Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (66) 66
index medicus (64) 64
immunology (46) 46
immunoglobulin g (43) 43
animals (33) 33
mice (30) 30
biochemistry (27) 27
antibodies (26) 26
fc receptors (26) 26
chemistry (25) 25
female (25) 25
glycosylation (25) 25
hematology (25) 25
microbiology (25) 25
organic chemistry (25) 25
peptides (25) 25
beer (22) 22
enzymology (22) 22
metallurgy (22) 22
mutation or genetic engineering (22) 22
spirits (22) 22
vinegar (22) 22
wine (22) 22
compositions thereof (19) 19
culture media (19) 19
immunoglobulin g - immunology (19) 19
microorganisms or enzymes (19) 19
propagating, preserving or maintaining microorganisms (19) 19
binding (18) 18
immunoglobulin-g (17) 17
pregnancy (17) 17
abridged index medicus (16) 16
immunoglobulins (16) 16
immunoglobulin g - metabolism (15) 15
male (15) 15
antiinflammatory activity (14) 14
immunoglobulin g - chemistry (14) 14
monoclonal-antibodies (14) 14
phagocytosis (14) 14
immunoglobulin g - blood (13) 13
research (13) 13
human necessities (12) 12
hygiene (12) 12
igg (12) 12
medical or veterinary science (12) 12
physics (12) 12
preparations for medical, dental, or toilet purposes (12) 12
receptors, fc - metabolism (12) 12
autoantibodies (11) 11
crystal-structure (11) 11
investigating or analysing materials by determining theirchemical or physical properties (11) 11
measuring (11) 11
multidisciplinary sciences (11) 11
testing (11) 11
antigens (10) 10
article (10) 10
carbohydrates (10) 10
complement (10) 10
immune system (10) 10
mass spectrometry (10) 10
polysaccharides (10) 10
protein binding (10) 10
rheumatoid-arthritis (10) 10
adult (9) 9
affinity (9) 9
hemolytic-disease (9) 9
mice, inbred c57bl (9) 9
neutrophils (9) 9
receptors, igg - metabolism (9) 9
biochemistry & molecular biology (8) 8
cells, cultured (8) 8
effector functions (8) 8
enzyme-linked immunosorbent assay (8) 8
fc-gamma-riii (8) 8
immunity (8) 8
molecular sequence data (8) 8
monoclonal antibodies (8) 8
monoclonal-antibody (8) 8
receptors (8) 8
receptors, igg - immunology (8) 8
subclasses (8) 8
surface plasmon resonance (8) 8
activation (7) 7
analysis (7) 7
autoimmune diseases (7) 7
autoimmunity (7) 7
dendritic cells (7) 7
fucosylation (7) 7
half-life (7) 7
immunoglobulin g - genetics (7) 7
infectious diseases (7) 7
proteins (7) 7
receptor (7) 7
receptors, fc - immunology (7) 7
sialylation (7) 7
specific therapeutic activity of chemical compounds ormedicinal preparations (7) 7
antibodies, bacterial - blood (6) 6
autoantibodies - immunology (6) 6
blood cells (6) 6
cell biology (6) 6
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text IgG subclasses and allotypes: From structure to effector functions
by Vidarsson, Gestur and Dekkers, Gillian and Rispens, Theo
Frontiers in Immunology, ISSN 1664-3224, 2014, Volume 5
Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly... 
Fc receptors | Immunoglobulin G | Genetic | IgG | Glycosylation | Neonatal Fc receptor | Polymorphism | genetic | MOLECULAR CHARACTERIZATION | immunoglobulin G | FAB-ARM EXCHANGE | ANTIINFLAMMATORY ACTIVITY | HEMOLYTIC-DISEASE | glycosylation | polymorphism | HIGH-AFFINITY BINDING | IMMUNOLOGY | AMINO-ACID SUBSTITUTION | neonatal Fc receptor | HUMAN-IMMUNOGLOBULIN-G | HEAVY-CHAIN | NEONATAL FC-RECEPTOR | GAMMA RECEPTOR | Neonatal Fc Receptor (FcRn) | Polymorphism, Genetic
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Novel concepts of altered immunoglobulin G galactosylation in autoimmune diseases
by Dekkers, Gillian and Rispens, Theo and Vidarsson, Gestur
Frontiers in Immunology, ISSN 1664-3224, 03/2018, Volume 9, p. 553
The composition of the conserved N297 glycan in immunoglobulin G (IgG) has been shown to affect antibody effector functions C1q of the complement system and Fc... 
