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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2013, Volume 110, Issue 33, pp. 13528 - 13533
Journal Article
Frontiers in Physiology, ISSN 1664-042X, 2010, Volume 1
Epoxyeicosatrienoic acids (EETs) contribute importantly to the regulation of vascular tone and blood pressure control. The purpose of this study was to develop... 
Epoxyeicosanoids | Hypertension | Blood pressure | Afferent arteriole | Vasodilation | blood pressure | PHYSIOLOGY | afferent arteriole | epoxyeicosanoids | vasodilation | hypertension | Blood Pressure
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 10/2019, Volume 29, Issue 19, p. 126616
19-Hydroxyeicosatetraenoic acid (19-HETE, ), a metabolically and chemically labile cytochrome P450 eicosanoid, has diverse biological activities including... 
Hypertension | Bioisosteric replacement | Antagonist | Eicosanoid | Vascular sensitization | 20-HETE | CYTOCHROME-P450 | EICOSANOIDS | CHEMISTRY, MEDICINAL | CHEMISTRY, ORGANIC | ARACHIDONIC-ACID | AGONISTS | METABOLISM | ENZYMES
Journal Article
Journal Article
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 09/2011, Volume 22, Issue 17, pp. 2994 - 3009
Journal Article
Journal Article
Journal Article
NITRIC OXIDE-BIOLOGY AND CHEMISTRY, ISSN 1089-8603, 09/2013, Volume 33, pp. 18 - 41
We have previously demonstrated that a stable synthetic analog of 20-hydroxyeicosatetraenoic acid (20-HETE),... 
COX-2 | iNOS/sGC/PKG pathway | VASOACTIVE EICOSANOIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOTHELIUM-DEPENDENT VASOCONSTRICTOR | 20-HYDROXYEICOSATETRAENOIC ACID | CYP4A1 | ENDOTOXIN-INDUCED HYPOTENSION | ARACHIDONIC-ACID | Endotoxin | DIFFERENTIAL REGULATION | Hypotension | gp91(phox)/NOX2 | CORONARY-ARTERIES | CELL BIOLOGY | NITRIC-OXIDE PRODUCTION | TREATMENT IN-VIVO | CYTOCHROME-P450 4A ACTIVITY | Membrane Glycoproteins - metabolism | Rats, Wistar | Lipopeptides - pharmacology | NADPH Oxidases - metabolism | Cytochrome P-450 Enzyme System - metabolism | Male | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Cyclic GMP-Dependent Protein Kinases - metabolism | Shock, Septic - metabolism | Cyclooxygenase 2 - genetics | Hydroxyeicosatetraenoic Acids - pharmacology | Protective Agents - pharmacology | Shock, Septic - drug therapy | Microfilament Proteins - metabolism | Disease Models, Animal | Shock, Septic - genetics | RNA, Messenger - genetics | Rats | Guanylate Cyclase - metabolism | Soluble Guanylyl Cyclase | Random Allocation | Organ Specificity | Cell Adhesion Molecules - metabolism | NADPH Oxidase 2 | Animals | Nitric Oxide Synthase Type II - genetics | Signal Transduction - drug effects | Cyclooxygenase 2 - metabolism | Lipopolysaccharides - pharmacology | Peroxynitrous Acid - metabolism | Cytochrome P-450 Enzyme System - genetics | HSP90 Heat-Shock Proteins - metabolism | Shock, Septic - enzymology | Nitric Oxide Synthase Type II - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism
Journal Article