | Metastasis
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 09/2012, Volume 104, Issue 17, pp. 1306 - 1319
Previous studies identified the human nonmetastatic gene 23 (NME1, hereafter Nm23-H1) as the first metastasis suppressor gene. An inverse relationship between...
SIGNAL-TRANSDUCTION | GREEN FLUORESCENT PROTEIN | IN-VITRO | ONCOLOGY | SUPPRESSOR PROTEINS | CARCINOMA-CELL-LINE | KINASE ALPHA-ISOFORM | PROTEIN-COUPLED RECEPTORS | ADENOCARCINOMA CELLS | TUMOR-GROWTH | DIPHOSPHATE KINASE | Immunohistochemistry | Propionates - pharmacology | Gene Expression Regulation, Enzymologic - drug effects | eIF-2 Kinase - metabolism | Lung Neoplasms - metabolism | Ki-67 Antigen - metabolism | Receptors, Lysophosphatidic Acid - genetics | Mammary Neoplasms, Experimental - metabolism | eIF-2 Kinase - drug effects | NM23 Nucleoside Diphosphate Kinases - metabolism | Lung Neoplasms - secondary | Mammary Neoplasms, Experimental - pathology | NM23 Nucleoside Diphosphate Kinases - drug effects | Female | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Receptors, Lysophosphatidic Acid - antagonists & inhibitors | Liver Neoplasms - secondary | Mammary Neoplasms, Experimental - drug therapy | Liver Neoplasms - prevention & control | RNA, Small Interfering - pharmacology | Random Allocation | Blotting, Western | Isoxazoles - pharmacology | Animals | MAP Kinase Signaling System - drug effects | Analysis of Variance | Lung Neoplasms - prevention & control | Mice, Nude | Liver Neoplasms - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Ki-67 Antigen - drug effects | Animal experimentation | Care and treatment | Usage | Analysis | Physiological aspects | Genetic aspects | Breast cancer | Metastasis | Gene expression
SIGNAL-TRANSDUCTION | GREEN FLUORESCENT PROTEIN | IN-VITRO | ONCOLOGY | SUPPRESSOR PROTEINS | CARCINOMA-CELL-LINE | KINASE ALPHA-ISOFORM | PROTEIN-COUPLED RECEPTORS | ADENOCARCINOMA CELLS | TUMOR-GROWTH | DIPHOSPHATE KINASE | Immunohistochemistry | Propionates - pharmacology | Gene Expression Regulation, Enzymologic - drug effects | eIF-2 Kinase - metabolism | Lung Neoplasms - metabolism | Ki-67 Antigen - metabolism | Receptors, Lysophosphatidic Acid - genetics | Mammary Neoplasms, Experimental - metabolism | eIF-2 Kinase - drug effects | NM23 Nucleoside Diphosphate Kinases - metabolism | Lung Neoplasms - secondary | Mammary Neoplasms, Experimental - pathology | NM23 Nucleoside Diphosphate Kinases - drug effects | Female | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Receptors, Lysophosphatidic Acid - antagonists & inhibitors | Liver Neoplasms - secondary | Mammary Neoplasms, Experimental - drug therapy | Liver Neoplasms - prevention & control | RNA, Small Interfering - pharmacology | Random Allocation | Blotting, Western | Isoxazoles - pharmacology | Animals | MAP Kinase Signaling System - drug effects | Analysis of Variance | Lung Neoplasms - prevention & control | Mice, Nude | Liver Neoplasms - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Ki-67 Antigen - drug effects | Animal experimentation | Care and treatment | Usage | Analysis | Physiological aspects | Genetic aspects | Breast cancer | Metastasis | Gene expression
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 11/2011, Volume 10, Issue Supplement 1, pp. B96 - B96
Journal Article
JOURNAL OF TRANSLATIONAL MEDICINE, ISSN 1479-5876, 06/2013, Volume 11, Issue 1, pp. 137 - 137
Recent insights into the genetic and somatic aberrations have initiated a new era of rapidly evolving targeted and immune-based treatments for melanoma. After...