Antibody effector functions | Autoimmunity | Fc gamma receptor | Complement | Immune regulation | Galactosylation | Immunoglobulin G glycosylation | Immunoglobulin G | Physiological aspects | Development and progression | Glycosylation | Genetic aspects | Research | Autoimmune diseases | immunoglobulin G glycosylation | galactosylation | autoimmunity | complement | immune regulation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Macrophages eliminate circulating tumor cells after monoclonal antibody therapy
by Gül, Nuray and Babes, Liane and Siegmund, Kerstin and Korthouwer, Rianne and Bögels, Marijn and Braster, Rens and Vidarsson, Gestur and ten Hagen, Timo L. M and Kubes, Paul and van Egmond, Marjolein
Journal of clinical investigation, ISSN 0021-9738, 2014, Volume 124, Issue 2, pp. 812 - 823
The use of monoclonal antibodies (mAbs) as therapeutic tools has increased dramatically in the last decade and is now one of the mainstream strategies to treat... 
LIVER METASTASES | MEDICINE, RESEARCH & EXPERIMENTAL | TARGETED THERAPIES | ACTIVATION | COLORECTAL-CANCER | LYMPHOMA DEPLETION | RITUXIMAB | CD20 IMMUNOTHERAPY | FC-GAMMA-RI | C-RECEPTOR POLYMORPHISMS | EXPRESSION | Neoplasm Transplantation | Liver - pathology | Reactive Oxygen Species | Kupffer Cells - cytology | Bone Marrow Cells - cytology | Humans | Immunoglobulin G - chemistry | Liver - metabolism | Mice, Inbred C57BL | Neoplastic Cells, Circulating - metabolism | Antibodies, Monoclonal - therapeutic use | Reactive Nitrogen Species | Macrophages - metabolism | Neoplasm Metastasis | Animals | Melanoma, Experimental | Neoplasms - immunology | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Antibodies, Monoclonal - chemistry | Microscopy, Fluorescence | Phagocytosis | Cancer cells | Monoclonal antibodies | Physiological aspects | Dosage and administration | Research | Macrophages | Flow cytometry | Chemotherapy | Microscopy | Rodents | Cytotoxicity | Breast cancer | Laboratory animals | Experiments | Cancer therapies | Success | Immune system | Tumors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Antibodies and their receptors: Different potential roles in mucosal defense
by Horton, Rachel E and Vidarsson, Gestur
Frontiers in Immunology, ISSN 1664-3224, 2013, Volume 4, p. 200
Over recent years it has become increasingly apparent that mucosal antibodies are not only restricted to the IgM and IgA isotypes, but that also other isotypes... 
IgG | IgA | Mucosal | Antibody | IgM | IgD | antibody | IMMUNOLOGY | mucosal | Antibodies | FcRn | Fc receptors | IgG subclasses and allotypes | antibody isotypes | mucosal immunity
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Multi-level glyco-engineering techniques to generate IgG with defined Fc-glycans
by Dekkers, Gillian and Plomp, Rosina and Koeleman, Carolien A. M and Visser, Remco and von Horsten, Hans H and Sandig, Volker and Rispens, Theo and Wuhrer, Manfred and Vidarsson, Gestur
Scientific reports, ISSN 2045-2322, 2016, Volume 6, Issue 1, p. 36964
Immunoglobulin G (IgG) mediates its immune functions through complement and cellular IgG-Fc receptors (Fc gamma R). IgG contains an evolutionary conserved... 
COEXPRESSION | MULTIDISCIPLINARY SCIENCES | SIALYLATION | GAMMA-RIII | THERAPEUTIC ANTIBODIES | N-GLYCOSYLATION | FUCOSYLATION | IMMUNOGLOBULIN-G | MASS-SPECTROMETRY | ANTIBODY EFFECTOR FUNCTIONS | PREGNANCY | Fc receptors | Polysaccharides | N-Acetylglucosamine | Evolutionary conservation | Immunoglobulin G | Monoclonal antibodies | Glycosylation | Glycoproteins | Galactose | Fucose
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential
by Stapleton, Nigel M and Andersen, Jan Terje and Stemerding, Annette M and Bjarnarson, Stefania P and Verheul, Ruurd C and Gerritsen, Jacoline and Zhao, Yixian and Kleijer, Marion and Sandlie, Inger and de Haas, Masja and Jonsdottir, Ingileif and van der Schoot, C. Ellen and Vidarsson, Gestur
Nature communications, ISSN 2041-1723, 2011, Volume 2, Issue 1, p. 599
Human IgG3 displays the strongest effector functions of all IgG subclasses but has a short half-life for unresolved reasons. Here we show that IgG3 binds to... 
