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1. Full Text Sepsis definitions: time for change
by Vincent, Jean-Louis, Prof and Opal, Steven M, Prof and Marshall, John C, Prof and Tracey, Kevin J, Prof
Lancet, The, ISSN 0140-6736, 2013, Volume 381, Issue 9868, pp. 774 - 775
  [...]some degree of host response is actually inherent to the infection; indeed, this is an important component of the difference between infection and mere... 
Internal Medicine | ILL | MEDICINE, GENERAL & INTERNAL | INFECTION | INFLAMMATION | Sepsis - etiology | Sepsis - immunology | Systemic Inflammatory Response Syndrome - physiopathology | Humans | Systemic Inflammatory Response Syndrome - immunology | Sepsis - diagnosis | Systemic Inflammatory Response Syndrome - etiology | Sepsis - physiopathology | Systemic Inflammatory Response Syndrome - diagnosis | Cardiac arrhythmia | Genotype & phenotype | Bacterial infections | Sepsis | Infections | Pattern recognition | Autoimmune diseases | Patients | Viral infections | Fever | Immune system
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2. Full Text Sepsis: a roadmap for future research
by Cohen, Jonathan, Prof and Vincent, Jean-Louis, Prof and Adhikari, Neill K J, MDCM and Machado, Flavia R, MD and Angus, Derek C, Prof and Calandra, Thierry, Prof and Jaton, Katia, PhD and Giulieri, Stefano, MD and Delaloye, Julie, MD-PhD and Opal, Steven, Prof and Tracey, Kevin, Prof and van der Poll, Tom, Prof and Pelfrene, Eric, FRCP
Lancet Infectious Diseases, The, ISSN 1473-3099, 2015, Volume 15, Issue 5, pp. 581 - 614
Summary Sepsis is a common and lethal syndrome: although outcomes have improved, mortality remains high. No specific anti-sepsis treatments exist; as such,... 
Infectious Disease | COMBINATION ANTIMICROBIAL THERAPY | INFECTIOUS DISEASES | TUMOR-NECROSIS-FACTOR | FLIGHT MASS-SPECTROMETRY | POLYMERASE-CHAIN-REACTION | DESORPTION IONIZATION-TIME | CAMPAIGN INTERNATIONAL GUIDELINES | INTENSIVE-CARE UNITS | PLACEBO-CONTROLLED TRIAL | CRITICALLY-ILL PATIENTS | BLOOD-STREAM INFECTIONS | Humans | Sepsis - epidemiology | Sepsis - diagnosis | Biomedical Research - trends | Clinical Trials as Topic | Molecular Targeted Therapy | Forecasting | Incidence | Host-Pathogen Interactions | Anti-Bacterial Agents - therapeutic use | Sepsis - drug therapy | Disease Management | Sepsis - microbiology | Immunologic Factors - therapeutic use | Precision Medicine | Medical colleges | Mortality | Analysis | Multidrug resistant organisms | Respiratory distress syndrome | Drug therapy | Immune system
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3. Full Text Ethics and end-of-life care for adults in the intensive care unit
by Curtis, J Randall, Prof and Vincent, Jean-Louis, Prof
Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9749, pp. 1347 - 1353
Summary The intensive care unit (ICU) is where patients are given some of the most technologically advanced life-sustaining treatments, and where difficult... 
Internal Medicine | Decision Making | Interdisciplinary Communication | Terminal Care - ethics | Resource Allocation | Humans | Intensive Care Units - ethics | Patient Admission | Adult | Professional-Family Relations | Withholding Treatment | Communication | Intensive care units | Services | Terminal care | Social aspects | Methods | Ethical aspects | Medical ethics | Critical care | Hospitals | Decision making | Mortality | Medical personnel | Training | Ethics | culture | Communications | Occupational health | burnout | intensive care units
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4. Full Text Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: a prospective cohort study
by Levy, Mitchell M, Prof and Artigas, Antonio, Prof and Phillips, Gary S, MAS and Rhodes, Andrew, MBBS and Beale, Richard, MBBS and Osborn, Tiffany, MD and Vincent, Jean-Louis, Prof and Townsend, Sean, MD and Lemeshow, Stanley, Prof and Dellinger, R Phillip, Prof
Lancet Infectious Diseases, The, ISSN 1473-3099, 2012, Volume 12, Issue 12, pp. 919 - 924
Summary Background Mortality from severe sepsis and septic shock differs across continents, countries, and regions. We aimed to use data from the Surviving... 
Infectious Disease | ADMISSIONS | MORTALITY | INFECTIOUS DISEASES | STATES | MANAGEMENT | GUIDELINES | SEPTIC SHOCK | KINGDOM | Length of Stay | United States - epidemiology | Prospective Studies | Humans | Europe - epidemiology | Intensive Care Units - statistics & numerical data | Treatment Outcome | Shock, Septic - mortality | Shock, Septic - therapy | Sepsis - mortality | Regression Analysis | Guideline Adherence | Sepsis - therapy | Cohort Studies | Medical colleges | Emergency medicine | Analysis | Mortality | Septic shock | Health aspects | Public health | Intensive care units | Databases | Hospitals | Data processing | Sepsis | Models
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5. Full Text Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit
by Vincent, Jean-Louis, Prof and Marshall, John C, Prof and Ñamendys-Silva, Silvio A, MD and François, Bruno, Prof and Martin-Loeches, Ignacio, MD and Lipman, Jeffrey, Prof and Reinhart, Konrad, Prof and Antonelli, Massimo, Prof and Pickkers, Peter, MD and Njimi, Hassane, PhD and Jimenez, Edgar, MD and Sakr, Yasser, MD and ICON Investigators and ICON investigators
Lancet Respiratory Medicine, The, ISSN 2213-2600, 2014, Volume 2, Issue 5, pp. 380 - 386
Summary Background Global epidemiological data regarding outcomes for patients in intensive care units (ICUs) are scarce, but are important in understanding... 