HIGH-RISK MELANOMA | MEDICINE, RESEARCH & EXPERIMENTAL | METASTATIC MELANOMA | PREDICTIVE MARKER | SENTINEL LYMPH-NODES | BRAF(V600E) INHIBITION | SIGNALING PATHWAY | ADJUVANT INTERFERON THERAPY | PERIPHERAL-BLOOD | PEGYLATED INTERFERON-ALPHA-2B | ANTITUMOR-ACTIVITY | Melanoma - metabolism | Melanoma - diagnosis | Prognosis | Skin Neoplasms - therapy | Humans | Gene Expression Regulation, Neoplastic | Antineoplastic Agents - therapeutic use | Clinical Trials as Topic | Biomarkers, Tumor | Animals | Medical Oncology - trends | Skin Neoplasms - diagnosis | Mutation | Melanoma - therapy | Viral antibodies | Medical research | Care and treatment | Melanoma | Medicine, Experimental | Antibodies | Pharmaceutical industry | Biotechnology industry | Cancer | Hospitals | Life Sciences | Human health and pathology
HIGH-RISK MELANOMA | MEDICINE, RESEARCH & EXPERIMENTAL | METASTATIC MELANOMA | PREDICTIVE MARKER | SENTINEL LYMPH-NODES | BRAF(V600E) INHIBITION | SIGNALING PATHWAY | ADJUVANT INTERFERON THERAPY | PERIPHERAL-BLOOD | PEGYLATED INTERFERON-ALPHA-2B | ANTITUMOR-ACTIVITY | Melanoma - metabolism | Melanoma - diagnosis | Prognosis | Skin Neoplasms - therapy | Humans | Gene Expression Regulation, Neoplastic | Antineoplastic Agents - therapeutic use | Clinical Trials as Topic | Biomarkers, Tumor | Animals | Medical Oncology - trends | Skin Neoplasms - diagnosis | Mutation | Melanoma - therapy | Viral antibodies | Medical research | Care and treatment | Melanoma | Medicine, Experimental | Antibodies | Pharmaceutical industry | Biotechnology industry | Cancer | Hospitals | Life Sciences | Human health and pathology
Journal Article
PLOS ONE, ISSN 1932-6203, 09/2010, Volume 5, Issue 9
Background: Cell surface sialylation is emerging as an important feature of cancer cell metastasis. Sialyltransferase expression has been reported to be...
BREAST-CANCER | NATURAL-KILLER-CELLS | FUCOSYL-TRANSFERASE | MESSENGER-RNA EXPRESSION | BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE | SINUSOIDAL ENDOTHELIAL-CELLS | MULTIDISCIPLINARY SCIENCES | HUMAN HEPATOCARCINOMA | TUMOR-CELLS | SIALYL-LEWIS-X | HUMAN COLORECTAL-CANCER
BREAST-CANCER | NATURAL-KILLER-CELLS | FUCOSYL-TRANSFERASE | MESSENGER-RNA EXPRESSION | BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE | SINUSOIDAL ENDOTHELIAL-CELLS | MULTIDISCIPLINARY SCIENCES | HUMAN HEPATOCARCINOMA | TUMOR-CELLS | SIALYL-LEWIS-X | HUMAN COLORECTAL-CANCER
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2013, Volume 183, Issue 1, pp. 69 - 82
IL-18 is an immune-stimulating cytokine that promotes experimental melanoma metastasis via vascular endothelial growth factor (VEGF)–induced very late antigen...
Pathology | CELL-ADHESION MOLECULE-1 | DIFFERENTIAL EXPRESSION | SINUSOIDAL ENDOTHELIUM | INDUCED APOPTOSIS | COLORECTAL-CANCER | TUMOR-METASTASIS | GROWTH | RECEPTOR | PATHOLOGY | PROGRESSION | HUMAN-MALIGNANT MELANOMA | Integrin alpha4beta1 - metabolism | Oligonucleotide Array Sequence Analysis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Gene Expression Profiling | Vascular Endothelial Growth Factor A - metabolism | Flow Cytometry | Melanoma - genetics | Biomarkers, Tumor - metabolism | Female | Liver Neoplasms - secondary | Melanoma - metabolism | Skin Neoplasms - pathology | Enzyme-Linked Immunosorbent Assay | Liver Neoplasms - genetics | Lymphatic Metastasis | Melanoma - pathology | Reverse Transcriptase Polymerase Chain Reaction | Melanoma - secondary | Skin Neoplasms - metabolism | Phenotype | Animals | Mice, Nude | Skin Neoplasms - genetics | Liver Neoplasms - metabolism | Skin Neoplasms - secondary | Cell Line, Tumor | Biomarkers, Tumor - genetics | Mice | Neoplasm Staging | Interleukin-18 - metabolism | Cluster Analysis | DNA, Complementary
Pathology | CELL-ADHESION MOLECULE-1 | DIFFERENTIAL EXPRESSION | SINUSOIDAL ENDOTHELIUM | INDUCED APOPTOSIS | COLORECTAL-CANCER | TUMOR-METASTASIS | GROWTH | RECEPTOR | PATHOLOGY | PROGRESSION | HUMAN-MALIGNANT MELANOMA | Integrin alpha4beta1 - metabolism | Oligonucleotide Array Sequence Analysis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Gene Expression Profiling | Vascular Endothelial Growth Factor A - metabolism | Flow Cytometry | Melanoma - genetics | Biomarkers, Tumor - metabolism | Female | Liver Neoplasms - secondary | Melanoma - metabolism | Skin Neoplasms - pathology | Enzyme-Linked Immunosorbent Assay | Liver Neoplasms - genetics | Lymphatic Metastasis | Melanoma - pathology | Reverse Transcriptase Polymerase Chain Reaction | Melanoma - secondary | Skin Neoplasms - metabolism | Phenotype | Animals | Mice, Nude | Skin Neoplasms - genetics | Liver Neoplasms - metabolism | Skin Neoplasms - secondary | Cell Line, Tumor | Biomarkers, Tumor - genetics | Mice | Neoplasm Staging | Interleukin-18 - metabolism | Cluster Analysis | DNA, Complementary
Journal Article
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, ISSN 1357-2725, 08/2013, Volume 45, Issue 8, pp. 1748 - 1757
Sialyltransferases have received much attention recently as they are frequently up-regulated in cancer cells. However, the role played by each...