COMPLEX | CHIMERIC ANTIBODIES | GAMMA RECEPTORS | SUBCLASSES | AFFINITY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | I-RELATED RECEPTOR | BINDING DOMAIN | IMMUNOGLOBULIN-G | ANTIGEN | Pneumococcal Infections - drug therapy | Agammaglobulinemia - immunology | Pneumococcal Infections - metabolism | Arginine - immunology | Humans | Receptors, Fc - metabolism | Half-Life | Antibodies, Monoclonal - therapeutic use | Histidine - metabolism | Agammaglobulinemia - metabolism | Streptococcus pneumoniae - immunology | Histocompatibility Antigens Class I - metabolism | Protein Transport - immunology | Agammaglobulinemia - pathology | Pneumococcal Infections - immunology | Agammaglobulinemia - drug therapy | Immunoglobulin G - immunology | Arginine - genetics | Antibodies, Monoclonal - immunology | Molecular Targeted Therapy - methods | Disease Models, Animal | Binding, Competitive | Streptococcus pneumoniae - drug effects | Histocompatibility Antigens Class I - immunology | Histidine - genetics | Immunoglobulin G - therapeutic use | Histidine - immunology | Immunoglobulin G - administration & dosage | Animals | Receptors, Fc - immunology | Antibodies, Monoclonal - administration & dosage | Cell Line, Tumor | Protein Binding | Mice | Antibodies, Monoclonal - metabolism | Arginine - metabolism | Amino Acid Substitution | Hydrogen-Ion Concentration | Immunoglobulin G - metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text The neonatal Fc receptor as therapeutic target in IgG-mediated autoimmune diseases
by Sesarman, Alina and Vidarsson, Gestur and Sitaru, Cassian
Cellular and Molecular Life Sciences, ISSN 1420-682X, 8/2010, Volume 67, Issue 15, pp. 2533 - 2550
Therapy approaches based on lowering levels of pathogenic autoantibodies represent rational, effective, and safe treatment modalities of autoimmune diseases.... 
Life Sciences | Biochemistry, general | Autoimmunity | Immunoapheresis | IgG homeostasis | Life Sciences, general | Engineered IgG | Autoantibody | Therapeutic IgG | Biomedicine general | Cell Biology | SYSTEMIC-LUPUS-ERYTHEMATOSUS | IMMUNE THROMBOCYTOPENIC PURPURA | BIOCHEMISTRY & MOLECULAR BIOLOGY | GUILLAIN-BARRE-SYNDROME | IMMUNOGLOBULIN TRANSPORT PATHWAY | RANDOMIZED CONTROLLED-TRIAL | CELL BIOLOGY | I-RELATED RECEPTOR | ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODIES | EPIDERMOLYSIS-BULLOSA-ACQUISITA | CENTRAL-NERVOUS-SYSTEM | EXTRACELLULAR-MATRIX PROTEIN-1 | Antibodies - metabolism | Serum - metabolism | Receptors, Fc - metabolism | Autoimmune Diseases - immunology | Histocompatibility Antigens Class I | Half-Life | Rats | Serum - immunology | Autoantibodies - immunology | Animals | Immunoglobulin Fc Fragments - immunology | Receptors, Fc - immunology | Antibodies - immunology | Autoimmune Diseases - therapy | Antibodies - blood | Mice | Autoimmune Diseases - drug therapy | Infants (Newborn) | Fc receptors | Autoantibodies | Autoimmune diseases | Immunoglobulin G | Proteins | Immunoglobulins | Cellular biology | Immunotherapy | Homeostasis | Gene expression
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Human IgG Subclasses
by Vidarsson, Gestur and Rispens, Theo
2014, 19
Immunoglobulin G | Amino acids | Glycoproteins | B cells
Reference
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Dimeric IgG complexes from IVIg are incapable of inducing in vitro neutrophil degranulation or complement activation
by Kustiawan, Iwan and Derksen, Ninotska I. L and Guhr, Theresa and Kruithof, Simone and Jiskoot, Wim and Vidarsson, Gestur and Rispens, Theo
PLoS ONE, ISSN 1932-6203, 04/2018, Volume 13, Issue 4, p. e0195729
Purpose Intravenous immunoglobulin (IVIg) products contain various amounts of dimeric IgG complexes. Current insights into the possible biological activities... 