Pulmonary/Respiratory | MULTILEVEL LOGISTIC-REGRESSION | DEFINITIONS | EMERGENCY | MULTICENTER | RESPIRATORY SYSTEM | OUTCOMES | MEDICINE | UNITS | EPIDEMIOLOGY | ACCESS | SEVERE SEPSIS | Critical Illness - mortality | Intensive Care Units | Global Health | Hospital Mortality | Outcome Assessment (Health Care) | Comorbidity | Humans | Medical Audit | Cohort Studies | Sepsis - mortality | Life Sciences | Human health and pathology | Pulmonology and respiratory tract
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6. Full Text Efficacy of the MAGE-A3 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small-cell lung cancer (MAGRIT): a randomised, double-blind, placebo-controlled, phase 3 trial
by Vansteenkiste, Johan F, Prof Dr and Cho, Byoung Chul, MD and Vanakesa, Tonu, MD and De Pas, Tommaso, MD and Zielinski, Marcin, Prof and Kim, Moon Soo, MD and Jassem, Jacek, Prof and Yoshimura, Masahiro, MD and Dahabreh, Jubrail, MD and Nakayama, Haruhiku, MD and Havel, Libor, MD and Kondo, Haruhiko, MD and Mitsudomi, Tetsuya, Prof and Zarogoulidis, Konstantinos, Prof and Gladkov, Oleg A, MD and Udud, Katalin, MD and Tada, Hirohito, MD and Hoffman, Hans, Prof and Bugge, Anders, MD and Taylor, Paul, MD and Gonzalez, Emilio Esteban, Prof and Liao, Mei Lin, Prof and He, Jianxing, MD and Pujol, Jean-Louis, Prof and Louahed, Jamila, PhD and Debois, Muriel, MSc and Brichard, Vincent, MD and Debruyne, Channa, MD and Therasse, Patrick, MD and Altorki, Nasser, MD
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 6, pp. 822 - 835
Summary Background Fewer than half of the patients with completely resected non-small-cell lung cancer (NSCLC) are cured. Since the introduction of adjuvant... 
Hematology, Oncology and Palliative Medicine | RESPONSES | PROTEIN | CISPLATIN | ONCOLOGY | STAGE-IB | VACCINATION | ANTIGENS | EXPRESSION | SIGNATURE | CHEMOTHERAPY | Lung Neoplasms - drug therapy | Prognosis | Follow-Up Studies | Humans | Lung Neoplasms - metabolism | Middle Aged | Neoplasm Proteins - immunology | Neoplasm Recurrence, Local - drug therapy | Lung Neoplasms - pathology | Male | Neoplasm Proteins - metabolism | Neoplasm Recurrence, Local - immunology | Neoplasm Recurrence, Local - pathology | Immunotherapy | Antigens, Neoplasm - metabolism | Biomarkers, Tumor - metabolism | Immunoconjugates - therapeutic use | Female | Chemotherapy, Adjuvant | Carcinoma, Non-Small-Cell Lung - pathology | Double-Blind Method | Neoplasm Recurrence, Local - metabolism | Antigens, Neoplasm - immunology | Carcinoma, Non-Small-Cell Lung - metabolism | Survival Rate | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - immunology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Neoplasm Staging | Medical colleges | Care and treatment | Sarcoma | Adjuvant treatment | Clinical trials | Respiratory agents | Lung cancer, Non-small cell | Health aspects | Cancer | Analysis | Life Sciences
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7. Full Text Mortality after surgery in Europe: a 7 day cohort study
by Pearse, Rupert M, Dr and Moreno, Rui P, Prof and Bauer, Peter, Prof and Pelosi, Paolo, Prof and Metnitz, Philipp, Prof and Spies, Claudia, Prof and Vallet, Benoit, Prof and Vincent, Jean-Louis, Prof and Hoeft, Andreas, Prof and Rhodes, Andrew, FRCP and Trial Grp European Soc Intensive and Trial Grp European Soc and European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society of Intensive Care Medicine and the European Society of Anaesthesiology
Lancet, The, ISSN 0140-6736, 2012, Volume 380, Issue 9847, pp. 1059 - 1065
Summary Background Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and... 
Internal Medicine | POPULATION | MEDICINE, GENERAL & INTERNAL | NONCARDIAC SURGERY | POSTOPERATIVE COMPLICATIONS | CANCER-SURGERY | LONG-TERM SURVIVAL | SURGICAL QUALITY IMPROVEMENT | RISK | INPATIENT SURGERY | CRITICAL-CARE | MAJOR SURGERY | Critical Care - statistics & numerical data | Hospital Mortality | Surgical Procedures, Operative - mortality | Humans | Middle Aged | Europe - epidemiology | Hospitalization - statistics & numerical data | Male | Treatment Outcome | Postoperative Care - methods | Adult | Female | Postoperative Care - statistics & numerical data | Aged | Length of Stay - statistics & numerical data | Cohort Studies | Austria | Demographic aspects | Mortality | United Kingdom | Portugal | Postoperative care | Health aspects | Risk factors
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