Sialyl-Lewis(x) | CANCER-CELLS | SUBSTRATE SPECIFICITIES | Migration | BIOCHEMISTRY & MOLECULAR BIOLOGY | Metastasis | SIALYL-LEWIS-X | SIALYLTRANSFERASE FAMILY | CELL BIOLOGY | HUMAN ALPHA(1,3)FUCOSYLTRANSFERASE GENE | COLORECTAL-CANCER | GASTRIC-CARCINOMA | ACCEPTOR SPECIFICITY | Pancreatic adenocarcinoma | MOLECULAR-CLONING | COLON ADENOCARCINOMA | alpha 2,3-Sialyltransferases | Biotechnology | Progressions | Tumours | Biochemistry | Biology | Survival | Adhesion
Sialyl-Lewis(x) | CANCER-CELLS | SUBSTRATE SPECIFICITIES | Migration | BIOCHEMISTRY & MOLECULAR BIOLOGY | Metastasis | SIALYL-LEWIS-X | SIALYLTRANSFERASE FAMILY | CELL BIOLOGY | HUMAN ALPHA(1,3)FUCOSYLTRANSFERASE GENE | COLORECTAL-CANCER | GASTRIC-CARCINOMA | ACCEPTOR SPECIFICITY | Pancreatic adenocarcinoma | MOLECULAR-CLONING | COLON ADENOCARCINOMA | alpha 2,3-Sialyltransferases | Biotechnology | Progressions | Tumours | Biochemistry | Biology | Survival | Adhesion
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2013, Volume 182, Issue 6, pp. 2368 - 2379
Brain metastases occur in more than one-third of metastatic breast cancer patients whose tumors overexpress HER2 or are triple negative. Brain colonization of...
Pathology | GROWTH-FACTOR RECEPTOR | OVEREXPRESSION | ANGIOGENESIS | PERMEABILITY | ALPHA-RECEPTOR | BARRIER | MOUSE | REACTIVE ASTROCYTES | COLONIZATION | PATHOLOGY | TUMORS | Neoplasm Transplantation | Humans | Brain Neoplasms - pathology | Tumor Microenvironment | Antineoplastic Agents - therapeutic use | Neoplasm Proteins - metabolism | Brain Neoplasms - metabolism | Breast Neoplasms - metabolism | Neuroglia - drug effects | Brain Neoplasms - secondary | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | Female | Antineoplastic Agents - pharmacology | Phosphorylation - drug effects | Tumor Cells, Cultured | Receptor, Platelet-Derived Growth Factor beta - metabolism | Astrocytes - drug effects | Drug Evaluation, Preclinical - methods | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Brain Neoplasms - prevention & control | Animals | Sulfonamides - therapeutic use | Breast Neoplasms - pathology | Pyrimidines - therapeutic use | Neuroglia - metabolism | Mice | Neoplasm Micrometastasis - pathology | Astrocytes - metabolism | Regular
Pathology | GROWTH-FACTOR RECEPTOR | OVEREXPRESSION | ANGIOGENESIS | PERMEABILITY | ALPHA-RECEPTOR | BARRIER | MOUSE | REACTIVE ASTROCYTES | COLONIZATION | PATHOLOGY | TUMORS | Neoplasm Transplantation | Humans | Brain Neoplasms - pathology | Tumor Microenvironment | Antineoplastic Agents - therapeutic use | Neoplasm Proteins - metabolism | Brain Neoplasms - metabolism | Breast Neoplasms - metabolism | Neuroglia - drug effects | Brain Neoplasms - secondary | Receptor, Platelet-Derived Growth Factor beta - antagonists & inhibitors | Female | Antineoplastic Agents - pharmacology | Phosphorylation - drug effects | Tumor Cells, Cultured | Receptor, Platelet-Derived Growth Factor beta - metabolism | Astrocytes - drug effects | Drug Evaluation, Preclinical - methods | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Brain Neoplasms - prevention & control | Animals | Sulfonamides - therapeutic use | Breast Neoplasms - pathology | Pyrimidines - therapeutic use | Neuroglia - metabolism | Mice | Neoplasm Micrometastasis - pathology | Astrocytes - metabolism | Regular
Journal Article