IMMUNE-COMPLEXES | ANTIBODIES | GLOBULIN | FC-GAMMA | STIMULATION | THERAPEUTIC-EFFICACY | MULTIDISCIPLINARY SCIENCES | THROMBOCYTOPENIC PURPURA | INTRAVENOUS IMMUNOGLOBULIN PREPARATIONS | Fc receptors | Research | Immunoglobulin G | Analysis | Neutrophils | Immunoglobulins | Intravenous administration | Blood & organ donations | Laboratories | Activation | Studies | Signal transduction | Receptors | Complement activation | Cell activation | Degranulation | Dimers
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Antigen specificity determines anti-red blood cell IgG-Fc alloantibody glycosylation and thereby severity of haemolytic disease of the fetus and newborn
by Sonneveld, Myrthe E and Koelewijn, Joke and de Haas, Masja and Admiraal, Jon and Plomp, Rosina and Koeleman, Carolien A. M and Hipgrave Ederveen, Agnes L and Ligthart, Peter and Wuhrer, Manfred and van der Schoot, C. Ellen and Vidarsson, Gestur
British journal of haematology, ISSN 0007-1048, 2017, Volume 176, Issue 4, pp. 651 - 660
Haemolytic disease of the fetus and newborn (HDFN) is a severe disease in which fetal red blood cells (RBC) are destroyed by maternal anti-RBC IgG... 
Red cell antigens | Antibodies | Immunology | Haemolytic anaemia | Fc‐glycosylation | Fc-glycosylation | KELL ANTIBODIES | MANAGEMENT | FETAL ANEMIA | RISK | CONFORMATION | PREGNANCY | IMMUNIZATION | FUCOSYLATION | HEMATOLOGY | Erythrocytes - immunology | Severity of Illness Index | Immunoglobulin Fc Fragments - metabolism | Humans | Male | Erythroblastosis, Fetal - diagnosis | Glycosylation | Erythroblastosis, Fetal - immunology | Isoantibodies - blood | Pregnancy | Blood Group Antigens - immunology | Adult | Female | Infant, Newborn | Anemia | Pregnant women | Immunity | Immunoglobulin G | Antigens | Immunization | Fetuses | Blood cells | Erythrocytes | Blood | Fc receptors | Red blood cells | Alloantibodies
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Decoding the Human Immunoglobulin G-Glycan Repertoire Reveals a Spectrum of Fc-Receptor- and Complement-Mediated-Effector Activities
by Dekkers, Gillian and Treffers, Louise and Plomp, Rosina and Bentlage, Arthur E. H and de Boer, Marcella and Koeleman, Carolien A. M and Lissenberg-Thunnissen, Suzanne N and Visser, Remco and Brouwer, Mieke and Mok, Juk Yee and Matlung, Hanke and van den Berg, Timo K and van Esch, Wim J. E and Kuijpers, Taco W and Wouters, Diana and Rispens, Theo and Wuhrer, Manfred and Vidarsson, Gestur
Frontiers in immunology, ISSN 1664-3224, 2017, Volume 8
Glycosylation of the immunoglobulin G (IgG)-Fc tail is required for binding to Fc-gamma receptors (FcγRs) and complement-component C1q. A variety of... 
Antibody effector functions | Complement | Antibody-dependent cellular cytotoxicity | Fc gamma receptor | Immunoglobulin G glycosylation | C-REACTIVE PROTEIN | RHEUMATOID-ARTHRITIS | ANTIINFLAMMATORY ACTIVITY | HEMOLYTIC-DISEASE | IGG | MONOCLONAL-ANTIBODY | N-GLYCOSYLATION | IMMUNOLOGY | MASS-SPECTROMETRY | DEPENDENT CELLULAR CYTOTOXICITY | GAMMA-RIIIA BINDING | antibody-dependent cellular cytotoxicity | antibody effector functions | immunoglobulin G glycosylation | complement
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights