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BBA - Molecular Basis of Disease, ISSN 0925-4439, 12/2018, Volume 1864, Issue 12, p. 3697
Familial Hypercholesterolemia (FH) is an autosomal co-dominant genetic disorder characterized by elevated low-density lipoprotein (LDL) cholesterol levels and... 
Antigens | Enzymes | Hypercholesterolemia | Low density lipoproteins | Atherosclerosis | Genetic aspects | Genetic engineering | Mitochondrial DNA | Cholesterol
Journal Article
ORPHANET JOURNAL OF RARE DISEASES, ISSN 1750-1172, 02/2017, Volume 12
Background: Gaucher disease (GD) is caused by mutations in the GBA1 gene which encodes lysosomal beta-glucocerebrosidase (GCase). In GD, partial or complete... 
MEDICINE, RESEARCH & EXPERIMENTAL | Oxidative stress | Efferocytosis | Coenzyme Q | Inflammasome | MITOPHAGY | AUTOPHAGY | LYSOSOMAL STORAGE DISORDERS | DEFICIENCY | Mitochondria | Gaucher disease | MOUSE MODEL | GENETICS & HEREDITY | TRIGGERS MITOCHONDRIA DEGRADATION | MICE | DYSFUNCTION | ACCUMULATION | PARKINSONS-DISEASE
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2017, Volume 797, pp. 75 - 82
Amitriptyline, a tricyclic antidepressant, has been proposed as an antitumoral drug in oxidative therapy. Its pro-apoptotic effects, mediated by high reactive... 
Antioxidants | Oxidative stress | Coenzyme Q | Amitriptyline | Oxidative therapy
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 02/2017, Volume 797, p. 75
Amitriptyline, a tricyclic antidepressant, has been proposed as an antitumoral drug in oxidative therapy. Its pro-apoptotic effects, mediated by high reactive... 
Antioxidants | Physiological aspects | Enzymes | Amitriptyline | Lung cancer, Non-small cell
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 02/2017, Volume 797, pp. 75 - 82
Amitriptyline, a tricyclic antidepressant, has been proposed as an antitumoral drug in oxidative therapy. Its pro-apoptotic effects, mediated by high reactive... 
Antioxidants | Oxidative stress | Amitriptyline | Coenzyme Q10 | Oxidative therapy
Journal Article
International Journal of Molecular Sciences, ISSN 1422-0067, 10/2019, Volume 20, Issue 20, p. 5195
Atherosclerosis is the most common cause of cardiac deaths worldwide. Classically, atherosclerosis has been explained as a simple arterial lipid deposition... 
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 12/2018, Volume 1864, Issue 12, pp. 3697 - 3713
Familial Hypercholesterolemia (FH) is an autosomal co-dominant genetic disorder characterized by elevated low-density lipoprotein (LDL) cholesterol levels and... 
Mitochondria dysfunction | LDL-R | Inflammasome | Coenzyme Q10 deficiency | Mitophagy | Familial Hypercholesterolemia | Cholesterol | deficiency | Coenzyme Q
Journal Article
Orphanet Journal of Rare Diseases, ISSN 1750-1172, 02/2017, Volume 12, Issue 1, pp. 1 - 15
Gaucher disease (GD) is caused by mutations in the GBA1 gene which encodes lysosomal [beta]-glucocerebrosidase (GCase). In GD, partial or complete loss of... 
Efferocytosis | Oxidative stress | Mitochondria | Inflammasome | Gaucher disease | Coenzyme Q10 | Care and treatment | Coenzymes | Physiological aspects | Genetic aspects | Research | Diagnosis | Macrophages | Risk factors | Gaucher's disease
Journal Article
Journal Article
Journal Article
Genes and Cancer, ISSN 1947-6019, 07/2016, Volume 7, Issue 7-8, pp. 260 - 277
Systemic treatments for hepatocellular carcinoma (HCC) have been largely unsuccessful. This study investigated the antitumoral activity of Amitriptyline, a... 
Oxidative stress | Amitriptyline | HepG2 cells | Mitophagy | Apoptosis | amitriptyline | apoptosis | mitophagy | Research Paper | oxidative stress
Journal Article